The Impact of Education and Prescribing Guidelines on Opioid Prescribing for Breast and Melanoma Procedures View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-01

AUTHORS

Jay S. Lee, Ryan A. Howard, Michael P. Klueh, Michael J. Englesbe, Jennifer F. Waljee, Chad M. Brummett, Michael S. Sabel, Lesly A. Dossett

ABSTRACT

BACKGROUND: Excessive opioid prescribing is common in surgical oncology, with 72% of prescribed opioids going unused after curative-intent surgery. In this study, we sought to reduce opioid prescribing after breast and melanoma procedures by designing and implementing an intervention focused on education and prescribing guidelines, and then evaluating the impact of this intervention. METHODS: In this single-institution study, we designed and implemented an intervention targeting key factors identified in qualitative interviews. This included mandatory education for prescribers, evidence-based prescribing guidelines, and standardized patient instructions. After the intervention, interrupted time-series analysis was used to compare the mean quantity of opioid prescribed before and after the intervention (July 2016-September 2017). We also evaluated the frequency of opioid prescription refills. RESULTS: During the study, 847 patients underwent breast or melanoma procedures and received an opioid prescription. For mastectomy or wide local excision for melanoma, the mean quantity of opioid prescribed immediately decreased by 37% after the intervention (p = 0.03), equivalent to 13 tablets of oxycodone 5 mg. For lumpectomy or breast biopsy, the mean quantity of opioid prescribed decreased by 42%, or 12 tablets of oxycodone 5 mg (p = 0.07). Furthermore, opioid prescription refills did not significantly change for mastectomy/wide local excision (13% vs. 14%, p = 0.8), or lumpectomy/breast biopsy (4% vs. 5%, p = 0.7). CONCLUSION: Education and prescribing guidelines reduced opioid prescribing for breast and melanoma procedures without increasing the need for refills. This suggests further reductions in opioid prescribing may be possible, and provides rationale for implementing similar interventions for other procedures and practice settings. More... »

PAGES

1-8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1245/s10434-018-6772-3

DOI

http://dx.doi.org/10.1245/s10434-018-6772-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107121538

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30238243


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Michigan\u2013Ann Arbor", 
          "id": "https://www.grid.ac/institutes/grid.214458.e", 
          "name": [
            "Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA", 
            "Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Jay S.", 
        "id": "sg:person.01115102543.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115102543.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Michigan Medicine", 
          "id": "https://www.grid.ac/institutes/grid.412590.b", 
          "name": [
            "Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Howard", 
        "givenName": "Ryan A.", 
        "id": "sg:person.010107525716.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010107525716.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Michigan Medicine", 
          "id": "https://www.grid.ac/institutes/grid.412590.b", 
          "name": [
            "Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Klueh", 
        "givenName": "Michael P.", 
        "id": "sg:person.011274077324.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011274077324.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Michigan\u2013Ann Arbor", 
          "id": "https://www.grid.ac/institutes/grid.214458.e", 
          "name": [
            "Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA", 
            "Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Englesbe", 
        "givenName": "Michael J.", 
        "id": "sg:person.01116272233.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116272233.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Michigan\u2013Ann Arbor", 
          "id": "https://www.grid.ac/institutes/grid.214458.e", 
          "name": [
            "Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA", 
            "Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Waljee", 
        "givenName": "Jennifer F.", 
        "id": "sg:person.0724512470.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724512470.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Michigan\u2013Ann Arbor", 
          "id": "https://www.grid.ac/institutes/grid.214458.e", 
          "name": [
            "Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Brummett", 
        "givenName": "Chad M.", 
        "id": "sg:person.01355457075.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01355457075.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Michigan Medicine", 
          "id": "https://www.grid.ac/institutes/grid.412590.b", 
          "name": [
            "Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sabel", 
        "givenName": "Michael S.", 
        "id": "sg:person.0757207556.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757207556.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Michigan Medicine", 
          "id": "https://www.grid.ac/institutes/grid.412590.b", 
          "name": [
            "Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA", 
            "Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA", 
            "Division of Surgical Oncology, Michigan Medicine, Ann Arbor, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dossett", 
        "givenName": "Lesly A.", 
        "id": "sg:person.01070566471.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070566471.63"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1001/jama.2009.1568", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000666933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/aln.0b013e3182a8eb1f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001157466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/aln.0b013e3182a8eb1f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001157466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2013.49.1514", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001324596"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2011.39.7398", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007245163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/j.pain.0000000000000516", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008275735"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/j.pain.0000000000000516", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008275735"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2006.08.6652", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013417873"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(11)70002-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015604527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1099-1611(200101/02)10:1<19::aid-pon501>3.0.co;2-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018305551"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ije/dyw098", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025536159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.drugalcdep.2016.08.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030542514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.drugalcdep.2016.08.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030542514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002508-200309000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032387878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002508-200309000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032387878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pain.2005.09.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032959899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pain.2005.09.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032959899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0147972", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034035843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001993", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034431632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001993", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034431632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jhsa.2012.01.035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039369049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamadermatol.2013.1871", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044047180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.juro.2010.09.088", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047731947"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/aln.0000000000000637", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060337634"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/aln.0000000000000637", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060337634"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/aln.0000000000000637", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060337634"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/spv.0000000000000299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060344812"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/spv.0000000000000299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060344812"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/spv.0000000000000299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060344812"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.15.00614", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068898160"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.15.00614", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068898160"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.15.00614", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068898160"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000002198", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084196697"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000002198", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084196697"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamasurg.2017.0504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084813244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.2017.2827", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085415875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000002308", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085918173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000002308", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085918173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000002308", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085918173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000002308", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085918173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamasurg.2017.0831", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090951453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2017.74.1363", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092304141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000002591", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099609114"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000002591", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099609114"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000002591", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099609114"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamasurg.2017.4436", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099609754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamasurg.2017.4436", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099609754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamasurg.2017.4436", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099609754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-018-6466-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103210342", 
          "https://doi.org/10.1245/s10434-018-6466-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-018-6466-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103210342", 
          "https://doi.org/10.1245/s10434-018-6466-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11606-018-4463-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104525504", 
          "https://doi.org/10.1007/s11606-018-4463-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11606-018-4463-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104525504", 
          "https://doi.org/10.1007/s11606-018-4463-1"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-01", 
    "datePublishedReg": "2019-01-01", 
    "description": "BACKGROUND: Excessive opioid prescribing is common in surgical oncology, with 72% of prescribed opioids going unused after curative-intent surgery. In this study, we sought to reduce opioid prescribing after breast and melanoma procedures by designing and implementing an intervention focused on education and prescribing guidelines, and then evaluating the impact of this intervention.\nMETHODS: In this single-institution study, we designed and implemented an intervention targeting key factors identified in qualitative interviews. This included mandatory education for prescribers, evidence-based prescribing guidelines, and standardized patient instructions. After the intervention, interrupted time-series analysis was used to compare the mean quantity of opioid prescribed before and after the intervention (July 2016-September 2017). We also evaluated the frequency of opioid prescription refills.\nRESULTS: During the study, 847 patients underwent breast or melanoma procedures and received an opioid prescription. For mastectomy or wide local excision for melanoma, the mean quantity of opioid prescribed immediately decreased by 37% after the intervention (p\u2009=\u20090.03), equivalent to 13 tablets of oxycodone 5\u00a0mg. For lumpectomy or breast biopsy, the mean quantity of opioid prescribed decreased by 42%, or 12 tablets of oxycodone 5\u00a0mg (p\u2009=\u20090.07). Furthermore, opioid prescription refills did not significantly change for mastectomy/wide local excision (13% vs. 14%, p\u2009=\u20090.8), or lumpectomy/breast biopsy (4% vs. 5%, p\u2009=\u20090.7).\nCONCLUSION: Education and prescribing guidelines reduced opioid prescribing for breast and melanoma procedures without increasing the need for refills. This suggests further reductions in opioid prescribing may be possible, and provides rationale for implementing similar interventions for other procedures and practice settings.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1245/s10434-018-6772-3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.6953241", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2682666", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1105545", 
        "issn": [
          "1068-9265", 
          "1534-4681"
        ], 
        "name": "Annals of Surgical Oncology", 
        "type": "Periodical"
      }
    ], 
    "name": "The Impact of Education and Prescribing Guidelines on Opioid Prescribing for Breast and Melanoma Procedures", 
    "pagination": "1-8", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "c0f708f412ca65ece93bcb382f36fcada8259de6026e4f932f627773fc49f311"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30238243"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9420840"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1245/s10434-018-6772-3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1107121538"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1245/s10434-018-6772-3", 
      "https://app.dimensions.ai/details/publication/pub.1107121538"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T22:40", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8690_00000560.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1245%2Fs10434-018-6772-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6772-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6772-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6772-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6772-3'


 

This table displays all metadata directly associated to this object as RDF triples.

215 TRIPLES      21 PREDICATES      57 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1245/s10434-018-6772-3 schema:about anzsrc-for:11
2 anzsrc-for:1117
3 schema:author N6cf691b1db3147619ed88e00b257afe6
4 schema:citation sg:pub.10.1007/s11606-018-4463-1
5 sg:pub.10.1245/s10434-018-6466-x
6 https://doi.org/10.1001/jama.2009.1568
7 https://doi.org/10.1001/jama.2017.2827
8 https://doi.org/10.1001/jamadermatol.2013.1871
9 https://doi.org/10.1001/jamasurg.2017.0504
10 https://doi.org/10.1001/jamasurg.2017.0831
11 https://doi.org/10.1001/jamasurg.2017.4436
12 https://doi.org/10.1002/1099-1611(200101/02)10:1<19::aid-pon501>3.0.co;2-6
13 https://doi.org/10.1016/j.drugalcdep.2016.08.016
14 https://doi.org/10.1016/j.jhsa.2012.01.035
15 https://doi.org/10.1016/j.juro.2010.09.088
16 https://doi.org/10.1016/j.pain.2005.09.014
17 https://doi.org/10.1016/s1470-2045(11)70002-x
18 https://doi.org/10.1093/ije/dyw098
19 https://doi.org/10.1097/00002508-200309000-00002
20 https://doi.org/10.1097/aln.0000000000000637
21 https://doi.org/10.1097/aln.0b013e3182a8eb1f
22 https://doi.org/10.1097/j.pain.0000000000000516
23 https://doi.org/10.1097/sla.0000000000001993
24 https://doi.org/10.1097/sla.0000000000002198
25 https://doi.org/10.1097/sla.0000000000002308
26 https://doi.org/10.1097/sla.0000000000002591
27 https://doi.org/10.1097/spv.0000000000000299
28 https://doi.org/10.1200/jco.2006.08.6652
29 https://doi.org/10.1200/jco.2011.39.7398
30 https://doi.org/10.1200/jco.2013.49.1514
31 https://doi.org/10.1200/jco.2017.74.1363
32 https://doi.org/10.1371/journal.pone.0147972
33 https://doi.org/10.2106/jbjs.15.00614
34 schema:datePublished 2019-01
35 schema:datePublishedReg 2019-01-01
36 schema:description BACKGROUND: Excessive opioid prescribing is common in surgical oncology, with 72% of prescribed opioids going unused after curative-intent surgery. In this study, we sought to reduce opioid prescribing after breast and melanoma procedures by designing and implementing an intervention focused on education and prescribing guidelines, and then evaluating the impact of this intervention. METHODS: In this single-institution study, we designed and implemented an intervention targeting key factors identified in qualitative interviews. This included mandatory education for prescribers, evidence-based prescribing guidelines, and standardized patient instructions. After the intervention, interrupted time-series analysis was used to compare the mean quantity of opioid prescribed before and after the intervention (July 2016-September 2017). We also evaluated the frequency of opioid prescription refills. RESULTS: During the study, 847 patients underwent breast or melanoma procedures and received an opioid prescription. For mastectomy or wide local excision for melanoma, the mean quantity of opioid prescribed immediately decreased by 37% after the intervention (p = 0.03), equivalent to 13 tablets of oxycodone 5 mg. For lumpectomy or breast biopsy, the mean quantity of opioid prescribed decreased by 42%, or 12 tablets of oxycodone 5 mg (p = 0.07). Furthermore, opioid prescription refills did not significantly change for mastectomy/wide local excision (13% vs. 14%, p = 0.8), or lumpectomy/breast biopsy (4% vs. 5%, p = 0.7). CONCLUSION: Education and prescribing guidelines reduced opioid prescribing for breast and melanoma procedures without increasing the need for refills. This suggests further reductions in opioid prescribing may be possible, and provides rationale for implementing similar interventions for other procedures and practice settings.
37 schema:genre research_article
38 schema:inLanguage en
39 schema:isAccessibleForFree false
40 schema:isPartOf sg:journal.1105545
41 schema:name The Impact of Education and Prescribing Guidelines on Opioid Prescribing for Breast and Melanoma Procedures
42 schema:pagination 1-8
43 schema:productId N78aa1b85f44043ffb5ab4b3d356077f1
44 Nab823515e75e41d9b16695c567080b5d
45 Ne026caed659a40e9b2130403b5b111aa
46 Ne5d5d45aeb38449e939de8aa30d795bc
47 Ne8b33d00fb9a492893e95044fa23fe75
48 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107121538
49 https://doi.org/10.1245/s10434-018-6772-3
50 schema:sdDatePublished 2019-04-10T22:40
51 schema:sdLicense https://scigraph.springernature.com/explorer/license/
52 schema:sdPublisher N6aefab7eb94b4ce289e183dc0f1d3f9b
53 schema:url http://link.springer.com/10.1245%2Fs10434-018-6772-3
54 sgo:license sg:explorer/license/
55 sgo:sdDataset articles
56 rdf:type schema:ScholarlyArticle
57 N487218317ff64b05b6c8d35c7096dc25 rdf:first sg:person.01070566471.63
58 rdf:rest rdf:nil
59 N639083bdd01f4a54b16df504652d5ef2 rdf:first sg:person.0724512470.50
60 rdf:rest N7fe9a78a4b9643f59a2b6f6e940d557a
61 N6aefab7eb94b4ce289e183dc0f1d3f9b schema:name Springer Nature - SN SciGraph project
62 rdf:type schema:Organization
63 N6c1884f4e1be4321b4777c78055dd61e rdf:first sg:person.01116272233.54
64 rdf:rest N639083bdd01f4a54b16df504652d5ef2
65 N6cf691b1db3147619ed88e00b257afe6 rdf:first sg:person.01115102543.84
66 rdf:rest Nc2669ce52e6a471c829e49e3c82ac4f6
67 N78aa1b85f44043ffb5ab4b3d356077f1 schema:name readcube_id
68 schema:value c0f708f412ca65ece93bcb382f36fcada8259de6026e4f932f627773fc49f311
69 rdf:type schema:PropertyValue
70 N7fe9a78a4b9643f59a2b6f6e940d557a rdf:first sg:person.01355457075.71
71 rdf:rest Nfa3da08a79fe4621938797a7e29002eb
72 Nab823515e75e41d9b16695c567080b5d schema:name nlm_unique_id
73 schema:value 9420840
74 rdf:type schema:PropertyValue
75 Nb16b1d73c3594bdda673f1ae24754b19 rdf:first sg:person.011274077324.10
76 rdf:rest N6c1884f4e1be4321b4777c78055dd61e
77 Nc2669ce52e6a471c829e49e3c82ac4f6 rdf:first sg:person.010107525716.67
78 rdf:rest Nb16b1d73c3594bdda673f1ae24754b19
79 Ne026caed659a40e9b2130403b5b111aa schema:name doi
80 schema:value 10.1245/s10434-018-6772-3
81 rdf:type schema:PropertyValue
82 Ne5d5d45aeb38449e939de8aa30d795bc schema:name pubmed_id
83 schema:value 30238243
84 rdf:type schema:PropertyValue
85 Ne8b33d00fb9a492893e95044fa23fe75 schema:name dimensions_id
86 schema:value pub.1107121538
87 rdf:type schema:PropertyValue
88 Nfa3da08a79fe4621938797a7e29002eb rdf:first sg:person.0757207556.48
89 rdf:rest N487218317ff64b05b6c8d35c7096dc25
90 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
91 schema:name Medical and Health Sciences
92 rdf:type schema:DefinedTerm
93 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
94 schema:name Public Health and Health Services
95 rdf:type schema:DefinedTerm
96 sg:grant.2682666 http://pending.schema.org/fundedItem sg:pub.10.1245/s10434-018-6772-3
97 rdf:type schema:MonetaryGrant
98 sg:grant.6953241 http://pending.schema.org/fundedItem sg:pub.10.1245/s10434-018-6772-3
99 rdf:type schema:MonetaryGrant
100 sg:journal.1105545 schema:issn 1068-9265
101 1534-4681
102 schema:name Annals of Surgical Oncology
103 rdf:type schema:Periodical
104 sg:person.010107525716.67 schema:affiliation https://www.grid.ac/institutes/grid.412590.b
105 schema:familyName Howard
106 schema:givenName Ryan A.
107 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010107525716.67
108 rdf:type schema:Person
109 sg:person.01070566471.63 schema:affiliation https://www.grid.ac/institutes/grid.412590.b
110 schema:familyName Dossett
111 schema:givenName Lesly A.
112 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070566471.63
113 rdf:type schema:Person
114 sg:person.01115102543.84 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
115 schema:familyName Lee
116 schema:givenName Jay S.
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115102543.84
118 rdf:type schema:Person
119 sg:person.01116272233.54 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
120 schema:familyName Englesbe
121 schema:givenName Michael J.
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116272233.54
123 rdf:type schema:Person
124 sg:person.011274077324.10 schema:affiliation https://www.grid.ac/institutes/grid.412590.b
125 schema:familyName Klueh
126 schema:givenName Michael P.
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011274077324.10
128 rdf:type schema:Person
129 sg:person.01355457075.71 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
130 schema:familyName Brummett
131 schema:givenName Chad M.
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01355457075.71
133 rdf:type schema:Person
134 sg:person.0724512470.50 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
135 schema:familyName Waljee
136 schema:givenName Jennifer F.
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724512470.50
138 rdf:type schema:Person
139 sg:person.0757207556.48 schema:affiliation https://www.grid.ac/institutes/grid.412590.b
140 schema:familyName Sabel
141 schema:givenName Michael S.
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757207556.48
143 rdf:type schema:Person
144 sg:pub.10.1007/s11606-018-4463-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1104525504
145 https://doi.org/10.1007/s11606-018-4463-1
146 rdf:type schema:CreativeWork
147 sg:pub.10.1245/s10434-018-6466-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1103210342
148 https://doi.org/10.1245/s10434-018-6466-x
149 rdf:type schema:CreativeWork
150 https://doi.org/10.1001/jama.2009.1568 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000666933
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1001/jama.2017.2827 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085415875
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1001/jamadermatol.2013.1871 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044047180
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1001/jamasurg.2017.0504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084813244
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1001/jamasurg.2017.0831 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090951453
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1001/jamasurg.2017.4436 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099609754
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1002/1099-1611(200101/02)10:1<19::aid-pon501>3.0.co;2-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018305551
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1016/j.drugalcdep.2016.08.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030542514
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1016/j.jhsa.2012.01.035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039369049
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1016/j.juro.2010.09.088 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047731947
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1016/j.pain.2005.09.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032959899
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1016/s1470-2045(11)70002-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015604527
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1093/ije/dyw098 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025536159
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1097/00002508-200309000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032387878
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1097/aln.0000000000000637 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060337634
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1097/aln.0b013e3182a8eb1f schema:sameAs https://app.dimensions.ai/details/publication/pub.1001157466
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1097/j.pain.0000000000000516 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008275735
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1097/sla.0000000000001993 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034431632
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1097/sla.0000000000002198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084196697
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1097/sla.0000000000002308 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085918173
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1097/sla.0000000000002591 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099609114
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1097/spv.0000000000000299 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060344812
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1200/jco.2006.08.6652 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013417873
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1200/jco.2011.39.7398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007245163
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1200/jco.2013.49.1514 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001324596
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1200/jco.2017.74.1363 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092304141
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1371/journal.pone.0147972 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034035843
203 rdf:type schema:CreativeWork
204 https://doi.org/10.2106/jbjs.15.00614 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068898160
205 rdf:type schema:CreativeWork
206 https://www.grid.ac/institutes/grid.214458.e schema:alternateName University of Michigan–Ann Arbor
207 schema:name Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA
208 Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA
209 Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA
210 rdf:type schema:Organization
211 https://www.grid.ac/institutes/grid.412590.b schema:alternateName Michigan Medicine
212 schema:name Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA
213 Department of Surgery, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA
214 Division of Surgical Oncology, Michigan Medicine, Ann Arbor, MI, USA
215 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...