Short- and Long-Term Outcomes After Gastrectomy in Elderly Gastric Cancer Patients View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-02

AUTHORS

Jun-Young Yang, Hyuk-Joon Lee, Tae Han Kim, Yeon-Ju Huh, Young-Gil Son, Ji-Ho Park, Hye Seong Ahn, Yun-Suhk Suh, Seong-Ho Kong, Han-Kwang Yang

ABSTRACT

BACKGROUND: The number of elderly patients undergoing gastric cancer surgery has recently increased. We therefore evaluated the short- and long-term outcomes of elderly patients after curative gastrectomy. METHODS: Overall, 824 patients were included in this retrospective study, which comprised of a non-elderly group (60-64 years; n = 558), an early-elderly group (75-79 years; n = 198), and a late-elderly group (≥80 years; n = 68) who underwent curative gastrectomy for gastric cancer between 2005 and 2009. Postoperative complications, according to the Clavien-Dindo classification, and survival of both elderly groups were compared with the non-elderly group. Postoperative life expectancy of the late-elderly group was compared with the corresponding aged general population. RESULTS: Overall and severe (grade III or higher) complications in the early-elderly group were comparable with the non-elderly group; however, those in the late-elderly group were significantly more common than in the non-elderly group (p = 0.013 and p = 0.043, respectively). Multivariable analysis revealed that age ≥80 years was an independent risk factor for severe complications (hazard ratio 3.02, 95 % confidence interval 1.12-8.17; p = 0.029), and the disease-specific survivals of both elderly groups were comparable with the non-elderly group in all TNM stages. Postoperative life expectancy of late-elderly patients eliminating death from recurrence was comparable with the corresponding aged general population eliminating death from gastric cancer. CONCLUSIONS: Gastric cancer surgery in elderly patients aged ≥80 years achieves reasonable long-term survival despite the increased risk of severe complications. More... »

PAGES

469-477

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1245/s10434-016-5482-y

    DOI

    http://dx.doi.org/10.1245/s10434-016-5482-y

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1051865731

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27489057


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