Extraction of Ancient DNA View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2003-08-01

AUTHORS

John M.S. Bartlett , David Stirling , Wera M. Schmerer

ABSTRACT

The DNA extraction process represents one of the critical stages in the analysis of degraded or ancient DNA. If polymerase chain reaction (PCR) amplification starts from a poor extract containing low template quantities, stochastic variation in the amplification of individual alleles may lead to allelic dropout (1), resulting in a high risk of false-homozygous typing of a heterozygous sample (2). More... »

PAGES

57-62

Identifiers

URI

http://scigraph.springernature.com/pub.10.1385/1-59259-384-4:57

DOI

http://dx.doi.org/10.1385/1-59259-384-4:57

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050420403

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12958484


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