PUBLICATION DATE

1990-12

TITLE

Primary progressive aphasia. Longitudinal course, neuropsychological profile, and language features.

ISSUE

12

VOLUME

47

ISSN (print)

N/A

ISSN (electronic)

N/A

ABSTRACT

Four patients with the clinical syndrome of primary progressive aphasia and a nonfluent aphasia profile were followed up over a period of 3 to 5 years. Extensive neuropsychological data for three patients revealed a progressive, quantitative decline of language with relative stability of memory, visuospatial skills, and reasoning. Comportment and most activities of daily living were preserved even when speech was unintelligible. Although several aphasia types may be associated with primary progressive aphasia, a nonfluent aphasia profile and phonemic paraphasic errors are most useful in differentiating it from the much more common clinical syndrome, "probable Alzheimer's disease." The clinicopathological correlates of probable Alzheimer's disease differ from those associated with primary progressive aphasia. Therefore, the clinical distinction between the two syndromes may be important for predicting the underlying pathophysiologic changes during the life of the patient.

Related objects

JOURNAL BRAND

N/A (note: articles not published by Springer Nature have limited metadata)


FROM GRANT

  • Massachusetts Alzheimer's Disease Research Center
  • How to use: Click on a object to move its position. Double click to open its homepage. Right click to preview its contents.

    Download the RDF metadata as:   json-ld nt turtle xml License info


    14 TRIPLES      14 PREDICATES      15 URIs      10 LITERALS

    Subject Predicate Object
    1 articles:77b12d5384e0fac42891698958aeb9aa sg:abstract Four patients with the clinical syndrome of primary progressive aphasia and a nonfluent aphasia profile were followed up over a period of 3 to 5 years. Extensive neuropsychological data for three patients revealed a progressive, quantitative decline of language with relative stability of memory, visuospatial skills, and reasoning. Comportment and most activities of daily living were preserved even when speech was unintelligible. Although several aphasia types may be associated with primary progressive aphasia, a nonfluent aphasia profile and phonemic paraphasic errors are most useful in differentiating it from the much more common clinical syndrome, "probable Alzheimer's disease." The clinicopathological correlates of probable Alzheimer's disease differ from those associated with primary progressive aphasia. Therefore, the clinical distinction between the two syndromes may be important for predicting the underlying pathophysiologic changes during the life of the patient.
    2 sg:doi 10.1001/archneur.1990.00530120075013
    3 sg:doiLink http://dx.doi.org/10.1001/archneur.1990.00530120075013
    4 sg:isFundedPublicationOf grants:78496b69d85175a42cfa7d4206d99cc7
    5 sg:issue 12
    6 sg:language English
    7 sg:license http://scigraph.springernature.com/explorer/license/
    8 sg:publicationYear 1990
    9 sg:publicationYearMonth 1990-12
    10 sg:scigraphId 77b12d5384e0fac42891698958aeb9aa
    11 sg:title Primary progressive aphasia. Longitudinal course, neuropsychological profile, and language features.
    12 sg:volume 47
    13 rdf:type sg:Article
    14 rdfs:label Article: Primary progressive aphasia. Longitudinal course, neuropsychological profile, and language features.
    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular JSON format for linked data.

    curl -H 'Accept: application/ld+json' 'http://scigraph.springernature.com/things/articles/77b12d5384e0fac42891698958aeb9aa'

    N-Triples is a line-based linked data format ideal for batch operations .

    curl -H 'Accept: application/n-triples' 'http://scigraph.springernature.com/things/articles/77b12d5384e0fac42891698958aeb9aa'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'http://scigraph.springernature.com/things/articles/77b12d5384e0fac42891698958aeb9aa'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'http://scigraph.springernature.com/things/articles/77b12d5384e0fac42891698958aeb9aa'






    Preview window. Press ESC to close (or click here)


    ...