N-Ratio: a Novel Independent Prognostic Factor for Patients with Stage-III Cutaneous Melanoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-01

AUTHORS

Carlo Riccardo Rossi, Simone Mocellin, Sandro Pasquali, Pierluigi Pilati, Donato Nitti

ABSTRACT

BACKGROUND: In this study, we tested the hypothesis that the ratio between metastatic and excised lymph nodes ("N-ratio") might have an independent prognostic value in patients with TNM stage-III cutaneous melanoma. METHODS: The clinical records of 213 melanoma patients who had undergone radical lymph node dissection (RLND) and were found to harbor pathology-proven metastatic disease were used for analysis. The following clinico-pathological variables were considered for the prognostic study: patient's age and sex, primary tumor site, tumor thickness, Clark's level, ulceration, absolute number of positive lymph nodes, total number of excised lymph nodes, TNM stage (IIIA, IIIB, IIIC), and N-ratio (N-ratio A, 25%). RESULTS: Patients were categorized into three N-ratio classes according to the percentage of metastatic lymph nodes (N-ratio A, n = 94; N-ratio B, n = 95; N-ratio C, n = 24). The mean follow-up was 40 months. At univariate survival analysis, tumor thickness (P < 0.0001), ulceration (P = 0.046), Clark's level (P = 0.0002), number of positive lymph nodes (P < 0.0001), TNM stage (P < 0.0001), and N-ratio (P < 0.0001) were significantly associated with overall survival (OS). Interestingly, the Cox proportional hazard model showed that, along with tumor thickness (HR 1.069, P = 0.008) and TNM stage (HR 1.696, P = 0.015), N-ratio (HR 1.578, P = 0.012) also independently predicted OS. CONCLUSIONS: N-ratio is a novel easy-to-obtain independent prognostic factor for melanoma patients with lymph node metastases and might provide clinicians with additional information suitable for patient stratification while choosing adjuvant treatment. Validation of these results in larger prospective series is warranted to implement N-ratio in the routine clinical setting. More... »

PAGES

310-315

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1245/s10434-007-9641-z

DOI

http://dx.doi.org/10.1245/s10434-007-9641-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012128915

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17987346


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymph Node Excision", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymph Nodes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymphatic Metastasis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Melanoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Staging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sentinel Lymph Node Biopsy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Skin Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Padua", 
          "id": "https://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Department of Oncological & Surgical Sciences, University of Padova, via Giustiniani 2, 35128, Padova, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rossi", 
        "givenName": "Carlo Riccardo", 
        "id": "sg:person.013321165112.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013321165112.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Padua", 
          "id": "https://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Department of Oncological & Surgical Sciences, University of Padova, via Giustiniani 2, 35128, Padova, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mocellin", 
        "givenName": "Simone", 
        "id": "sg:person.01370531503.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370531503.96"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Padua", 
          "id": "https://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Department of Oncological & Surgical Sciences, University of Padova, via Giustiniani 2, 35128, Padova, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pasquali", 
        "givenName": "Sandro", 
        "id": "sg:person.0761657243.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761657243.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Padua", 
          "id": "https://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Department of Oncological & Surgical Sciences, University of Padova, via Giustiniani 2, 35128, Padova, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pilati", 
        "givenName": "Pierluigi", 
        "id": "sg:person.01013644041.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01013644041.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Padua", 
          "id": "https://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Department of Oncological & Surgical Sciences, University of Padova, via Giustiniani 2, 35128, Padova, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nitti", 
        "givenName": "Donato", 
        "id": "sg:person.0664577705.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664577705.70"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.3322/canjclin.54.3.131", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001163810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejso.2006.06.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002570700"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmra041245", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005930121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.21372", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015836070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.21372", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015836070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.21760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017305622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.21760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017305622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejso.2006.04.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020116714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/aso.2003.03.520", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027442779", 
          "https://doi.org/10.1245/aso.2003.03.520"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/aso.2003.03.520", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027442779", 
          "https://doi.org/10.1245/aso.2003.03.520"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa053007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027682287"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0305-7372(03)00074-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028203404"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0305-7372(03)00074-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028203404"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000250423.43436.e1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031018286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000250423.43436.e1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031018286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(05)17951-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031814210"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35020115", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039076321", 
          "https://doi.org/10.1038/35020115"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35020115", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039076321", 
          "https://doi.org/10.1038/35020115"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1072-7515(00)00313-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040348154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2005.03.1526", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042929385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-1103-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044850066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2002.07.070", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064203028"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2001.19.16.3622", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074864906"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2001.19.16.3635", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074864907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076818531", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076984875", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000150157.83537.53", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1076984875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000150157.83537.53", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1076984875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000150157.83537.53", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1076984875"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-01", 
    "datePublishedReg": "2008-01-01", 
    "description": "BACKGROUND: In this study, we tested the hypothesis that the ratio between metastatic and excised lymph nodes (\"N-ratio\") might have an independent prognostic value in patients with TNM stage-III cutaneous melanoma.\nMETHODS: The clinical records of 213 melanoma patients who had undergone radical lymph node dissection (RLND) and were found to harbor pathology-proven metastatic disease were used for analysis. The following clinico-pathological variables were considered for the prognostic study: patient's age and sex, primary tumor site, tumor thickness, Clark's level, ulceration, absolute number of positive lymph nodes, total number of excised lymph nodes, TNM stage (IIIA, IIIB, IIIC), and N-ratio (N-ratio A, 25%).\nRESULTS: Patients were categorized into three N-ratio classes according to the percentage of metastatic lymph nodes (N-ratio A, n = 94; N-ratio B, n = 95; N-ratio C, n = 24). The mean follow-up was 40 months. At univariate survival analysis, tumor thickness (P < 0.0001), ulceration (P = 0.046), Clark's level (P = 0.0002), number of positive lymph nodes (P < 0.0001), TNM stage (P < 0.0001), and N-ratio (P < 0.0001) were significantly associated with overall survival (OS). Interestingly, the Cox proportional hazard model showed that, along with tumor thickness (HR 1.069, P = 0.008) and TNM stage (HR 1.696, P = 0.015), N-ratio (HR 1.578, P = 0.012) also independently predicted OS.\nCONCLUSIONS: N-ratio is a novel easy-to-obtain independent prognostic factor for melanoma patients with lymph node metastases and might provide clinicians with additional information suitable for patient stratification while choosing adjuvant treatment. Validation of these results in larger prospective series is warranted to implement N-ratio in the routine clinical setting.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1245/s10434-007-9641-z", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1105545", 
        "issn": [
          "1068-9265", 
          "1534-4681"
        ], 
        "name": "Annals of Surgical Oncology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "15"
      }
    ], 
    "name": "N-Ratio: a Novel Independent Prognostic Factor for Patients with Stage-III Cutaneous Melanoma", 
    "pagination": "310-315", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "39c922d01429dbbf47ed8444f15055347c979ff70a549ed2277903a584604cac"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "17987346"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9420840"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1245/s10434-007-9641-z"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1012128915"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1245/s10434-007-9641-z", 
      "https://app.dimensions.ai/details/publication/pub.1012128915"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000498.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1245/s10434-007-9641-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1245/s10434-007-9641-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1245/s10434-007-9641-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1245/s10434-007-9641-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1245/s10434-007-9641-z'


 

This table displays all metadata directly associated to this object as RDF triples.

216 TRIPLES      21 PREDICATES      64 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1245/s10434-007-9641-z schema:about N029df5f194264ee99ecec2832894ae88
2 N1b6bfd97509e4e988e4f6bf24eab6dde
3 N274b97513f414f7986b4cb1521e0527f
4 N2d6e11cb80d84f039bd5a948456a8ba2
5 N3285f88ef4d44177b113b7428731e3b3
6 N3b56b10f64ea4c138891cc903e2fbf04
7 N3f56b6b2454943a88be5ee4082d8518d
8 N4efb0f87231148e79b42033c441742c3
9 N7145ce0a450644978c8e49ddb8c11655
10 N85a8802fc8994f8e90d818918795f443
11 Nd682446595484e0f835622122a78adf4
12 Nda5a92ceca914d8abbc38935f4043e46
13 Ne08c3a52435c481ba9a8224d69850602
14 Nf901bdc990544e8ab69663c0c2276b0e
15 anzsrc-for:11
16 anzsrc-for:1112
17 schema:author N222f0bbadd014e45addcf2f9c57ea48b
18 schema:citation sg:pub.10.1038/35020115
19 sg:pub.10.1245/aso.2003.03.520
20 https://app.dimensions.ai/details/publication/pub.1076818531
21 https://app.dimensions.ai/details/publication/pub.1076984875
22 https://doi.org/10.1002/cncr.21372
23 https://doi.org/10.1002/cncr.21760
24 https://doi.org/10.1016/j.ejso.2006.04.004
25 https://doi.org/10.1016/j.ejso.2006.06.005
26 https://doi.org/10.1016/s0140-6736(05)17951-3
27 https://doi.org/10.1016/s0305-7372(03)00074-4
28 https://doi.org/10.1016/s1072-7515(00)00313-6
29 https://doi.org/10.1056/nejmoa053007
30 https://doi.org/10.1056/nejmra041245
31 https://doi.org/10.1097/01.sla.0000150157.83537.53
32 https://doi.org/10.1097/01.sla.0000250423.43436.e1
33 https://doi.org/10.1158/1078-0432.ccr-1103-3
34 https://doi.org/10.1200/jco.2001.19.16.3622
35 https://doi.org/10.1200/jco.2001.19.16.3635
36 https://doi.org/10.1200/jco.2002.07.070
37 https://doi.org/10.1200/jco.2005.03.1526
38 https://doi.org/10.3322/canjclin.54.3.131
39 schema:datePublished 2008-01
40 schema:datePublishedReg 2008-01-01
41 schema:description BACKGROUND: In this study, we tested the hypothesis that the ratio between metastatic and excised lymph nodes ("N-ratio") might have an independent prognostic value in patients with TNM stage-III cutaneous melanoma. METHODS: The clinical records of 213 melanoma patients who had undergone radical lymph node dissection (RLND) and were found to harbor pathology-proven metastatic disease were used for analysis. The following clinico-pathological variables were considered for the prognostic study: patient's age and sex, primary tumor site, tumor thickness, Clark's level, ulceration, absolute number of positive lymph nodes, total number of excised lymph nodes, TNM stage (IIIA, IIIB, IIIC), and N-ratio (N-ratio A, </=10%; N-ratio B, 10-25%; N-ratio C, >25%). RESULTS: Patients were categorized into three N-ratio classes according to the percentage of metastatic lymph nodes (N-ratio A, n = 94; N-ratio B, n = 95; N-ratio C, n = 24). The mean follow-up was 40 months. At univariate survival analysis, tumor thickness (P < 0.0001), ulceration (P = 0.046), Clark's level (P = 0.0002), number of positive lymph nodes (P < 0.0001), TNM stage (P < 0.0001), and N-ratio (P < 0.0001) were significantly associated with overall survival (OS). Interestingly, the Cox proportional hazard model showed that, along with tumor thickness (HR 1.069, P = 0.008) and TNM stage (HR 1.696, P = 0.015), N-ratio (HR 1.578, P = 0.012) also independently predicted OS. CONCLUSIONS: N-ratio is a novel easy-to-obtain independent prognostic factor for melanoma patients with lymph node metastases and might provide clinicians with additional information suitable for patient stratification while choosing adjuvant treatment. Validation of these results in larger prospective series is warranted to implement N-ratio in the routine clinical setting.
42 schema:genre research_article
43 schema:inLanguage en
44 schema:isAccessibleForFree false
45 schema:isPartOf N19231987d5f84df4ae571833f9156446
46 N3ddaad9e110f47678ee6d9f225315b0c
47 sg:journal.1105545
48 schema:name N-Ratio: a Novel Independent Prognostic Factor for Patients with Stage-III Cutaneous Melanoma
49 schema:pagination 310-315
50 schema:productId N0e8df460df8e49ce912866c937faacbb
51 N43adfeaa5b71441394af72e1c14b239c
52 N496351f2ff2f45808b1c737e4107b682
53 N71b7e156506746d3829b42f68c58d5d5
54 N77a9a522c563495dae72322304b670fa
55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012128915
56 https://doi.org/10.1245/s10434-007-9641-z
57 schema:sdDatePublished 2019-04-10T16:39
58 schema:sdLicense https://scigraph.springernature.com/explorer/license/
59 schema:sdPublisher Nce4b385248d7492faaeacd0eee0093e9
60 schema:url http://link.springer.com/10.1245/s10434-007-9641-z
61 sgo:license sg:explorer/license/
62 sgo:sdDataset articles
63 rdf:type schema:ScholarlyArticle
64 N029df5f194264ee99ecec2832894ae88 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
65 schema:name Treatment Outcome
66 rdf:type schema:DefinedTerm
67 N0e8df460df8e49ce912866c937faacbb schema:name doi
68 schema:value 10.1245/s10434-007-9641-z
69 rdf:type schema:PropertyValue
70 N19231987d5f84df4ae571833f9156446 schema:volumeNumber 15
71 rdf:type schema:PublicationVolume
72 N1b6bfd97509e4e988e4f6bf24eab6dde schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Lymphatic Metastasis
74 rdf:type schema:DefinedTerm
75 N222f0bbadd014e45addcf2f9c57ea48b rdf:first sg:person.013321165112.41
76 rdf:rest N501e262b3bcb453ea4d5d8be1d92d13f
77 N274b97513f414f7986b4cb1521e0527f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Lymph Nodes
79 rdf:type schema:DefinedTerm
80 N2d6e11cb80d84f039bd5a948456a8ba2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Neoplasm Staging
82 rdf:type schema:DefinedTerm
83 N3285f88ef4d44177b113b7428731e3b3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Sentinel Lymph Node Biopsy
85 rdf:type schema:DefinedTerm
86 N3b56b10f64ea4c138891cc903e2fbf04 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Prognosis
88 rdf:type schema:DefinedTerm
89 N3ddaad9e110f47678ee6d9f225315b0c schema:issueNumber 1
90 rdf:type schema:PublicationIssue
91 N3f56b6b2454943a88be5ee4082d8518d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Male
93 rdf:type schema:DefinedTerm
94 N43adfeaa5b71441394af72e1c14b239c schema:name pubmed_id
95 schema:value 17987346
96 rdf:type schema:PropertyValue
97 N496351f2ff2f45808b1c737e4107b682 schema:name nlm_unique_id
98 schema:value 9420840
99 rdf:type schema:PropertyValue
100 N4efb0f87231148e79b42033c441742c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Lymph Node Excision
102 rdf:type schema:DefinedTerm
103 N501e262b3bcb453ea4d5d8be1d92d13f rdf:first sg:person.01370531503.96
104 rdf:rest Nce3689c4bae548258cdcee1b97592a0a
105 N7145ce0a450644978c8e49ddb8c11655 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Survival Rate
107 rdf:type schema:DefinedTerm
108 N71b7e156506746d3829b42f68c58d5d5 schema:name dimensions_id
109 schema:value pub.1012128915
110 rdf:type schema:PropertyValue
111 N77a9a522c563495dae72322304b670fa schema:name readcube_id
112 schema:value 39c922d01429dbbf47ed8444f15055347c979ff70a549ed2277903a584604cac
113 rdf:type schema:PropertyValue
114 N7ce9d1cbef0948f192f3fee481456ccd rdf:first sg:person.0664577705.70
115 rdf:rest rdf:nil
116 N85a8802fc8994f8e90d818918795f443 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Melanoma
118 rdf:type schema:DefinedTerm
119 Nbc59d677780143dab6af147539731860 rdf:first sg:person.01013644041.08
120 rdf:rest N7ce9d1cbef0948f192f3fee481456ccd
121 Nce3689c4bae548258cdcee1b97592a0a rdf:first sg:person.0761657243.34
122 rdf:rest Nbc59d677780143dab6af147539731860
123 Nce4b385248d7492faaeacd0eee0093e9 schema:name Springer Nature - SN SciGraph project
124 rdf:type schema:Organization
125 Nd682446595484e0f835622122a78adf4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Humans
127 rdf:type schema:DefinedTerm
128 Nda5a92ceca914d8abbc38935f4043e46 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Skin Neoplasms
130 rdf:type schema:DefinedTerm
131 Ne08c3a52435c481ba9a8224d69850602 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Middle Aged
133 rdf:type schema:DefinedTerm
134 Nf901bdc990544e8ab69663c0c2276b0e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Female
136 rdf:type schema:DefinedTerm
137 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
138 schema:name Medical and Health Sciences
139 rdf:type schema:DefinedTerm
140 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
141 schema:name Oncology and Carcinogenesis
142 rdf:type schema:DefinedTerm
143 sg:journal.1105545 schema:issn 1068-9265
144 1534-4681
145 schema:name Annals of Surgical Oncology
146 rdf:type schema:Periodical
147 sg:person.01013644041.08 schema:affiliation https://www.grid.ac/institutes/grid.5608.b
148 schema:familyName Pilati
149 schema:givenName Pierluigi
150 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01013644041.08
151 rdf:type schema:Person
152 sg:person.013321165112.41 schema:affiliation https://www.grid.ac/institutes/grid.5608.b
153 schema:familyName Rossi
154 schema:givenName Carlo Riccardo
155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013321165112.41
156 rdf:type schema:Person
157 sg:person.01370531503.96 schema:affiliation https://www.grid.ac/institutes/grid.5608.b
158 schema:familyName Mocellin
159 schema:givenName Simone
160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370531503.96
161 rdf:type schema:Person
162 sg:person.0664577705.70 schema:affiliation https://www.grid.ac/institutes/grid.5608.b
163 schema:familyName Nitti
164 schema:givenName Donato
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664577705.70
166 rdf:type schema:Person
167 sg:person.0761657243.34 schema:affiliation https://www.grid.ac/institutes/grid.5608.b
168 schema:familyName Pasquali
169 schema:givenName Sandro
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761657243.34
171 rdf:type schema:Person
172 sg:pub.10.1038/35020115 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039076321
173 https://doi.org/10.1038/35020115
174 rdf:type schema:CreativeWork
175 sg:pub.10.1245/aso.2003.03.520 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027442779
176 https://doi.org/10.1245/aso.2003.03.520
177 rdf:type schema:CreativeWork
178 https://app.dimensions.ai/details/publication/pub.1076818531 schema:CreativeWork
179 https://app.dimensions.ai/details/publication/pub.1076984875 schema:CreativeWork
180 https://doi.org/10.1002/cncr.21372 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015836070
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1002/cncr.21760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017305622
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1016/j.ejso.2006.04.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020116714
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/j.ejso.2006.06.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002570700
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1016/s0140-6736(05)17951-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031814210
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/s0305-7372(03)00074-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028203404
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1016/s1072-7515(00)00313-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040348154
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1056/nejmoa053007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027682287
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1056/nejmra041245 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005930121
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1097/01.sla.0000150157.83537.53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076984875
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1097/01.sla.0000250423.43436.e1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031018286
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1158/1078-0432.ccr-1103-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044850066
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1200/jco.2001.19.16.3622 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074864906
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1200/jco.2001.19.16.3635 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074864907
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1200/jco.2002.07.070 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064203028
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1200/jco.2005.03.1526 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042929385
211 rdf:type schema:CreativeWork
212 https://doi.org/10.3322/canjclin.54.3.131 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001163810
213 rdf:type schema:CreativeWork
214 https://www.grid.ac/institutes/grid.5608.b schema:alternateName University of Padua
215 schema:name Department of Oncological & Surgical Sciences, University of Padova, via Giustiniani 2, 35128, Padova, Italy
216 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...