Clinical Trials for Solid Tumors Using Electrochemotherapy View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2000-02-18

AUTHORS

Mark J. Jaroszeski , Richard Heller , Richard Gilbert

ABSTRACT

Chemotherapy is a standard treatment for a wide variety of cancers. However, response rates are usually low. In melanoma, for example, partial response rates range from 20-45 % with complete responses of less than 5% (1-4). The cell membrane can be a significant barrier for agents with an intracellular site of action. The inability to cross the cell membrane and enter the cell could lead to a low response rate. The effectiveness of these agents could be enhanced if combined with a procedure that increases the permeability of the cell membrane. More... »

PAGES

137-56

Book

TITLE

Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery

ISBN

1-59259-080-2

Identifiers

URI

http://scigraph.springernature.com/pub.10.1385/1-59259-080-2:137

DOI

http://dx.doi.org/10.1385/1-59259-080-2:137

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023768564

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21445733


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