Can Patients Diagnosed with Schizophrenia Complete Choice-Based Conjoint Analysis Tasks? View Full Text


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Article Info

DATE

2011-12

AUTHORS

John F. P. Bridges, Elizabeth T. Kinter, Annette Schmeding, Ina Rudolph, Axel Mühlbacher

ABSTRACT

BACKGROUND: Schizophrenia is a severe mental illness associated with hallucinations, delusions, apathy, poor social functioning, and impaired cognition. Researchers and funders have been hesitant to focus efforts on treatment preferences of patients with schizophrenia because of the perceived cognitive burden that research methods, such as conjoint analysis, place on them. OBJECTIVE: The objective of this study was to test if patients diagnosed with schizophrenia were able to complete a choice-based conjoint analysis (often referred to as discrete-choice experiments) and to test if meaningful trade-offs were being made. METHODS: German outpatients diagnosed with schizophrenia were eligible to participate in this study if they were aged 18-65 years, had received treatment for at least 1 year and were not experiencing acute symptoms. Conjoint analysis tasks were based on six attributes, each with two levels, which were identified via a literature review and focus groups. A psychologist in a professional interview facility presented each respondent with the eight tasks with little explanation. All interviews were recorded, transcribed, and analyzed to verify that respondents understood the tasks. Preferences were assessed using logistic regression, with a correction for clustering. RESULTS: We found evidence that the 21 patients diagnosed with schizophrenia participating in the study could complete conjoint analysis tasks in a meaningful way. Patients not only related to the scenarios presented in conjoint tasks, but explicitly stated that they used their own preferences to judge which scenarios were better. Statistical analysis confirmed all hypotheses about the attributes (i.e. all attributes had the expected sign). Having a supportive physician, not feeling slowed, and improvements in stressful situations (p < 0.01) were the most important attributes. CONCLUSIONS: We found that patients diagnosed with schizophrenia can complete conjoint analysis tasks, that they base their decisions on their own preferences, and that patients make trade-offs between attributes. More... »

PAGES

267-275

References to SciGraph publications

  • 2008. Designing Discrete Choice Experiments for Health Care in USING DISCRETE CHOICE EXPERIMENTS TO VALUE HEALTH AND HEALTH CARE
  • 2010-06. Estimating importance weights for the IWQOL-Lite using conjoint analysis in QUALITY OF LIFE RESEARCH
  • 2006-09. Patients’ Preferences for Healthcare System Reforms in Hungary in APPLIED HEALTH ECONOMICS AND HEALTH POLICY
  • 2008-10. Conjoint Analysis at the Individual Patient Level in THE PATIENT - PATIENT-CENTERED OUTCOMES RESEARCH
  • 2006-05. Accounting for Tastes in PHARMACOECONOMICS
  • 2008-08. Conducting Discrete Choice Experiments to Inform Healthcare Decision Making in PHARMACOECONOMICS
  • 2008-10. Things are Looking up Since We Started Listening to Patients in THE PATIENT - PATIENT-CENTERED OUTCOMES RESEARCH
  • 2010-12. Conjoint Analysis Applications in Health — How are Studies being Designed and Reported? in THE PATIENT - PATIENT-CENTERED OUTCOMES RESEARCH
  • 2008-01. The Role of The Patient in Promoting Patient-Centered Outcomes Research in THE PATIENT - PATIENT-CENTERED OUTCOMES RESEARCH
  • 1990-11. Depressive syndromes in schizophrenic patients after discharge from hospital in EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.2165/11589190-000000000-00000

    DOI

    http://dx.doi.org/10.2165/11589190-000000000-00000

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1030717838

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/21995832


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