Glycemic control in patients with insulinoma View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-10

AUTHORS

Agata Matej, Hanna Bujwid, Jakub Wroński

ABSTRACT

Insulinoma is the most common neuroendocrine tumor of the pancreas. Surgical management of insulinomas is considered to be the only curative method. However, effective glycemic control preoperatively and in unresectable insulinomas remains a significant issue. Hyperinsulinism, occurring as a result of the hormone-secreting tumor, leads to life-threatening hypoglycemia episodes which require urgent medical treatment. This article discusses current management of hypoglycemia in insulinoma patients, including: education and lifestyle modifications, pharmacotherapy (diazoxide, somatostatin analogs, mTOR inhibitor — everolimus), cytoreductive methods and continuous glucose monitoring systems. More... »

PAGES

489-499

References to SciGraph publications

  • 1983-02. Evidence for a therapeutic effect of dl-propranolol in benign and malignant insulinoma: report of three cases in JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
  • 2007-05. Differential Expression of the Five Somatostatin Receptor Subtypes in Human Benign and Malignant Insulinomas – Predominance of Receptor Subtype 4 in ENDOCRINE PATHOLOGY
  • 1978-10. The effect of propranolol on hypoglycaemia in DIABETOLOGIA
  • 2006-08. Recurrent hyperinsulinemic hypoglycemia caused by an insulin-secreting insulinoma in NATURE REVIEWS ENDOCRINOLOGY
  • 2016-08-18. Advances in the diagnosis and treatment of pancreatic neuroendocrine neoplasms in Japan in JOURNAL OF GASTROENTEROLOGY
  • 2013-03-05. Management of malignant insulinoma in CLINICAL AND TRANSLATIONAL ONCOLOGY
  • 2016-09-13. The treatment of hyperinsulinemic hypoglycaemia in adults: an update in JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
  • 1986-08. Diazoxide in the management of patients with insulinoma in WORLD JOURNAL OF SURGERY
  • 2016-04-01. Pasireotide for malignant insulinoma in HORMONES
  • 2005-06-16. Symptomatic control of hypoglycaemia with prednisone in refractory metastatic pancreatic insulinoma in SUPPORTIVE CARE IN CANCER
  • 2014-12-12. Prognostic factors for pancreatic neuroendocrine neoplasms (pNET) and the risk of small non-functioning pNET in JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
  • 2011-08-17. Radioembolization of Symptomatic, Unresectable Neuroendocrine Hepatic Metastases Using Yttrium-90 Microspheres in CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.14310/horm.2002.1706

    DOI

    http://dx.doi.org/10.14310/horm.2002.1706

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1083853806

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28222404


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