Altered elemental profile as indicator of homeostatic imbalance in pathogenesis of oral submucous fibrosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-06

AUTHORS

Ranjan Rashmi Paul, Jyotirmoy Chatterjee, Arabinda K. Das, M. Luisa Cervera, Miguel de la Guardia, Keya Chaudhuri

ABSTRACT

Oral submucous fibrosis (OSF) is a potential precancerous condition of the oral cavity and oropharynx. The etiopathogenesis of this complex precancerous condition is still obscure. In addition to deleterious oral habits, malnutrition, and possible genetic predisposition, altered bioelemental status is also likely to play an important role in its pathogenesis. The present study analyzed 68 elements by inductively coupled plasma-mass spectroscopy in oral mucosa of normal and OSF individuals and some interesting alterations in elemental profile in the diseased tissue have been noted, indicating a homeostatic imbalance. These bioelemental alterations leading to homeostatic imbalance might be considered as an important biological event in the pathogenesis of OSF. More... »

PAGES

45-56

Identifiers

URI

http://scigraph.springernature.com/pub.10.1385/bter:87:1-3:045

DOI

http://dx.doi.org/10.1385/bter:87:1-3:045

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048972841

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12117232


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