Hipertensão arterial e uso de leflunomida em artrite reumatóide View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-08

AUTHORS

Leonardo M. Schmidt, Ana Paula Beckhauser, Liz Vallin, Marilia B. Silva, Thelma L. Skare

ABSTRACT

O aumento de pressão arterial (PA) tem sido descrito em usuários de leflunomida para tratamento de artrite reumatóide (AR). Com o intuito de verificar a existência e a freqüência desse efeito colateral nos pacientes do Hospital Universitário Evangélico de Curitiba (HUEC), procedeu-se ao estudo descrito. Quarenta e um usuários de leflunomida tiveram a aferição da PA feita três vezes antes e três vezes depois do início da leflunomida, utilizando-se o valor médio para cálculos estatísticos. O valor médio de PA sistólica antes do uso da leflunomida foi de 117 mmHg e de 125 mm depois do tratamento (p = 0,0038). O valor médio da PA diastólica antes do uso da leflunomida foi de 76 mm antes e de 80,7 mm depois do tratamento (p = 0,0003). Concluiu-se que existe aumento tanto na pressão sistólica quanto na diastólica dos usuários de leflunomida. More... »

PAGES

261-262

Journal

TITLE

Advances in Rheumatology

ISSUE

4

VOLUME

48

Identifiers

URI

http://scigraph.springernature.com/pub.10.1590/s0482-50042008000400013

DOI

http://dx.doi.org/10.1590/s0482-50042008000400013

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043924465


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