Agios Pharmaceuticals (United States)


Ontology type: grid:Company  | foaf:Organization     


Organization Info

NAME

Agios Pharmaceuticals (United States)

ADDRESS

http://www.grid.ac/institutes/grid.427815.d/address-0

Publications in SciGraph latest 20 shown

  • 2019-12 A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition in NATURE COMMUNICATIONS
  • 2019-12 Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase in NATURE COMMUNICATIONS
  • 2019-04-09 Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia. in LEUKEMIA
  • 2019-04 Characterization and phase I study of CLR457, an orally bioavailable pan-class I PI3-kinase inhibitor in INVESTIGATIONAL NEW DRUGS
  • 2019-02-13 Pharmacokinetics, absorption, metabolism, and excretion of [14C]ivosidenib (AG-120) in healthy male subjects in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2018-09 Olipudase alfa for treatment of acid sphingomyelinase deficiency (ASMD): safety and efficacy in adults treated for 30 months in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2018-08 Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate in NATURE MEDICINE
  • 2018-08 Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib in NATURE MEDICINE
  • 2018-07 Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations in NATURE
  • 2018-06-08 Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemia in LEUKEMIA
  • 2018-04 Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis in NATURE
  • 2017-08 Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism in NATURE
  • 2017-07 mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer in NATURE
  • 2017-06 A pharmacogenomic approach validates AG-221 as an effective and on-target therapy in IDH2 mutant AML in LEUKEMIA
  • 2017-06 The mitochondrial respiratory chain is essential for haematopoietic stem cell function in NATURE CELL BIOLOGY
  • 2017-03 US immigration order strikes against biotech in NATURE BIOTECHNOLOGY
  • 2016-11 A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model in JOURNAL OF INHERITED METABOLIC DISEASE
  • 2016 Bayesian Frailty Models for Multi-State Survival Data in STATISTICAL APPLICATIONS FROM CLINICAL TRIALS AND PERSONALIZED MEDICINE TO FINANCE AND BUSINESS ANALYTICS
  • 2015-08 ESKAPEing the labyrinth of antibacterial discovery in NATURE REVIEWS DRUG DISCOVERY
  • 2015 Design Strategies for Computational Fragment-Based Drug Design in FRAGMENT-BASED METHODS IN DRUG DISCOVERY
  • JSON-LD is the canonical representation for SciGraph data.

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        "grid:cityName": [
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            "@value": "Cambridge"
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        "grid:countryCode": [
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        "grid:countryName": [
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        "id": "http://www.grid.ac/institutes/grid.427815.d/address-0", 
        "sdDataset": "grid", 
        "type": [
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    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

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    This table displays all metadata directly associated to this object as RDF triples.

    13 TRIPLES      6 PREDICATES      7 URIs      3 LITERALS

    Subject Predicate Object
    1 grid-institutes:grid.427815.d sgo:sdDataset grid
    2 grid:hasAddress grid-institutes:grid.427815.d/address-0
    3 grid:id grid.427815.d
    4 rdf:type grid:Company
    5 foaf:Organization
    6 rdfs:label Agios Pharmaceuticals (United States)
    7 skos:prefLabel Agios Pharmaceuticals (United States)
    8 grid-institutes:grid.427815.d/address-0 sgo:sdDataset grid
    9 grid:cityName Cambridge
    10 grid:countryCode US
    11 grid:countryName United States
    12 grid:hasGeonamesCity http://sws.geonames.org/4931972/
    13 rdf:type grid:Address
     




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