Distribution and biotransformation of arsenic species in chicken cardiac and muscle tissues View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-06

AUTHORS

I. Pizarro, M. M. Gómez, P. Fodor, M. A. Palacios, C. Cámara

ABSTRACT

This study evaluated the bioaccumulation and biotransformation of arsenic species in chicken heart and meat tissues. The experimental study was carried out using two sets of samples. In the first one, 10-d-old chickens were exposed to sodium arsenate, using spiked drinking water. These chickens grew normally and were killed after 50 d of arsenic exposure. The second set were edible chickens used as blanks for a parallel study. The total arsenic and arsenic species content in the exposed samples were at least twice those in the normal edible chicken. It has been demonstrated that sodium arsenate is biotransformed to arsenite and an unknown species and its distribution varies among the different cardiac and meat tissues. One important aspect is the capability of the auricle to preconcentrate the most toxic species, arsenite, in the exposed chicken. A nonidentified arsenic species from the edible chicken was detected. Arsenobetaine was also detected in several tissues. This article shows that chicken can be used as a representative animal when considering inorganic arsenic exposure in humans. More... »

PAGES

129-143

Identifiers

URI

http://scigraph.springernature.com/pub.10.1385/bter:99:1-3:129

DOI

http://dx.doi.org/10.1385/bter:99:1-3:129

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006267507

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15235148


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