Immobilization of Enzymes and Proteins on Red Blood Cells View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1996-12-01

AUTHORS

Gordon Bickerstaff , Laura Chiarantini , Mauro Magnani

ABSTRACT

Immobilization of proteins on intact red blood cells (RBCs) can be valuable for several different reasons. In vivo, RBCs carrying specific ligands can be targeted to cells exposing specific antigens, eventually for the delivery of drugs encapsulated in the same RBC (1). Alternatively, RBCs carrying antigens or enzymes on the extracellular surface of their membrane can perform as antigen delivery systems (2) or as bioreactors for the degradation of toxic metabolites (3). In vitro, RBCs carrying proteins can be used as diagnostic reagents in agglutination or hemolytic assays (4). More... »

PAGES

143-152

References to SciGraph publications

  • 1992. Comparison of Uricase-Bound and Uricase-Loaded Erythrocytes as Bioreactors for Uric Acid Degradation in THE USE OF RESEALED ERYTHROCYTES AS CARRIERS AND BIOREACTORS
  • 1992. Targeting of Eythrocytes to Cytotoxic T-Cells in THE USE OF RESEALED ERYTHROCYTES AS CARRIERS AND BIOREACTORS
  • Book

    TITLE

    Immobilization of Enzymes and Cells

    ISBN

    0-89603-386-4

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1385/0-89603-386-4:143

    DOI

    http://dx.doi.org/10.1385/0-89603-386-4:143

    DIMENSIONS

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