YEARS

2004-2013

AUTHORS

Carolyn Y Fang

TITLE

Diet and Breast Density over Time in US Chinese Women

ABSTRACT

Upon migration to the US, Chinese women undergo a transition to increased risk for breast cancer. An understanding of lifestyle changes that occur over time in foreign-born Chinese American women, such as changes in diet, could contribute to our understanding of how acculturative changes, particularly in adulthood, affect breast cancer risk. Breast density represents an especially useful marker of risk because of its strong association with breast cancer, and because change in breast density over time may reflect the effects of recent behaviors and exposures. The objectives of the proposed study are to characterize for the first time changes in diet and breast density over time in first-generation Chinese American women, and to examine dietary and other correlates of change in breast density. We will recruit 420 pre- or peri-menopausal Chinese American women of screening mammography age with US residence <=7 years. Data collection will include baseline questionnaires on dietary intake, acculturation, and health and reproductive histories;4-day dietary recalls;anthropometric measures;serum insulin-like growth factor-l level;and a screening mammogram assessed for breast density. Two follow-up measures of the same factors will be obtained at 12- to 24-month intervals. Changes in diet, other behavioral factors, and breast density will be described, as well as dietary and other correlates of breast density change. The research team and the presence of a sizable Chinese American community in the Philadelphia area offer a first opportunity to examine changes in diet and breast density over time in a unique sample of first-generation Chinese American women. Findings will address the extent to which acculturation-related lifestyle changes contribute to the transition in breast cancer risk experienced by Chinese American women. They will also address the issue of modifiability of breast cancer risk in women regardless of ethnicity by examining changes in risk factors during adulthood and by identifying the specific factors of greatest importance.

FUNDED PUBLICATIONS

  • Acculturation and dietary change among Chinese immigrant women in the United States.
  • Acculturative stress and inflammation among Chinese immigrant women.
  • Adiposity, adult weight gain and mammographic breast density in US Chinese women.
  • Stress is associated with unfavorable patterns of dietary intake among female chinese immigrants.
  • Stress Is Associated with Unfavorable Patterns of Dietary Intake Among Female Chinese Immigrants
  • Acculturation and Dietary Change Among Chinese Immigrant Women in the United States
  • Socio-economic position and lower dietary moderation among Chinese immigrant women in the USA.
  • Stressful life events are associated with insulin resistance among Chinese immigrant women in the United States.
  • Acculturation and Post-Migration Stress in Middle-Aged Chinese Immigrant Women in Philadelphia: Variation between the Fujianese and the non-Fujianese women.
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    26 TRIPLES      17 PREDICATES      27 URIs      9 LITERALS

    Subject Predicate Object
    1 grants:c6e6a390cc992c90731c49dbfc4f7121 sg:abstract Upon migration to the US, Chinese women undergo a transition to increased risk for breast cancer. An understanding of lifestyle changes that occur over time in foreign-born Chinese American women, such as changes in diet, could contribute to our understanding of how acculturative changes, particularly in adulthood, affect breast cancer risk. Breast density represents an especially useful marker of risk because of its strong association with breast cancer, and because change in breast density over time may reflect the effects of recent behaviors and exposures. The objectives of the proposed study are to characterize for the first time changes in diet and breast density over time in first-generation Chinese American women, and to examine dietary and other correlates of change in breast density. We will recruit 420 pre- or peri-menopausal Chinese American women of screening mammography age with US residence <=7 years. Data collection will include baseline questionnaires on dietary intake, acculturation, and health and reproductive histories;4-day dietary recalls;anthropometric measures;serum insulin-like growth factor-l level;and a screening mammogram assessed for breast density. Two follow-up measures of the same factors will be obtained at 12- to 24-month intervals. Changes in diet, other behavioral factors, and breast density will be described, as well as dietary and other correlates of breast density change. The research team and the presence of a sizable Chinese American community in the Philadelphia area offer a first opportunity to examine changes in diet and breast density over time in a unique sample of first-generation Chinese American women. Findings will address the extent to which acculturation-related lifestyle changes contribute to the transition in breast cancer risk experienced by Chinese American women. They will also address the issue of modifiability of breast cancer risk in women regardless of ethnicity by examining changes in risk factors during adulthood and by identifying the specific factors of greatest importance.
    2 sg:endYear 2013
    3 sg:fundingAmount 2810538.0
    4 sg:fundingCurrency USD
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    17 sg:hasFundingOrganization grid-institutes:grid.48336.3a
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    19 sg:language English
    20 sg:license http://scigraph.springernature.com/explorer/license/
    21 sg:scigraphId c6e6a390cc992c90731c49dbfc4f7121
    22 sg:startYear 2004
    23 sg:title Diet and Breast Density over Time in US Chinese Women
    24 sg:webpage http://projectreporter.nih.gov/project_info_description.cfm?aid=7637901
    25 rdf:type sg:Grant
    26 rdfs:label Grant: Diet and Breast Density over Time in US Chinese Women
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