Ontology type: schema:ScholarlyArticle Open Access: True
2012-12
AUTHORSMichael Rink, Daniel Sjoberg, Evi Comploj, Vitaly Margulis, Evanguelos Xylinas, Richard K. Lee, Jens Hansen, Eugene K. Cha, Jay D. Raman, Mesut Remzi, Karim Bensalah, Giacomo Novara, Surena F. Matin, Felix K. Chun, Eiji Kikuchi, Wassim Kassouf, Juan I. Martinez-Salamanca, Yair Lotan, Christian Seitz, Armin Pycha, Richard Zigeuner, Pierre I. Karakiewicz, Douglas S. Scherr, Andrew J. Vickers, Shahrokh F. Shariat
ABSTRACTPURPOSE: To describe the natural history and identify predictors of cancer-specific survival in patients who experience disease recurrence after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC). METHODS: Of 2,494 UTUC patients treated with RNU without neoadjuvant chemotherapy, 597 patients experienced disease recurrence. A total of 148 patients (25 %) received adjuvant chemotherapy before disease recurrence. Multivariable Cox regression model addressed time to cancer-specific mortality after disease recurrence. RESULTS: The median time from RNU to disease recurrence was 12 months (interquartile range 5-22). A total of 491 (82 %) of 597 patients died from UTUC, and 8 patients (1.3 %) died from other causes. The median time from disease recurrence to death of UTUC was 10 months. Actuarial cancer-specific survival estimate at 12 months after disease recurrence was 35 %. On multivariable analysis that adjusted for the effects of standard clinicopathologic characteristics, higher tumor stages [hazard ratio (HR) pT3 vs. pT0-T1: 1.66, p = 0.001; HR pT4 vs. pT0-T1: 1.90, p = 0.002], absence of lymph node dissection (HR 1.28, p = 0.041), ureteral tumor location (HR 1.44, p < 0.0005) and a shorter interval from surgery to disease recurrence (p < 0.0005) were significantly associated with cancer-specific mortality. The adjusted 6-, 12- and 24-month postrecurrence cancer-specific mortality was 73, 60 and 57 %, respectively. CONCLUSIONS: Approximately 80 % of patients who experience disease recurrence after RNU die within 2 years after recurrence. Patients with non-organ-confined stage, absence of lymph node dissection, ureteral tumor location and/or shorter time to disease recurrence died of their tumor more quickly than their counterparts. These factors should be considered in patient counseling and risk stratification for salvage treatment decision making. More... »
PAGES4337-4344
http://scigraph.springernature.com/pub.10.1245/s10434-012-2499-8
DOIhttp://dx.doi.org/10.1245/s10434-012-2499-8
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1016032865
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/22805867
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Oncology and Carcinogenesis",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cohort Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Follow-Up Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lymph Node Excision",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neoplasm Recurrence, Local",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neoplasm Staging",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Nephrectomy",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Prognosis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Risk Factors",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Survival Rate",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Ureteral Neoplasms",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University Medical Center Hamburg-Eppendorf",
"id": "https://www.grid.ac/institutes/grid.13648.38",
"name": [
"Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA",
"University Medical Center Hamburg-Eppendorf, Hamburg, Germany"
],
"type": "Organization"
},
"familyName": "Rink",
"givenName": "Michael",
"id": "sg:person.0715216436.18",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0715216436.18"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Memorial Sloan Kettering Cancer Center",
"id": "https://www.grid.ac/institutes/grid.51462.34",
"name": [
"Memorial Sloan Kettering Cancer Center, New York, NY, USA"
],
"type": "Organization"
},
"familyName": "Sjoberg",
"givenName": "Daniel",
"id": "sg:person.0721231014.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721231014.35"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"General Hospital of Bolzano, Bolzano, Italy"
],
"type": "Organization"
},
"familyName": "Comploj",
"givenName": "Evi",
"id": "sg:person.0764432452.13",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764432452.13"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "The University of Texas Southwestern Medical Center",
"id": "https://www.grid.ac/institutes/grid.267313.2",
"name": [
"University of Texas Southwestern Medical Center, Dallas, TX, USA"
],
"type": "Organization"
},
"familyName": "Margulis",
"givenName": "Vitaly",
"id": "sg:person.0700013535.70",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700013535.70"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "NewYork\u2013Presbyterian Hospital",
"id": "https://www.grid.ac/institutes/grid.413734.6",
"name": [
"Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA",
"Cochin Hospital, APHP, Paris Descartes University, Paris, France"
],
"type": "Organization"
},
"familyName": "Xylinas",
"givenName": "Evanguelos",
"id": "sg:person.01233162246.75",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233162246.75"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "NewYork\u2013Presbyterian Hospital",
"id": "https://www.grid.ac/institutes/grid.413734.6",
"name": [
"Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA"
],
"type": "Organization"
},
"familyName": "Lee",
"givenName": "Richard K.",
"id": "sg:person.01000407764.23",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000407764.23"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Montreal",
"id": "https://www.grid.ac/institutes/grid.14848.31",
"name": [
"University Medical Center Hamburg-Eppendorf, Hamburg, Germany",
"University of Montr\u00e9al, Montreal, Quebec, Canada"
],
"type": "Organization"
},
"familyName": "Hansen",
"givenName": "Jens",
"id": "sg:person.01272011717.40",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272011717.40"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "NewYork\u2013Presbyterian Hospital",
"id": "https://www.grid.ac/institutes/grid.413734.6",
"name": [
"Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA"
],
"type": "Organization"
},
"familyName": "Cha",
"givenName": "Eugene K.",
"id": "sg:person.01103103027.63",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103103027.63"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Penn State Milton S. Hershey Medical Center",
"id": "https://www.grid.ac/institutes/grid.240473.6",
"name": [
"Penn State Milton S. Hershey Medical Center, Hershey, PA, USA"
],
"type": "Organization"
},
"familyName": "Raman",
"givenName": "Jay D.",
"id": "sg:person.01162751564.70",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162751564.70"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Hospital Weinviertel-Korneuburg, Korneuburg, Austria"
],
"type": "Organization"
},
"familyName": "Remzi",
"givenName": "Mesut",
"id": "sg:person.0720377332.10",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0720377332.10"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Rennes 1",
"id": "https://www.grid.ac/institutes/grid.410368.8",
"name": [
"University of Rennes, Rennes, France"
],
"type": "Organization"
},
"familyName": "Bensalah",
"givenName": "Karim",
"id": "sg:person.01070707443.14",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070707443.14"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Padua",
"id": "https://www.grid.ac/institutes/grid.5608.b",
"name": [
"University of Padua, Padua, Italy"
],
"type": "Organization"
},
"familyName": "Novara",
"givenName": "Giacomo",
"id": "sg:person.01114636364.97",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114636364.97"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "The University of Texas MD Anderson Cancer Center",
"id": "https://www.grid.ac/institutes/grid.240145.6",
"name": [
"MD Anderson Cancer Center, Houston, TX, USA"
],
"type": "Organization"
},
"familyName": "Matin",
"givenName": "Surena F.",
"id": "sg:person.0675713004.57",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675713004.57"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University Medical Center Hamburg-Eppendorf",
"id": "https://www.grid.ac/institutes/grid.13648.38",
"name": [
"University Medical Center Hamburg-Eppendorf, Hamburg, Germany"
],
"type": "Organization"
},
"familyName": "Chun",
"givenName": "Felix K.",
"id": "sg:person.07426704167.72",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07426704167.72"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Keio University",
"id": "https://www.grid.ac/institutes/grid.26091.3c",
"name": [
"Keio University School of Medicine, Tokyo, Japan"
],
"type": "Organization"
},
"familyName": "Kikuchi",
"givenName": "Eiji",
"id": "sg:person.01164152004.06",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01164152004.06"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "McGill University Health Centre",
"id": "https://www.grid.ac/institutes/grid.63984.30",
"name": [
"McGill University Health Center, Montreal, Quebec, Canada"
],
"type": "Organization"
},
"familyName": "Kassouf",
"givenName": "Wassim",
"id": "sg:person.01261265212.37",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261265212.37"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitario Puerta de Hierro Majadahonda",
"id": "https://www.grid.ac/institutes/grid.73221.35",
"name": [
"University Hospital Puerta de Hierro-Majadahonda, Madrid, Spain"
],
"type": "Organization"
},
"familyName": "Martinez-Salamanca",
"givenName": "Juan I.",
"id": "sg:person.01353061072.03",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353061072.03"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "The University of Texas Southwestern Medical Center",
"id": "https://www.grid.ac/institutes/grid.267313.2",
"name": [
"University of Texas Southwestern Medical Center, Dallas, TX, USA"
],
"type": "Organization"
},
"familyName": "Lotan",
"givenName": "Yair",
"id": "sg:person.01004736112.33",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004736112.33"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"St. John of God Hospital, Teaching Hospital of the Medical University, Vienna, Austria"
],
"type": "Organization"
},
"familyName": "Seitz",
"givenName": "Christian",
"id": "sg:person.0736135664.78",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736135664.78"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"General Hospital of Bolzano, Bolzano, Italy"
],
"type": "Organization"
},
"familyName": "Pycha",
"givenName": "Armin",
"id": "sg:person.0751464473.28",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751464473.28"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical University of Graz",
"id": "https://www.grid.ac/institutes/grid.11598.34",
"name": [
"Medical University of Graz, Graz, Austria"
],
"type": "Organization"
},
"familyName": "Zigeuner",
"givenName": "Richard",
"id": "sg:person.01224013051.78",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224013051.78"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Montreal",
"id": "https://www.grid.ac/institutes/grid.14848.31",
"name": [
"University of Montr\u00e9al, Montreal, Quebec, Canada"
],
"type": "Organization"
},
"familyName": "Karakiewicz",
"givenName": "Pierre I.",
"id": "sg:person.0717124312.21",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717124312.21"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "NewYork\u2013Presbyterian Hospital",
"id": "https://www.grid.ac/institutes/grid.413734.6",
"name": [
"Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA"
],
"type": "Organization"
},
"familyName": "Scherr",
"givenName": "Douglas S.",
"id": "sg:person.0670022464.49",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670022464.49"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Memorial Sloan Kettering Cancer Center",
"id": "https://www.grid.ac/institutes/grid.51462.34",
"name": [
"Memorial Sloan Kettering Cancer Center, New York, NY, USA"
],
"type": "Organization"
},
"familyName": "Vickers",
"givenName": "Andrew J.",
"id": "sg:person.01056543145.21",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056543145.21"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "NewYork\u2013Presbyterian Hospital",
"id": "https://www.grid.ac/institutes/grid.413734.6",
"name": [
"Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA"
],
"type": "Organization"
},
"familyName": "Shariat",
"givenName": "Shahrokh F.",
"id": "sg:person.01260166612.12",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260166612.12"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1002/cncr.22970",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001132919"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1464-410x.2008.08003.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004758395"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2011.07.009",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005066896"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2012.02.018",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008184303"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.urolonc.2010.02.011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011598462"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2012.02.030",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013474483"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2011.12.055",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019292350"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2012.01.021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019720299"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.juro.2009.05.011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019932232"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3322/caac.20138",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020626779"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/cncr.23162",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021526474"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/modpathol.3800529",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021794441",
"https://doi.org/10.1038/modpathol.3800529"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/modpathol.3800529",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021794441",
"https://doi.org/10.1038/modpathol.3800529"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2009.11.035",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022217110"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1464-410x.2006.06519.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022782773"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1464-410x.2009.08821.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025235231"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1464-410x.2009.08821.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025235231"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2010.12.042",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025705384"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2009.12.029",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026698907"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2008.17.2361",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027132206"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2011.09.017",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027609715"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1464-410x.2011.10792.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027934536"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/cncr.24135",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033669387"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.urology.2009.07.1296",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036395082"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1464-410x.1998.00800.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036756579"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1464-410x.2011.10455.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037059829"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2008.01.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037847512"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1155/2009/419028",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042242429"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1464-410x.2011.10075.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050585372"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10147-011-0234-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051678216",
"https://doi.org/10.1007/s10147-011-0234-2"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2011.05.049",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052024544"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2009.07.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052268548"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.eururo.2007.04.070",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052898237"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrurol.2011.96",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053453077",
"https://doi.org/10.1038/nrurol.2011.96"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.1999.17.10.3173",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074528556"
],
"type": "CreativeWork"
}
],
"datePublished": "2012-12",
"datePublishedReg": "2012-12-01",
"description": "PURPOSE: To describe the natural history and identify predictors of cancer-specific survival in patients who experience disease recurrence after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC).\nMETHODS: Of 2,494 UTUC patients treated with RNU without neoadjuvant chemotherapy, 597 patients experienced disease recurrence. A total of 148 patients (25 %) received adjuvant chemotherapy before disease recurrence. Multivariable Cox regression model addressed time to cancer-specific mortality after disease recurrence.\nRESULTS: The median time from RNU to disease recurrence was 12 months (interquartile range 5-22). A total of 491 (82 %) of 597 patients died from UTUC, and 8 patients (1.3 %) died from other causes. The median time from disease recurrence to death of UTUC was 10 months. Actuarial cancer-specific survival estimate at 12 months after disease recurrence was 35 %. On multivariable analysis that adjusted for the effects of standard clinicopathologic characteristics, higher tumor stages [hazard ratio (HR) pT3 vs. pT0-T1: 1.66, p = 0.001; HR pT4 vs. pT0-T1: 1.90, p = 0.002], absence of lymph node dissection (HR 1.28, p = 0.041), ureteral tumor location (HR 1.44, p < 0.0005) and a shorter interval from surgery to disease recurrence (p < 0.0005) were significantly associated with cancer-specific mortality. The adjusted 6-, 12- and 24-month postrecurrence cancer-specific mortality was 73, 60 and 57 %, respectively.\nCONCLUSIONS: Approximately 80 % of patients who experience disease recurrence after RNU die within 2 years after recurrence. Patients with non-organ-confined stage, absence of lymph node dissection, ureteral tumor location and/or shorter time to disease recurrence died of their tumor more quickly than their counterparts. These factors should be considered in patient counseling and risk stratification for salvage treatment decision making.",
"genre": "research_article",
"id": "sg:pub.10.1245/s10434-012-2499-8",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isFundedItemOf": [
{
"id": "sg:grant.2682753",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.2631835",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.2440174",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1105545",
"issn": [
"1068-9265",
"1534-4681"
],
"name": "Annals of Surgical Oncology",
"type": "Periodical"
},
{
"issueNumber": "13",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "19"
}
],
"name": "Risk of Cancer-specific Mortality following Recurrence After Radical Nephroureterectomy",
"pagination": "4337-4344",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"4c64bbf3d01476d7d599048ac644a2c701731bdf9c7dca10f513060547afc360"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"22805867"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9420840"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1245/s10434-012-2499-8"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1016032865"
]
}
],
"sameAs": [
"https://doi.org/10.1245/s10434-012-2499-8",
"https://app.dimensions.ai/details/publication/pub.1016032865"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T10:58",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000352_0000000352/records_60333_00000000.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1245/s10434-012-2499-8"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1245/s10434-012-2499-8'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1245/s10434-012-2499-8'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1245/s10434-012-2499-8'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1245/s10434-012-2499-8'
This table displays all metadata directly associated to this object as RDF triples.
452 TRIPLES
21 PREDICATES
77 URIs
36 LITERALS
24 BLANK NODES