Phytochemical composition, biological potential and enzyme inhibition activity of Scandix pecten-veneris L. View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-02

AUTHORS

Abdul Wahab, Syed Aleem Jan, Abdur Rauf, Zia ur Rehman, Zahid Khan, Aftab Ahmed, Fatima Syed, Sher Zaman Safi, Hamayun Khan, Muhammad Imran

ABSTRACT

OBJECTIVE: Scandix pecten-veneris L. is a less studied wild edible herb and is considered an extinct plant species in many parts of the world. This study was designed to evaluate its phytochemical composition and biological potential of S. pecten-veneris L. METHODS: Phytochemicals including alkaloids, flavonoids, polyphenols, and tannins were determined in extracts of S. pecten-veneris. Antioxidant activity was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), while reducing power was tested by ferric reducing/antioxidant power (FRAP) assay. Antimicrobial activity against seven bacterial and four fungal strains was evaluated using agar well diffusion assay. Enzymes inhibition study was performed for urease, phosphodiesterase-I, and catalase-II. RESULTS: S. pecten-veneris showed moderate antiradical activity and reducing potential of hydroxyl radicals to about 20% of the initial value. The antioxidant activity of various extracts of S. pecten-veneris showed a linear correlation with total phenolic contents in the order of water>n-butanol>chloroform>ethyl acetate>methanol extracts. S. pecten-veneris leaves showed the highest inhibitory activity against Staphylococcus aureus while the highest antifungal activity was observed against Candida albicans. The plant extract was most potent against urease enzymes but showed moderate activity against phosphodiestrase-I and carbonic anhydrase-II. CONCLUSIONS: Our data demonstrate that in addition to its culinary uses, S. pecten-veneris has good medicinal potential and hence could be used for treating some specific health ailments. More... »

PAGES

120-129

Identifiers

URI

http://scigraph.springernature.com/pub.10.1631/jzus.b1600443

DOI

http://dx.doi.org/10.1631/jzus.b1600443

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1100837539

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29405040


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N-Triples is a line-based linked data format ideal for batch operations.

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Turtle is a human-readable linked data format.

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1631/jzus.b1600443'


 

This table displays all metadata directly associated to this object as RDF triples.

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