Step by step towards understanding gold glyconanoparticles as elements of the nanoworld View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-08

AUTHORS

L. Sihelníková, I. Tvaroška

ABSTRACT

Gold glyconanoparticles as elements of the nanoworld belong to a group of particles with diameters not exceeding 100 nm. This size scale makes them conformable to common biomolecules. A gold glyconanoparticle consists of three different parts: the gold core, the linkers, and saccharide ligands. The glycocalyx-like surface of these particles mimics the presentation of carbohydrate epitopes of cell surface glycoconjugates. As a consequence, gold glyconanoparticles provide inimitable tools for probing and manipulating the mechanisms of biological processes based on carbohydrate interactions. Each component of the gold glyconanoparticle has a profound effect on the nanoparticle’s properties. Therefore, in this review, elucidation of the overall behavior and properties of gold glyconanoparticles is based on a step by step (component by component) description of the system. More... »

PAGES

237-255

Identifiers

URI

http://scigraph.springernature.com/pub.10.2478/s11696-007-0029-0

DOI

http://dx.doi.org/10.2478/s11696-007-0029-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018423385


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