Details and Outcomes of Distal Pancreatectomy with Celiac Axis Resection Preserving the Left Gastric Arterial Flow View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-06-18

AUTHORS

Yosuke Inoue, Akio Saiura, Takafumi Sato, Atsushi Oba, Yoshihiro Ono, Yoshihiro Mise, Hiromichi Ito, Yu Takahashi

ABSTRACT

BackgroundTo describe the technical details and efficacy of distal pancreatectomy with celiac axis resection (DP-CAR) and left gastric artery (LGA) flow preservation for pancreatic ductal adenocarcinoma (PDAC).MethodThis single-center, retrospective analysis investigated short- and long-term outcomes of DP-CAR performed on 55 patients with PDAC from 2011 to 2019. Our method included LGA reconstruction after total resection of the CA (rDP-CAR group; 24 patients) or LGA preservation if the tumor invasion was away from its root (pDP-CAR group; 31 patients), a CA-first approach to reduce blood loss during dissection, and conservative drain management with or without jejunal serosal patching at the pancreatic stump.ResultsAmong the study patients, 23 had locally advanced PDAC and 22 had borderline resectable PDAC. Median operation duration was 443 min (248–810), estimated blood loss was 600 mL (150–2280), and incidence of transfusion was 2%. Ischemic complications occurred exclusively in the rDP-CAR group, including two patients with ischemic gastropathy (8%) and three patients with findings of liver ischemia on computed tomography (13%). One patient underwent relaparotomy for stomach perforations, and 19 patients (35%) had pancreatic fistula, including 8 patients who underwent conservative drain placement for more than 3 weeks without specific symptoms. There were no Clavien–Dindo grade 4 or higher postoperative complications. Preoperative therapy showed improved 3-year overall survival rates than without (54% vs. 37%, p = 0.027).ConclusionsUsing the standardized technique, DP-CAR was safely performed with no mortality and acceptable long-term survival. More... »

PAGES

8283-8294

References to SciGraph publications

  • 2019-02-27. Left kidney mobilization technique during radical antegrade modular pancreatosplenectomy (RAMPS) in LANGENBECK'S ARCHIVES OF SURGERY
  • 2017-03-15. Risk factors of postoperative pancreatic fistula in patients after distal pancreatectomy: a systematic review and meta-analysis in SCIENTIFIC REPORTS
  • 2011-09-21. Feasibility of a dual microcatheter-dual interlocking detachable coil technique in preoperative embolization in preparation for distal pancreatectomy with en bloc celiac axis resection for locally advanced pancreatic body cancer in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 2019-07-17. Is hepatic artery coil embolization useful in distal pancreatectomy with en bloc celiac axis resection for locally advanced pancreatic cancer? in WORLD JOURNAL OF SURGICAL ONCOLOGY
  • 2015-08-25. Intraoperative blood loss is not a predictor of prognosis for pancreatic cancer in SURGERY TODAY
  • 2015-10-23. Modified Blumgart Suturing Technique for Remnant Closure After Distal Pancreatectomy: a Propensity Score-Matched Analysis in JOURNAL OF GASTROINTESTINAL SURGERY
  • 2004-04. Ischemic Gastropathy After Distal Pancreatectomy with Celiac Axis Resection in SURGERY TODAY
  • 2019-03-13. Feasibility and safety of distal pancreatectomy with en bloc celiac axis resection (DP-CAR) combined with neoadjuvant therapy for borderline resectable and unresectable pancreatic body/tail cancer in LANGENBECK'S ARCHIVES OF SURGERY
  • 2018-06-28. Ischemic gastropathy after distal pancreatectomy with en bloc celiac axis resection for pancreatic body cancer in LANGENBECK'S ARCHIVES OF SURGERY
  • 1997-08. Distal pancreatectomy withen bloc resection of the celiac artery for carcinoma of the body and tail of the pancreas in JOURNAL OF GASTROINTESTINAL CANCER
  • 2019-01-04. Outcomes and Risk Score for Distal Pancreatectomy with Celiac Axis Resection (DP-CAR): An International Multicenter Analysis in ANNALS OF SURGICAL ONCOLOGY
  • 2012-03-08. Distal Pancreatectomy with En Bloc Celiac Axis Resection for Locally Advanced Pancreatic Adenocarcinoma Following Neoadjuvant Therapy in JOURNAL OF GASTROINTESTINAL SURGERY
  • 2005-02. The significance of intraoperative Doppler ultrasonography in evaluating hepatic arterial flow when assessing the indications for the Appleby procedure for pancreatic body cancer in JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
  • 2019-07-19. Efficacy of Neoadjuvant Chemotherapy in Distal Pancreatectomy with En Bloc Celiac Axis Resection (DP-CAR) for Locally Advanced Pancreatic Cancer in JOURNAL OF GASTROINTESTINAL SURGERY
  • 2014-08-08. Preservation of the Left Gastric Artery on the Basis of Anatomical Features in Patients Undergoing Distal Pancreatectomy with Celiac Axis En-bloc Resection (DP-CAR) in WORLD JOURNAL OF SURGERY
  • 2019-12-09. Early Fistulography Can Predict Whether Biochemical Leakage Develops to Clinically Relevant Postoperative Pancreatic Fistula in WORLD JOURNAL OF SURGERY
  • 2010-10-09. Distal Pancreatectomy With En Bloc Resection of the Celiac Trunk for Extended Pancreatic Tumor Disease: An Interdisciplinary Approach in CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
  • 2016-06-21. Modified Appleby Procedure for Pancreatic Adenocarcinoma: Does Improved Neoadjuvant Therapy Warrant Such an Aggressive Approach? in ANNALS OF SURGICAL ONCOLOGY
  • 2017-01-23. Distal Pancreatectomy with Celiac Axis Resection Combined with Reconstruction of the Left Gastric Artery in JOURNAL OF GASTROINTESTINAL SURGERY
  • 2016-08-05. Distal Pancreatectomy with en Bloc Celiac Axis Resection (Modified Appleby Procedure) for Locally Advanced Pancreatic Body Cancer: A Single-Center Review of 80 Consecutive Patients in ANNALS OF SURGICAL ONCOLOGY
  • 2016-05-19. Distal Pancreatectomy with En Bloc Resection of the Celiac Axis with Preservation or Reconstruction of the Left Gastric Artery in Patients with Pancreatic Body Cancer in WORLD JOURNAL OF SURGERY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1245/s10434-021-10243-3

    DOI

    http://dx.doi.org/10.1245/s10434-021-10243-3

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    PUBMED

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        "description": "BackgroundTo describe the technical details and efficacy of distal pancreatectomy with celiac axis resection (DP-CAR) and left gastric artery (LGA) flow preservation for pancreatic ductal adenocarcinoma (PDAC).MethodThis single-center, retrospective analysis investigated short- and long-term outcomes of DP-CAR performed on 55 patients with PDAC from 2011 to 2019. Our method included LGA reconstruction after total resection of the CA (rDP-CAR group; 24 patients) or LGA preservation if the tumor invasion was away from its root (pDP-CAR group; 31 patients), a CA-first approach to reduce blood loss during dissection, and conservative drain management with or without jejunal serosal patching at the pancreatic stump.ResultsAmong the study patients, 23 had locally advanced PDAC and 22 had borderline resectable PDAC. Median operation duration was 443\u00a0min (248\u2013810), estimated blood loss was 600\u00a0mL (150\u20132280), and incidence of transfusion was 2%. Ischemic complications occurred exclusively in the rDP-CAR group, including two patients with ischemic gastropathy (8%) and three patients with findings of liver ischemia on computed tomography (13%). One patient underwent relaparotomy for stomach perforations, and 19 patients (35%) had pancreatic fistula, including 8 patients who underwent conservative drain placement for more than 3 weeks without specific symptoms. There were no Clavien\u2013Dindo grade 4 or higher postoperative complications. Preoperative therapy showed improved 3-year overall survival rates than without (54% vs. 37%, p\u00a0=\u00a00.027).ConclusionsUsing the standardized technique, DP-CAR was safely performed with no mortality and acceptable long-term survival.", 
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