Pancreatic Resection of Isolated Metastases from Nonpancreatic Primary Cancers View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-11

AUTHORS

Sushanth Reddy, Barish H. Edil, John L. Cameron, Timothy M. Pawlik, Joseph M. Herman, Marta M. Gilson, Kurtis A. Campbell, Richard D. Schulick, Nita Ahuja, Christopher L. Wolfgang

ABSTRACT

BACKGROUND: The goal of this study is to report the safety and efficacy of pancreatic resection for isolated metastatic cancers from nonpancreatic primary disease. METHODS: We retrospectively identified patients from a single institution's prospectively gathered pancreaticobiliary database from 1970 to 2007 who underwent a pancreatic resection for metastatic disease. RESULTS: Forty-nine patients were identified with metastatic lesions to the pancreas. Pancreaticoduodenectomy, distal pancreatectomy, and total pancreatectomy were performed in 31, 14, and 4 patients, respectively. Pathology distribution was as follows: 21 renal cell carcinoma (RCC), 6 gallbladder cancer, 4 lung cancer, 4 ovarian cancer, 4 sarcoma, 3 melanoma, 2 colon cancer, 1 breast cancer, 1 hepatocellular carcinoma, 1 seminoma, 1 Langerhans cell histiocytosis, and 1 nonpancreatic endocrine cancer. Postoperative morbidity was 48%. There were no perioperative deaths. A statistically significant difference in survival was found between cancer types (P = .007) with median survivals ranging from 4.8 years for RCC to .9 years for melanoma. Univariate analysis demonstrated a survival disadvantage for patients with perineural (hazard ratio [HR] = 5.4, P = .004) and vascular invasion (HR = 4.4, P = .002). The most commonly resected metastatic lesion of the pancreas was RCC. Eighteen of the 23 patients with RCC had a metachronous lesion with a median length between initial operation and pancreatic resection of 9.3 years. Metachronous lesions had a survival similar to that of synchronous lesions (HR = 1.0, P = .98). Vascular invasion (HR = 2.4, P = .007) and lymph node metastases (HR = 24.1, P = .01) were associated with greater mortality. CONCLUSION: Long-term survival can be achieved in patients undergoing resection of isolated metastases to the pancreas. More... »

PAGES

3199-3206

Identifiers

URI

http://scigraph.springernature.com/pub.10.1245/s10434-008-0140-7

DOI

http://dx.doi.org/10.1245/s10434-008-0140-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047654230

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18784960


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Comorbidity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pancreatectomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pancreatic Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, 21287, Baltimore, Maryland, USA", 
            "The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21287, Baltimore, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Reddy", 
        "givenName": "Sushanth", 
        "id": "sg:person.01361176752.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361176752.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, 21287, Baltimore, Maryland, USA", 
            "The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21287, Baltimore, Maryland, USA", 
            "Department of Oncology, The Johns Hopkins University, 21287, Baltimore, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Edil", 
        "givenName": "Barish H.", 
        "id": "sg:person.01116422516.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116422516.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, 21287, Baltimore, Maryland, USA", 
            "The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21287, Baltimore, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cameron", 
        "givenName": "John L.", 
        "id": "sg:person.011317137122.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011317137122.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, 21287, Baltimore, Maryland, USA", 
            "The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21287, Baltimore, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pawlik", 
        "givenName": "Timothy M.", 
        "id": "sg:person.0721627074.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721627074.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21287, Baltimore, Maryland, USA", 
            "Department of Oncology, The Johns Hopkins University, 21287, Baltimore, Maryland, USA", 
            "Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University, 21287, Baltimore, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Herman", 
        "givenName": "Joseph M.", 
        "id": "sg:person.015567603732.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015567603732.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, 21287, Baltimore, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gilson", 
        "givenName": "Marta M.", 
        "id": "sg:person.0750412500.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750412500.96"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, 21287, Baltimore, Maryland, USA", 
            "The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21287, Baltimore, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Campbell", 
        "givenName": "Kurtis A.", 
        "id": "sg:person.015103230222.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015103230222.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, 21287, Baltimore, Maryland, USA", 
            "The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21287, Baltimore, Maryland, USA", 
            "Department of Oncology, The Johns Hopkins University, 21287, Baltimore, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schulick", 
        "givenName": "Richard D.", 
        "id": "sg:person.013701724657.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013701724657.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, 21287, Baltimore, Maryland, USA", 
            "The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21287, Baltimore, Maryland, USA", 
            "Department of Oncology, The Johns Hopkins University, 21287, Baltimore, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ahuja", 
        "givenName": "Nita", 
        "id": "sg:person.01043401657.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043401657.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, 21287, Baltimore, Maryland, USA", 
            "The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21287, Baltimore, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wolfgang", 
        "givenName": "Christopher L.", 
        "id": "sg:person.013555514237.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013555514237.73"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf02574484", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010723011", 
          "https://doi.org/10.1007/bf02574484"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02574484", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010723011", 
          "https://doi.org/10.1007/bf02574484"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9610(78)90072-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010882949"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.1800800837", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015971048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1016/s1091-255x(01)80060-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016526318", 
          "https://doi.org/10.1016/s1091-255x(01)80060-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1440-1746.2007.05178.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019382229"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2004.06.132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022235480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0090-4295(00)00639-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022939699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4065/75.6.581", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022960284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000133083.54934.ae", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024049438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000133083.54934.ae", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024049438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000133083.54934.ae", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024049438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.141.6.537", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028598361"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.133.4.413", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028847017"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.73.2.163", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030920964"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1016/j.gassur.2006.08.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031265211", 
          "https://doi.org/10.1016/j.gassur.2006.08.018"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/aso.2003.02.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040268392", 
          "https://doi.org/10.1245/aso.2003.02.003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/aso.2003.02.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040268392", 
          "https://doi.org/10.1245/aso.2003.02.003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.84.4.442", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040966174"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jso.10262", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041191922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-005-0464-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042234224", 
          "https://doi.org/10.1007/s00268-005-0464-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-005-0464-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042234224", 
          "https://doi.org/10.1007/s00268-005-0464-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-007-9782-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043465975", 
          "https://doi.org/10.1245/s10434-007-9782-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00104-007-1390-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047983663", 
          "https://doi.org/10.1007/s00104-007-1390-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00104-007-1390-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047983663", 
          "https://doi.org/10.1007/s00104-007-1390-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(19881001)62:7<1397::aid-cncr2820620726>3.0.co;2-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050220448"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000134475", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051054166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074953939", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075760861", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076511279", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079458389", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079947413", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080109709", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081738592", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082485139", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-11", 
    "datePublishedReg": "2008-11-01", 
    "description": "BACKGROUND: The goal of this study is to report the safety and efficacy of pancreatic resection for isolated metastatic cancers from nonpancreatic primary disease.\nMETHODS: We retrospectively identified patients from a single institution's prospectively gathered pancreaticobiliary database from 1970 to 2007 who underwent a pancreatic resection for metastatic disease.\nRESULTS: Forty-nine patients were identified with metastatic lesions to the pancreas. Pancreaticoduodenectomy, distal pancreatectomy, and total pancreatectomy were performed in 31, 14, and 4 patients, respectively. Pathology distribution was as follows: 21 renal cell carcinoma (RCC), 6 gallbladder cancer, 4 lung cancer, 4 ovarian cancer, 4 sarcoma, 3 melanoma, 2 colon cancer, 1 breast cancer, 1 hepatocellular carcinoma, 1 seminoma, 1 Langerhans cell histiocytosis, and 1 nonpancreatic endocrine cancer. Postoperative morbidity was 48%. There were no perioperative deaths. A statistically significant difference in survival was found between cancer types (P = .007) with median survivals ranging from 4.8 years for RCC to .9 years for melanoma. Univariate analysis demonstrated a survival disadvantage for patients with perineural (hazard ratio [HR] = 5.4, P = .004) and vascular invasion (HR = 4.4, P = .002). The most commonly resected metastatic lesion of the pancreas was RCC. Eighteen of the 23 patients with RCC had a metachronous lesion with a median length between initial operation and pancreatic resection of 9.3 years. Metachronous lesions had a survival similar to that of synchronous lesions (HR = 1.0, P = .98). Vascular invasion (HR = 2.4, P = .007) and lymph node metastases (HR = 24.1, P = .01) were associated with greater mortality.\nCONCLUSION: Long-term survival can be achieved in patients undergoing resection of isolated metastases to the pancreas.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1245/s10434-008-0140-7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1105545", 
        "issn": [
          "1068-9265", 
          "1534-4681"
        ], 
        "name": "Annals of Surgical Oncology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "11", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "15"
      }
    ], 
    "name": "Pancreatic Resection of Isolated Metastases from Nonpancreatic Primary Cancers", 
    "pagination": "3199-3206", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "e303147bb75ae0dea66f048452a780492e1d1c2c37ec40ce67d7bf02b7d13ee7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18784960"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9420840"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1245/s10434-008-0140-7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1047654230"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1245/s10434-008-0140-7", 
      "https://app.dimensions.ai/details/publication/pub.1047654230"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T22:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8690_00000501.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1245/s10434-008-0140-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1245/s10434-008-0140-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1245/s10434-008-0140-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1245/s10434-008-0140-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1245/s10434-008-0140-7'


 

This table displays all metadata directly associated to this object as RDF triples.

277 TRIPLES      21 PREDICATES      72 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1245/s10434-008-0140-7 schema:about N135a304fda7e4f5cbff9c9bfd8eec745
2 N30bb82ad2cfa467797a71a23e1206c27
3 N48dc034ce3914e6699ae058f7c633ed9
4 N4e7dfe78e0a14be6831ae8c23d6b3c0f
5 N5d83a06a84994cc88d9dba386ce5100e
6 N6698b89e446746cebf2a85c951b491cd
7 N7ce6d63e6eb24d1d95fddcf16a654b56
8 N89c2b630bf7a4942964add679df33e38
9 N9faaaf4eb40242b7a2a0433a41f115fe
10 Na4b8694b656c4540884ca656b05c8fbf
11 Nae52864866b34b4580401ccd11be9165
12 Nc2d1e0352f3644ceacc08657c4411f24
13 Nc61f5054f5f043d5acd65ff7f1e7bc5b
14 Nd5d5ea2b941041c98a08fc3627184366
15 anzsrc-for:11
16 anzsrc-for:1112
17 schema:author Nc39da7f40d3f4ba1b50efe180b33bb4e
18 schema:citation sg:pub.10.1007/bf02574484
19 sg:pub.10.1007/s00104-007-1390-9
20 sg:pub.10.1007/s00268-005-0464-4
21 sg:pub.10.1016/j.gassur.2006.08.018
22 sg:pub.10.1016/s1091-255x(01)80060-3
23 sg:pub.10.1245/aso.2003.02.003
24 sg:pub.10.1245/s10434-007-9782-0
25 https://app.dimensions.ai/details/publication/pub.1074953939
26 https://app.dimensions.ai/details/publication/pub.1075760861
27 https://app.dimensions.ai/details/publication/pub.1076511279
28 https://app.dimensions.ai/details/publication/pub.1079458389
29 https://app.dimensions.ai/details/publication/pub.1079947413
30 https://app.dimensions.ai/details/publication/pub.1080109709
31 https://app.dimensions.ai/details/publication/pub.1081738592
32 https://app.dimensions.ai/details/publication/pub.1082485139
33 https://doi.org/10.1001/archsurg.133.4.413
34 https://doi.org/10.1001/archsurg.141.6.537
35 https://doi.org/10.1002/1097-0142(19881001)62:7<1397::aid-cncr2820620726>3.0.co;2-2
36 https://doi.org/10.1002/bjs.1800800837
37 https://doi.org/10.1002/jso.10262
38 https://doi.org/10.1016/0002-9610(78)90072-7
39 https://doi.org/10.1016/s0090-4295(00)00639-7
40 https://doi.org/10.1097/01.sla.0000133083.54934.ae
41 https://doi.org/10.1111/j.1440-1746.2007.05178.x
42 https://doi.org/10.1159/000134475
43 https://doi.org/10.1200/jco.2004.06.132
44 https://doi.org/10.1378/chest.73.2.163
45 https://doi.org/10.1378/chest.84.4.442
46 https://doi.org/10.4065/75.6.581
47 schema:datePublished 2008-11
48 schema:datePublishedReg 2008-11-01
49 schema:description BACKGROUND: The goal of this study is to report the safety and efficacy of pancreatic resection for isolated metastatic cancers from nonpancreatic primary disease. METHODS: We retrospectively identified patients from a single institution's prospectively gathered pancreaticobiliary database from 1970 to 2007 who underwent a pancreatic resection for metastatic disease. RESULTS: Forty-nine patients were identified with metastatic lesions to the pancreas. Pancreaticoduodenectomy, distal pancreatectomy, and total pancreatectomy were performed in 31, 14, and 4 patients, respectively. Pathology distribution was as follows: 21 renal cell carcinoma (RCC), 6 gallbladder cancer, 4 lung cancer, 4 ovarian cancer, 4 sarcoma, 3 melanoma, 2 colon cancer, 1 breast cancer, 1 hepatocellular carcinoma, 1 seminoma, 1 Langerhans cell histiocytosis, and 1 nonpancreatic endocrine cancer. Postoperative morbidity was 48%. There were no perioperative deaths. A statistically significant difference in survival was found between cancer types (P = .007) with median survivals ranging from 4.8 years for RCC to .9 years for melanoma. Univariate analysis demonstrated a survival disadvantage for patients with perineural (hazard ratio [HR] = 5.4, P = .004) and vascular invasion (HR = 4.4, P = .002). The most commonly resected metastatic lesion of the pancreas was RCC. Eighteen of the 23 patients with RCC had a metachronous lesion with a median length between initial operation and pancreatic resection of 9.3 years. Metachronous lesions had a survival similar to that of synchronous lesions (HR = 1.0, P = .98). Vascular invasion (HR = 2.4, P = .007) and lymph node metastases (HR = 24.1, P = .01) were associated with greater mortality. CONCLUSION: Long-term survival can be achieved in patients undergoing resection of isolated metastases to the pancreas.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree false
53 schema:isPartOf N9aa0f0219d0f4b97907186c44ade0b14
54 Nf884a794e68941a3a4b7985ce3aeb128
55 sg:journal.1105545
56 schema:name Pancreatic Resection of Isolated Metastases from Nonpancreatic Primary Cancers
57 schema:pagination 3199-3206
58 schema:productId N3d728da7cd07414b98a76cfcbcc88fd2
59 N5988c1dfb1e24c89961d674d8074951e
60 Na05454c5460241d883df0f476cd7ebd9
61 Nb6ffc1468580408faad22393d346ff98
62 Nf5356c953dac4a76954aebd793686252
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047654230
64 https://doi.org/10.1245/s10434-008-0140-7
65 schema:sdDatePublished 2019-04-10T22:29
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher N8f8f8030adda478c845121b693d469a2
68 schema:url http://link.springer.com/10.1245/s10434-008-0140-7
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N135a304fda7e4f5cbff9c9bfd8eec745 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Prospective Studies
74 rdf:type schema:DefinedTerm
75 N18950a3fc424423486d5bc15c403cea0 rdf:first sg:person.013701724657.77
76 rdf:rest N9d3095601688421ba588ed32935d6f46
77 N23a0636466544e7e86c0ca22c1e6635f rdf:first sg:person.015567603732.54
78 rdf:rest N2a30439c9f3b44d98781a162bde704d5
79 N2a30439c9f3b44d98781a162bde704d5 rdf:first sg:person.0750412500.96
80 rdf:rest Na297d5588f2444999370582399579967
81 N30bb82ad2cfa467797a71a23e1206c27 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Pancreatic Neoplasms
83 rdf:type schema:DefinedTerm
84 N3d728da7cd07414b98a76cfcbcc88fd2 schema:name dimensions_id
85 schema:value pub.1047654230
86 rdf:type schema:PropertyValue
87 N48dc034ce3914e6699ae058f7c633ed9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Female
89 rdf:type schema:DefinedTerm
90 N4e7dfe78e0a14be6831ae8c23d6b3c0f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Prognosis
92 rdf:type schema:DefinedTerm
93 N4f656f850d2047339df7b295571d5b7a rdf:first sg:person.01116422516.18
94 rdf:rest Nda8c3bd78c3c4b6f8248e16da1d4b8af
95 N5988c1dfb1e24c89961d674d8074951e schema:name pubmed_id
96 schema:value 18784960
97 rdf:type schema:PropertyValue
98 N5d83a06a84994cc88d9dba386ce5100e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Neoplasms
100 rdf:type schema:DefinedTerm
101 N6698b89e446746cebf2a85c951b491cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Survival Rate
103 rdf:type schema:DefinedTerm
104 N7ce6d63e6eb24d1d95fddcf16a654b56 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Pancreatectomy
106 rdf:type schema:DefinedTerm
107 N89c2b630bf7a4942964add679df33e38 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Treatment Outcome
109 rdf:type schema:DefinedTerm
110 N8f8f8030adda478c845121b693d469a2 schema:name Springer Nature - SN SciGraph project
111 rdf:type schema:Organization
112 N9aa0f0219d0f4b97907186c44ade0b14 schema:volumeNumber 15
113 rdf:type schema:PublicationVolume
114 N9c0c7bb419ef47d2a118f2a70fd33d14 rdf:first sg:person.013555514237.73
115 rdf:rest rdf:nil
116 N9d3095601688421ba588ed32935d6f46 rdf:first sg:person.01043401657.70
117 rdf:rest N9c0c7bb419ef47d2a118f2a70fd33d14
118 N9faaaf4eb40242b7a2a0433a41f115fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Retrospective Studies
120 rdf:type schema:DefinedTerm
121 Na05454c5460241d883df0f476cd7ebd9 schema:name doi
122 schema:value 10.1245/s10434-008-0140-7
123 rdf:type schema:PropertyValue
124 Na297d5588f2444999370582399579967 rdf:first sg:person.015103230222.72
125 rdf:rest N18950a3fc424423486d5bc15c403cea0
126 Na4b8694b656c4540884ca656b05c8fbf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Humans
128 rdf:type schema:DefinedTerm
129 Nae52864866b34b4580401ccd11be9165 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Comorbidity
131 rdf:type schema:DefinedTerm
132 Nb6ffc1468580408faad22393d346ff98 schema:name readcube_id
133 schema:value e303147bb75ae0dea66f048452a780492e1d1c2c37ec40ce67d7bf02b7d13ee7
134 rdf:type schema:PropertyValue
135 Nc2d1e0352f3644ceacc08657c4411f24 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Aged
137 rdf:type schema:DefinedTerm
138 Nc39da7f40d3f4ba1b50efe180b33bb4e rdf:first sg:person.01361176752.36
139 rdf:rest N4f656f850d2047339df7b295571d5b7a
140 Nc61f5054f5f043d5acd65ff7f1e7bc5b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Male
142 rdf:type schema:DefinedTerm
143 Ncffacd2e86e447b48bd3dd8e50c01640 rdf:first sg:person.0721627074.41
144 rdf:rest N23a0636466544e7e86c0ca22c1e6635f
145 Nd5d5ea2b941041c98a08fc3627184366 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Middle Aged
147 rdf:type schema:DefinedTerm
148 Nda8c3bd78c3c4b6f8248e16da1d4b8af rdf:first sg:person.011317137122.71
149 rdf:rest Ncffacd2e86e447b48bd3dd8e50c01640
150 Nf5356c953dac4a76954aebd793686252 schema:name nlm_unique_id
151 schema:value 9420840
152 rdf:type schema:PropertyValue
153 Nf884a794e68941a3a4b7985ce3aeb128 schema:issueNumber 11
154 rdf:type schema:PublicationIssue
155 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
156 schema:name Medical and Health Sciences
157 rdf:type schema:DefinedTerm
158 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
159 schema:name Oncology and Carcinogenesis
160 rdf:type schema:DefinedTerm
161 sg:journal.1105545 schema:issn 1068-9265
162 1534-4681
163 schema:name Annals of Surgical Oncology
164 rdf:type schema:Periodical
165 sg:person.01043401657.70 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
166 schema:familyName Ahuja
167 schema:givenName Nita
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043401657.70
169 rdf:type schema:Person
170 sg:person.01116422516.18 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
171 schema:familyName Edil
172 schema:givenName Barish H.
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116422516.18
174 rdf:type schema:Person
175 sg:person.011317137122.71 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
176 schema:familyName Cameron
177 schema:givenName John L.
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011317137122.71
179 rdf:type schema:Person
180 sg:person.013555514237.73 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
181 schema:familyName Wolfgang
182 schema:givenName Christopher L.
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013555514237.73
184 rdf:type schema:Person
185 sg:person.01361176752.36 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
186 schema:familyName Reddy
187 schema:givenName Sushanth
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361176752.36
189 rdf:type schema:Person
190 sg:person.013701724657.77 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
191 schema:familyName Schulick
192 schema:givenName Richard D.
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013701724657.77
194 rdf:type schema:Person
195 sg:person.015103230222.72 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
196 schema:familyName Campbell
197 schema:givenName Kurtis A.
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015103230222.72
199 rdf:type schema:Person
200 sg:person.015567603732.54 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
201 schema:familyName Herman
202 schema:givenName Joseph M.
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015567603732.54
204 rdf:type schema:Person
205 sg:person.0721627074.41 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
206 schema:familyName Pawlik
207 schema:givenName Timothy M.
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721627074.41
209 rdf:type schema:Person
210 sg:person.0750412500.96 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
211 schema:familyName Gilson
212 schema:givenName Marta M.
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750412500.96
214 rdf:type schema:Person
215 sg:pub.10.1007/bf02574484 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010723011
216 https://doi.org/10.1007/bf02574484
217 rdf:type schema:CreativeWork
218 sg:pub.10.1007/s00104-007-1390-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047983663
219 https://doi.org/10.1007/s00104-007-1390-9
220 rdf:type schema:CreativeWork
221 sg:pub.10.1007/s00268-005-0464-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042234224
222 https://doi.org/10.1007/s00268-005-0464-4
223 rdf:type schema:CreativeWork
224 sg:pub.10.1016/j.gassur.2006.08.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031265211
225 https://doi.org/10.1016/j.gassur.2006.08.018
226 rdf:type schema:CreativeWork
227 sg:pub.10.1016/s1091-255x(01)80060-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016526318
228 https://doi.org/10.1016/s1091-255x(01)80060-3
229 rdf:type schema:CreativeWork
230 sg:pub.10.1245/aso.2003.02.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040268392
231 https://doi.org/10.1245/aso.2003.02.003
232 rdf:type schema:CreativeWork
233 sg:pub.10.1245/s10434-007-9782-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043465975
234 https://doi.org/10.1245/s10434-007-9782-0
235 rdf:type schema:CreativeWork
236 https://app.dimensions.ai/details/publication/pub.1074953939 schema:CreativeWork
237 https://app.dimensions.ai/details/publication/pub.1075760861 schema:CreativeWork
238 https://app.dimensions.ai/details/publication/pub.1076511279 schema:CreativeWork
239 https://app.dimensions.ai/details/publication/pub.1079458389 schema:CreativeWork
240 https://app.dimensions.ai/details/publication/pub.1079947413 schema:CreativeWork
241 https://app.dimensions.ai/details/publication/pub.1080109709 schema:CreativeWork
242 https://app.dimensions.ai/details/publication/pub.1081738592 schema:CreativeWork
243 https://app.dimensions.ai/details/publication/pub.1082485139 schema:CreativeWork
244 https://doi.org/10.1001/archsurg.133.4.413 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028847017
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1001/archsurg.141.6.537 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028598361
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1002/1097-0142(19881001)62:7<1397::aid-cncr2820620726>3.0.co;2-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050220448
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1002/bjs.1800800837 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015971048
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1002/jso.10262 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041191922
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1016/0002-9610(78)90072-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010882949
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1016/s0090-4295(00)00639-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022939699
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1097/01.sla.0000133083.54934.ae schema:sameAs https://app.dimensions.ai/details/publication/pub.1024049438
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1111/j.1440-1746.2007.05178.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019382229
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1159/000134475 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051054166
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1200/jco.2004.06.132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022235480
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1378/chest.73.2.163 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030920964
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1378/chest.84.4.442 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040966174
269 rdf:type schema:CreativeWork
270 https://doi.org/10.4065/75.6.581 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022960284
271 rdf:type schema:CreativeWork
272 https://www.grid.ac/institutes/grid.21107.35 schema:alternateName Johns Hopkins University
273 schema:name Department of Oncology, The Johns Hopkins University, 21287, Baltimore, Maryland, USA
274 Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University, 21287, Baltimore, Maryland, USA
275 Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, 21287, Baltimore, Maryland, USA
276 The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University, 21287, Baltimore, Maryland, USA
277 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...