Survival Impact of Locoregional Treatment of the Primary Tumor in De Novo Metastatic Breast Cancers in a Large Multicentric Cohort ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-02

AUTHORS

Elvire Pons-Tostivint, Youlia Kirova, Amélie Lusque, Mario Campone, Julien Geffrelot, Chafika Mazouni, Audrey Mailliez, David Pasquier, Nicolas Madranges, Nelly Firmin, Agathe Crouzet, Anthony Gonçalves, Clémentine Jankowski, Thibault De La Motte Rouge, Nicolas Pouget, Brigitte de La Lande, Delphine Mouttet-Boizat, Jean-Marc Ferrero, Lionel Uwer, Jean-Christophe Eymard, Marie-Ange Mouret-Reynier, Thierry Petit, Mathieu Robain, Thomas Filleron, Christian Cailliot, Florence Dalenc

ABSTRACT

INTRODUCTION: Improvement in overall survival (OS) by locoregional treatment (LRT) of the primary tumor in de novo metastatic breast cancer (MBC) patients remains controversial. OBJECTIVE: The aim of our study was to evaluate the impact of LRT on OS in a large retrospective cohort of de novo MBC patients, with regard to immunohistochemical characteristics and pattern of metastatic dissemination. METHODS: We conducted a multicentric retrospective study of patients diagnosed with de novo MBC selected from the French Epidemiological Strategy and Medical Economics MBC database (NCT03275311) between 2008 and 2014. Overall, 4276 women were included in the study. LRT comprised either radiotherapy, surgery, or both. RESULTS: LRT was used in 40% of patients. Compared with no LRT, patients who received LRT were younger (p < 0.0001) and were more likely to have only one metastatic site (p < 0.0001) or bone-only metastases (p < 0.0001). LRT was associated with a significantly better OS based on landmark multivariate analysis at 1-year (hazard ratio 0.65, 95% confidence interval 0.55-0.76, p < 0.001). Similar results were observed in all sensitivity analyses, including propensity score matching. In subgroup analysis, LRT was associated with better OS in patients with hormone receptor-positive/human epidermal growth factor receptor 2 (HER2)-negative (61.6 vs. 45.9 months, p < 0.001) and HER2-positive tumors (77.2 vs. 52.6 months, p = 0.008), but not in triple-negative tumors (19 vs. 18.6 months, p = 0.54), and was also associated with a reduction in the risk of death in visceral metastatic patients (p < 0.001). CONCLUSIONS: LRT was associated with a significantly better OS in de novo MBC patients, including patients with visceral involvement at diagnosis; however, LRT did not impact OS in triple-negative MBC. More... »

PAGES

1-10

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1245/s10434-018-6831-9

DOI

http://dx.doi.org/10.1245/s10434-018-6831-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110542256

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30539492


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Medical Oncology, Claudius Regaud Institute, IUCT-Oncopole, Toulouse Cedex 09, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pons-Tostivint", 
        "givenName": "Elvire", 
        "id": "sg:person.014377440763.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014377440763.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute Curie", 
          "id": "https://www.grid.ac/institutes/grid.418596.7", 
          "name": [
            "Department of Radiation Oncology, Curie Institute, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kirova", 
        "givenName": "Youlia", 
        "id": "sg:person.01310327270.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310327270.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Biostatistics, Claudius Regaud Institute, IUCT-Oncopole, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lusque", 
        "givenName": "Am\u00e9lie", 
        "id": "sg:person.01007755571.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007755571.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut de Canc\u00e9rologie de l'Ouest", 
          "id": "https://www.grid.ac/institutes/grid.418191.4", 
          "name": [
            "Department of Medical Oncology, Ren\u00e9 Gauducheau Center, Institut de Canc\u00e9rologie de l\u2019Ouest (ICO), Saint-Herblain, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Campone", 
        "givenName": "Mario", 
        "id": "sg:person.0773526204.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773526204.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, Fran\u00e7ois Baclesse Center, Caen, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Geffrelot", 
        "givenName": "Julien", 
        "id": "sg:person.01054656706.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054656706.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "Department of Surgery, Gustave Roussy Institute, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mazouni", 
        "givenName": "Chafika", 
        "id": "sg:person.01200110513.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01200110513.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Oscar Lambret", 
          "id": "https://www.grid.ac/institutes/grid.452351.4", 
          "name": [
            "Department of Medical Oncology, Oscar Lambret Center, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mailliez", 
        "givenName": "Audrey", 
        "id": "sg:person.0621671544.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621671544.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Oscar Lambret", 
          "id": "https://www.grid.ac/institutes/grid.452351.4", 
          "name": [
            "Department of Radiation Oncology, Oscar Lambret Center, Lille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pasquier", 
        "givenName": "David", 
        "id": "sg:person.01036227135.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036227135.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Bergoni\u00e9", 
          "id": "https://www.grid.ac/institutes/grid.476460.7", 
          "name": [
            "Department of Medical Oncology, Bergoni\u00e9 Institute, Bordeaux, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Madranges", 
        "givenName": "Nicolas", 
        "id": "sg:person.01210731760.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210731760.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "UniCancer Group", 
          "id": "https://www.grid.ac/institutes/grid.418189.d", 
          "name": [
            "Department of Medical Oncology, Institut du Cancer de Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Firmin", 
        "givenName": "Nelly", 
        "id": "sg:person.0603415564.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603415564.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, Henri Becquerel Center, Rouen, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Crouzet", 
        "givenName": "Agathe", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute Paoli-Calmettes", 
          "id": "https://www.grid.ac/institutes/grid.418443.e", 
          "name": [
            "Department of Medical Oncology, Paoli-Calmettes Institute, Marseille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gon\u00e7alves", 
        "givenName": "Anthony", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, Georges-Fran\u00e7ois Leclerc Center, Dijon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jankowski", 
        "givenName": "Cl\u00e9mentine", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medical Oncology, Eug\u00e8ne Marquis Center, Rennes, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "De La Motte Rouge", 
        "givenName": "Thibault", 
        "id": "sg:person.01167112202.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167112202.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute Curie", 
          "id": "https://www.grid.ac/institutes/grid.418596.7", 
          "name": [
            "Department of Surgery, Ren\u00e9 Huguenin Centre, Curie Institute, Saint-Cloud, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pouget", 
        "givenName": "Nicolas", 
        "id": "sg:person.0664373351.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664373351.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute Curie", 
          "id": "https://www.grid.ac/institutes/grid.418596.7", 
          "name": [
            "Department of Radiation Oncology, Ren\u00e9 Huguenin Centre, Curie Institute, Saint-Cloud, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de La Lande", 
        "givenName": "Brigitte", 
        "id": "sg:person.01243677536.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243677536.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute Curie", 
          "id": "https://www.grid.ac/institutes/grid.418596.7", 
          "name": [
            "Department of Surgery, Curie Institute, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mouttet-Boizat", 
        "givenName": "Delphine", 
        "id": "sg:person.015334663367.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015334663367.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medical Oncology, Antoine Lacassagne Cancer Center, Nice, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ferrero", 
        "givenName": "Jean-Marc", 
        "id": "sg:person.01014626365.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014626365.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut de Canc\u00e9rologie de Lorraine", 
          "id": "https://www.grid.ac/institutes/grid.452436.2", 
          "name": [
            "Department of Medical Oncology, Institut de Canc\u00e9rologie de Lorraine, Vandoeuvre-l\u00e8s-Nancy, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uwer", 
        "givenName": "Lionel", 
        "id": "sg:person.01141676130.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141676130.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medical Oncology, Jean Godinot Institute, Reims, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eymard", 
        "givenName": "Jean-Christophe", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medical Oncology, Jean Perrin Center, Clermont-Ferrand, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mouret-Reynier", 
        "givenName": "Marie-Ange", 
        "id": "sg:person.0677500261.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677500261.85"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medical Oncology, Paul Strauss Center, Strasbourg, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Petit", 
        "givenName": "Thierry", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute Curie", 
          "id": "https://www.grid.ac/institutes/grid.418596.7", 
          "name": [
            "Biostatistics Unit, Curie Institute, PSL Research University, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Robain", 
        "givenName": "Mathieu", 
        "id": "sg:person.07727141021.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07727141021.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Biostatistics, Claudius Regaud Institute, IUCT-Oncopole, Toulouse, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Filleron", 
        "givenName": "Thomas", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Research and Development, R&D Unicancer, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cailliot", 
        "givenName": "Christian", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medical Oncology, Claudius Regaud Institute, IUCT-Oncopole, Toulouse Cedex 09, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dalenc", 
        "givenName": "Florence", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1001/jamasurg.2015.4539", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000023771"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181656d32", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001216623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181656d32", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001216623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-016-4080-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004362669", 
          "https://doi.org/10.1007/s10549-016-4080-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-016-4080-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004362669", 
          "https://doi.org/10.1007/s10549-016-4080-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1607303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005496514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.23870", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009180128"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(13)70130-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014610655"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(15)00135-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015580522"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10585-015-9697-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016498846", 
          "https://doi.org/10.1007/s10585-015-9697-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2011.08.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017514898"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-011-1349-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018282929", 
          "https://doi.org/10.1007/s10549-011-1349-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/aso.2006.03.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019710369", 
          "https://doi.org/10.1245/aso.2006.03.033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-008-0085-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020882576", 
          "https://doi.org/10.1245/s10434-008-0085-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5858/arpa.2013-0953-sa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023063099"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-013-2998-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024375344", 
          "https://doi.org/10.1245/s10434-013-2998-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-007-9438-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027122144", 
          "https://doi.org/10.1245/s10434-007-9438-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejso.2009.03.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027586430"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/msy.2002.127544", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032157462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/msy.2002.127544", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032157462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.24873", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033417427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.24873", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033417427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-008-0101-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034009384", 
          "https://doi.org/10.1007/s10549-008-0101-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-008-0101-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034009384", 
          "https://doi.org/10.1007/s10549-008-0101-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035190392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035190392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-011-1648-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035423148", 
          "https://doi.org/10.1007/s10549-011-1648-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2004.08.095", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035477967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.radonc.2010.02.028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036869166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdq220", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037043739"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.19.5396", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039439476"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-012-0310-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043686498", 
          "https://doi.org/10.1007/s12032-012-0310-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-012-0310-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043686498", 
          "https://doi.org/10.1007/s12032-012-0310-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pds.3891", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044027705"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1609709", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045557388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrclinonc.2014.96", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045616176", 
          "https://doi.org/10.1038/nrclinonc.2014.96"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.breast.2016.10.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046767167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-007-9527-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049119926", 
          "https://doi.org/10.1245/s10434-007-9527-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.2015.127", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050007381", 
          "https://doi.org/10.1038/bjc.2015.127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2005.04.2226", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050599872"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.15856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084372974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-018-6494-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104049156", 
          "https://doi.org/10.1245/s10434-018-6494-6"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-02", 
    "datePublishedReg": "2019-02-01", 
    "description": "INTRODUCTION: Improvement in overall survival (OS) by locoregional treatment (LRT) of the primary tumor in de novo metastatic breast cancer (MBC) patients remains controversial.\nOBJECTIVE: The aim of our study was to evaluate the impact of LRT on OS in a large retrospective cohort of de novo MBC patients, with regard to immunohistochemical characteristics and pattern of metastatic dissemination.\nMETHODS: We conducted a multicentric retrospective study of patients diagnosed with de novo MBC selected from the French Epidemiological Strategy and Medical Economics MBC database (NCT03275311) between 2008 and 2014. Overall, 4276 women were included in the study. LRT comprised either radiotherapy, surgery, or both.\nRESULTS: LRT was used in 40% of patients. Compared with no LRT, patients who received LRT were younger (p\u2009<\u20090.0001) and were more likely to have only one metastatic site (p\u2009<\u20090.0001) or bone-only metastases (p\u2009<\u20090.0001). LRT was associated with a significantly better OS based on landmark multivariate analysis at 1-year (hazard ratio 0.65, 95% confidence interval 0.55-0.76, p\u2009<\u20090.001). Similar results were observed in all sensitivity analyses, including propensity score matching. In subgroup analysis, LRT was associated with better OS in patients with hormone receptor-positive/human epidermal growth factor receptor 2 (HER2)-negative (61.6 vs. 45.9\u00a0months, p\u2009<\u20090.001) and HER2-positive tumors (77.2 vs. 52.6\u00a0months, p\u2009=\u20090.008), but not in triple-negative tumors (19 vs. 18.6\u00a0months, p\u2009=\u20090.54), and was also associated with a reduction in the risk of death in visceral metastatic patients (p\u2009<\u20090.001).\nCONCLUSIONS: LRT was associated with a significantly better OS in de novo MBC patients, including patients with visceral involvement at diagnosis; however, LRT did not impact OS in triple-negative MBC.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1245/s10434-018-6831-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1105545", 
        "issn": [
          "1068-9265", 
          "1534-4681"
        ], 
        "name": "Annals of Surgical Oncology", 
        "type": "Periodical"
      }
    ], 
    "name": "Survival Impact of Locoregional Treatment of the Primary Tumor in De Novo Metastatic Breast Cancers in a Large Multicentric Cohort Study: A Propensity Score-Matched Analysis", 
    "pagination": "1-10", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "96f8bc0e2313c84b9d7d16937f496c6e35f0abd99105d8ece90564debcc0cdca"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30539492"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9420840"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1245/s10434-018-6831-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1110542256"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1245/s10434-018-6831-9", 
      "https://app.dimensions.ai/details/publication/pub.1110542256"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T08:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000309_0000000309/records_106277_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1245%2Fs10434-018-6831-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6831-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6831-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6831-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6831-9'


 

This table displays all metadata directly associated to this object as RDF triples.

401 TRIPLES      21 PREDICATES      62 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1245/s10434-018-6831-9 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N4523975c14994ed3a86603d788cf74da
4 schema:citation sg:pub.10.1007/s10549-008-0101-7
5 sg:pub.10.1007/s10549-011-1349-x
6 sg:pub.10.1007/s10549-011-1648-2
7 sg:pub.10.1007/s10549-016-4080-9
8 sg:pub.10.1007/s10585-015-9697-2
9 sg:pub.10.1007/s12032-012-0310-0
10 sg:pub.10.1038/bjc.2015.127
11 sg:pub.10.1038/nrclinonc.2014.96
12 sg:pub.10.1245/aso.2006.03.033
13 sg:pub.10.1245/s10434-007-9438-0
14 sg:pub.10.1245/s10434-007-9527-0
15 sg:pub.10.1245/s10434-008-0085-x
16 sg:pub.10.1245/s10434-013-2998-2
17 sg:pub.10.1245/s10434-018-6494-6
18 https://doi.org/10.1001/jamasurg.2015.4539
19 https://doi.org/10.1002/cncr.23870
20 https://doi.org/10.1002/cncr.24873
21 https://doi.org/10.1002/pds.3891
22 https://doi.org/10.1016/j.breast.2016.10.001
23 https://doi.org/10.1016/j.ejso.2009.03.012
24 https://doi.org/10.1016/j.ijrobp.2011.08.036
25 https://doi.org/10.1016/j.radonc.2010.02.028
26 https://doi.org/10.1016/s1470-2045(13)70130-x
27 https://doi.org/10.1016/s1470-2045(15)00135-7
28 https://doi.org/10.1056/nejmoa1607303
29 https://doi.org/10.1056/nejmoa1609709
30 https://doi.org/10.1067/msy.2002.127544
31 https://doi.org/10.1093/annonc/mdq220
32 https://doi.org/10.1097/sla.0000000000001302
33 https://doi.org/10.1097/sla.0b013e3181656d32
34 https://doi.org/10.1200/jco.2004.08.095
35 https://doi.org/10.1200/jco.2005.04.2226
36 https://doi.org/10.1200/jco.2008.19.5396
37 https://doi.org/10.18632/oncotarget.15856
38 https://doi.org/10.5858/arpa.2013-0953-sa
39 schema:datePublished 2019-02
40 schema:datePublishedReg 2019-02-01
41 schema:description INTRODUCTION: Improvement in overall survival (OS) by locoregional treatment (LRT) of the primary tumor in de novo metastatic breast cancer (MBC) patients remains controversial. OBJECTIVE: The aim of our study was to evaluate the impact of LRT on OS in a large retrospective cohort of de novo MBC patients, with regard to immunohistochemical characteristics and pattern of metastatic dissemination. METHODS: We conducted a multicentric retrospective study of patients diagnosed with de novo MBC selected from the French Epidemiological Strategy and Medical Economics MBC database (NCT03275311) between 2008 and 2014. Overall, 4276 women were included in the study. LRT comprised either radiotherapy, surgery, or both. RESULTS: LRT was used in 40% of patients. Compared with no LRT, patients who received LRT were younger (p < 0.0001) and were more likely to have only one metastatic site (p < 0.0001) or bone-only metastases (p < 0.0001). LRT was associated with a significantly better OS based on landmark multivariate analysis at 1-year (hazard ratio 0.65, 95% confidence interval 0.55-0.76, p < 0.001). Similar results were observed in all sensitivity analyses, including propensity score matching. In subgroup analysis, LRT was associated with better OS in patients with hormone receptor-positive/human epidermal growth factor receptor 2 (HER2)-negative (61.6 vs. 45.9 months, p < 0.001) and HER2-positive tumors (77.2 vs. 52.6 months, p = 0.008), but not in triple-negative tumors (19 vs. 18.6 months, p = 0.54), and was also associated with a reduction in the risk of death in visceral metastatic patients (p < 0.001). CONCLUSIONS: LRT was associated with a significantly better OS in de novo MBC patients, including patients with visceral involvement at diagnosis; however, LRT did not impact OS in triple-negative MBC.
42 schema:genre research_article
43 schema:inLanguage en
44 schema:isAccessibleForFree false
45 schema:isPartOf sg:journal.1105545
46 schema:name Survival Impact of Locoregional Treatment of the Primary Tumor in De Novo Metastatic Breast Cancers in a Large Multicentric Cohort Study: A Propensity Score-Matched Analysis
47 schema:pagination 1-10
48 schema:productId N04dff23a16b746919d5121dfc2295a15
49 N94770379d9b74d68b356e54f4f8ac06b
50 N94aa9bfe673844e28e6b09bfe8b6298f
51 Nd684a1b0b5ca48f1acdd1b9aec874c7b
52 Ndf0e8d287cb04580ab45b793663c3441
53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1110542256
54 https://doi.org/10.1245/s10434-018-6831-9
55 schema:sdDatePublished 2019-04-11T08:31
56 schema:sdLicense https://scigraph.springernature.com/explorer/license/
57 schema:sdPublisher Nb2db24c97ea9498bb5ec1f527e300702
58 schema:url https://link.springer.com/10.1245%2Fs10434-018-6831-9
59 sgo:license sg:explorer/license/
60 sgo:sdDataset articles
61 rdf:type schema:ScholarlyArticle
62 N028b94fb3d574ad7b1a030f5d08d338d schema:name Department of Medical Oncology, Claudius Regaud Institute, IUCT-Oncopole, Toulouse Cedex 09, France
63 rdf:type schema:Organization
64 N03256a6bf1044fadb5ccd2d425fcfefe rdf:first sg:person.01054656706.61
65 rdf:rest N2a93e53d9c1945019a77e0ccd5c062d4
66 N04dff23a16b746919d5121dfc2295a15 schema:name doi
67 schema:value 10.1245/s10434-018-6831-9
68 rdf:type schema:PropertyValue
69 N0d8099b4b069493192521902b0fb1072 schema:name Department of Medical Oncology, Jean Perrin Center, Clermont-Ferrand, France
70 rdf:type schema:Organization
71 N0e98ae9df3424c7684ed1215f2dd5626 rdf:first sg:person.0664373351.56
72 rdf:rest Na8de1a3d66f24a51971b4b894b7529a4
73 N189767af51814e5191e185ddb1b9c8aa schema:affiliation N3e8529780348448d8fbdaa6584cb77cc
74 schema:familyName Petit
75 schema:givenName Thierry
76 rdf:type schema:Person
77 N1da01f5b78044df0926c5930d04e2300 schema:name Department of Surgery, Henri Becquerel Center, Rouen, France
78 rdf:type schema:Organization
79 N1db6005c3d7c4cea8d899b8c6c471b2f rdf:first N53eaf82149454b2bac1d5de87d6a5bf0
80 rdf:rest N8c82d392cbac42b99a21714c316191ed
81 N251bd6007a434e36939e240c8804da70 schema:name Department of Surgery, Georges-François Leclerc Center, Dijon, France
82 rdf:type schema:Organization
83 N26d842e290064835879d7c329e507036 rdf:first sg:person.01036227135.61
84 rdf:rest Nfcd7337422b54e62a7aabef0f1e9ecdf
85 N27540e00781640589b18cf1f11106661 schema:name Department of Radiation Oncology, François Baclesse Center, Caen, France
86 rdf:type schema:Organization
87 N2a93e53d9c1945019a77e0ccd5c062d4 rdf:first sg:person.01200110513.56
88 rdf:rest Nd3a8c100a5d0498c8c9a5bcc2d9c8b9d
89 N31d479e0924b4f8d8611a401c79ec95e rdf:first sg:person.01141676130.49
90 rdf:rest Nba57afa530d142cea1af0cfe41471995
91 N3e8529780348448d8fbdaa6584cb77cc schema:name Department of Medical Oncology, Paul Strauss Center, Strasbourg, France
92 rdf:type schema:Organization
93 N42b4102d39e7441ca39f2be925ea47a4 schema:name Department of Medical Oncology, Antoine Lacassagne Cancer Center, Nice, France
94 rdf:type schema:Organization
95 N4523975c14994ed3a86603d788cf74da rdf:first sg:person.014377440763.42
96 rdf:rest Nbfdad8548c684963873ef0791db1d9f6
97 N53eaf82149454b2bac1d5de87d6a5bf0 schema:affiliation https://www.grid.ac/institutes/grid.418443.e
98 schema:familyName Gonçalves
99 schema:givenName Anthony
100 rdf:type schema:Person
101 N5f6a5636a0e747a49dcd08b2da51ec94 schema:name Department of Biostatistics, Claudius Regaud Institute, IUCT-Oncopole, Toulouse, France
102 rdf:type schema:Organization
103 N615c5685501f41d1bdda85c6241492c1 rdf:first sg:person.015334663367.95
104 rdf:rest N9666d0ba63ae438eb980439b7d140fb1
105 N6f59f0c936894af09d5d7b811b961e5e schema:name Department of Medical Oncology, Claudius Regaud Institute, IUCT-Oncopole, Toulouse Cedex 09, France
106 rdf:type schema:Organization
107 N7f7b74d8266a4c779799cb4db273fb8a rdf:first sg:person.0603415564.91
108 rdf:rest Nb761d1196e104fe8955da7e0809c69f7
109 N840f11be9aa5456a830cf26d384575c1 rdf:first sg:person.01007755571.44
110 rdf:rest Ne8f284623f30476babd85cab7dd0dfff
111 N88609f4ba0584e0ba6a563093193a4a4 rdf:first Nc8025ce0438a4867a1d8907ae17b3ee5
112 rdf:rest N96a104d801bb40e5906c8e51415b461d
113 N88c213c97d444041a243e6a32d1805df schema:name Department of Research and Development, R&D Unicancer, Paris, France
114 rdf:type schema:Organization
115 N8c82d392cbac42b99a21714c316191ed rdf:first Ndefbc249277f49d3acc91baa666ac97a
116 rdf:rest Nf9114ea51c174d879e3f9ee4d2a16571
117 N94770379d9b74d68b356e54f4f8ac06b schema:name readcube_id
118 schema:value 96f8bc0e2313c84b9d7d16937f496c6e35f0abd99105d8ece90564debcc0cdca
119 rdf:type schema:PropertyValue
120 N94aa9bfe673844e28e6b09bfe8b6298f schema:name pubmed_id
121 schema:value 30539492
122 rdf:type schema:PropertyValue
123 N95e921515edd459ebf966604ca39e946 schema:name Department of Biostatistics, Claudius Regaud Institute, IUCT-Oncopole, Toulouse, France
124 rdf:type schema:Organization
125 N9666d0ba63ae438eb980439b7d140fb1 rdf:first sg:person.01014626365.81
126 rdf:rest N31d479e0924b4f8d8611a401c79ec95e
127 N96a104d801bb40e5906c8e51415b461d rdf:first N9e528dc77fd54566b4c8f59b4a9dc76a
128 rdf:rest rdf:nil
129 N9e528dc77fd54566b4c8f59b4a9dc76a schema:affiliation N028b94fb3d574ad7b1a030f5d08d338d
130 schema:familyName Dalenc
131 schema:givenName Florence
132 rdf:type schema:Person
133 Na721be723ed740f7869525c3404b7234 schema:affiliation N1da01f5b78044df0926c5930d04e2300
134 schema:familyName Crouzet
135 schema:givenName Agathe
136 rdf:type schema:Person
137 Na89ca948cd1b403ca5ffc2b1f5979ed0 schema:affiliation Nf8ef00bfebd74a9fa0fd576116bc9674
138 schema:familyName Eymard
139 schema:givenName Jean-Christophe
140 rdf:type schema:Person
141 Na8de1a3d66f24a51971b4b894b7529a4 rdf:first sg:person.01243677536.09
142 rdf:rest N615c5685501f41d1bdda85c6241492c1
143 Nb2db24c97ea9498bb5ec1f527e300702 schema:name Springer Nature - SN SciGraph project
144 rdf:type schema:Organization
145 Nb761d1196e104fe8955da7e0809c69f7 rdf:first Na721be723ed740f7869525c3404b7234
146 rdf:rest N1db6005c3d7c4cea8d899b8c6c471b2f
147 Nba57afa530d142cea1af0cfe41471995 rdf:first Na89ca948cd1b403ca5ffc2b1f5979ed0
148 rdf:rest Nf65b23938bc54fb282cf13fc73e81ff7
149 Nbfdad8548c684963873ef0791db1d9f6 rdf:first sg:person.01310327270.45
150 rdf:rest N840f11be9aa5456a830cf26d384575c1
151 Nc8025ce0438a4867a1d8907ae17b3ee5 schema:affiliation N88c213c97d444041a243e6a32d1805df
152 schema:familyName Cailliot
153 schema:givenName Christian
154 rdf:type schema:Person
155 Nd3a8c100a5d0498c8c9a5bcc2d9c8b9d rdf:first sg:person.0621671544.20
156 rdf:rest N26d842e290064835879d7c329e507036
157 Nd4b84bcf85bc47b8874623cc2cde9642 rdf:first sg:person.07727141021.49
158 rdf:rest Neb12436269d449a6b195370de23efab1
159 Nd684a1b0b5ca48f1acdd1b9aec874c7b schema:name nlm_unique_id
160 schema:value 9420840
161 rdf:type schema:PropertyValue
162 Ndefbc249277f49d3acc91baa666ac97a schema:affiliation N251bd6007a434e36939e240c8804da70
163 schema:familyName Jankowski
164 schema:givenName Clémentine
165 rdf:type schema:Person
166 Ndf0e8d287cb04580ab45b793663c3441 schema:name dimensions_id
167 schema:value pub.1110542256
168 rdf:type schema:PropertyValue
169 Ne8f284623f30476babd85cab7dd0dfff rdf:first sg:person.0773526204.78
170 rdf:rest N03256a6bf1044fadb5ccd2d425fcfefe
171 Ne8fbce5b8240421fa10aff1746d8d954 schema:affiliation N95e921515edd459ebf966604ca39e946
172 schema:familyName Filleron
173 schema:givenName Thomas
174 rdf:type schema:Person
175 Neb12436269d449a6b195370de23efab1 rdf:first Ne8fbce5b8240421fa10aff1746d8d954
176 rdf:rest N88609f4ba0584e0ba6a563093193a4a4
177 Nf1b81d3a2c9d4a90bccc5678401ad5ed schema:name Department of Medical Oncology, Eugène Marquis Center, Rennes, France
178 rdf:type schema:Organization
179 Nf398b3acbcad42a4a5e9a37ae28561dd rdf:first N189767af51814e5191e185ddb1b9c8aa
180 rdf:rest Nd4b84bcf85bc47b8874623cc2cde9642
181 Nf65b23938bc54fb282cf13fc73e81ff7 rdf:first sg:person.0677500261.85
182 rdf:rest Nf398b3acbcad42a4a5e9a37ae28561dd
183 Nf8ef00bfebd74a9fa0fd576116bc9674 schema:name Department of Medical Oncology, Jean Godinot Institute, Reims, France
184 rdf:type schema:Organization
185 Nf9114ea51c174d879e3f9ee4d2a16571 rdf:first sg:person.01167112202.32
186 rdf:rest N0e98ae9df3424c7684ed1215f2dd5626
187 Nfcd7337422b54e62a7aabef0f1e9ecdf rdf:first sg:person.01210731760.28
188 rdf:rest N7f7b74d8266a4c779799cb4db273fb8a
189 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
190 schema:name Medical and Health Sciences
191 rdf:type schema:DefinedTerm
192 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
193 schema:name Clinical Sciences
194 rdf:type schema:DefinedTerm
195 sg:journal.1105545 schema:issn 1068-9265
196 1534-4681
197 schema:name Annals of Surgical Oncology
198 rdf:type schema:Periodical
199 sg:person.01007755571.44 schema:affiliation N5f6a5636a0e747a49dcd08b2da51ec94
200 schema:familyName Lusque
201 schema:givenName Amélie
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007755571.44
203 rdf:type schema:Person
204 sg:person.01014626365.81 schema:affiliation N42b4102d39e7441ca39f2be925ea47a4
205 schema:familyName Ferrero
206 schema:givenName Jean-Marc
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014626365.81
208 rdf:type schema:Person
209 sg:person.01036227135.61 schema:affiliation https://www.grid.ac/institutes/grid.452351.4
210 schema:familyName Pasquier
211 schema:givenName David
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036227135.61
213 rdf:type schema:Person
214 sg:person.01054656706.61 schema:affiliation N27540e00781640589b18cf1f11106661
215 schema:familyName Geffrelot
216 schema:givenName Julien
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054656706.61
218 rdf:type schema:Person
219 sg:person.01141676130.49 schema:affiliation https://www.grid.ac/institutes/grid.452436.2
220 schema:familyName Uwer
221 schema:givenName Lionel
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141676130.49
223 rdf:type schema:Person
224 sg:person.01167112202.32 schema:affiliation Nf1b81d3a2c9d4a90bccc5678401ad5ed
225 schema:familyName De La Motte Rouge
226 schema:givenName Thibault
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167112202.32
228 rdf:type schema:Person
229 sg:person.01200110513.56 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
230 schema:familyName Mazouni
231 schema:givenName Chafika
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01200110513.56
233 rdf:type schema:Person
234 sg:person.01210731760.28 schema:affiliation https://www.grid.ac/institutes/grid.476460.7
235 schema:familyName Madranges
236 schema:givenName Nicolas
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210731760.28
238 rdf:type schema:Person
239 sg:person.01243677536.09 schema:affiliation https://www.grid.ac/institutes/grid.418596.7
240 schema:familyName de La Lande
241 schema:givenName Brigitte
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243677536.09
243 rdf:type schema:Person
244 sg:person.01310327270.45 schema:affiliation https://www.grid.ac/institutes/grid.418596.7
245 schema:familyName Kirova
246 schema:givenName Youlia
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310327270.45
248 rdf:type schema:Person
249 sg:person.014377440763.42 schema:affiliation N6f59f0c936894af09d5d7b811b961e5e
250 schema:familyName Pons-Tostivint
251 schema:givenName Elvire
252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014377440763.42
253 rdf:type schema:Person
254 sg:person.015334663367.95 schema:affiliation https://www.grid.ac/institutes/grid.418596.7
255 schema:familyName Mouttet-Boizat
256 schema:givenName Delphine
257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015334663367.95
258 rdf:type schema:Person
259 sg:person.0603415564.91 schema:affiliation https://www.grid.ac/institutes/grid.418189.d
260 schema:familyName Firmin
261 schema:givenName Nelly
262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603415564.91
263 rdf:type schema:Person
264 sg:person.0621671544.20 schema:affiliation https://www.grid.ac/institutes/grid.452351.4
265 schema:familyName Mailliez
266 schema:givenName Audrey
267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621671544.20
268 rdf:type schema:Person
269 sg:person.0664373351.56 schema:affiliation https://www.grid.ac/institutes/grid.418596.7
270 schema:familyName Pouget
271 schema:givenName Nicolas
272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664373351.56
273 rdf:type schema:Person
274 sg:person.0677500261.85 schema:affiliation N0d8099b4b069493192521902b0fb1072
275 schema:familyName Mouret-Reynier
276 schema:givenName Marie-Ange
277 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677500261.85
278 rdf:type schema:Person
279 sg:person.07727141021.49 schema:affiliation https://www.grid.ac/institutes/grid.418596.7
280 schema:familyName Robain
281 schema:givenName Mathieu
282 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07727141021.49
283 rdf:type schema:Person
284 sg:person.0773526204.78 schema:affiliation https://www.grid.ac/institutes/grid.418191.4
285 schema:familyName Campone
286 schema:givenName Mario
287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773526204.78
288 rdf:type schema:Person
289 sg:pub.10.1007/s10549-008-0101-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034009384
290 https://doi.org/10.1007/s10549-008-0101-7
291 rdf:type schema:CreativeWork
292 sg:pub.10.1007/s10549-011-1349-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018282929
293 https://doi.org/10.1007/s10549-011-1349-x
294 rdf:type schema:CreativeWork
295 sg:pub.10.1007/s10549-011-1648-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035423148
296 https://doi.org/10.1007/s10549-011-1648-2
297 rdf:type schema:CreativeWork
298 sg:pub.10.1007/s10549-016-4080-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004362669
299 https://doi.org/10.1007/s10549-016-4080-9
300 rdf:type schema:CreativeWork
301 sg:pub.10.1007/s10585-015-9697-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016498846
302 https://doi.org/10.1007/s10585-015-9697-2
303 rdf:type schema:CreativeWork
304 sg:pub.10.1007/s12032-012-0310-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043686498
305 https://doi.org/10.1007/s12032-012-0310-0
306 rdf:type schema:CreativeWork
307 sg:pub.10.1038/bjc.2015.127 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050007381
308 https://doi.org/10.1038/bjc.2015.127
309 rdf:type schema:CreativeWork
310 sg:pub.10.1038/nrclinonc.2014.96 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045616176
311 https://doi.org/10.1038/nrclinonc.2014.96
312 rdf:type schema:CreativeWork
313 sg:pub.10.1245/aso.2006.03.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019710369
314 https://doi.org/10.1245/aso.2006.03.033
315 rdf:type schema:CreativeWork
316 sg:pub.10.1245/s10434-007-9438-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027122144
317 https://doi.org/10.1245/s10434-007-9438-0
318 rdf:type schema:CreativeWork
319 sg:pub.10.1245/s10434-007-9527-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049119926
320 https://doi.org/10.1245/s10434-007-9527-0
321 rdf:type schema:CreativeWork
322 sg:pub.10.1245/s10434-008-0085-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020882576
323 https://doi.org/10.1245/s10434-008-0085-x
324 rdf:type schema:CreativeWork
325 sg:pub.10.1245/s10434-013-2998-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024375344
326 https://doi.org/10.1245/s10434-013-2998-2
327 rdf:type schema:CreativeWork
328 sg:pub.10.1245/s10434-018-6494-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1104049156
329 https://doi.org/10.1245/s10434-018-6494-6
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1001/jamasurg.2015.4539 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000023771
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1002/cncr.23870 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009180128
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1002/cncr.24873 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033417427
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1002/pds.3891 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044027705
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1016/j.breast.2016.10.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046767167
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1016/j.ejso.2009.03.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027586430
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1016/j.ijrobp.2011.08.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017514898
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1016/j.radonc.2010.02.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036869166
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1016/s1470-2045(13)70130-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014610655
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1016/s1470-2045(15)00135-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015580522
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1056/nejmoa1607303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005496514
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1056/nejmoa1609709 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045557388
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1067/msy.2002.127544 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032157462
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1093/annonc/mdq220 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037043739
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1097/sla.0000000000001302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035190392
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1097/sla.0b013e3181656d32 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001216623
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1200/jco.2004.08.095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035477967
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1200/jco.2005.04.2226 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050599872
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1200/jco.2008.19.5396 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039439476
368 rdf:type schema:CreativeWork
369 https://doi.org/10.18632/oncotarget.15856 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084372974
370 rdf:type schema:CreativeWork
371 https://doi.org/10.5858/arpa.2013-0953-sa schema:sameAs https://app.dimensions.ai/details/publication/pub.1023063099
372 rdf:type schema:CreativeWork
373 https://www.grid.ac/institutes/grid.14925.3b schema:alternateName Institut Gustave Roussy
374 schema:name Department of Surgery, Gustave Roussy Institute, Villejuif, France
375 rdf:type schema:Organization
376 https://www.grid.ac/institutes/grid.418189.d schema:alternateName UniCancer Group
377 schema:name Department of Medical Oncology, Institut du Cancer de Montpellier, Montpellier, France
378 rdf:type schema:Organization
379 https://www.grid.ac/institutes/grid.418191.4 schema:alternateName Institut de Cancérologie de l'Ouest
380 schema:name Department of Medical Oncology, René Gauducheau Center, Institut de Cancérologie de l’Ouest (ICO), Saint-Herblain, France
381 rdf:type schema:Organization
382 https://www.grid.ac/institutes/grid.418443.e schema:alternateName Institute Paoli-Calmettes
383 schema:name Department of Medical Oncology, Paoli-Calmettes Institute, Marseille, France
384 rdf:type schema:Organization
385 https://www.grid.ac/institutes/grid.418596.7 schema:alternateName Institute Curie
386 schema:name Biostatistics Unit, Curie Institute, PSL Research University, Paris, France
387 Department of Radiation Oncology, Curie Institute, Paris, France
388 Department of Radiation Oncology, René Huguenin Centre, Curie Institute, Saint-Cloud, France
389 Department of Surgery, Curie Institute, Paris, France
390 Department of Surgery, René Huguenin Centre, Curie Institute, Saint-Cloud, France
391 rdf:type schema:Organization
392 https://www.grid.ac/institutes/grid.452351.4 schema:alternateName Centre Oscar Lambret
393 schema:name Department of Medical Oncology, Oscar Lambret Center, Lille, France
394 Department of Radiation Oncology, Oscar Lambret Center, Lille, France
395 rdf:type schema:Organization
396 https://www.grid.ac/institutes/grid.452436.2 schema:alternateName Institut de Cancérologie de Lorraine
397 schema:name Department of Medical Oncology, Institut de Cancérologie de Lorraine, Vandoeuvre-lès-Nancy, France
398 rdf:type schema:Organization
399 https://www.grid.ac/institutes/grid.476460.7 schema:alternateName Institut Bergonié
400 schema:name Department of Medical Oncology, Bergonié Institute, Bordeaux, France
401 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...