TAXONOMY

Nature Subjects Taxonomy

CONCEPT NAME

Genetic linkage study

DESCRIPTION

A genetic linkage study is a family-based method used to map a trait to a genomic location by demonstrating co-segregation of the disease with genetic markers of known chromosomal location; locations identified are more likely to contain a causal genetic variant. This technique is particularly useful for the identification of genes that are inherited in a Mendelian fashion.

Related objects

BROADER TERMS

  • Genetics

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    18 TRIPLES      14 PREDICATES      18 URIs      9 LITERALS

    Subject Predicate Object
    1 subjects:genetic-linkage-study dcterms:modified 2017-10-09T07:39:47+00:00
    2 sg:license http://scigraph.springernature.com/explorer/license/
    3 rdf:type npg:Subject
    4 sg:Subject
    5 skos:Concept
    6 rdfs:label Genetic linkage study
    7 skos:altLabel Genetic Linkage
    8 Genetic Linkage Analyses
    9 Genetic Linkage Analysis
    10 skos:broadMatch dbpedia:Genetic_linkage
    11 skos:broader subjects:genetics
    12 skos:closeMatch mesh:D008040
    13 skos:definition A genetic linkage study is a family-based method used to map a trait to a genomic location by demonstrating co-segregation of the disease with genetic markers of known chromosomal location; locations identified are more likely to contain a causal genetic variant. This technique is particularly useful for the identification of genes that are inherited in a Mendelian fashion.
    14 skos:hiddenLabel genetic-linkage-study
    15 skos:historyNote [skos:definition - 2014.01.21] The co-inheritance of two or more non-allelic GENES due to their being located more or less closely on the same CHROMOSOME. The determination of the physical association and distance between of two or more non-allelic GENES by measuring their co-inheritance or mapping their physical location on the same CHROMOSOME.
    16 skos:inScheme subjects:
    17 skos:notation genetic-linkage-study
    18 skos:prefLabel Genetic linkage study
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