Salvage Surgery for Recurrent Retroperitoneal Well-Differentiated Liposarcoma: Early Reoperation may not Provide Benefit View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-08

AUTHORS

Naruhiko Ikoma, Christina L. Roland, Keila E. Torres, Yi-Ju Chiang, Wei-Lien Wang, Neeta Somaiah, Gary N. Mann, Kelly K. Hunt, Janice N. Cormier, Barry W. Feig

ABSTRACT

PURPOSE: Current evidence regarding salvage resection for recurrent retroperitoneal (RP) sarcomas generally lacks detailed histology-specific analyses, but the aggressiveness of these tumors varies widely by histology. We investigated associations between timing and extent of salvage surgery and survival outcomes in patients with recurrent RP well-differentiated liposarcoma (WDLPS). METHODS: The University of Texas MD Anderson Cancer Center Surgical Oncology sarcoma database was reviewed to identify patients with RP WDLPS who underwent surgical resection for first recurrent disease (salvage surgery) in 1995-2015. Medical records were retrospectively reviewed to identify factors associated with overall survival and disease-free survival. RESULTS: We identified 52 patients who underwent salvage surgery for RP WDLPS for first local recurrence; 28 (54%) underwent salvage surgery within 6 months after recurrence. Concomitant organ resections were performed in 32 (62%) patients, 4 (13%) of whom had pathologic invasion of resected organs. After R0/R1 resections (n = 45), 38 (84%) experienced a second local recurrence. Multivariable analyses revealed that organ invasion at the primary surgery [hazard ratio (HR) 13.08; p = 0.005] and disease-free interval < 1 year (HR 3.64; p = 0.044) were associated with shorter overall survival. Recurrence-to-salvage interval < 6 months was associated with shorter disease-free survival (HR 2.18; p = 0.025). Concomitant organ resection was associated with a longer hospital stay: ≥ 14 days (odds ratio 21.58; p = 0.007). CONCLUSIONS: Early salvage surgery may not always be the best approach for recurrent RP WDLPS patients. Because organ invasion is rare among recurrent RP WDLPS patients and concomitant organ resection is associated with a longer hospital stay, preservation of uninvolved organs should be considered. More... »

PAGES

2193-2200

Identifiers

URI

http://scigraph.springernature.com/pub.10.1245/s10434-018-6417-6

DOI

http://dx.doi.org/10.1245/s10434-018-6417-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1101382185

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29520652


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Length of Stay", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liposarcoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Invasiveness", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Recurrence, Local", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Patient Selection", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Postoperative Complications", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reoperation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retroperitoneal Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Salvage Therapy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Second-Look Surgery", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ikoma", 
        "givenName": "Naruhiko", 
        "id": "sg:person.010673117665.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010673117665.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roland", 
        "givenName": "Christina L.", 
        "id": "sg:person.01006236215.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006236215.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Torres", 
        "givenName": "Keila E.", 
        "id": "sg:person.01017635105.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017635105.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chiang", 
        "givenName": "Yi-Ju", 
        "id": "sg:person.01166770424.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01166770424.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wang", 
        "givenName": "Wei-Lien", 
        "id": "sg:person.010331373604.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010331373604.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Somaiah", 
        "givenName": "Neeta", 
        "id": "sg:person.01352620562.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01352620562.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mann", 
        "givenName": "Gary N.", 
        "id": "sg:person.07763437315.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07763437315.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hunt", 
        "givenName": "Kelly K.", 
        "id": "sg:person.01340214713.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340214713.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cormier", 
        "givenName": "Janice N.", 
        "id": "sg:person.0730564335.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730564335.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Feig", 
        "givenName": "Barry W.", 
        "id": "sg:person.0634233332.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634233332.35"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181928f2f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002112623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181928f2f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002112623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000108670.31446.54", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008133880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000108670.31446.54", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008133880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-008-0250-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008547685", 
          "https://doi.org/10.1245/s10434-008-0250-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.yasu.2015.04.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009194775"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jss.2010.07.056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011782026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-016-5523-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013821787", 
          "https://doi.org/10.1245/s10434-016-5523-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-016-5523-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013821787", 
          "https://doi.org/10.1245/s10434-016-5523-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001447", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014206895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001447", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014206895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001447", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014206895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.18.0802", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017397932"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-016-5344-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021317320", 
          "https://doi.org/10.1245/s10434-016-5344-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-016-5344-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021317320", 
          "https://doi.org/10.1245/s10434-016-5344-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-016-5344-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021317320", 
          "https://doi.org/10.1245/s10434-016-5344-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-016-5344-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021317320", 
          "https://doi.org/10.1245/s10434-016-5344-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022350348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0000000000001149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022350348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.18.7138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022382005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181b2468b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023369756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181b2468b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023369756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181b2468b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023369756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jamcollsurg.2009.12.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023610388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000133083.54934.ae", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024049438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000133083.54934.ae", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024049438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000133083.54934.ae", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024049438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/ejso.2001.1166", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025165333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1308/003588410x12771863936729", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029287410"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.17.8871", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040189711"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-014-4130-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040236094", 
          "https://doi.org/10.1245/s10434-014-4130-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3322/canjclin.56.5.282", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049471116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199809000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060134859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199809000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060134859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199809000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060134859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199809000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060134859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.30572", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083523188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.16345", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091756616"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-08", 
    "datePublishedReg": "2018-08-01", 
    "description": "PURPOSE: Current evidence regarding salvage resection for recurrent retroperitoneal (RP) sarcomas generally lacks detailed histology-specific analyses, but the aggressiveness of these tumors varies widely by histology. We investigated associations between timing and extent of salvage surgery and survival outcomes in patients with recurrent RP well-differentiated liposarcoma (WDLPS).\nMETHODS: The University of Texas MD Anderson Cancer Center Surgical Oncology sarcoma database was reviewed to identify patients with RP WDLPS who underwent surgical resection for first recurrent disease (salvage surgery) in 1995-2015. Medical records were retrospectively reviewed to identify factors associated with overall survival and disease-free survival.\nRESULTS: We identified 52 patients who underwent salvage surgery for RP WDLPS for first local recurrence; 28 (54%) underwent salvage surgery within 6\u00a0months after recurrence. Concomitant organ resections were performed in 32 (62%) patients, 4 (13%) of whom had pathologic invasion of resected organs. After R0/R1 resections (n\u2009=\u200945), 38 (84%) experienced a second local recurrence. Multivariable analyses revealed that organ invasion at the primary surgery [hazard ratio (HR) 13.08; p\u2009=\u20090.005] and disease-free interval\u2009<\u20091\u00a0year (HR 3.64; p\u2009=\u20090.044) were associated with shorter overall survival. Recurrence-to-salvage interval\u2009<\u20096\u00a0months was associated with shorter disease-free survival (HR 2.18; p\u2009=\u20090.025). Concomitant organ resection was associated with a longer hospital stay:\u2009\u2265\u200914\u00a0days (odds ratio 21.58; p\u2009=\u20090.007).\nCONCLUSIONS: Early salvage surgery may not always be the best approach for recurrent RP WDLPS patients. Because organ invasion is rare among recurrent RP WDLPS patients and concomitant organ resection is associated with a longer hospital stay, preservation of uninvolved organs should be considered.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1245/s10434-018-6417-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2438826", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1105545", 
        "issn": [
          "1068-9265", 
          "1534-4681"
        ], 
        "name": "Annals of Surgical Oncology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "8", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "25"
      }
    ], 
    "name": "Salvage Surgery for Recurrent Retroperitoneal Well-Differentiated Liposarcoma: Early Reoperation may not Provide Benefit", 
    "pagination": "2193-2200", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "236005223d383a1f62d85d7be7f5f4edcf790e54fdc70f54b81f199c563387dc"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29520652"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9420840"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1245/s10434-018-6417-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1101382185"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1245/s10434-018-6417-6", 
      "https://app.dimensions.ai/details/publication/pub.1101382185"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T11:51", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000359_0000000359/records_29183_00000003.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1245%2Fs10434-018-6417-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6417-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6417-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6417-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1245/s10434-018-6417-6'


 

This table displays all metadata directly associated to this object as RDF triples.

278 TRIPLES      21 PREDICATES      69 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1245/s10434-018-6417-6 schema:about N344286d537e74288842294d6dc7f767a
2 N3aed00045277437781c9ee76ee30c510
3 N463f421e43e743699c8747c70e387375
4 N4b1ed7c838164fe08fab52028ba518b9
5 N55be8f68af674fd0a95f956971e8c794
6 N8142a7bb19e34609bf2151beae7a8809
7 N873197a732e144f3bac1299a4f7f333b
8 N900926df4a0a4f9886c089e0c575f8df
9 N96a46cedca38421e8986d2117891e5b9
10 Nb6a77032a3c341928aa56ed1a297d4a1
11 Nb9bac550ed094a4b8817161066254388
12 Nbb4a8e532ff34438ac65ca07f0c193ed
13 Nbd0bea23006c4219ab4c676d87d574b4
14 Nd73964df060249e3b136d2cc20f37ba9
15 Nda1db6ecf40f45dd877463dd60c034fa
16 Nef56417253d1403fb0d3607a24495f57
17 Nfc5a716b605f42db949ca61429667761
18 Nfd66bc56a0024faa9a25656b9d207778
19 anzsrc-for:11
20 anzsrc-for:1112
21 schema:author N95e22d96326542e1a7bdefd003fe0431
22 schema:citation sg:pub.10.1245/s10434-008-0250-2
23 sg:pub.10.1245/s10434-014-4130-7
24 sg:pub.10.1245/s10434-016-5344-7
25 sg:pub.10.1245/s10434-016-5523-6
26 https://doi.org/10.1002/cncr.30572
27 https://doi.org/10.1016/j.jamcollsurg.2009.12.024
28 https://doi.org/10.1016/j.jss.2010.07.056
29 https://doi.org/10.1016/j.yasu.2015.04.002
30 https://doi.org/10.1053/ejso.2001.1166
31 https://doi.org/10.1097/00000658-199809000-00008
32 https://doi.org/10.1097/01.sla.0000108670.31446.54
33 https://doi.org/10.1097/01.sla.0000133083.54934.ae
34 https://doi.org/10.1097/sla.0000000000001149
35 https://doi.org/10.1097/sla.0000000000001447
36 https://doi.org/10.1097/sla.0b013e3181928f2f
37 https://doi.org/10.1097/sla.0b013e3181b2468b
38 https://doi.org/10.1200/jco.2008.17.8871
39 https://doi.org/10.1200/jco.2008.18.0802
40 https://doi.org/10.1200/jco.2008.18.7138
41 https://doi.org/10.1308/003588410x12771863936729
42 https://doi.org/10.18632/oncotarget.16345
43 https://doi.org/10.3322/canjclin.56.5.282
44 schema:datePublished 2018-08
45 schema:datePublishedReg 2018-08-01
46 schema:description PURPOSE: Current evidence regarding salvage resection for recurrent retroperitoneal (RP) sarcomas generally lacks detailed histology-specific analyses, but the aggressiveness of these tumors varies widely by histology. We investigated associations between timing and extent of salvage surgery and survival outcomes in patients with recurrent RP well-differentiated liposarcoma (WDLPS). METHODS: The University of Texas MD Anderson Cancer Center Surgical Oncology sarcoma database was reviewed to identify patients with RP WDLPS who underwent surgical resection for first recurrent disease (salvage surgery) in 1995-2015. Medical records were retrospectively reviewed to identify factors associated with overall survival and disease-free survival. RESULTS: We identified 52 patients who underwent salvage surgery for RP WDLPS for first local recurrence; 28 (54%) underwent salvage surgery within 6 months after recurrence. Concomitant organ resections were performed in 32 (62%) patients, 4 (13%) of whom had pathologic invasion of resected organs. After R0/R1 resections (n = 45), 38 (84%) experienced a second local recurrence. Multivariable analyses revealed that organ invasion at the primary surgery [hazard ratio (HR) 13.08; p = 0.005] and disease-free interval < 1 year (HR 3.64; p = 0.044) were associated with shorter overall survival. Recurrence-to-salvage interval < 6 months was associated with shorter disease-free survival (HR 2.18; p = 0.025). Concomitant organ resection was associated with a longer hospital stay: ≥ 14 days (odds ratio 21.58; p = 0.007). CONCLUSIONS: Early salvage surgery may not always be the best approach for recurrent RP WDLPS patients. Because organ invasion is rare among recurrent RP WDLPS patients and concomitant organ resection is associated with a longer hospital stay, preservation of uninvolved organs should be considered.
47 schema:genre research_article
48 schema:inLanguage en
49 schema:isAccessibleForFree false
50 schema:isPartOf N34c9659dd9c04120a469d4cc57cc08b7
51 Na588dee3b5a14299a1c848c42f6d2f91
52 sg:journal.1105545
53 schema:name Salvage Surgery for Recurrent Retroperitoneal Well-Differentiated Liposarcoma: Early Reoperation may not Provide Benefit
54 schema:pagination 2193-2200
55 schema:productId N480a7e1b4e904549a05d75b2b47bc5a4
56 N88558343e7e641ab8684391125631986
57 Na8312e2cbed24abe9a39e8257706c5ac
58 Nd6bb6344ece14c2b8ae798cbeeaf0e9d
59 Ndc0b32eaf5054cdc97016588f05fe21b
60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101382185
61 https://doi.org/10.1245/s10434-018-6417-6
62 schema:sdDatePublished 2019-04-11T11:51
63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
64 schema:sdPublisher N2102cebe7ad6463ba4014d96107610af
65 schema:url https://link.springer.com/10.1245%2Fs10434-018-6417-6
66 sgo:license sg:explorer/license/
67 sgo:sdDataset articles
68 rdf:type schema:ScholarlyArticle
69 N05af1a2ad7364ec998db4c84708930eb rdf:first sg:person.01017635105.71
70 rdf:rest N8c92588ac7d34151a30ebfa4561c5053
71 N0757b34dfa3c43fbacc6bcb9cd8cbffe rdf:first sg:person.010331373604.53
72 rdf:rest Nc84502a20b21455292ce097935e2b95e
73 N1bdf39ee16c2450ea491bb4d614f735b rdf:first sg:person.07763437315.23
74 rdf:rest N475c5d78764648d388b8940e1027f5a5
75 N2102cebe7ad6463ba4014d96107610af schema:name Springer Nature - SN SciGraph project
76 rdf:type schema:Organization
77 N344286d537e74288842294d6dc7f767a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Middle Aged
79 rdf:type schema:DefinedTerm
80 N34c9659dd9c04120a469d4cc57cc08b7 schema:issueNumber 8
81 rdf:type schema:PublicationIssue
82 N3aed00045277437781c9ee76ee30c510 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Prognosis
84 rdf:type schema:DefinedTerm
85 N463f421e43e743699c8747c70e387375 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Female
87 rdf:type schema:DefinedTerm
88 N475c5d78764648d388b8940e1027f5a5 rdf:first sg:person.01340214713.66
89 rdf:rest N9ce34d122cab46bb9d445a76d8cb56fb
90 N480a7e1b4e904549a05d75b2b47bc5a4 schema:name dimensions_id
91 schema:value pub.1101382185
92 rdf:type schema:PropertyValue
93 N4b1ed7c838164fe08fab52028ba518b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Neoplasm Invasiveness
95 rdf:type schema:DefinedTerm
96 N55be8f68af674fd0a95f956971e8c794 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Follow-Up Studies
98 rdf:type schema:DefinedTerm
99 N8142a7bb19e34609bf2151beae7a8809 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Liposarcoma
101 rdf:type schema:DefinedTerm
102 N873197a732e144f3bac1299a4f7f333b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Male
104 rdf:type schema:DefinedTerm
105 N88558343e7e641ab8684391125631986 schema:name nlm_unique_id
106 schema:value 9420840
107 rdf:type schema:PropertyValue
108 N8c92588ac7d34151a30ebfa4561c5053 rdf:first sg:person.01166770424.20
109 rdf:rest N0757b34dfa3c43fbacc6bcb9cd8cbffe
110 N900926df4a0a4f9886c089e0c575f8df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Survival Rate
112 rdf:type schema:DefinedTerm
113 N95e22d96326542e1a7bdefd003fe0431 rdf:first sg:person.010673117665.41
114 rdf:rest Nc1a3c052e6214369b26fe9b87b1c0288
115 N96a46cedca38421e8986d2117891e5b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Neoplasm Recurrence, Local
117 rdf:type schema:DefinedTerm
118 N9ce34d122cab46bb9d445a76d8cb56fb rdf:first sg:person.0730564335.43
119 rdf:rest Nedc49991bc4d48e0941182c9d071a23b
120 Na588dee3b5a14299a1c848c42f6d2f91 schema:volumeNumber 25
121 rdf:type schema:PublicationVolume
122 Na8312e2cbed24abe9a39e8257706c5ac schema:name pubmed_id
123 schema:value 29520652
124 rdf:type schema:PropertyValue
125 Nb6a77032a3c341928aa56ed1a297d4a1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Length of Stay
127 rdf:type schema:DefinedTerm
128 Nb9bac550ed094a4b8817161066254388 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Postoperative Complications
130 rdf:type schema:DefinedTerm
131 Nbb4a8e532ff34438ac65ca07f0c193ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Patient Selection
133 rdf:type schema:DefinedTerm
134 Nbd0bea23006c4219ab4c676d87d574b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Retrospective Studies
136 rdf:type schema:DefinedTerm
137 Nc1a3c052e6214369b26fe9b87b1c0288 rdf:first sg:person.01006236215.10
138 rdf:rest N05af1a2ad7364ec998db4c84708930eb
139 Nc84502a20b21455292ce097935e2b95e rdf:first sg:person.01352620562.07
140 rdf:rest N1bdf39ee16c2450ea491bb4d614f735b
141 Nd6bb6344ece14c2b8ae798cbeeaf0e9d schema:name doi
142 schema:value 10.1245/s10434-018-6417-6
143 rdf:type schema:PropertyValue
144 Nd73964df060249e3b136d2cc20f37ba9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Second-Look Surgery
146 rdf:type schema:DefinedTerm
147 Nda1db6ecf40f45dd877463dd60c034fa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Reoperation
149 rdf:type schema:DefinedTerm
150 Ndc0b32eaf5054cdc97016588f05fe21b schema:name readcube_id
151 schema:value 236005223d383a1f62d85d7be7f5f4edcf790e54fdc70f54b81f199c563387dc
152 rdf:type schema:PropertyValue
153 Nedc49991bc4d48e0941182c9d071a23b rdf:first sg:person.0634233332.35
154 rdf:rest rdf:nil
155 Nef56417253d1403fb0d3607a24495f57 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Retroperitoneal Neoplasms
157 rdf:type schema:DefinedTerm
158 Nfc5a716b605f42db949ca61429667761 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Salvage Therapy
160 rdf:type schema:DefinedTerm
161 Nfd66bc56a0024faa9a25656b9d207778 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Humans
163 rdf:type schema:DefinedTerm
164 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
165 schema:name Medical and Health Sciences
166 rdf:type schema:DefinedTerm
167 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
168 schema:name Oncology and Carcinogenesis
169 rdf:type schema:DefinedTerm
170 sg:grant.2438826 http://pending.schema.org/fundedItem sg:pub.10.1245/s10434-018-6417-6
171 rdf:type schema:MonetaryGrant
172 sg:journal.1105545 schema:issn 1068-9265
173 1534-4681
174 schema:name Annals of Surgical Oncology
175 rdf:type schema:Periodical
176 sg:person.01006236215.10 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
177 schema:familyName Roland
178 schema:givenName Christina L.
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006236215.10
180 rdf:type schema:Person
181 sg:person.01017635105.71 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
182 schema:familyName Torres
183 schema:givenName Keila E.
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017635105.71
185 rdf:type schema:Person
186 sg:person.010331373604.53 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
187 schema:familyName Wang
188 schema:givenName Wei-Lien
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010331373604.53
190 rdf:type schema:Person
191 sg:person.010673117665.41 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
192 schema:familyName Ikoma
193 schema:givenName Naruhiko
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010673117665.41
195 rdf:type schema:Person
196 sg:person.01166770424.20 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
197 schema:familyName Chiang
198 schema:givenName Yi-Ju
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01166770424.20
200 rdf:type schema:Person
201 sg:person.01340214713.66 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
202 schema:familyName Hunt
203 schema:givenName Kelly K.
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340214713.66
205 rdf:type schema:Person
206 sg:person.01352620562.07 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
207 schema:familyName Somaiah
208 schema:givenName Neeta
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01352620562.07
210 rdf:type schema:Person
211 sg:person.0634233332.35 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
212 schema:familyName Feig
213 schema:givenName Barry W.
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634233332.35
215 rdf:type schema:Person
216 sg:person.0730564335.43 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
217 schema:familyName Cormier
218 schema:givenName Janice N.
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730564335.43
220 rdf:type schema:Person
221 sg:person.07763437315.23 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
222 schema:familyName Mann
223 schema:givenName Gary N.
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07763437315.23
225 rdf:type schema:Person
226 sg:pub.10.1245/s10434-008-0250-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008547685
227 https://doi.org/10.1245/s10434-008-0250-2
228 rdf:type schema:CreativeWork
229 sg:pub.10.1245/s10434-014-4130-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040236094
230 https://doi.org/10.1245/s10434-014-4130-7
231 rdf:type schema:CreativeWork
232 sg:pub.10.1245/s10434-016-5344-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021317320
233 https://doi.org/10.1245/s10434-016-5344-7
234 rdf:type schema:CreativeWork
235 sg:pub.10.1245/s10434-016-5523-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013821787
236 https://doi.org/10.1245/s10434-016-5523-6
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1002/cncr.30572 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083523188
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/j.jamcollsurg.2009.12.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023610388
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/j.jss.2010.07.056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011782026
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1016/j.yasu.2015.04.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009194775
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1053/ejso.2001.1166 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025165333
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1097/00000658-199809000-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060134859
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1097/01.sla.0000108670.31446.54 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008133880
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1097/01.sla.0000133083.54934.ae schema:sameAs https://app.dimensions.ai/details/publication/pub.1024049438
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1097/sla.0000000000001149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022350348
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1097/sla.0000000000001447 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014206895
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1097/sla.0b013e3181928f2f schema:sameAs https://app.dimensions.ai/details/publication/pub.1002112623
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1097/sla.0b013e3181b2468b schema:sameAs https://app.dimensions.ai/details/publication/pub.1023369756
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1200/jco.2008.17.8871 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040189711
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1200/jco.2008.18.0802 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017397932
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1200/jco.2008.18.7138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022382005
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1308/003588410x12771863936729 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029287410
269 rdf:type schema:CreativeWork
270 https://doi.org/10.18632/oncotarget.16345 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091756616
271 rdf:type schema:CreativeWork
272 https://doi.org/10.3322/canjclin.56.5.282 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049471116
273 rdf:type schema:CreativeWork
274 https://www.grid.ac/institutes/grid.240145.6 schema:alternateName The University of Texas MD Anderson Cancer Center
275 schema:name Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
276 Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
277 Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
278 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...