Trabectedin therapy as an emerging treatment strategy for recurrent platinum-sensitive ovarian cancer View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-01

AUTHORS

José Antonio López-Guerrero, Ignacio Romero, Andrés Poveda

ABSTRACT

Epithelial ovarian cancer (OC) is a common gynecologic malignancy in women. The standard treatment for OC is maximal cytoreductive surgical debulking followed by platinum-based chemotherapy. Despite the high response rate to primary therapy, approximately 85% of patients will develop recurrent ovarian cancer (ROC). This review identifies the clinical use of trabectedin in the treatment algorithm for ROC, with specific emphasis on platinum-sensitive ROC, for which trabectedin in combination with pegylated liposomal doxorubicin has been approved as a treatment protocol. The main mechanisms of action of trabectedin at the cellular level and in the tumor microenvironment is also discussed as bases for identifying biomarkers for selecting patients who may largely benefit from trabectedin-based therapies. More... »

PAGES

41-49

Identifiers

URI

http://scigraph.springernature.com/pub.10.5732/cjc.014.10278

DOI

http://dx.doi.org/10.5732/cjc.014.10278

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009933648

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25556617


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antineoplastic Agents, Alkylating", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma, Ovarian Epithelial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Clinical Trials as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Damage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dioxoles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Doxorubicin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Recurrence, Local", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasms, Glandular and Epithelial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ovarian Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polyethylene Glycols", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tetrahydroisoquinolines", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Trabectedin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Microenvironment", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda", 
          "id": "https://www.grid.ac/institutes/grid.418082.7", 
          "name": [
            "Laboratory of Molecular Biology, Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda, C/Prof. Beltr\u00e1n B\u00e1guena 8-11, 46009, Valencia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "L\u00f3pez-Guerrero", 
        "givenName": "Jos\u00e9 Antonio", 
        "id": "sg:person.01263071510.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263071510.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda", 
          "id": "https://www.grid.ac/institutes/grid.418082.7", 
          "name": [
            "Clinical Area of Gynecological Cancer, Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda, C/Prof. Beltr\u00e1n B\u00e1guena 8-11, 46009, Valencia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Romero", 
        "givenName": "Ignacio", 
        "id": "sg:person.01320175666.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320175666.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda", 
          "id": "https://www.grid.ac/institutes/grid.418082.7", 
          "name": [
            "Clinical Area of Gynecological Cancer, Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda, C/Prof. Beltr\u00e1n B\u00e1guena 8-11, 46009, Valencia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Poveda", 
        "givenName": "Andr\u00e9s", 
        "id": "sg:person.01372601517.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372601517.89"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1093/annonc/mdq352", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000187190"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bcp.2005.04.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000627281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bcp.2005.04.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000627281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature10166", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000736346", 
          "https://doi.org/10.1038/nature10166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccr.2013.01.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001052526"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-06-1269", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002322303"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdp198", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002901520"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdp198", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002901520"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-06-0179", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003315498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11912-011-0199-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005460744", 
          "https://doi.org/10.1007/s11912-011-0199-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/b808331m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005759510"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2009.25.7519", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005951884"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2009.25.4037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005970596"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ygyno.2013.05.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006197768"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ygyno.2013.05.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006197768"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.2014.149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006338022", 
          "https://doi.org/10.1038/bjc.2014.149"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ctrv.2013.08.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008721264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.critrevonc.2006.03.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010661672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.21276", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011674754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.21276", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011674754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6604088", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012158406", 
          "https://doi.org/10.1038/sj.bjc.6604088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chembiol.2011.06.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014113852"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-012-0435-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014669959", 
          "https://doi.org/10.1007/s12032-012-0435-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mds358", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014749707"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.2012.20", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015078352"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0020-7292(06)60033-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016991733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-04-4037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020749527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/igc.0b013e31821b2568", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021333604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/igc.0b013e31821b2568", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021333604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/igc.0b013e31821b2568", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021333604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-10-0263", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022147280"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0304-3835(01)00690-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022266682"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.2011.1456", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024375837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10637-010-9559-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024998258", 
          "https://doi.org/10.1007/s10637-010-9559-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-011-9979-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025128313", 
          "https://doi.org/10.1007/s12032-011-9979-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-07-0192", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025626642"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2012.04.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026286077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2012.04.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026286077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10637-011-9662-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027026346", 
          "https://doi.org/10.1007/s10637-011-9662-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10637-011-9662-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027026346", 
          "https://doi.org/10.1007/s10637-011-9662-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35077232", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027480321", 
          "https://doi.org/10.1038/35077232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35077232", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027480321", 
          "https://doi.org/10.1038/35077232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ygyno.2013.10.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028240747"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1634/theoncologist.7-suppl_5-20", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028803504"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc2167", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030663176", 
          "https://doi.org/10.1038/nrc2167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/ijms14010640", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033173422"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0959-8049(00)00357-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033499301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2008.01.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033544093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2005.09.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035039610"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm3047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035058324", 
          "https://doi.org/10.1038/nrm3047"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(03)13718-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035404465"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.critrevonc.2007.04.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035920952"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00280-011-1614-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037249516", 
          "https://doi.org/10.1007/s00280-011-1614-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc3185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038857782", 
          "https://doi.org/10.1038/nrc3185"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3322/caac.21208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041182772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1457", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042257134", 
          "https://doi.org/10.1038/nrc1457"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1457", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042257134", 
          "https://doi.org/10.1038/nrc1457"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-09-2335", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046876066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/onc.2013.462", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047744564", 
          "https://doi.org/10.1038/onc.2013.462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/onc.2013.462", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047744564", 
          "https://doi.org/10.1038/onc.2013.462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/igc.0b013e31821bb8aa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048008691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/igc.0b013e31821bb8aa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048008691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/igc.0b013e31821bb8aa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048008691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc2644", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048437103", 
          "https://doi.org/10.1038/nrc2644"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc2644", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048437103", 
          "https://doi.org/10.1038/nrc2644"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1097-0215(19960611)66:6<779::aid-ijc12>3.0.co;2-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049846622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.1221", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051122048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0609877104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051204279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/91008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052456061", 
          "https://doi.org/10.1038/91008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc3144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053036406", 
          "https://doi.org/10.1038/nrc3144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi960306b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055211722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi960306b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055211722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm990241l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055959485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm990241l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055959485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/igc.0b013e3181c104fa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1061838171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/igc.0b013e3181c104fa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1061838171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/igc.0b013e3181c104fa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1061838171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/igc.0b013e3181c104fa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1061838171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075116270", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076575070", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3727/0965040042707925", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1076997786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdu338.12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083556771"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-01", 
    "datePublishedReg": "2015-01-01", 
    "description": "Epithelial ovarian cancer (OC) is a common gynecologic malignancy in women. The standard treatment for OC is maximal cytoreductive surgical debulking followed by platinum-based chemotherapy. Despite the high response rate to primary therapy, approximately 85% of patients will develop recurrent ovarian cancer (ROC). This review identifies the clinical use of trabectedin in the treatment algorithm for ROC, with specific emphasis on platinum-sensitive ROC, for which trabectedin in combination with pegylated liposomal doxorubicin has been approved as a treatment protocol. The main mechanisms of action of trabectedin at the cellular level and in the tumor microenvironment is also discussed as bases for identifying biomarkers for selecting patients who may largely benefit from trabectedin-based therapies. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.5732/cjc.014.10278", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1041144", 
        "issn": [
          "1000-467X", 
          "2523-3548"
        ], 
        "name": "Cancer Communications", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "34"
      }
    ], 
    "name": "Trabectedin therapy as an emerging treatment strategy for recurrent platinum-sensitive ovarian cancer", 
    "pagination": "41-49", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "2f52a742eb8aaf658a24a346809b06dc1da64926cc71aa95b33dde0979588f29"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25556617"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101498232"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.5732/cjc.014.10278"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1009933648"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.5732/cjc.014.10278", 
      "https://app.dimensions.ai/details/publication/pub.1009933648"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:41", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000346_0000000346/records_99843_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.5732%2Fcjc.014.10278"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.5732/cjc.014.10278'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.5732/cjc.014.10278'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.5732/cjc.014.10278'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.5732/cjc.014.10278'


 

This table displays all metadata directly associated to this object as RDF triples.

349 TRIPLES      21 PREDICATES      107 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.5732/cjc.014.10278 schema:about N0842585a9c9444b5b4f78b82643e1ed5
2 N2a6436b693a44ae6a5fc94f0d1504b92
3 N2f637e5488bb40db85521464ab72e5e4
4 N4656c7803b8142abbf08876816179daa
5 N4bf3656d7ccb429da0567329b0730d40
6 N535f72e1970c4e3aafaf4244cfe722aa
7 N6281670003684cdfa2134ca8dc6906da
8 N92a303f1546f47a2868ed491724417e7
9 Na1ecf5acf72f44b2a45b5c54896ea7bc
10 Na735d0b10bcd4db98663436bca9052fa
11 Nae6eab736f7940309a9d2a462a0d8f8c
12 Nb2b5fac81c5244fb8d36a48cc31efaf6
13 Ne66f566eb3134390a518ed42aaf83b7c
14 Nf11c00e4923d4f8ebcc08d0bf1f256d8
15 Nf151dc8d80bc4ad38185e94dddc14e51
16 anzsrc-for:11
17 anzsrc-for:1112
18 schema:author Ncb2283aed9ea4c6cabebb1099cafc4f1
19 schema:citation sg:pub.10.1007/s00280-011-1614-z
20 sg:pub.10.1007/s10637-010-9559-3
21 sg:pub.10.1007/s10637-011-9662-0
22 sg:pub.10.1007/s11912-011-0199-3
23 sg:pub.10.1007/s12032-011-9979-8
24 sg:pub.10.1007/s12032-012-0435-1
25 sg:pub.10.1038/35077232
26 sg:pub.10.1038/91008
27 sg:pub.10.1038/bjc.2014.149
28 sg:pub.10.1038/nature10166
29 sg:pub.10.1038/nrc1457
30 sg:pub.10.1038/nrc2167
31 sg:pub.10.1038/nrc2644
32 sg:pub.10.1038/nrc3144
33 sg:pub.10.1038/nrc3185
34 sg:pub.10.1038/nrm3047
35 sg:pub.10.1038/onc.2013.462
36 sg:pub.10.1038/sj.bjc.6604088
37 https://app.dimensions.ai/details/publication/pub.1075116270
38 https://app.dimensions.ai/details/publication/pub.1076575070
39 https://doi.org/10.1001/jama.2011.1456
40 https://doi.org/10.1001/jama.2012.20
41 https://doi.org/10.1002/(sici)1097-0215(19960611)66:6<779::aid-ijc12>3.0.co;2-z
42 https://doi.org/10.1002/cncr.21276
43 https://doi.org/10.1002/ijc.1221
44 https://doi.org/10.1016/j.bcp.2005.04.013
45 https://doi.org/10.1016/j.ccr.2013.01.008
46 https://doi.org/10.1016/j.chembiol.2011.06.007
47 https://doi.org/10.1016/j.critrevonc.2006.03.004
48 https://doi.org/10.1016/j.critrevonc.2007.04.004
49 https://doi.org/10.1016/j.ctrv.2013.08.001
50 https://doi.org/10.1016/j.ejca.2008.01.003
51 https://doi.org/10.1016/j.ejca.2012.04.001
52 https://doi.org/10.1016/j.ygyno.2013.05.021
53 https://doi.org/10.1016/j.ygyno.2013.10.032
54 https://doi.org/10.1016/s0020-7292(06)60033-7
55 https://doi.org/10.1016/s0140-6736(03)13718-x
56 https://doi.org/10.1016/s0304-3835(01)00690-5
57 https://doi.org/10.1016/s0959-8049(00)00357-9
58 https://doi.org/10.1021/bi960306b
59 https://doi.org/10.1021/jm990241l
60 https://doi.org/10.1039/b808331m
61 https://doi.org/10.1073/pnas.0609877104
62 https://doi.org/10.1093/annonc/mdp198
63 https://doi.org/10.1093/annonc/mdq352
64 https://doi.org/10.1093/annonc/mds358
65 https://doi.org/10.1093/annonc/mdu338.12
66 https://doi.org/10.1097/igc.0b013e31821b2568
67 https://doi.org/10.1097/igc.0b013e31821bb8aa
68 https://doi.org/10.1111/igc.0b013e3181c104fa
69 https://doi.org/10.1158/0008-5472.can-04-4037
70 https://doi.org/10.1158/0008-5472.can-06-0179
71 https://doi.org/10.1158/0008-5472.can-09-2335
72 https://doi.org/10.1158/1078-0432.ccr-06-1269
73 https://doi.org/10.1158/1535-7163.mct-07-0192
74 https://doi.org/10.1158/1535-7163.mct-10-0263
75 https://doi.org/10.1200/jco.2005.09.032
76 https://doi.org/10.1200/jco.2009.25.4037
77 https://doi.org/10.1200/jco.2009.25.7519
78 https://doi.org/10.1634/theoncologist.7-suppl_5-20
79 https://doi.org/10.3322/caac.21208
80 https://doi.org/10.3390/ijms14010640
81 https://doi.org/10.3727/0965040042707925
82 schema:datePublished 2015-01
83 schema:datePublishedReg 2015-01-01
84 schema:description Epithelial ovarian cancer (OC) is a common gynecologic malignancy in women. The standard treatment for OC is maximal cytoreductive surgical debulking followed by platinum-based chemotherapy. Despite the high response rate to primary therapy, approximately 85% of patients will develop recurrent ovarian cancer (ROC). This review identifies the clinical use of trabectedin in the treatment algorithm for ROC, with specific emphasis on platinum-sensitive ROC, for which trabectedin in combination with pegylated liposomal doxorubicin has been approved as a treatment protocol. The main mechanisms of action of trabectedin at the cellular level and in the tumor microenvironment is also discussed as bases for identifying biomarkers for selecting patients who may largely benefit from trabectedin-based therapies.
85 schema:genre research_article
86 schema:inLanguage en
87 schema:isAccessibleForFree true
88 schema:isPartOf N1db4ebf5c4194c5fa81fe9f2e21a3beb
89 N5b8ba5f8e914460c9b8b91a1f2fe6b02
90 sg:journal.1041144
91 schema:name Trabectedin therapy as an emerging treatment strategy for recurrent platinum-sensitive ovarian cancer
92 schema:pagination 41-49
93 schema:productId N16d89b7348f04de3a77107015eaaaca7
94 N1ec6b9f9f60c4e3fb6aa49522a798d3c
95 N2353f35790f149f6accdcb7d178241e6
96 N34b940c5fa9f4621b9e6ed88fd4d836a
97 N45b3ce0e57214913b3435786d8171b9a
98 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009933648
99 https://doi.org/10.5732/cjc.014.10278
100 schema:sdDatePublished 2019-04-11T09:41
101 schema:sdLicense https://scigraph.springernature.com/explorer/license/
102 schema:sdPublisher N1fcdd412259646dcbe1bb7b46b3d0a59
103 schema:url https://link.springer.com/10.5732%2Fcjc.014.10278
104 sgo:license sg:explorer/license/
105 sgo:sdDataset articles
106 rdf:type schema:ScholarlyArticle
107 N0842585a9c9444b5b4f78b82643e1ed5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Clinical Trials as Topic
109 rdf:type schema:DefinedTerm
110 N16d89b7348f04de3a77107015eaaaca7 schema:name dimensions_id
111 schema:value pub.1009933648
112 rdf:type schema:PropertyValue
113 N1db4ebf5c4194c5fa81fe9f2e21a3beb schema:volumeNumber 34
114 rdf:type schema:PublicationVolume
115 N1ec6b9f9f60c4e3fb6aa49522a798d3c schema:name readcube_id
116 schema:value 2f52a742eb8aaf658a24a346809b06dc1da64926cc71aa95b33dde0979588f29
117 rdf:type schema:PropertyValue
118 N1fcdd412259646dcbe1bb7b46b3d0a59 schema:name Springer Nature - SN SciGraph project
119 rdf:type schema:Organization
120 N2353f35790f149f6accdcb7d178241e6 schema:name pubmed_id
121 schema:value 25556617
122 rdf:type schema:PropertyValue
123 N2a6436b693a44ae6a5fc94f0d1504b92 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Female
125 rdf:type schema:DefinedTerm
126 N2f637e5488bb40db85521464ab72e5e4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Carcinoma, Ovarian Epithelial
128 rdf:type schema:DefinedTerm
129 N34b940c5fa9f4621b9e6ed88fd4d836a schema:name nlm_unique_id
130 schema:value 101498232
131 rdf:type schema:PropertyValue
132 N45b3ce0e57214913b3435786d8171b9a schema:name doi
133 schema:value 10.5732/cjc.014.10278
134 rdf:type schema:PropertyValue
135 N4656c7803b8142abbf08876816179daa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Dioxoles
137 rdf:type schema:DefinedTerm
138 N4bf3656d7ccb429da0567329b0730d40 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Neoplasms, Glandular and Epithelial
140 rdf:type schema:DefinedTerm
141 N535f72e1970c4e3aafaf4244cfe722aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Ovarian Neoplasms
143 rdf:type schema:DefinedTerm
144 N5b8ba5f8e914460c9b8b91a1f2fe6b02 schema:issueNumber 1
145 rdf:type schema:PublicationIssue
146 N6281670003684cdfa2134ca8dc6906da schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Neoplasm Recurrence, Local
148 rdf:type schema:DefinedTerm
149 N92a303f1546f47a2868ed491724417e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Trabectedin
151 rdf:type schema:DefinedTerm
152 Na1ecf5acf72f44b2a45b5c54896ea7bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Humans
154 rdf:type schema:DefinedTerm
155 Na735d0b10bcd4db98663436bca9052fa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Polyethylene Glycols
157 rdf:type schema:DefinedTerm
158 Nae6eab736f7940309a9d2a462a0d8f8c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Antineoplastic Agents, Alkylating
160 rdf:type schema:DefinedTerm
161 Nb2b5fac81c5244fb8d36a48cc31efaf6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Tetrahydroisoquinolines
163 rdf:type schema:DefinedTerm
164 Ncb2283aed9ea4c6cabebb1099cafc4f1 rdf:first sg:person.01263071510.67
165 rdf:rest Nd646e39f6f254adda2d73000cd78d9f3
166 Nd646e39f6f254adda2d73000cd78d9f3 rdf:first sg:person.01320175666.66
167 rdf:rest Nec431bf6b6984ad4abe35e995e12dd42
168 Ne66f566eb3134390a518ed42aaf83b7c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Tumor Microenvironment
170 rdf:type schema:DefinedTerm
171 Nec431bf6b6984ad4abe35e995e12dd42 rdf:first sg:person.01372601517.89
172 rdf:rest rdf:nil
173 Nf11c00e4923d4f8ebcc08d0bf1f256d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name DNA Damage
175 rdf:type schema:DefinedTerm
176 Nf151dc8d80bc4ad38185e94dddc14e51 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Doxorubicin
178 rdf:type schema:DefinedTerm
179 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
180 schema:name Medical and Health Sciences
181 rdf:type schema:DefinedTerm
182 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
183 schema:name Oncology and Carcinogenesis
184 rdf:type schema:DefinedTerm
185 sg:journal.1041144 schema:issn 1000-467X
186 2523-3548
187 schema:name Cancer Communications
188 rdf:type schema:Periodical
189 sg:person.01263071510.67 schema:affiliation https://www.grid.ac/institutes/grid.418082.7
190 schema:familyName López-Guerrero
191 schema:givenName José Antonio
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263071510.67
193 rdf:type schema:Person
194 sg:person.01320175666.66 schema:affiliation https://www.grid.ac/institutes/grid.418082.7
195 schema:familyName Romero
196 schema:givenName Ignacio
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320175666.66
198 rdf:type schema:Person
199 sg:person.01372601517.89 schema:affiliation https://www.grid.ac/institutes/grid.418082.7
200 schema:familyName Poveda
201 schema:givenName Andrés
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372601517.89
203 rdf:type schema:Person
204 sg:pub.10.1007/s00280-011-1614-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1037249516
205 https://doi.org/10.1007/s00280-011-1614-z
206 rdf:type schema:CreativeWork
207 sg:pub.10.1007/s10637-010-9559-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024998258
208 https://doi.org/10.1007/s10637-010-9559-3
209 rdf:type schema:CreativeWork
210 sg:pub.10.1007/s10637-011-9662-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027026346
211 https://doi.org/10.1007/s10637-011-9662-0
212 rdf:type schema:CreativeWork
213 sg:pub.10.1007/s11912-011-0199-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005460744
214 https://doi.org/10.1007/s11912-011-0199-3
215 rdf:type schema:CreativeWork
216 sg:pub.10.1007/s12032-011-9979-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025128313
217 https://doi.org/10.1007/s12032-011-9979-8
218 rdf:type schema:CreativeWork
219 sg:pub.10.1007/s12032-012-0435-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014669959
220 https://doi.org/10.1007/s12032-012-0435-1
221 rdf:type schema:CreativeWork
222 sg:pub.10.1038/35077232 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027480321
223 https://doi.org/10.1038/35077232
224 rdf:type schema:CreativeWork
225 sg:pub.10.1038/91008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052456061
226 https://doi.org/10.1038/91008
227 rdf:type schema:CreativeWork
228 sg:pub.10.1038/bjc.2014.149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006338022
229 https://doi.org/10.1038/bjc.2014.149
230 rdf:type schema:CreativeWork
231 sg:pub.10.1038/nature10166 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000736346
232 https://doi.org/10.1038/nature10166
233 rdf:type schema:CreativeWork
234 sg:pub.10.1038/nrc1457 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042257134
235 https://doi.org/10.1038/nrc1457
236 rdf:type schema:CreativeWork
237 sg:pub.10.1038/nrc2167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030663176
238 https://doi.org/10.1038/nrc2167
239 rdf:type schema:CreativeWork
240 sg:pub.10.1038/nrc2644 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048437103
241 https://doi.org/10.1038/nrc2644
242 rdf:type schema:CreativeWork
243 sg:pub.10.1038/nrc3144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053036406
244 https://doi.org/10.1038/nrc3144
245 rdf:type schema:CreativeWork
246 sg:pub.10.1038/nrc3185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038857782
247 https://doi.org/10.1038/nrc3185
248 rdf:type schema:CreativeWork
249 sg:pub.10.1038/nrm3047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035058324
250 https://doi.org/10.1038/nrm3047
251 rdf:type schema:CreativeWork
252 sg:pub.10.1038/onc.2013.462 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047744564
253 https://doi.org/10.1038/onc.2013.462
254 rdf:type schema:CreativeWork
255 sg:pub.10.1038/sj.bjc.6604088 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012158406
256 https://doi.org/10.1038/sj.bjc.6604088
257 rdf:type schema:CreativeWork
258 https://app.dimensions.ai/details/publication/pub.1075116270 schema:CreativeWork
259 https://app.dimensions.ai/details/publication/pub.1076575070 schema:CreativeWork
260 https://doi.org/10.1001/jama.2011.1456 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024375837
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1001/jama.2012.20 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015078352
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1002/(sici)1097-0215(19960611)66:6<779::aid-ijc12>3.0.co;2-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1049846622
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1002/cncr.21276 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011674754
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1002/ijc.1221 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051122048
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1016/j.bcp.2005.04.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000627281
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1016/j.ccr.2013.01.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001052526
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1016/j.chembiol.2011.06.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014113852
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1016/j.critrevonc.2006.03.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010661672
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1016/j.critrevonc.2007.04.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035920952
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1016/j.ctrv.2013.08.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008721264
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1016/j.ejca.2008.01.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033544093
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1016/j.ejca.2012.04.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026286077
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1016/j.ygyno.2013.05.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006197768
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1016/j.ygyno.2013.10.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028240747
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1016/s0020-7292(06)60033-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016991733
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1016/s0140-6736(03)13718-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1035404465
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1016/s0304-3835(01)00690-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022266682
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1016/s0959-8049(00)00357-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033499301
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1021/bi960306b schema:sameAs https://app.dimensions.ai/details/publication/pub.1055211722
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1021/jm990241l schema:sameAs https://app.dimensions.ai/details/publication/pub.1055959485
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1039/b808331m schema:sameAs https://app.dimensions.ai/details/publication/pub.1005759510
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1073/pnas.0609877104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051204279
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1093/annonc/mdp198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002901520
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1093/annonc/mdq352 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000187190
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1093/annonc/mds358 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014749707
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1093/annonc/mdu338.12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083556771
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1097/igc.0b013e31821b2568 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021333604
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1097/igc.0b013e31821bb8aa schema:sameAs https://app.dimensions.ai/details/publication/pub.1048008691
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1111/igc.0b013e3181c104fa schema:sameAs https://app.dimensions.ai/details/publication/pub.1061838171
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1158/0008-5472.can-04-4037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020749527
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1158/0008-5472.can-06-0179 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003315498
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1158/0008-5472.can-09-2335 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046876066
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1158/1078-0432.ccr-06-1269 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002322303
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1158/1535-7163.mct-07-0192 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025626642
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1158/1535-7163.mct-10-0263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022147280
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1200/jco.2005.09.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035039610
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1200/jco.2009.25.4037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005970596
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1200/jco.2009.25.7519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005951884
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1634/theoncologist.7-suppl_5-20 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028803504
339 rdf:type schema:CreativeWork
340 https://doi.org/10.3322/caac.21208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041182772
341 rdf:type schema:CreativeWork
342 https://doi.org/10.3390/ijms14010640 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033173422
343 rdf:type schema:CreativeWork
344 https://doi.org/10.3727/0965040042707925 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076997786
345 rdf:type schema:CreativeWork
346 https://www.grid.ac/institutes/grid.418082.7 schema:alternateName Fundación Instituto Valenciano de Oncología
347 schema:name Clinical Area of Gynecological Cancer, Fundación Instituto Valenciano de Oncología, C/Prof. Beltrán Báguena 8-11, 46009, Valencia, Spain
348 Laboratory of Molecular Biology, Fundación Instituto Valenciano de Oncología, C/Prof. Beltrán Báguena 8-11, 46009, Valencia, Spain
349 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...