Granulocytic Sarcoma Presenting with Severe Adenopathy (Cervical Lymph Nodes, Tonsils, and Adenoids) in a Child with Juvenile Myelomonocytic Leukemia and ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-08-01

AUTHORS

Toshihiko Imamura, Satoshi Matsuo, Takao Yoshihara, Tomohiro Chiyonobu, Kanako Mori, Hiroyuki Ishida, Yasutaka Nishimura, Yasuo Kasubuchi, Mayumi Naya, Akira Morimoto, Shigeyoshi Hibi, Shinsaku Imashuku

ABSTRACT

The occurrence of adenopathy in patients with myelodysplastic syndrome-associated extramedullary myeloid cell tumors has rarely been reported.We describe a 7-year-old girl with juvenile myelomonocytic leukemia who showed the novel chromosomal abnormality t(9;12)(p22;q24.1) and who developed severe adenopathy of the cervical lymph nodes, tonsils, and adenoids that was manifested as granulocytic sarcoma. Following chemotherapy, the patient underwent a conditioning regimen of busulfan, cyclophosphamide, and total body irradiation followed by successful allogeneic bone marrow transplantation from her single HLA locus-mismatched mother at 6 months after her diagnosis. The patient continues to be well and in remission 3 years after stem cell transplantation. More... »

PAGES

186-189

Identifiers

URI

http://scigraph.springernature.com/pub.10.1532/ijh97.04040

DOI

http://dx.doi.org/10.1532/ijh97.04040

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040900405

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15481450


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