Drug–matrix interactions in nanostructured materials containing fluoxetine using sol-gel titanium oxide as a matrix View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-09-13

AUTHORS

Mayra González, Jacques Rieumont, Francois Figueras, Patricia Quintana

ABSTRACT

Titanium oxide matrix was prepared by sol-gel adding fluoxetine [Prozac (C 17 H 18 NF 3 O)] during the reaction of gelation. This nanostructured material was studied by Fourier transform infrared (FTIR) spectroscopy, N 2 adsorption, and x-ray diffraction to detect the interaction between the drug and the matrix. The complex nature of FTIR signals for the matrix and the drug did not allow observation of the interactions; however, using the density functional theory formalism, two stable complexes are suggested to be formed on the drug–matrix system. Both complexes are formed through H bond interactions involving the amine group in fluoxetine and the hydroxylated sites in titanium xerogel. They were found to be energetically stable and independent of the titanium model core cluster used in the calculations. More... »

PAGES

2871-2876

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1557/jmr.2011.266

DOI

http://dx.doi.org/10.1557/jmr.2011.266

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010908742


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/02", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Physical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/09", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0204", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Condensed Matter Physics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0912", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Materials Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0913", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Mechanical Engineering", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Engineering and Chemical Research Center, C.P. 10600, C. Havana City, Cuba; and Polymer Lab, Institute of Materials Science and Technology, University of Havana, C.P. 10400, C. Havana City, Cuba", 
          "id": "http://www.grid.ac/institutes/grid.412165.5", 
          "name": [
            "Engineering and Chemical Research Center, C.P. 10600, C. Havana City, Cuba; and Polymer Lab, Institute of Materials Science and Technology, University of Havana, C.P. 10400, C. Havana City, Cuba"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gonz\u00e1lez", 
        "givenName": "Mayra", 
        "id": "sg:person.012437752515.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012437752515.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Physical Chemistry, Faculty of Chemistry, University of Havana, C.P. 10600, Havana City, Cuba", 
          "id": "http://www.grid.ac/institutes/grid.412165.5", 
          "name": [
            "Department of Physical Chemistry, Faculty of Chemistry, University of Havana, C.P. 10600, Havana City, Cuba"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rieumont", 
        "givenName": "Jacques", 
        "id": "sg:person.010454574747.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010454574747.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut de Recherche sur la Catalyse et l\u2019Environnement de Lyon, UMR 5256, Villeurbanne, France", 
          "id": "http://www.grid.ac/institutes/grid.462054.1", 
          "name": [
            "Institut de Recherche sur la Catalyse et l\u2019Environnement de Lyon, UMR 5256, Villeurbanne, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Figueras", 
        "givenName": "Francois", 
        "id": "sg:person.010012006365.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010012006365.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Applied Physics, CINVESTAV-IPN, M\u00e9rida, A.P. 73, Cordemex, C.P. 97310, M\u00e9rida, Yucat\u00e1n, M\u00e9xico", 
          "id": "http://www.grid.ac/institutes/grid.512574.0", 
          "name": [
            "Department of Applied Physics, CINVESTAV-IPN, M\u00e9rida, A.P. 73, Cordemex, C.P. 97310, M\u00e9rida, Yucat\u00e1n, M\u00e9xico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Quintana", 
        "givenName": "Patricia", 
        "id": "sg:person.0615663102.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615663102.02"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1023/b:nano.0000034623.33083.71", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044157904", 
          "https://doi.org/10.1023/b:nano.0000034623.33083.71"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00549096", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001801624", 
          "https://doi.org/10.1007/bf00549096"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-09-13", 
    "datePublishedReg": "2011-09-13", 
    "description": "Abstract     \n Titanium oxide matrix was prepared by sol-gel adding fluoxetine [Prozac (C 17 H 18 NF 3 O)] during the reaction of gelation. This nanostructured material was studied by Fourier transform infrared (FTIR) spectroscopy, N 2 adsorption, and x-ray diffraction to detect the interaction between the drug and the matrix. The complex nature of FTIR signals for the matrix and the drug did not allow observation of the interactions; however, using the density functional theory formalism, two stable complexes are suggested to be formed on the drug\u2013matrix system. Both complexes are formed through H bond interactions involving the amine group in fluoxetine and the hydroxylated sites in titanium xerogel. They were found to be energetically stable and independent of the titanium model core cluster used in the calculations. ", 
    "genre": "article", 
    "id": "sg:pub.10.1557/jmr.2011.266", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1357547", 
        "issn": [
          "0884-2914", 
          "2044-5326"
        ], 
        "name": "Journal of Materials Research", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "22", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "26"
      }
    ], 
    "keywords": [
      "sol\u2013gel titanium oxide", 
      "drug-matrix interactions", 
      "H-bond interactions", 
      "X-ray diffraction", 
      "density functional theory formalism", 
      "sol-gel", 
      "bond interactions", 
      "amine groups", 
      "titanium oxide matrix", 
      "Fourier transform", 
      "stable complexes", 
      "FTIR signals", 
      "hydroxylated sites", 
      "oxide matrix", 
      "titanium xerogel", 
      "titanium oxide", 
      "complexes", 
      "xerogels", 
      "adsorption", 
      "theory formalism", 
      "spectroscopy", 
      "gelation", 
      "diffraction", 
      "materials", 
      "interaction", 
      "reaction", 
      "oxide", 
      "matrix", 
      "transform", 
      "calculations", 
      "drugs", 
      "core clusters", 
      "clusters", 
      "nature", 
      "complex nature", 
      "sites", 
      "group", 
      "system", 
      "fluoxetine", 
      "observations", 
      "signals", 
      "formalism", 
      "Abstract"
    ], 
    "name": "Drug\u2013matrix interactions in nanostructured materials containing fluoxetine using sol-gel titanium oxide as a matrix", 
    "pagination": "2871-2876", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1010908742"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1557/jmr.2011.266"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1557/jmr.2011.266", 
      "https://app.dimensions.ai/details/publication/pub.1010908742"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:36", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_529.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1557/jmr.2011.266"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1557/jmr.2011.266'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1557/jmr.2011.266'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1557/jmr.2011.266'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1557/jmr.2011.266'


 

This table displays all metadata directly associated to this object as RDF triples.

149 TRIPLES      21 PREDICATES      72 URIs      59 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1557/jmr.2011.266 schema:about anzsrc-for:02
2 anzsrc-for:0204
3 anzsrc-for:09
4 anzsrc-for:0912
5 anzsrc-for:0913
6 schema:author Nfde8f49a70194608a10c1eb449bf149f
7 schema:citation sg:pub.10.1007/bf00549096
8 sg:pub.10.1023/b:nano.0000034623.33083.71
9 schema:datePublished 2011-09-13
10 schema:datePublishedReg 2011-09-13
11 schema:description Abstract Titanium oxide matrix was prepared by sol-gel adding fluoxetine [Prozac (C 17 H 18 NF 3 O)] during the reaction of gelation. This nanostructured material was studied by Fourier transform infrared (FTIR) spectroscopy, N 2 adsorption, and x-ray diffraction to detect the interaction between the drug and the matrix. The complex nature of FTIR signals for the matrix and the drug did not allow observation of the interactions; however, using the density functional theory formalism, two stable complexes are suggested to be formed on the drug–matrix system. Both complexes are formed through H bond interactions involving the amine group in fluoxetine and the hydroxylated sites in titanium xerogel. They were found to be energetically stable and independent of the titanium model core cluster used in the calculations.
12 schema:genre article
13 schema:isAccessibleForFree false
14 schema:isPartOf N29616a8f2ca14a0aa4d9d7b9e5e89b02
15 Nbdb19c6c9fe64df8ab35539ed9be9950
16 sg:journal.1357547
17 schema:keywords Abstract
18 FTIR signals
19 Fourier transform
20 H-bond interactions
21 X-ray diffraction
22 adsorption
23 amine groups
24 bond interactions
25 calculations
26 clusters
27 complex nature
28 complexes
29 core clusters
30 density functional theory formalism
31 diffraction
32 drug-matrix interactions
33 drugs
34 fluoxetine
35 formalism
36 gelation
37 group
38 hydroxylated sites
39 interaction
40 materials
41 matrix
42 nature
43 observations
44 oxide
45 oxide matrix
46 reaction
47 signals
48 sites
49 sol-gel
50 sol–gel titanium oxide
51 spectroscopy
52 stable complexes
53 system
54 theory formalism
55 titanium oxide
56 titanium oxide matrix
57 titanium xerogel
58 transform
59 xerogels
60 schema:name Drug–matrix interactions in nanostructured materials containing fluoxetine using sol-gel titanium oxide as a matrix
61 schema:pagination 2871-2876
62 schema:productId N43d62325ad534141a468b822098da63e
63 N4a6fcb9bc60d48a2bb023563431787db
64 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010908742
65 https://doi.org/10.1557/jmr.2011.266
66 schema:sdDatePublished 2022-10-01T06:36
67 schema:sdLicense https://scigraph.springernature.com/explorer/license/
68 schema:sdPublisher N5f9141a9bde240c7b902c607d3bd6dc1
69 schema:url https://doi.org/10.1557/jmr.2011.266
70 sgo:license sg:explorer/license/
71 sgo:sdDataset articles
72 rdf:type schema:ScholarlyArticle
73 N29616a8f2ca14a0aa4d9d7b9e5e89b02 schema:volumeNumber 26
74 rdf:type schema:PublicationVolume
75 N2fd59fd951d8485599c46aebb594f5da rdf:first sg:person.010454574747.00
76 rdf:rest N3b45e9414dc542788f950226c7d71562
77 N3b45e9414dc542788f950226c7d71562 rdf:first sg:person.010012006365.31
78 rdf:rest Na6689f291d8c45359bed39366371deb1
79 N43d62325ad534141a468b822098da63e schema:name doi
80 schema:value 10.1557/jmr.2011.266
81 rdf:type schema:PropertyValue
82 N4a6fcb9bc60d48a2bb023563431787db schema:name dimensions_id
83 schema:value pub.1010908742
84 rdf:type schema:PropertyValue
85 N5f9141a9bde240c7b902c607d3bd6dc1 schema:name Springer Nature - SN SciGraph project
86 rdf:type schema:Organization
87 Na6689f291d8c45359bed39366371deb1 rdf:first sg:person.0615663102.02
88 rdf:rest rdf:nil
89 Nbdb19c6c9fe64df8ab35539ed9be9950 schema:issueNumber 22
90 rdf:type schema:PublicationIssue
91 Nfde8f49a70194608a10c1eb449bf149f rdf:first sg:person.012437752515.48
92 rdf:rest N2fd59fd951d8485599c46aebb594f5da
93 anzsrc-for:02 schema:inDefinedTermSet anzsrc-for:
94 schema:name Physical Sciences
95 rdf:type schema:DefinedTerm
96 anzsrc-for:0204 schema:inDefinedTermSet anzsrc-for:
97 schema:name Condensed Matter Physics
98 rdf:type schema:DefinedTerm
99 anzsrc-for:09 schema:inDefinedTermSet anzsrc-for:
100 schema:name Engineering
101 rdf:type schema:DefinedTerm
102 anzsrc-for:0912 schema:inDefinedTermSet anzsrc-for:
103 schema:name Materials Engineering
104 rdf:type schema:DefinedTerm
105 anzsrc-for:0913 schema:inDefinedTermSet anzsrc-for:
106 schema:name Mechanical Engineering
107 rdf:type schema:DefinedTerm
108 sg:journal.1357547 schema:issn 0884-2914
109 2044-5326
110 schema:name Journal of Materials Research
111 schema:publisher Springer Nature
112 rdf:type schema:Periodical
113 sg:person.010012006365.31 schema:affiliation grid-institutes:grid.462054.1
114 schema:familyName Figueras
115 schema:givenName Francois
116 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010012006365.31
117 rdf:type schema:Person
118 sg:person.010454574747.00 schema:affiliation grid-institutes:grid.412165.5
119 schema:familyName Rieumont
120 schema:givenName Jacques
121 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010454574747.00
122 rdf:type schema:Person
123 sg:person.012437752515.48 schema:affiliation grid-institutes:grid.412165.5
124 schema:familyName González
125 schema:givenName Mayra
126 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012437752515.48
127 rdf:type schema:Person
128 sg:person.0615663102.02 schema:affiliation grid-institutes:grid.512574.0
129 schema:familyName Quintana
130 schema:givenName Patricia
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615663102.02
132 rdf:type schema:Person
133 sg:pub.10.1007/bf00549096 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001801624
134 https://doi.org/10.1007/bf00549096
135 rdf:type schema:CreativeWork
136 sg:pub.10.1023/b:nano.0000034623.33083.71 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044157904
137 https://doi.org/10.1023/b:nano.0000034623.33083.71
138 rdf:type schema:CreativeWork
139 grid-institutes:grid.412165.5 schema:alternateName Department of Physical Chemistry, Faculty of Chemistry, University of Havana, C.P. 10600, Havana City, Cuba
140 Engineering and Chemical Research Center, C.P. 10600, C. Havana City, Cuba; and Polymer Lab, Institute of Materials Science and Technology, University of Havana, C.P. 10400, C. Havana City, Cuba
141 schema:name Department of Physical Chemistry, Faculty of Chemistry, University of Havana, C.P. 10600, Havana City, Cuba
142 Engineering and Chemical Research Center, C.P. 10600, C. Havana City, Cuba; and Polymer Lab, Institute of Materials Science and Technology, University of Havana, C.P. 10400, C. Havana City, Cuba
143 rdf:type schema:Organization
144 grid-institutes:grid.462054.1 schema:alternateName Institut de Recherche sur la Catalyse et l’Environnement de Lyon, UMR 5256, Villeurbanne, France
145 schema:name Institut de Recherche sur la Catalyse et l’Environnement de Lyon, UMR 5256, Villeurbanne, France
146 rdf:type schema:Organization
147 grid-institutes:grid.512574.0 schema:alternateName Department of Applied Physics, CINVESTAV-IPN, Mérida, A.P. 73, Cordemex, C.P. 97310, Mérida, Yucatán, México
148 schema:name Department of Applied Physics, CINVESTAV-IPN, Mérida, A.P. 73, Cordemex, C.P. 97310, Mérida, Yucatán, México
149 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...