Localization of IL-4 and IL-5 mRNA by In Situ Hybridization in Bronchial Biopsies View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2000-06-23

AUTHORS

K. Fan Chung , Ian Adcock , Yutaka Nakamura , Pota Christodoulopoulos , Qutayba Hamid

ABSTRACT

Cytokines are important biochemical mediators essential in initiating and maintaining inflammatory reactions associated with allergic disease in man. Although cytokines can be secreted from a variety of different cell types, considerable attention has been focused on T-lymphocyte-derived cytokines, which have been clearly implicated in the modulation of the immune system. Bronchial asthma is associated with persistent infiltration of the airways with activated CD4(+)T-lymphocytes, as well as other inflammatory cells exhibiting a T-helper type-2 (Th2)-like cytokine profile (1-3). More... »

PAGES

211-25

References to SciGraph publications

Book

TITLE

Asthma

ISBN

1-59259-072-1

Identifiers

URI

http://scigraph.springernature.com/pub.10.1385/1-59259-072-1:211

DOI

http://dx.doi.org/10.1385/1-59259-072-1:211

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010598009

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21312132


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