YEARS

2011-2017

AUTHORS

Han-Zhu Qian, Sten H Vermund

TITLE

Multi-component HIV Intervention Packages for Chinese MSM

ABSTRACT

DESCRIPTION (provided by applicant): There is no proven effective prevention intervention specifically for men who have sex with men (MSM) population. Bundling partial measures and optimize combinations of interventions may have a substantial impact on HIV seroincidence. The goal of this study is to develop and pilot test a package of Test and Link-to-Care (TLC)-based interventions for preparation of future community-level randomized clinical trial. The specific aims are: (1) To conduct a systematic review of the literature and mathematical modeling to guide the selection of HIV prevention interventions for MSM in China; (2) To conduct a pilot study to evaluate the feasibility, acceptability and initial efficacy of a multi-component TLC intervention packages among MSM in China; and (3) To refine and finalize menu-driven HIV prevention packages and design a multi-site randomized clinical trial in 12 Chinese cities to evaluate its impact on HIV seroincidence among Chinese MSM. As a team of an expert network of American and Chinese researchers and community members with rich knowledge in the subject domains and substantial experience in China, we will develop a culturally competent and potentially effective intervention packages for Chinese MSM at the end of this project. The rapid rise of HIV epidemic among Chinese MSM and the comprehensive disease prevention networks in China provide unique environment for conducting a large scale community-based clinical trial.

FUNDED PUBLICATIONS

  • Integrated prevention of mother-to-child transmission for human immunodeficiency virus, syphilis and hepatitis B virus in China.
  • Sex with women among men who have sex with men in China: prevalence and sexual practices.
  • Threshold virus dynamics with impulsive antiretroviral drug effects.
  • Predictors of HIV testing among men who have sex with men in a large Chinese city.
  • Estimating HIV-1 Transmission Routes for Patients With Unknown Risk Histories by Viral Sequence Phylogenetic Analyses.
  • Genomic characterization of two novel HIV-1 unique (CRF01_AE/B) recombinant forms among men who have sex with men in Beijing, China.
  • Willingness to use the oral fluid HIV rapid test among men who have sex with men in Beijing, China.
  • Lower HIV Risk Among Circumcised Men Who Have Sex With Men in China: Interaction With Anal Sex Role in a Cross-Sectional Study.
  • The rapidly expanding CRF01_AE epidemic in China is driven by multiple lineages of HIV-1 viruses introduced in the 1990s.
  • Predictors of HIV and syphilis among men who have sex with men in a Chinese metropolitan city: comparison of risks among students and non-students.
  • Meta-Analysis of Interventions for Reducing Number of Sexual Partners and Drug and Alcohol Abuse among People Living with HIV/AIDS.
  • Modeling the impact on HIV incidence of combination prevention strategies among men who have sex with men in Beijing, China.
  • Effectiveness of HIV risk reduction interventions among men who have sex with men in China: a systematic review and meta-analysis.
  • Threshold virus dynamics with impulsive antiretroviral drug effects
  • Are Low- and Middle-Income Countries Repeating Mistakes Made by High-Income Countries in the Control of HIV for Men who have Sex with Men?
  • The Complex Interaction Between Methamphetamine Abuse and HIV-1 Pathogenesis.
  • Qualitative Assessment of Barriers and Facilitators of Access to HIV Testing Among Men Who Have Sex with Men in China.
  • Sexual risk reduction for HIV-infected persons: a meta-analytic review of "positive prevention" randomized clinical trials.
  • How to use: Click on a object to move its position. Double click to open its homepage. Right click to preview its contents.

    Download the RDF metadata as:   json-ld nt turtle xml License info


    36 TRIPLES      17 PREDICATES      37 URIs      9 LITERALS

    Subject Predicate Object
    1 grants:63ebf4896c58e07d0f5e35ac070931da sg:abstract DESCRIPTION (provided by applicant): There is no proven effective prevention intervention specifically for men who have sex with men (MSM) population. Bundling partial measures and optimize combinations of interventions may have a substantial impact on HIV seroincidence. The goal of this study is to develop and pilot test a package of Test and Link-to-Care (TLC)-based interventions for preparation of future community-level randomized clinical trial. The specific aims are: (1) To conduct a systematic review of the literature and mathematical modeling to guide the selection of HIV prevention interventions for MSM in China; (2) To conduct a pilot study to evaluate the feasibility, acceptability and initial efficacy of a multi-component TLC intervention packages among MSM in China; and (3) To refine and finalize menu-driven HIV prevention packages and design a multi-site randomized clinical trial in 12 Chinese cities to evaluate its impact on HIV seroincidence among Chinese MSM. As a team of an expert network of American and Chinese researchers and community members with rich knowledge in the subject domains and substantial experience in China, we will develop a culturally competent and potentially effective intervention packages for Chinese MSM at the end of this project. The rapid rise of HIV epidemic among Chinese MSM and the comprehensive disease prevention networks in China provide unique environment for conducting a large scale community-based clinical trial.
    2 sg:endYear 2017
    3 sg:fundingAmount 2537047.0
    4 sg:fundingCurrency USD
    5 sg:hasContribution contributions:95ba82ce1ab33b73018e500989afae1c
    6 contributions:b8f8f6c905835cb4e7a60e9ec99e2872
    7 sg:hasFieldOfResearchCode anzsrc-for:11
    8 anzsrc-for:1117
    9 sg:hasFundedPublication articles:0d2df49111c8c4861307f7309d8cad20
    10 articles:11a97665117228e0b1d85c3894c7641a
    11 articles:13c7539da90bbf80deb04638546e015a
    12 articles:155e13895dfca824d347b341e11304a2
    13 articles:282ec31b9a2eb93de930ccbbd11d8693
    14 articles:333498d5b6c061e2540022fb247e6d8e
    15 articles:522e4411f34740923d2d8eaf8373cced
    16 articles:63b2b40c6a29b6cf2c7eca7f8fa9bc7e
    17 articles:6569f0532cc3675570a8abe8697477f7
    18 articles:6fdd9e574b3d2a6ddc82a523747a56e1
    19 articles:8171f06d0e8facd8b5e37695cc4b8f04
    20 articles:b26d4b9ea69c206d2258bd3a321964a4
    21 articles:bccb4d086af90db520864637def3d225
    22 articles:bd0ccaccb7c66db3274b2766a7f9b1dd
    23 articles:cfb3a4806ca5cd2bbe55b8d60d7207ec
    24 articles:d0f28c1499d7d245cf2bc5391c559de3
    25 articles:e7700cf4827b91014e460c969ce1a307
    26 articles:f7b202dd024c9e9f198db888784a299c
    27 sg:hasFundingOrganization grid-institutes:grid.419681.3
    28 sg:hasRecipientOrganization grid-institutes:grid.412807.8
    29 sg:language English
    30 sg:license http://scigraph.springernature.com/explorer/license/
    31 sg:scigraphId 63ebf4896c58e07d0f5e35ac070931da
    32 sg:startYear 2011
    33 sg:title Multi-component HIV Intervention Packages for Chinese MSM
    34 sg:webpage http://projectreporter.nih.gov/project_info_description.cfm?aid=9254800
    35 rdf:type sg:Grant
    36 rdfs:label Grant: Multi-component HIV Intervention Packages for Chinese MSM
    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular JSON format for linked data.

    curl -H 'Accept: application/ld+json' 'http://scigraph.springernature.com/things/grants/63ebf4896c58e07d0f5e35ac070931da'

    N-Triples is a line-based linked data format ideal for batch operations .

    curl -H 'Accept: application/n-triples' 'http://scigraph.springernature.com/things/grants/63ebf4896c58e07d0f5e35ac070931da'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'http://scigraph.springernature.com/things/grants/63ebf4896c58e07d0f5e35ac070931da'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'http://scigraph.springernature.com/things/grants/63ebf4896c58e07d0f5e35ac070931da'






    Preview window. Press ESC to close (or click here)


    ...