TAXONOMY

Nature Subjects Taxonomy

CONCEPT NAME

Thrombotic microangiopathies

DESCRIPTION

Thrombotic microangiopathies are a group of diseases caused by thrombosis in the microvasculature, they most frequently affect the brain and kidneys. Two prominent causes are thrombotic thrombocytopenic purpura and haemolytic uremic syndrome.

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20 TRIPLES      15 PREDICATES      20 URIs      8 LITERALS

Subject Predicate Object
1 subjects:thrombotic-microangiopathies npg:name Rebecca Kirk
2 dcterms:modified 2017-10-09T07:40:46+00:00
3 sg:license http://scigraph.springernature.com/explorer/license/
4 rdf:type npg:Subject
5 sg:Subject
6 skos:Concept
7 rdfs:label Thrombotic microangiopathies
8 skos:altLabel Thrombotic Microangiopathy
9 skos:broader subjects:kidney-diseases
10 skos:closeMatch dbpedia:Thrombotic_microangiopathies
11 mesh:D057049
12 skos:definition Thrombotic microangiopathies are a group of diseases caused by thrombosis in the microvasculature, they most frequently affect the brain and kidneys. Two prominent causes are thrombotic thrombocytopenic purpura and haemolytic uremic syndrome.
13 skos:hiddenLabel thrombotic-microangiopathies
14 skos:historyNote [skos:definition - 2014.01.21] Diseases that result in THROMBOSIS in MICROVASCULATURE. The two most prominent diseases are PURPURA, THROMBOTIC THROMBOCYTOPENIC; and HEMOLYTIC-UREMIC SYNDROME. Multiple etiological factors include VASCULAR ENDOTHELIAL CELL damage due to SHIGA TOXIN; FACTOR H deficiency; and aberrant VON WILLEBRAND FACTOR formation.
15 skos:inScheme subjects:
16 skos:narrower subjects:haemolytic-uremic-syndrome
17 subjects:idiopathic-thrombocytopaenic-purpura
18 subjects:thrombotic-thrombocytopaenic-purpura
19 skos:notation thrombotic-microangiopathies
20 skos:prefLabel Thrombotic microangiopathies
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