TAXONOMY

Nature Subjects Taxonomy

CONCEPT NAME

Sphingolipids

DESCRIPTION

Sphingolipids are lipids with a sphingoid base backbone, bearing its own hydrocarbon chain, an amine group and two hydroxyl groups. The amine group is bonded to a fatty acid of varying length and one of the hydroxyl groups may be functionalized to a phosphate or carbohydrate. Sphingolipids are involved in signal transduction across membranes.

Related objects

BROADER TERMS

  • Lipids

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    16 TRIPLES      13 PREDICATES      16 URIs      7 LITERALS

    Subject Predicate Object
    1 subjects:sphingolipids dcterms:modified 2017-10-09T07:41:19+00:00
    2 sg:license http://scigraph.springernature.com/explorer/license/
    3 rdf:type npg:Subject
    4 sg:Subject
    5 skos:Concept
    6 rdfs:label Sphingolipids
    7 skos:altLabel Lysosphingolipids
    8 skos:broader subjects:lipids
    9 skos:closeMatch dbpedia:Sphingolipids
    10 mesh:D013107
    11 skos:definition Sphingolipids are lipids with a sphingoid base backbone, bearing its own hydrocarbon chain, an amine group and two hydroxyl groups. The amine group is bonded to a fatty acid of varying length and one of the hydroxyl groups may be functionalized to a phosphate or carbohydrate. Sphingolipids are involved in signal transduction across membranes.
    12 skos:hiddenLabel sphingolipids
    13 skos:historyNote [skos:definition - 2014.01.21] A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a p olar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed)
    14 skos:inScheme subjects:
    15 skos:notation sphingolipids
    16 skos:prefLabel Sphingolipids
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