Prevalence of Left Ventricular Hypertrophy and Determinants of Left Ventricular Mass in Obese Women View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-03

AUTHORS

Guido Salvetti, Andrea Pucci, Paola Fierabracci, Giovanni Ceccarini, Caterina Palagi, Maria Grazia Delle Donne, Vitantonio Di Bello, Paolo Piaggi, Paolo Vitti, Antonio Salvetti, Aldo Pinchera, Ferruccio Santini

ABSTRACT

BACKGROUND: Obesity is frequently associated with left ventricular hypertrophy (LVH), a condition leading to an increased cardiovascular risk. AIM: The objective of this study was to evaluate the prevalence of LVH in a cohort of obese women, with a main focus on the anthropometric and clinical parameters that are associated with an increased left ventricular mass (LVM). METHODS: The study was performed in 166 obese female patients. LVM was measured by echocardiography. The influence of various parameters on LVM was assessed by multivariate analysis. RESULTS: The prevalence of LVH was drastically different depending on the type of indexed LVM, being 19.9% when the LVM was indexed for body surface area and 72.3% when indexed for height. Age, duration of obesity, weight, waist-to-hip ratio, pulse pressure and hypertension retained an independent direct correlation with the LVM, explaining 39.6% of the overall LVM variability. Among the parameters of the metabolic syndrome, the increase in blood pressure was the main determinant of increased LVM. CONCLUSIONS: By using allometric indexation of LVM for height, the results of our study indicate a high prevalence of LVH in a cohort of obese women. Hypertension, pulse pressure, age, duration of obesity, bodyweight and fat distribution, expressed as waist-to-hip ratio, predict 40% of LVM variation. More... »

PAGES

33-39

References to SciGraph publications

  • 2008-09. Global burden of obesity in 2005 and projections to 2030 in INTERNATIONAL JOURNAL OF OBESITY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.2165/11593700-000000000-00000

    DOI

    http://dx.doi.org/10.2165/11593700-000000000-00000

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1041232818

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22670585


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