Automated Protein Identification Using Microcolumn Liquid Chromatography-Tandem Mass Spectrometry View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1999

AUTHORS

John R. Yates , Edwin Carmack , Lara Hays , Andrew J. Link , Jimmy K. Eng

ABSTRACT

The sequencing of complete genomes is providing an enormous resource for understanding the biology of organisms (1). A complete genome sequence, however, will still leave many unanswered questions about the basic biology of the organism. Which open reading frames are authentic genes? What genes express highly abundant proteins in the cell? How well do the observed physical properties of a protein agree with the predictions of the genomic sequence? Which proteins are covalently processed? Analysis of the proteins encoded in the genome or “the proteome” can answer many of these questions, and will help in understanding the physiology of the organism. More... »

PAGES

553-569

Identifiers

URI

http://scigraph.springernature.com/pub.10.1385/1-59259-584-7:553

DOI

http://dx.doi.org/10.1385/1-59259-584-7:553

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053589993

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10027276


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