A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma: Results from ACOSOG ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-08

AUTHORS

Rache M. Simmons, Karla V. Ballman, Charles Cox, Ned Carp, Jennifer Sabol, Rosa F. Hwang, Deanna Attai, Michael Sabel, David Nathanson, Andrew Kenler, Linsey Gold, Cary Kaufman, Linda Han, Aaron Bleznak, J. Stanley Smith, Dennis Holmes, Bruno Fornage, Carisa Le-Petross, Syed Hoda, Linda McCall, Kelly K. Hunt, on behalf of the ACOSOG investigators

ABSTRACT

BACKGROUND: Cryoablation is a well-established technique to treat fibroadenomas. Pilot studies suggest this could be an effective non-surgical treatment for breast cancer. American College of Surgeons Oncology Group Z1072 is a phase II trial exploring the effectiveness of cryoablation in the treatment of breast cancers. METHODS: The primary endpoint of Z1072 was the rate of complete tumor ablation, defined as no remaining invasive breast cancer (IBC) or ductal carcinoma in situ (DCIS) on pathologic examination of the targeted lesion. A secondary objective was to evaluate the negative predictive value of magnetic resonance imaging (MRI) to determine residual IBC or DCIS. Eligible patients included those with unifocal invasive ductal breast cancer ≤2 cm, with <25 % intraductal component and tumor enhancement on MRI. A total of 19 centers contributed 99 patients, of which 86 patients (87 breast cancers) were evaluable for data analysis. RESULTS: Final pathology results, regardless of whether residual IBC/DCIS was in the targeted ablation zone or elsewhere in the breast, showed successful ablation in 66/87 (75.9 %) cancers. The 90 % confidence interval for the estimate of successful cryoablation was 67.1-83.2, with the one-sided lower-sided 90 % CI of 69.0. The negative predictive value of MRI was 81.2 % (90 % CI 71.4-88.8). When multifocal disease outside of the targeted cryoablation zone was not defined as an ablation failure, 80/87 (92 %) of the treated cancers had a successful cryoablation. CONCLUSION: Further studies with modifications on the Z1072 protocol could be considered to evaluate the role for cryoablation as a non-surgical treatment of early-stage breast cancer. More... »

PAGES

2438-2445

Identifiers

URI

http://scigraph.springernature.com/pub.10.1245/s10434-016-5275-3

DOI

http://dx.doi.org/10.1245/s10434-016-5275-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005558557

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27221361


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Breast Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma, Ductal, Breast", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cryosurgery", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Invasiveness", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Predictive Value of Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "NewYork\u2013Presbyterian Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413734.6", 
          "name": [
            "Department of Surgery, Iris Cantor Women\u2019s Health Center, The New York Presbyterian Hospital, Joan and Sanford Weill Medical College of Cornell University, New York, NY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Simmons", 
        "givenName": "Rache M.", 
        "id": "sg:person.01023044764.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023044764.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mayo Clinic", 
          "id": "https://www.grid.ac/institutes/grid.66875.3a", 
          "name": [
            "Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ballman", 
        "givenName": "Karla V.", 
        "id": "sg:person.012313410037.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012313410037.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of South Florida", 
          "id": "https://www.grid.ac/institutes/grid.170693.a", 
          "name": [
            "Department of Surgery, University of South Florida, Tampa, FL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cox", 
        "givenName": "Charles", 
        "id": "sg:person.010551343062.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010551343062.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Lankenau Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.415792.c", 
          "name": [
            "Department of Surgery, Lankenau Medical Center, Wynnewood, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Carp", 
        "givenName": "Ned", 
        "id": "sg:person.0733710574.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733710574.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Lankenau Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.415792.c", 
          "name": [
            "Department of Surgery, Lankenau Medical Center, Wynnewood, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sabol", 
        "givenName": "Jennifer", 
        "id": "sg:person.012631226031.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012631226031.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Breast Surgical Oncology, MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hwang", 
        "givenName": "Rosa F.", 
        "id": "sg:person.0622317230.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622317230.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Providence Saint Joseph Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.490448.5", 
          "name": [
            "Department of Surgery, Providence Saint Joseph Medical Center, Burbank, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Attai", 
        "givenName": "Deanna", 
        "id": "sg:person.01101247521.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101247521.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Michigan Medicine", 
          "id": "https://www.grid.ac/institutes/grid.412590.b", 
          "name": [
            "Department of Surgery, University of Michigan Hospital, Ann Arbor, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sabel", 
        "givenName": "Michael", 
        "id": "sg:person.0757207556.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757207556.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Henry Ford Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413103.4", 
          "name": [
            "Department of Surgery, Henry Ford Hospital, Detroit, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nathanson", 
        "givenName": "David", 
        "id": "sg:person.0675457574.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675457574.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bridgeport Hospital", 
          "id": "https://www.grid.ac/institutes/grid.414600.7", 
          "name": [
            "Department of Surgery, Bridgeport Hospital, Bridgeport, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kenler", 
        "givenName": "Andrew", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Genesys Regional Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.415497.a", 
          "name": [
            "Department of Surgery, Genesys Regional Medical Center, Grand Blanc, MI, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gold", 
        "givenName": "Linsey", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Surgery, Bellingham Breast Center, Bellingham, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kaufman", 
        "givenName": "Cary", 
        "id": "sg:person.0731205154.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731205154.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Indiana University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411570.6", 
          "name": [
            "Department of Surgery, Indiana University Hospital, Indianapolis, IN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Han", 
        "givenName": "Linda", 
        "id": "sg:person.0671046677.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671046677.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Lehigh Valley Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413625.7", 
          "name": [
            "Department of Surgery, Lehigh Valley Hospital, Allentown, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bleznak", 
        "givenName": "Aaron", 
        "id": "sg:person.01154647305.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154647305.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Penn State Milton S. Hershey Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.240473.6", 
          "name": [
            "Department of Surgery, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stanley Smith", 
        "givenName": "J.", 
        "id": "sg:person.0752670330.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0752670330.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Southern California", 
          "id": "https://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Department of Surgery, University of Southern California, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Holmes", 
        "givenName": "Dennis", 
        "id": "sg:person.01301645555.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301645555.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Diagnostic Radiology, MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fornage", 
        "givenName": "Bruno", 
        "id": "sg:person.01143453337.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143453337.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Diagnostic Radiology, MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Le-Petross", 
        "givenName": "Carisa", 
        "id": "sg:person.01130053440.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130053440.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cornell University", 
          "id": "https://www.grid.ac/institutes/grid.5386.8", 
          "name": [
            "Department of Pathology, Weill Cornell Medical College, New York, NY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hoda", 
        "givenName": "Syed", 
        "id": "sg:person.01321527712.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321527712.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Duke University", 
          "id": "https://www.grid.ac/institutes/grid.26009.3d", 
          "name": [
            "Alliance Statistics and Data Center, Duke University, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McCall", 
        "givenName": "Linda", 
        "id": "sg:person.0605530047.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605530047.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Breast Surgical Oncology, MD Anderson Cancer Center, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hunt", 
        "givenName": "Kelly K.", 
        "id": "sg:person.01340214713.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340214713.66"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "on behalf of the ACOSOG investigators", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1080/0265673021000017073", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000880537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(20011015)92:8<2036::aid-cncr1542>3.0.co;2-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001087029"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiol.2311030651", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001704247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02573866", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005043764", 
          "https://doi.org/10.1007/bf02573866"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02573866", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005043764", 
          "https://doi.org/10.1007/bf02573866"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.134.10.1064", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005154371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00130404-200203000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006294557"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00130404-200203000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006294557"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9610(03)00061-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006701779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9610(03)00061-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006701779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiol.2281012163", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012467526"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9610(02)01010-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014472530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9610(02)01010-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014472530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/aso.2004.08.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016212170", 
          "https://doi.org/10.1245/aso.2004.08.003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/aso.2004.08.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016212170", 
          "https://doi.org/10.1245/aso.2004.08.003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.11642", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016650786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(19870215)59:4<675::aid-cncr2820590402>3.0.co;2-u", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021175227"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3233/bd-2001-13109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021197341"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1117/12.351004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024956327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9610(02)00942-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032440695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1075-122x.2005.21700.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037122347"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1075-122x.2005.21700.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037122347"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9610(01)00732-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039325577"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.1989.01410010043009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042691397"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.135.11.1345", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053385519"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074961220", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-08", 
    "datePublishedReg": "2016-08-01", 
    "description": "BACKGROUND: Cryoablation is a well-established technique to treat fibroadenomas. Pilot studies suggest this could be an effective non-surgical treatment for breast cancer. American College of Surgeons Oncology Group Z1072 is a phase II trial exploring the effectiveness of cryoablation in the treatment of breast cancers.\nMETHODS: The primary endpoint of Z1072 was the rate of complete tumor ablation, defined as no remaining invasive breast cancer (IBC) or ductal carcinoma in situ (DCIS) on pathologic examination of the targeted lesion. A secondary objective was to evaluate the negative predictive value of magnetic resonance imaging (MRI) to determine residual IBC or DCIS. Eligible patients included those with unifocal invasive ductal breast cancer \u22642\u00a0cm, with <25\u00a0% intraductal component and tumor enhancement on MRI. A total of 19 centers contributed 99 patients, of which 86 patients (87 breast cancers) were evaluable for data analysis.\nRESULTS: Final pathology results, regardless of whether residual IBC/DCIS was in the targeted ablation zone or elsewhere in the breast, showed successful ablation in 66/87 (75.9\u00a0%) cancers. The 90\u00a0% confidence interval for the estimate of successful cryoablation was 67.1-83.2, with the one-sided lower-sided 90\u00a0% CI of 69.0. The negative predictive value of MRI was 81.2\u00a0% (90\u00a0% CI 71.4-88.8). When multifocal disease outside of the targeted cryoablation zone was not defined as an ablation failure, 80/87 (92\u00a0%) of the treated cancers had a successful cryoablation.\nCONCLUSION: Further studies with modifications on the Z1072 protocol could be considered to evaluate the role for cryoablation as a non-surgical treatment of early-stage breast cancer.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1245/s10434-016-5275-3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.3535136", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3535792", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3535030", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1105545", 
        "issn": [
          "1068-9265", 
          "1534-4681"
        ], 
        "name": "Annals of Surgical Oncology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "8", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "23"
      }
    ], 
    "name": "A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma: Results from ACOSOG (Alliance) Z1072", 
    "pagination": "2438-2445", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "1a7bb8a7bbf8c231ff3cd0d33000f67b0206bc9accc418386caf3a46adfd9d0f"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27221361"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9420840"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1245/s10434-016-5275-3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1005558557"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1245/s10434-016-5275-3", 
      "https://app.dimensions.ai/details/publication/pub.1005558557"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T11:35", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000358_0000000358/records_127426_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1245/s10434-016-5275-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1245/s10434-016-5275-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1245/s10434-016-5275-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1245/s10434-016-5275-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1245/s10434-016-5275-3'


 

This table displays all metadata directly associated to this object as RDF triples.

378 TRIPLES      21 PREDICATES      62 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1245/s10434-016-5275-3 schema:about N0044e13c02e04700b120509e11c05c7f
2 N14250ec3da2d4d318c79aecf748a8690
3 N23f8b470ac484f0baf6259264426f288
4 N27c5e99fdb274696b2d545b0098a016b
5 N4857587b84eb48049b457a655307f25b
6 N53d51de9e3fe4155a272267ed4add73a
7 N604e9eff803447e887edbdb6503b1c45
8 N698bb0fac8cb4ff48bfe9abe230069cf
9 N6db7d7e5633c42a496bf7fccd05fc850
10 N710487cc54f2425aae162c73952ad4de
11 Ndf552f7ad03143dc803fd2c606850c4d
12 Nec841865ba7a4a8e9e60d39e795ef649
13 Nf3e079ce669549af8cf536fa62319a5a
14 anzsrc-for:11
15 anzsrc-for:1112
16 schema:author Nc0814008980f4024814e86c04acbbeb3
17 schema:citation sg:pub.10.1007/bf02573866
18 sg:pub.10.1245/aso.2004.08.003
19 https://app.dimensions.ai/details/publication/pub.1074961220
20 https://doi.org/10.1001/archsurg.134.10.1064
21 https://doi.org/10.1001/archsurg.135.11.1345
22 https://doi.org/10.1001/archsurg.1989.01410010043009
23 https://doi.org/10.1002/1097-0142(19870215)59:4<675::aid-cncr2820590402>3.0.co;2-u
24 https://doi.org/10.1002/1097-0142(20011015)92:8<2036::aid-cncr1542>3.0.co;2-w
25 https://doi.org/10.1002/cncr.11642
26 https://doi.org/10.1016/s0002-9610(01)00732-2
27 https://doi.org/10.1016/s0002-9610(02)00942-x
28 https://doi.org/10.1016/s0002-9610(02)01010-3
29 https://doi.org/10.1016/s0002-9610(03)00061-8
30 https://doi.org/10.1080/0265673021000017073
31 https://doi.org/10.1097/00130404-200203000-00011
32 https://doi.org/10.1111/j.1075-122x.2005.21700.x
33 https://doi.org/10.1117/12.351004
34 https://doi.org/10.1148/radiol.2281012163
35 https://doi.org/10.1148/radiol.2311030651
36 https://doi.org/10.3233/bd-2001-13109
37 schema:datePublished 2016-08
38 schema:datePublishedReg 2016-08-01
39 schema:description BACKGROUND: Cryoablation is a well-established technique to treat fibroadenomas. Pilot studies suggest this could be an effective non-surgical treatment for breast cancer. American College of Surgeons Oncology Group Z1072 is a phase II trial exploring the effectiveness of cryoablation in the treatment of breast cancers. METHODS: The primary endpoint of Z1072 was the rate of complete tumor ablation, defined as no remaining invasive breast cancer (IBC) or ductal carcinoma in situ (DCIS) on pathologic examination of the targeted lesion. A secondary objective was to evaluate the negative predictive value of magnetic resonance imaging (MRI) to determine residual IBC or DCIS. Eligible patients included those with unifocal invasive ductal breast cancer ≤2 cm, with <25 % intraductal component and tumor enhancement on MRI. A total of 19 centers contributed 99 patients, of which 86 patients (87 breast cancers) were evaluable for data analysis. RESULTS: Final pathology results, regardless of whether residual IBC/DCIS was in the targeted ablation zone or elsewhere in the breast, showed successful ablation in 66/87 (75.9 %) cancers. The 90 % confidence interval for the estimate of successful cryoablation was 67.1-83.2, with the one-sided lower-sided 90 % CI of 69.0. The negative predictive value of MRI was 81.2 % (90 % CI 71.4-88.8). When multifocal disease outside of the targeted cryoablation zone was not defined as an ablation failure, 80/87 (92 %) of the treated cancers had a successful cryoablation. CONCLUSION: Further studies with modifications on the Z1072 protocol could be considered to evaluate the role for cryoablation as a non-surgical treatment of early-stage breast cancer.
40 schema:genre research_article
41 schema:inLanguage en
42 schema:isAccessibleForFree true
43 schema:isPartOf N78534f2917044b0588020f85bc44d9f1
44 Nb29abb1f074e44488135b5cc0024895a
45 sg:journal.1105545
46 schema:name A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma: Results from ACOSOG (Alliance) Z1072
47 schema:pagination 2438-2445
48 schema:productId N41573bba25424822926c926a7d23d5f3
49 N68b1903045634e4e9bb948a513ec7c5a
50 N81ce578bcadb43dcbeaa750acc24a20f
51 Nb03a59152cd94e07b3449120e7dee00d
52 Nfcfcd4615ff8470ea94e66c308677a99
53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005558557
54 https://doi.org/10.1245/s10434-016-5275-3
55 schema:sdDatePublished 2019-04-11T11:35
56 schema:sdLicense https://scigraph.springernature.com/explorer/license/
57 schema:sdPublisher N2cf6c71336a34a5cb06952321c2ad09b
58 schema:url http://link.springer.com/10.1245/s10434-016-5275-3
59 sgo:license sg:explorer/license/
60 sgo:sdDataset articles
61 rdf:type schema:ScholarlyArticle
62 N0044e13c02e04700b120509e11c05c7f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
63 schema:name Magnetic Resonance Imaging
64 rdf:type schema:DefinedTerm
65 N0125e367b14642abaa7182db75c1cc40 rdf:first sg:person.01143453337.10
66 rdf:rest N55a3b24fe2064f9a843754bb38df4729
67 N04a34d76a92c4343ad4ad29cb876274e rdf:first sg:person.012631226031.24
68 rdf:rest N560a7725c9af44e89a84a07cdb3c28e6
69 N0806df859dcf423da44d6a51a11febaf schema:affiliation https://www.grid.ac/institutes/grid.414600.7
70 schema:familyName Kenler
71 schema:givenName Andrew
72 rdf:type schema:Person
73 N14250ec3da2d4d318c79aecf748a8690 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Treatment Outcome
75 rdf:type schema:DefinedTerm
76 N20f83612f3054d3f8cf506c8e0643ecc rdf:first sg:person.0671046677.24
77 rdf:rest N5003a7107ea743868a0949002b1962fe
78 N23100fbc2f6a4741a7f957ccdc64fd33 rdf:first sg:person.01301645555.23
79 rdf:rest N0125e367b14642abaa7182db75c1cc40
80 N23f8b470ac484f0baf6259264426f288 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Aged
82 rdf:type schema:DefinedTerm
83 N27c5e99fdb274696b2d545b0098a016b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Neoplasm Invasiveness
85 rdf:type schema:DefinedTerm
86 N2cf6c71336a34a5cb06952321c2ad09b schema:name Springer Nature - SN SciGraph project
87 rdf:type schema:Organization
88 N41573bba25424822926c926a7d23d5f3 schema:name doi
89 schema:value 10.1245/s10434-016-5275-3
90 rdf:type schema:PropertyValue
91 N48057d31303a4c3494c9ee603e973853 rdf:first sg:person.0605530047.72
92 rdf:rest Nb9bd494ac39d4e35a6319d0842b2a878
93 N4857587b84eb48049b457a655307f25b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Carcinoma, Ductal, Breast
95 rdf:type schema:DefinedTerm
96 N5003a7107ea743868a0949002b1962fe rdf:first sg:person.01154647305.54
97 rdf:rest Nd23cc1495a134d05a165c1f6b0595d5f
98 N53d51de9e3fe4155a272267ed4add73a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Middle Aged
100 rdf:type schema:DefinedTerm
101 N55a3b24fe2064f9a843754bb38df4729 rdf:first sg:person.01130053440.74
102 rdf:rest Nb32fddfbf32941108336dd03367149d1
103 N560a7725c9af44e89a84a07cdb3c28e6 rdf:first sg:person.0622317230.72
104 rdf:rest Nc99dfbfc311541b4a952b3442fb33708
105 N592d0b5799ea42ca95420736a72e6013 rdf:first sg:person.010551343062.17
106 rdf:rest Nb33f04f474734f97974b475baf6ab27f
107 N604e9eff803447e887edbdb6503b1c45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Aged, 80 and over
109 rdf:type schema:DefinedTerm
110 N68b1903045634e4e9bb948a513ec7c5a schema:name pubmed_id
111 schema:value 27221361
112 rdf:type schema:PropertyValue
113 N698bb0fac8cb4ff48bfe9abe230069cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Breast Neoplasms
115 rdf:type schema:DefinedTerm
116 N6db7d7e5633c42a496bf7fccd05fc850 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Humans
118 rdf:type schema:DefinedTerm
119 N710487cc54f2425aae162c73952ad4de schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Adult
121 rdf:type schema:DefinedTerm
122 N72f4fc7fe47c47dba3f8d0394d1747d8 rdf:first sg:person.012313410037.83
123 rdf:rest N592d0b5799ea42ca95420736a72e6013
124 N77be9ba7eeb54136b477efedbd732db7 rdf:first sg:person.0731205154.04
125 rdf:rest N20f83612f3054d3f8cf506c8e0643ecc
126 N78534f2917044b0588020f85bc44d9f1 schema:issueNumber 8
127 rdf:type schema:PublicationIssue
128 N81ce578bcadb43dcbeaa750acc24a20f schema:name dimensions_id
129 schema:value pub.1005558557
130 rdf:type schema:PropertyValue
131 N866de7dd905a4ec983a09b54aebec0d8 rdf:first Nc434d6d1f5f24f518b1277db5efd27f0
132 rdf:rest rdf:nil
133 Nb03a59152cd94e07b3449120e7dee00d schema:name readcube_id
134 schema:value 1a7bb8a7bbf8c231ff3cd0d33000f67b0206bc9accc418386caf3a46adfd9d0f
135 rdf:type schema:PropertyValue
136 Nb29abb1f074e44488135b5cc0024895a schema:volumeNumber 23
137 rdf:type schema:PublicationVolume
138 Nb32fddfbf32941108336dd03367149d1 rdf:first sg:person.01321527712.46
139 rdf:rest N48057d31303a4c3494c9ee603e973853
140 Nb33f04f474734f97974b475baf6ab27f rdf:first sg:person.0733710574.20
141 rdf:rest N04a34d76a92c4343ad4ad29cb876274e
142 Nb9bd494ac39d4e35a6319d0842b2a878 rdf:first sg:person.01340214713.66
143 rdf:rest N866de7dd905a4ec983a09b54aebec0d8
144 Nba97f18f1abf4aa6a3563cf537301ac0 rdf:first sg:person.0757207556.48
145 rdf:rest Ndd24bd042456463ca0b42ed9a979f4ae
146 Nc0814008980f4024814e86c04acbbeb3 rdf:first sg:person.01023044764.00
147 rdf:rest N72f4fc7fe47c47dba3f8d0394d1747d8
148 Nc434d6d1f5f24f518b1277db5efd27f0 schema:familyName on behalf of the ACOSOG investigators
149 rdf:type schema:Person
150 Nc51774986ccd4a21bc4c9321039118fd schema:affiliation https://www.grid.ac/institutes/grid.415497.a
151 schema:familyName Gold
152 schema:givenName Linsey
153 rdf:type schema:Person
154 Nc6f610de514a4157a3a802b68a34b94e schema:name Department of Surgery, Bellingham Breast Center, Bellingham, WA, USA
155 rdf:type schema:Organization
156 Nc99dfbfc311541b4a952b3442fb33708 rdf:first sg:person.01101247521.90
157 rdf:rest Nba97f18f1abf4aa6a3563cf537301ac0
158 Nd23cc1495a134d05a165c1f6b0595d5f rdf:first sg:person.0752670330.27
159 rdf:rest N23100fbc2f6a4741a7f957ccdc64fd33
160 Nd9868a37189c46348961d3aa9124afed rdf:first N0806df859dcf423da44d6a51a11febaf
161 rdf:rest Nffc1d68b045f43d5b17cba497e580b54
162 Ndd24bd042456463ca0b42ed9a979f4ae rdf:first sg:person.0675457574.10
163 rdf:rest Nd9868a37189c46348961d3aa9124afed
164 Ndf552f7ad03143dc803fd2c606850c4d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Cryosurgery
166 rdf:type schema:DefinedTerm
167 Nec841865ba7a4a8e9e60d39e795ef649 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Predictive Value of Tests
169 rdf:type schema:DefinedTerm
170 Nf3e079ce669549af8cf536fa62319a5a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Female
172 rdf:type schema:DefinedTerm
173 Nfcfcd4615ff8470ea94e66c308677a99 schema:name nlm_unique_id
174 schema:value 9420840
175 rdf:type schema:PropertyValue
176 Nffc1d68b045f43d5b17cba497e580b54 rdf:first Nc51774986ccd4a21bc4c9321039118fd
177 rdf:rest N77be9ba7eeb54136b477efedbd732db7
178 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
179 schema:name Medical and Health Sciences
180 rdf:type schema:DefinedTerm
181 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
182 schema:name Oncology and Carcinogenesis
183 rdf:type schema:DefinedTerm
184 sg:grant.3535030 http://pending.schema.org/fundedItem sg:pub.10.1245/s10434-016-5275-3
185 rdf:type schema:MonetaryGrant
186 sg:grant.3535136 http://pending.schema.org/fundedItem sg:pub.10.1245/s10434-016-5275-3
187 rdf:type schema:MonetaryGrant
188 sg:grant.3535792 http://pending.schema.org/fundedItem sg:pub.10.1245/s10434-016-5275-3
189 rdf:type schema:MonetaryGrant
190 sg:journal.1105545 schema:issn 1068-9265
191 1534-4681
192 schema:name Annals of Surgical Oncology
193 rdf:type schema:Periodical
194 sg:person.01023044764.00 schema:affiliation https://www.grid.ac/institutes/grid.413734.6
195 schema:familyName Simmons
196 schema:givenName Rache M.
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023044764.00
198 rdf:type schema:Person
199 sg:person.010551343062.17 schema:affiliation https://www.grid.ac/institutes/grid.170693.a
200 schema:familyName Cox
201 schema:givenName Charles
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010551343062.17
203 rdf:type schema:Person
204 sg:person.01101247521.90 schema:affiliation https://www.grid.ac/institutes/grid.490448.5
205 schema:familyName Attai
206 schema:givenName Deanna
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101247521.90
208 rdf:type schema:Person
209 sg:person.01130053440.74 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
210 schema:familyName Le-Petross
211 schema:givenName Carisa
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130053440.74
213 rdf:type schema:Person
214 sg:person.01143453337.10 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
215 schema:familyName Fornage
216 schema:givenName Bruno
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143453337.10
218 rdf:type schema:Person
219 sg:person.01154647305.54 schema:affiliation https://www.grid.ac/institutes/grid.413625.7
220 schema:familyName Bleznak
221 schema:givenName Aaron
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154647305.54
223 rdf:type schema:Person
224 sg:person.012313410037.83 schema:affiliation https://www.grid.ac/institutes/grid.66875.3a
225 schema:familyName Ballman
226 schema:givenName Karla V.
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012313410037.83
228 rdf:type schema:Person
229 sg:person.012631226031.24 schema:affiliation https://www.grid.ac/institutes/grid.415792.c
230 schema:familyName Sabol
231 schema:givenName Jennifer
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012631226031.24
233 rdf:type schema:Person
234 sg:person.01301645555.23 schema:affiliation https://www.grid.ac/institutes/grid.42505.36
235 schema:familyName Holmes
236 schema:givenName Dennis
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301645555.23
238 rdf:type schema:Person
239 sg:person.01321527712.46 schema:affiliation https://www.grid.ac/institutes/grid.5386.8
240 schema:familyName Hoda
241 schema:givenName Syed
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321527712.46
243 rdf:type schema:Person
244 sg:person.01340214713.66 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
245 schema:familyName Hunt
246 schema:givenName Kelly K.
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340214713.66
248 rdf:type schema:Person
249 sg:person.0605530047.72 schema:affiliation https://www.grid.ac/institutes/grid.26009.3d
250 schema:familyName McCall
251 schema:givenName Linda
252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605530047.72
253 rdf:type schema:Person
254 sg:person.0622317230.72 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
255 schema:familyName Hwang
256 schema:givenName Rosa F.
257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622317230.72
258 rdf:type schema:Person
259 sg:person.0671046677.24 schema:affiliation https://www.grid.ac/institutes/grid.411570.6
260 schema:familyName Han
261 schema:givenName Linda
262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671046677.24
263 rdf:type schema:Person
264 sg:person.0675457574.10 schema:affiliation https://www.grid.ac/institutes/grid.413103.4
265 schema:familyName Nathanson
266 schema:givenName David
267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675457574.10
268 rdf:type schema:Person
269 sg:person.0731205154.04 schema:affiliation Nc6f610de514a4157a3a802b68a34b94e
270 schema:familyName Kaufman
271 schema:givenName Cary
272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731205154.04
273 rdf:type schema:Person
274 sg:person.0733710574.20 schema:affiliation https://www.grid.ac/institutes/grid.415792.c
275 schema:familyName Carp
276 schema:givenName Ned
277 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733710574.20
278 rdf:type schema:Person
279 sg:person.0752670330.27 schema:affiliation https://www.grid.ac/institutes/grid.240473.6
280 schema:familyName Stanley Smith
281 schema:givenName J.
282 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0752670330.27
283 rdf:type schema:Person
284 sg:person.0757207556.48 schema:affiliation https://www.grid.ac/institutes/grid.412590.b
285 schema:familyName Sabel
286 schema:givenName Michael
287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757207556.48
288 rdf:type schema:Person
289 sg:pub.10.1007/bf02573866 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005043764
290 https://doi.org/10.1007/bf02573866
291 rdf:type schema:CreativeWork
292 sg:pub.10.1245/aso.2004.08.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016212170
293 https://doi.org/10.1245/aso.2004.08.003
294 rdf:type schema:CreativeWork
295 https://app.dimensions.ai/details/publication/pub.1074961220 schema:CreativeWork
296 https://doi.org/10.1001/archsurg.134.10.1064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005154371
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1001/archsurg.135.11.1345 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053385519
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1001/archsurg.1989.01410010043009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042691397
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1002/1097-0142(19870215)59:4<675::aid-cncr2820590402>3.0.co;2-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1021175227
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1002/1097-0142(20011015)92:8<2036::aid-cncr1542>3.0.co;2-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1001087029
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1002/cncr.11642 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016650786
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1016/s0002-9610(01)00732-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039325577
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1016/s0002-9610(02)00942-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032440695
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1016/s0002-9610(02)01010-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014472530
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1016/s0002-9610(03)00061-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006701779
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1080/0265673021000017073 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000880537
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1097/00130404-200203000-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006294557
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1111/j.1075-122x.2005.21700.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037122347
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1117/12.351004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024956327
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1148/radiol.2281012163 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012467526
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1148/radiol.2311030651 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001704247
327 rdf:type schema:CreativeWork
328 https://doi.org/10.3233/bd-2001-13109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021197341
329 rdf:type schema:CreativeWork
330 https://www.grid.ac/institutes/grid.170693.a schema:alternateName University of South Florida
331 schema:name Department of Surgery, University of South Florida, Tampa, FL, USA
332 rdf:type schema:Organization
333 https://www.grid.ac/institutes/grid.240145.6 schema:alternateName The University of Texas MD Anderson Cancer Center
334 schema:name Department of Breast Surgical Oncology, MD Anderson Cancer Center, Houston, TX, USA
335 Department of Diagnostic Radiology, MD Anderson Cancer Center, Houston, TX, USA
336 rdf:type schema:Organization
337 https://www.grid.ac/institutes/grid.240473.6 schema:alternateName Penn State Milton S. Hershey Medical Center
338 schema:name Department of Surgery, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA
339 rdf:type schema:Organization
340 https://www.grid.ac/institutes/grid.26009.3d schema:alternateName Duke University
341 schema:name Alliance Statistics and Data Center, Duke University, Durham, NC, USA
342 rdf:type schema:Organization
343 https://www.grid.ac/institutes/grid.411570.6 schema:alternateName Indiana University Hospital
344 schema:name Department of Surgery, Indiana University Hospital, Indianapolis, IN, USA
345 rdf:type schema:Organization
346 https://www.grid.ac/institutes/grid.412590.b schema:alternateName Michigan Medicine
347 schema:name Department of Surgery, University of Michigan Hospital, Ann Arbor, MI, USA
348 rdf:type schema:Organization
349 https://www.grid.ac/institutes/grid.413103.4 schema:alternateName Henry Ford Hospital
350 schema:name Department of Surgery, Henry Ford Hospital, Detroit, MI, USA
351 rdf:type schema:Organization
352 https://www.grid.ac/institutes/grid.413625.7 schema:alternateName Lehigh Valley Hospital
353 schema:name Department of Surgery, Lehigh Valley Hospital, Allentown, PA, USA
354 rdf:type schema:Organization
355 https://www.grid.ac/institutes/grid.413734.6 schema:alternateName NewYork–Presbyterian Hospital
356 schema:name Department of Surgery, Iris Cantor Women’s Health Center, The New York Presbyterian Hospital, Joan and Sanford Weill Medical College of Cornell University, New York, NY, USA
357 rdf:type schema:Organization
358 https://www.grid.ac/institutes/grid.414600.7 schema:alternateName Bridgeport Hospital
359 schema:name Department of Surgery, Bridgeport Hospital, Bridgeport, CT, USA
360 rdf:type schema:Organization
361 https://www.grid.ac/institutes/grid.415497.a schema:alternateName Genesys Regional Medical Center
362 schema:name Department of Surgery, Genesys Regional Medical Center, Grand Blanc, MI, USA
363 rdf:type schema:Organization
364 https://www.grid.ac/institutes/grid.415792.c schema:alternateName Lankenau Medical Center
365 schema:name Department of Surgery, Lankenau Medical Center, Wynnewood, PA, USA
366 rdf:type schema:Organization
367 https://www.grid.ac/institutes/grid.42505.36 schema:alternateName University of Southern California
368 schema:name Department of Surgery, University of Southern California, Los Angeles, CA, USA
369 rdf:type schema:Organization
370 https://www.grid.ac/institutes/grid.490448.5 schema:alternateName Providence Saint Joseph Medical Center
371 schema:name Department of Surgery, Providence Saint Joseph Medical Center, Burbank, CA, USA
372 rdf:type schema:Organization
373 https://www.grid.ac/institutes/grid.5386.8 schema:alternateName Cornell University
374 schema:name Department of Pathology, Weill Cornell Medical College, New York, NY, USA
375 rdf:type schema:Organization
376 https://www.grid.ac/institutes/grid.66875.3a schema:alternateName Mayo Clinic
377 schema:name Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN, USA
378 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...