TAXONOMY

Nature Subjects Taxonomy

CONCEPT NAME

Chimaerism

DESCRIPTION

Chimaerism is the occurrence in an organism of two or more genetically distinct cell populations derived from more than one individual. For example, in mouse genetics, embryonic stem cells may be aggregated with an 8-cell embryo to form a mouse from both cell types.

Related objects

BROADER TERMS

  • Chromosome Abnormality

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    16 TRIPLES      13 PREDICATES      16 URIs      7 LITERALS

    Subject Predicate Object
    1 subjects:chimaerism dcterms:modified 2017-10-09T07:41:00+00:00
    2 sg:license http://scigraph.springernature.com/explorer/license/
    3 rdf:type npg:Subject
    4 sg:Subject
    5 skos:Concept
    6 rdfs:label Chimaerism
    7 skos:altLabel Microchimerism
    8 skos:broader subjects:chromosome-abnormality
    9 skos:closeMatch dbpedia:Chimaerism
    10 mesh:D046528
    11 skos:definition Chimaerism is the occurrence in an organism of two or more genetically distinct cell populations derived from more than one individual. For example, in mouse genetics, embryonic stem cells may be aggregated with an 8-cell embryo to form a mouse from both cell types.
    12 skos:hiddenLabel chimaerism
    13 skos:historyNote [skos:definition - 2014.01.21] The occurrence in an individual of two or more cell populations of different chromosomal constitutions, derived from different individuals. This contrasts with MOSAICISM in which the different cell populations are derived from a single individual. A low number of circulating cells transferred from one ind ividual to another. This often refers to fetal cells persisting in the material circulation and may play a role in the pathogenesis of AUTOIMMUNE DISEASES.
    14 skos:inScheme subjects:
    15 skos:notation chimaerism
    16 skos:prefLabel Chimaerism
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