Early environment and behavioral-biochemical response to trifluoperazine in monkeys View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1968-07

AUTHORS

W. F. Angermeier, J. B. Phelps, H. H. Reynolds, R. L. Davis

ABSTRACT

Twenty-four differentially reared male rhesus monkeys were used as Ss in this experiment. For 30 days the animals were injected twice daily with trifluoperazine. The effects of these injections were measured on a match-to-sample task previously learned and on a number of blood biochemical assessments. Results indicated that (1) the drug reduced the sensitivity to shock in a shock-escape match-to-sample task according to degrees of previous environmental stimulation during early rearing; (2) the least affected Ss were the animals reared in strict isolation, animals reared in partial isolation and under normal social conditions were moderately affected, and animals reared in enriched environments were greatly affected; (3) these effects could be interpreted to indicate differential early threshold development in the four rearing groups used in this experiment; and (4) drug injections could be considered “therapeutic” in the same sense that social change was thought to be therapeutic in a previous study. More... »

PAGES

231-232

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.3758/bf03327675

DOI

http://dx.doi.org/10.3758/bf03327675

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000196473


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