Green synthesis of silver nanoparticles using Hyptis suaveolens (L.) Poit leaf extracts, their characterization and cytotoxicity evaluation against PC-3 and ... View Full Text


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Article Info

DATE

2019-03-26

AUTHORS

Satyanarayana Botcha, Subhashini Devi Prattipati

ABSTRACT

The green synthesis of nanoparticles using plant extracts is an efficient eco-friendly approach. The present study is aimed at investigating the green synthesis of silver nanoparticles (AgNPs) using aqueous leaf extract of Hyptis suaveolens and evaluation of their cytotoxicity against cancer cells. The formation of AgNPs upon incubation of AgNO3 with leaf extract was identified by color change (yellow to brown), further confirmed by characteristic UV-visible absorbance peak at 436 nm. The Extended dispersive X-ray spectroscopy in turn confirmed elemental silver content in green synthesized AgNPs (G.S.AgNPs). The scanning and transmission electron microscopy revealed randomly dispersed spherical shaped particles in a size range of 20–80 nm. The X-ray diffraction spectroscopy has shown distinct Bragg diffraction peaks corresponding to the planes of face centered cubic lattice, indicating crystalline nature of G.S.AgNPs. The Dynamic light scattering spectroscopy has shown average size distribution of NPs ranging from 80 to 207 nm, certainly higher as it measures the size of entire complexion of organic capping layer with the nanoparticle. The Zeta potential of G.S.AgNPs in water was found to be −13.7 mV, reflecting their higher stability. Further, the Fourier transform infrared spectroscopy revealed the leaf extract’s phenolic compounds and certain proteins responsible for the biological reduction of Ag+ and stabilization of AgNPs. The MTT assay has shown prominent cytotoxic activity of G.S.AgNPs against PC-3 and MDA-MB 231 cells with IC50 values of 63.16 and 52.49 μg/ml respectively. Overall, the study clearly indicates efficient synthesis of AgNPs, which can have a scope for the application in cancer therapy. More... »

PAGES

1-11

References to SciGraph publications

  • 2018-12. Anti-proliferative and cytotoxic activities of Allium autumnale P. H. Davis (Amaryllidaceae) on human breast cancer cell lines MCF-7 and MDA-MB-231 in BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE
  • 2009-01. Rapid biological synthesis of silver nanoparticles using plant leaf extracts in BIOPROCESS AND BIOSYSTEMS ENGINEERING
  • 2009-01. Synthesis of Silver Nanoparticles Using Callus Extract of Carica papaya — A First Report in JOURNAL OF PLANT BIOCHEMISTRY AND BIOTECHNOLOGY
  • 2017-11. Green synthesis of silver nanoparticles using Azadirachta indica leaf extract and its antimicrobial study in APPLIED NANOSCIENCE
  • 2015-10. First report of biomimetic synthesis of silver nanoparticles using aqueous callus extract of Centella asiatica and their antimicrobial activity in APPLIED NANOSCIENCE
  • 2014-12. Leaf extract mediated green synthesis of silver nanoparticles from widely available Indian plants: synthesis, characterization, antimicrobial property and toxicity analysis in BIORESOURCES AND BIOPROCESSING
  • 2004-09. Nanoparticles produced by laser ablation of solids in liquid environment in APPLIED PHYSICS A
  • 2014-03. Efficient and robust biofabrication of silver nanoparticles by cassia alata leaf extract and their antimicrobial activity in JOURNAL OF NANOSTRUCTURE IN CHEMISTRY
  • 2016-06. Green synthesis of silver nanoparticles using leaf extract of medicinally potent plant Saraca indica: a novel study in APPLIED NANOSCIENCE
  • 2014-03. Effect of Curcuma longa tuber powder extract on size of silver nanoparticles prepared by green method in RESEARCH ON CHEMICAL INTERMEDIATES
  • 2013-06. Coleus aromaticus leaf extract mediated synthesis of silver nanoparticles and its bactericidal activity in APPLIED NANOSCIENCE
  • 2008-03. Biosynthesis of nanoparticles: technological concepts and future applications in JOURNAL OF NANOPARTICLE RESEARCH
  • 2016-03. Characterization of silver nanoparticles by green synthesis method using Pedalium murex leaf extract and their antibacterial activity in APPLIED NANOSCIENCE
  • 1998-03. Multiple parameters for the comprehensive evaluation of the susceptibility of Escherichia coli to the silver ion in BIOMETALS
  • Journal

    TITLE

    Biologia

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    URI

    http://scigraph.springernature.com/pub.10.2478/s11756-019-00222-1

    DOI

    http://dx.doi.org/10.2478/s11756-019-00222-1

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1113003964


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