How Physical Exercise Influences the Establishment of Infections View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-06

AUTHORS

Bente K. Pedersen, Helle Bruunsgaard

ABSTRACT

During exercise, leucocytes are recruited to the blood, and if muscle damage occurs the cytokine level is enhanced. After prolonged, intense exercise the number of lymphocytes in the blood is reduced, and the function of natural killer cells is suppressed; furthermore, secretory immunity is impaired. During this time of immunodepression, often referred to as 'the open window', the host may be more susceptible to micro-organisms bypassing the first line of defence. This is of interest to top athletes who perform frequent severe exercise. Clinical observations regarding an increased risk of infections in top athletes are compatible with this model. However, in those performing regular moderate exercise the immune system will often be temporarily enhanced and this will protect these individuals from infections. More... »

PAGES

393-400

Identifiers

URI

http://scigraph.springernature.com/pub.10.2165/00007256-199519060-00003

DOI

http://dx.doi.org/10.2165/00007256-199519060-00003

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022752630

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7676100


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