Anastomotic Leakage Is Associated with Impaired Overall and Disease-Free Survival after Curative Rectal Cancer Resection: A Propensity Score Analysis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-10-28

AUTHORS

Yakup Kulu, Ignazio Tarantio, Rene Warschkow, Sandra Kny, Martin Schneider, Bruno M. Schmied, Markus W. Büchler, Alexis Ulrich

ABSTRACT

Background Whether anastomotic leakage (AL) has a negative impact on survival remains a matter of debate. This study aimed to assess the impact of AL on the overall and disease-free survival of patients undergoing curative resection of stages 1–3 rectal cancer using propensity-scoring methods.MethodsIn a single-center study, 570 patients undergoing curative resection of stages 1–3 rectal cancer between January 2002 and December 2011 were assessed. The mean follow-up period was 4.7 ± 2.9 years. Patients who did and did not experience AL were compared using Cox regression and propensity score analyses.ResultsOverall, 51 patients (8.9 %) experienced an AL. The characteristics of the patients were highly biased concerning AL (propensity score, 0.16 ± 0.12 vs. 0.09 ± 0.07; P < 0.001). Anastomotic leakage was uniformly associated with a significantly increased risk of mortality in unadjusted analysis [hazard ratio (HR) 2.30; 95 % confidence interval (CI) 1.40–3.76; P = 0.003], multivariable Cox regression (HR 2.27; 95 % CI 1.33–3.88; P = 0.005), and propensity score-adjusted Cox regression (HR 2.07; 95 % CI 1.21–3.55; P = 0.014). Similarly, disease-free survival was significantly impaired in patients who experienced AL according to unadjusted analysis (HR 1.88; 95 % CI 1.19–2.95; P = 0.011), multivariable Cox regression (HR 1.90; 95 % CI 1.17–3.09; P = 0.014), and propensity score-adjusted Cox regression (HR 2.31; 95 % CI 1.40–3.80; P = 0.002).ConclusionsThis is the first propensity score-based analysis providing evidence that oncologic outcome may be impaired after curative rectal cancer resection in patients with AL. More... »

PAGES

2059-2067

Identifiers

URI

http://scigraph.springernature.com/pub.10.1245/s10434-014-4187-3

DOI

http://dx.doi.org/10.1245/s10434-014-4187-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022366699

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25348782


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenocarcinoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anastomosis, Surgical", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anastomotic Leak", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Digestive System Surgical Procedures", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Recurrence, Local", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Staging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Propensity Score", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rectal Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany", 
          "id": "http://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kulu", 
        "givenName": "Yakup", 
        "id": "sg:person.0671704056.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671704056.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany", 
          "id": "http://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tarantio", 
        "givenName": "Ignazio", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Kantonsspital St. Gallen, St. Gallen, Switzerland", 
          "id": "http://www.grid.ac/institutes/grid.413349.8", 
          "name": [
            "Department of Surgery, Kantonsspital St. Gallen, St. Gallen, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Warschkow", 
        "givenName": "Rene", 
        "id": "sg:person.01000675257.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000675257.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany", 
          "id": "http://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kny", 
        "givenName": "Sandra", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany", 
          "id": "http://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schneider", 
        "givenName": "Martin", 
        "id": "sg:person.01176531455.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176531455.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Kantonsspital St. Gallen, St. Gallen, Switzerland", 
          "id": "http://www.grid.ac/institutes/grid.413349.8", 
          "name": [
            "Department of Surgery, Kantonsspital St. Gallen, St. Gallen, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schmied", 
        "givenName": "Bruno M.", 
        "id": "sg:person.01004372574.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004372574.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany", 
          "id": "http://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "B\u00fcchler", 
        "givenName": "Markus W.", 
        "id": "sg:person.07610347412.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07610347412.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany", 
          "id": "http://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ulrich", 
        "givenName": "Alexis", 
        "id": "sg:person.01017021755.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017021755.83"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/nature07205", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024729982", 
          "https://doi.org/10.1038/nature07205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-013-3173-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026292183", 
          "https://doi.org/10.1245/s10434-013-3173-5"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-10-28", 
    "datePublishedReg": "2014-10-28", 
    "description": "Background\nWhether anastomotic leakage (AL) has a negative impact on survival remains a matter of debate. This study aimed to assess the impact of AL on the overall and disease-free survival of patients undergoing curative resection of stages 1\u20133 rectal cancer using propensity-scoring methods.MethodsIn a single-center study, 570 patients undergoing curative resection of stages 1\u20133 rectal cancer between January 2002 and December 2011 were assessed. The mean follow-up period was 4.7\u00a0\u00b1\u00a02.9\u00a0years. Patients who did and did not experience AL were compared using Cox regression and propensity score analyses.ResultsOverall, 51 patients (8.9\u00a0%) experienced an AL. The characteristics of the patients were highly biased concerning AL (propensity score, 0.16\u00a0\u00b1\u00a00.12 vs. 0.09\u00a0\u00b1\u00a00.07; P\u00a0<\u00a00.001). Anastomotic leakage was uniformly associated with a significantly increased risk of mortality in unadjusted analysis [hazard ratio (HR) 2.30; 95\u00a0% confidence interval (CI) 1.40\u20133.76; P\u00a0=\u00a00.003], multivariable Cox regression (HR 2.27; 95\u00a0% CI 1.33\u20133.88; P\u00a0=\u00a00.005), and propensity score-adjusted Cox regression (HR 2.07; 95\u00a0% CI 1.21\u20133.55; P\u00a0=\u00a00.014). Similarly, disease-free survival was significantly impaired in patients who experienced AL according to unadjusted analysis (HR 1.88; 95\u00a0% CI 1.19\u20132.95; P\u00a0=\u00a00.011), multivariable Cox regression (HR 1.90; 95\u00a0% CI 1.17\u20133.09; P\u00a0=\u00a00.014), and propensity score-adjusted Cox regression (HR 2.31; 95\u00a0% CI 1.40\u20133.80; P\u00a0=\u00a00.002).ConclusionsThis is the first propensity score-based analysis providing evidence that oncologic outcome may be impaired after curative rectal cancer resection in patients with AL.", 
    "genre": "article", 
    "id": "sg:pub.10.1245/s10434-014-4187-3", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1105545", 
        "issn": [
          "1068-9265", 
          "1534-4681"
        ], 
        "name": "Annals of Surgical Oncology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "22"
      }
    ], 
    "keywords": [
      "disease-free survival", 
      "propensity score-adjusted Cox regression", 
      "curative rectal cancer resection", 
      "multivariable Cox regression", 
      "rectal cancer resection", 
      "anastomotic leakage", 
      "Cox regression", 
      "propensity score analysis", 
      "curative resection", 
      "rectal cancer", 
      "cancer resection", 
      "unadjusted analyses", 
      "impact of AL", 
      "propensity score-based analysis", 
      "score analysis", 
      "single-center study", 
      "risk of mortality", 
      "score-based analysis", 
      "stage 1", 
      "mean follow", 
      "oncologic outcomes", 
      "propensity score methods", 
      "patients", 
      "resection", 
      "matter of debate", 
      "survival", 
      "cancer", 
      "regression", 
      "ResultsOverall", 
      "follow", 
      "mortality", 
      "MethodsIn", 
      "ConclusionsThis", 
      "Overall", 
      "outcomes", 
      "risk", 
      "study", 
      "leakage", 
      "years", 
      "evidence", 
      "negative impact", 
      "analysis", 
      "period", 
      "background", 
      "impact", 
      "characteristics", 
      "method", 
      "matter", 
      "debate"
    ], 
    "name": "Anastomotic Leakage Is Associated with Impaired Overall and Disease-Free Survival after Curative Rectal Cancer Resection: A Propensity Score Analysis", 
    "pagination": "2059-2067", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1022366699"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1245/s10434-014-4187-3"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25348782"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1245/s10434-014-4187-3", 
      "https://app.dimensions.ai/details/publication/pub.1022366699"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-11-24T20:58", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_631.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1245/s10434-014-4187-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1245/s10434-014-4187-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1245/s10434-014-4187-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1245/s10434-014-4187-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1245/s10434-014-4187-3'


 

This table displays all metadata directly associated to this object as RDF triples.

236 TRIPLES      21 PREDICATES      93 URIs      83 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1245/s10434-014-4187-3 schema:about N09c5ced605aa48a1b19f8221e3413c96
2 N26ae2426742f47f68737b709822ecb75
3 N3a3cccb58f684b91a83d56daca1df6ee
4 N4b961865b8824ba79f3d745f23119bc9
5 N6344e55cba3146f2ada7e2fb6fde4368
6 N6ec1738a2673427893c64dc105794797
7 N738893cabf004f7d8dd081eab7a58e0a
8 N743ccf5ed1b94f09b4a83ddd0a12a88d
9 N776cac8ad9234723bd95421edc9e3fd6
10 N83169f7bb7ef453c91f0999aac46bc82
11 N93549306d3da48cbadd06d4e6ceaad85
12 Na1bdafaad856449c96bf31ed7acf4f70
13 Nb965c3cba31340e7900897ab8abe3afa
14 Nc20ebfa54d30477ab2dfaf20660e9b7b
15 Nc8c31487bd38409fb3b72bfb469c5ba2
16 Nce70f1ac3f0b42d4aacfc5e6f4028a8c
17 Nfbcb30c81bbd4f12926b998d4b03fb64
18 anzsrc-for:11
19 anzsrc-for:1112
20 schema:author N02763e8c873c4610847f6a3245d4aeda
21 schema:citation sg:pub.10.1038/nature07205
22 sg:pub.10.1245/s10434-013-3173-5
23 schema:datePublished 2014-10-28
24 schema:datePublishedReg 2014-10-28
25 schema:description Background Whether anastomotic leakage (AL) has a negative impact on survival remains a matter of debate. This study aimed to assess the impact of AL on the overall and disease-free survival of patients undergoing curative resection of stages 1–3 rectal cancer using propensity-scoring methods.MethodsIn a single-center study, 570 patients undergoing curative resection of stages 1–3 rectal cancer between January 2002 and December 2011 were assessed. The mean follow-up period was 4.7 ± 2.9 years. Patients who did and did not experience AL were compared using Cox regression and propensity score analyses.ResultsOverall, 51 patients (8.9 %) experienced an AL. The characteristics of the patients were highly biased concerning AL (propensity score, 0.16 ± 0.12 vs. 0.09 ± 0.07; P < 0.001). Anastomotic leakage was uniformly associated with a significantly increased risk of mortality in unadjusted analysis [hazard ratio (HR) 2.30; 95 % confidence interval (CI) 1.40–3.76; P = 0.003], multivariable Cox regression (HR 2.27; 95 % CI 1.33–3.88; P = 0.005), and propensity score-adjusted Cox regression (HR 2.07; 95 % CI 1.21–3.55; P = 0.014). Similarly, disease-free survival was significantly impaired in patients who experienced AL according to unadjusted analysis (HR 1.88; 95 % CI 1.19–2.95; P = 0.011), multivariable Cox regression (HR 1.90; 95 % CI 1.17–3.09; P = 0.014), and propensity score-adjusted Cox regression (HR 2.31; 95 % CI 1.40–3.80; P = 0.002).ConclusionsThis is the first propensity score-based analysis providing evidence that oncologic outcome may be impaired after curative rectal cancer resection in patients with AL.
26 schema:genre article
27 schema:isAccessibleForFree false
28 schema:isPartOf N165fd40159934ec58f445f8b9bfdaf8a
29 N3b8b9b196d60437dbb2ede304e106bc5
30 sg:journal.1105545
31 schema:keywords ConclusionsThis
32 Cox regression
33 MethodsIn
34 Overall
35 ResultsOverall
36 analysis
37 anastomotic leakage
38 background
39 cancer
40 cancer resection
41 characteristics
42 curative rectal cancer resection
43 curative resection
44 debate
45 disease-free survival
46 evidence
47 follow
48 impact
49 impact of AL
50 leakage
51 matter
52 matter of debate
53 mean follow
54 method
55 mortality
56 multivariable Cox regression
57 negative impact
58 oncologic outcomes
59 outcomes
60 patients
61 period
62 propensity score analysis
63 propensity score methods
64 propensity score-adjusted Cox regression
65 propensity score-based analysis
66 rectal cancer
67 rectal cancer resection
68 regression
69 resection
70 risk
71 risk of mortality
72 score analysis
73 score-based analysis
74 single-center study
75 stage 1
76 study
77 survival
78 unadjusted analyses
79 years
80 schema:name Anastomotic Leakage Is Associated with Impaired Overall and Disease-Free Survival after Curative Rectal Cancer Resection: A Propensity Score Analysis
81 schema:pagination 2059-2067
82 schema:productId N0f785e44cfc943c4aae6808bc1bb7a63
83 N2d04c6cf05cc4a3d98f8edcd1c8af850
84 N4566d8a40f724e6794f6dd9f8962f877
85 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022366699
86 https://doi.org/10.1245/s10434-014-4187-3
87 schema:sdDatePublished 2022-11-24T20:58
88 schema:sdLicense https://scigraph.springernature.com/explorer/license/
89 schema:sdPublisher Nca157d25486749a7b01da8eb38e9c61e
90 schema:url https://doi.org/10.1245/s10434-014-4187-3
91 sgo:license sg:explorer/license/
92 sgo:sdDataset articles
93 rdf:type schema:ScholarlyArticle
94 N02763e8c873c4610847f6a3245d4aeda rdf:first sg:person.0671704056.45
95 rdf:rest N6ba4925a1b41467f8e6696f5b0175ecc
96 N09c5ced605aa48a1b19f8221e3413c96 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Male
98 rdf:type schema:DefinedTerm
99 N0f785e44cfc943c4aae6808bc1bb7a63 schema:name dimensions_id
100 schema:value pub.1022366699
101 rdf:type schema:PropertyValue
102 N165fd40159934ec58f445f8b9bfdaf8a schema:issueNumber 6
103 rdf:type schema:PublicationIssue
104 N26ae2426742f47f68737b709822ecb75 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Neoplasm Recurrence, Local
106 rdf:type schema:DefinedTerm
107 N2d04c6cf05cc4a3d98f8edcd1c8af850 schema:name pubmed_id
108 schema:value 25348782
109 rdf:type schema:PropertyValue
110 N3a3cccb58f684b91a83d56daca1df6ee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Propensity Score
112 rdf:type schema:DefinedTerm
113 N3b8b9b196d60437dbb2ede304e106bc5 schema:volumeNumber 22
114 rdf:type schema:PublicationVolume
115 N3ee15d1c4b9f45b393c956b22dd37d74 schema:affiliation grid-institutes:grid.7700.0
116 schema:familyName Tarantio
117 schema:givenName Ignazio
118 rdf:type schema:Person
119 N4566d8a40f724e6794f6dd9f8962f877 schema:name doi
120 schema:value 10.1245/s10434-014-4187-3
121 rdf:type schema:PropertyValue
122 N4b961865b8824ba79f3d745f23119bc9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Female
124 rdf:type schema:DefinedTerm
125 N597f10f188cc485dbcb0954c416f3de2 rdf:first sg:person.01004372574.29
126 rdf:rest N710fefbb83da4711a642de8adf3c5edd
127 N6344e55cba3146f2ada7e2fb6fde4368 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Aged
129 rdf:type schema:DefinedTerm
130 N6ba4925a1b41467f8e6696f5b0175ecc rdf:first N3ee15d1c4b9f45b393c956b22dd37d74
131 rdf:rest N9be40aa3e8994b29bdb6d84b24948a8c
132 N6ec1738a2673427893c64dc105794797 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Prognosis
134 rdf:type schema:DefinedTerm
135 N710fefbb83da4711a642de8adf3c5edd rdf:first sg:person.07610347412.52
136 rdf:rest Nae79ae7fdd1942f8a222ae9693f62e47
137 N738893cabf004f7d8dd081eab7a58e0a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Survival Rate
139 rdf:type schema:DefinedTerm
140 N743ccf5ed1b94f09b4a83ddd0a12a88d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Middle Aged
142 rdf:type schema:DefinedTerm
143 N776cac8ad9234723bd95421edc9e3fd6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Humans
145 rdf:type schema:DefinedTerm
146 N83169f7bb7ef453c91f0999aac46bc82 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Retrospective Studies
148 rdf:type schema:DefinedTerm
149 N86088402b2cb4517ae29eeaa21cc05a1 rdf:first sg:person.01176531455.34
150 rdf:rest N597f10f188cc485dbcb0954c416f3de2
151 N93549306d3da48cbadd06d4e6ceaad85 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Anastomotic Leak
153 rdf:type schema:DefinedTerm
154 N9be40aa3e8994b29bdb6d84b24948a8c rdf:first sg:person.01000675257.95
155 rdf:rest Na5f6211e543640afb40da5cf678a27a4
156 Na1bdafaad856449c96bf31ed7acf4f70 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Follow-Up Studies
158 rdf:type schema:DefinedTerm
159 Na5f6211e543640afb40da5cf678a27a4 rdf:first Nbc14c38a6eb947f58bf7bfb7b67c7bbc
160 rdf:rest N86088402b2cb4517ae29eeaa21cc05a1
161 Nae79ae7fdd1942f8a222ae9693f62e47 rdf:first sg:person.01017021755.83
162 rdf:rest rdf:nil
163 Nb965c3cba31340e7900897ab8abe3afa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Anastomosis, Surgical
165 rdf:type schema:DefinedTerm
166 Nbc14c38a6eb947f58bf7bfb7b67c7bbc schema:affiliation grid-institutes:grid.7700.0
167 schema:familyName Kny
168 schema:givenName Sandra
169 rdf:type schema:Person
170 Nc20ebfa54d30477ab2dfaf20660e9b7b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Adenocarcinoma
172 rdf:type schema:DefinedTerm
173 Nc8c31487bd38409fb3b72bfb469c5ba2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Neoplasm Staging
175 rdf:type schema:DefinedTerm
176 Nca157d25486749a7b01da8eb38e9c61e schema:name Springer Nature - SN SciGraph project
177 rdf:type schema:Organization
178 Nce70f1ac3f0b42d4aacfc5e6f4028a8c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Digestive System Surgical Procedures
180 rdf:type schema:DefinedTerm
181 Nfbcb30c81bbd4f12926b998d4b03fb64 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Rectal Neoplasms
183 rdf:type schema:DefinedTerm
184 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
185 schema:name Medical and Health Sciences
186 rdf:type schema:DefinedTerm
187 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
188 schema:name Oncology and Carcinogenesis
189 rdf:type schema:DefinedTerm
190 sg:journal.1105545 schema:issn 1068-9265
191 1534-4681
192 schema:name Annals of Surgical Oncology
193 schema:publisher Springer Nature
194 rdf:type schema:Periodical
195 sg:person.01000675257.95 schema:affiliation grid-institutes:grid.413349.8
196 schema:familyName Warschkow
197 schema:givenName Rene
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000675257.95
199 rdf:type schema:Person
200 sg:person.01004372574.29 schema:affiliation grid-institutes:grid.413349.8
201 schema:familyName Schmied
202 schema:givenName Bruno M.
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004372574.29
204 rdf:type schema:Person
205 sg:person.01017021755.83 schema:affiliation grid-institutes:grid.7700.0
206 schema:familyName Ulrich
207 schema:givenName Alexis
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017021755.83
209 rdf:type schema:Person
210 sg:person.01176531455.34 schema:affiliation grid-institutes:grid.7700.0
211 schema:familyName Schneider
212 schema:givenName Martin
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176531455.34
214 rdf:type schema:Person
215 sg:person.0671704056.45 schema:affiliation grid-institutes:grid.7700.0
216 schema:familyName Kulu
217 schema:givenName Yakup
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671704056.45
219 rdf:type schema:Person
220 sg:person.07610347412.52 schema:affiliation grid-institutes:grid.7700.0
221 schema:familyName Büchler
222 schema:givenName Markus W.
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07610347412.52
224 rdf:type schema:Person
225 sg:pub.10.1038/nature07205 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024729982
226 https://doi.org/10.1038/nature07205
227 rdf:type schema:CreativeWork
228 sg:pub.10.1245/s10434-013-3173-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026292183
229 https://doi.org/10.1245/s10434-013-3173-5
230 rdf:type schema:CreativeWork
231 grid-institutes:grid.413349.8 schema:alternateName Department of Surgery, Kantonsspital St. Gallen, St. Gallen, Switzerland
232 schema:name Department of Surgery, Kantonsspital St. Gallen, St. Gallen, Switzerland
233 rdf:type schema:Organization
234 grid-institutes:grid.7700.0 schema:alternateName Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany
235 schema:name Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany
236 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...