Perfil dos pacientes com manifestações extra-articulares de artrite reumatoide de um serviço ambulatorial em Curitiba, Sul do Brasil View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-10

AUTHORS

Mariana Costa Moura, Paola Tamara Silva Zakszewski, Marília Barreto Gameiro Silva, Thelma Larocca Skare

ABSTRACT

OBJETIVO: Descrever o perfil epidemiológico dos pacientes com manifestações extra-articulares (MEA) de artrite reumatoide (AR) do serviço de referência; relatar a prevalência de MEA e compará-la com dados da literatura; relacionar, se possível, fatores preditores dessas manifestações. PACIENTES E MÉTODOS: Foram revisados 262 prontuários de pacientes com AR, diagnosticados pelos critérios de classificação do American College of Rheumatology (1987), que tiveram consulta médica em 2010. Os dados foram coletados e a análise estatística foi feita por descrições, cálculos matemáticos simples, teste t de Student e qui-quadrado, considerando um nível de significância de 5% (α = 0,05). RESULTADOS: Cento e vinte pacientes (45,8%) apresentaram alguma MEA no curso da doença. Manifestações pulmonares, nódulos reumatoides e Síndrome de Sjögren foram mais prevalentes. Fator reumatoide e anticorpo antipeptídeo cíclico citrulinado foram positivos na maior parte dos pacientes com testes disponíveis. A maioria foi classificada como classe 1 e 2 do Índice Funcional de Steinbrocker. O valor médio do Índice de Atividade da Doença-28 (DAS-28, Disease Activity Score-28) foi de 3,629, e do Questionário de Avaliação de Saúde (HAQ, Health Assessment Questionnaire) foi de 1,12. Evidenciou-se que pacientes com MEA possuem a doença há mais tempo (P < 0,05) e que o tabagismo atual está associado à presença das manifestações (P < 0,05). CONCLUSÕES: A prevalência de pacientes que tiveram MEA ao longo do curso de sua doença foi 45,8%, e é possível correlacionar tabagismo atual e aparecimento de MEA. More... »

PAGES

686-694

Identifiers

URI

http://scigraph.springernature.com/pub.10.1590/s0482-50042012000500004

DOI

http://dx.doi.org/10.1590/s0482-50042012000500004

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046163355


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