TAXONOMY

Nature Subjects Taxonomy

CONCEPT NAME

Long-term depression

DESCRIPTION

Long-term depression (LTD) is the biological process by which certain types of synaptic stimulation – such as prolonged low frequency input – result in a long-lasting decrease in the strength of synaptic transmission. It is thought that the mechanisms underlying LTD, together with those underlying long-term potentiation, may contribute to synaptic plasticity during learning.

Related objects

BROADER TERMS

  • Synaptic Plasticity

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    15 TRIPLES      13 PREDICATES      15 URIs      7 LITERALS

    Subject Predicate Object
    1 subjects:long-term-depression dcterms:modified 2017-10-09T07:40:24+00:00
    2 sg:license http://scigraph.springernature.com/explorer/license/
    3 rdf:type npg:Subject
    4 sg:Subject
    5 skos:Concept
    6 rdfs:label Long-term depression
    7 skos:altLabel Depotentiation
    8 skos:broader subjects:synaptic-plasticity
    9 skos:closeMatch dbpedia:Long-term_depression
    10 skos:definition Long-term depression (LTD) is the biological process by which certain types of synaptic stimulation – such as prolonged low frequency input – result in a long-lasting decrease in the strength of synaptic transmission. It is thought that the mechanisms underlying LTD, together with those underlying long-term potentiation, may contribute to synaptic plasticity during learning.
    11 skos:hiddenLabel long-term-depression
    12 skos:historyNote [skos:definition - 2014.01.21] Long-term depression (LTD), in neurophysiology, is an activity-dependent reduction in the efficacy of neuronal synapses lasting hours or longer. LTD occurs in many areas of the CNS with varying mechanisms depending upon brain region and developmental progress.
    13 skos:inScheme subjects:
    14 skos:notation long-term-depression
    15 skos:prefLabel Long-term depression
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