COPYRIGHT YEAR

2013

AUTHORS

Victor Y. Fujimoto, Hakan Cakmak, Heather G. Huddleston

TITLE

Reproductive and Assisted Reproductive Technology (ART) Outcomes in East Asian Women

ABSTRACT

Health disparities research in women’s reproductive health is evolving and racial disparities have emerged in many areas including in assisted reproductive technology (ART) and reproductive aging in Asian women compared to Caucasians. Observed differences in East Asian women may reflect true biologic differences because of genetic background or may result from various environmental exposures, lifestyle factors, cultural factors, access to care, and specifics of treatments once care has been accessed. All of the studies investigating the disparities in ART outcomes between Asian and Caucasian women demonstrated significantly low implantation, clinical pregnancy, and live birthrates in Asian women using autologous eggs. Higher peak estradiol levels during the ovarian stimulation creating glandular–stromal dyssynchrony may be one of the explanations of the worse pregnancy outcomes in Asian women. Later age of natural menopause and lower prevalence of premature ovarian failure have been reported in some East Asian populations compared to Caucasians. There are still major knowledge gaps in our understanding of these racial and ethnic disparities in East Asian women. Further research to improve our understanding of the source of these disparities is critical to optimizing the delivery of reproductive care across our increasingly diverse society.

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21 TRIPLES      19 PREDICATES      22 URIs      12 LITERALS

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1 book-chapters:6d1dd3c8e3ae7c1484f7c4d19a02d1ea sg:abstract Abstract Health disparities research in women’s reproductive health is evolving and racial disparities have emerged in many areas including in assisted reproductive technology (ART) and reproductive aging in Asian women compared to Caucasians. Observed differences in East Asian women may reflect true biologic differences because of genetic background or may result from various environmental exposures, lifestyle factors, cultural factors, access to care, and specifics of treatments once care has been accessed. All of the studies investigating the disparities in ART outcomes between Asian and Caucasian women demonstrated significantly low implantation, clinical pregnancy, and live birthrates in Asian women using autologous eggs. Higher peak estradiol levels during the ovarian stimulation creating glandular–stromal dyssynchrony may be one of the explanations of the worse pregnancy outcomes in Asian women. Later age of natural menopause and lower prevalence of premature ovarian failure have been reported in some East Asian populations compared to Caucasians. There are still major knowledge gaps in our understanding of these racial and ethnic disparities in East Asian women. Further research to improve our understanding of the source of these disparities is critical to optimizing the delivery of reproductive care across our increasingly diverse society.
2 sg:chapterNumber Chapter 7
3 sg:copyrightHolder Springer Science+Business Media New York
4 sg:copyrightYear 2013
5 sg:ddsId b978-1-4614-7548-4_7
6 sg:doi 10.1007/978-1-4614-7548-4_7
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13 sg:language En
14 sg:license http://scigraph.springernature.com/explorer/license/
15 sg:pageFirst 95
16 sg:pageLast 104
17 sg:scigraphId 6d1dd3c8e3ae7c1484f7c4d19a02d1ea
18 sg:title Reproductive and Assisted Reproductive Technology (ART) Outcomes in East Asian Women
19 sg:webpage https://link.springer.com/10.1007/978-1-4614-7548-4_7
20 rdf:type sg:BookChapter
21 rdfs:label BookChapter: Reproductive and Assisted Reproductive Technology (ART) Outcomes in East Asian Women
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