IL-1α Causes Lung Inflammation and Maturation by Direct Effects on Preterm Fetal Lamb Lungs View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-09

AUTHORS

ILENE R.S. SOSENKO, SUHAS G. KALLAPUR, ILIAS NITSOS, TIMOTHY J.M. MOSS, JOHN P. NEWNHAM, MACHIKO IKEGAMI, ALAN H. JOBE

ABSTRACT

Intra-amniotic endotoxin induces IL-1, causes chorioamnionitis, lung inflammation, lung injury and lung maturation in preterm lambs. Intra-amniotic IL-1alpha also causes chorioamnionitis, lung inflammation and lung maturation. We asked if IL-1alpha effects on the preterm lung are mediated by direct signaling to the lung rather than by indirect effects from the chorioamnionitis. To study IL-1 effects independently of chorioamnionitis, the lungs and the amniotic fluid were surgically separated in fetal sheep by diverting fetal lung fluid via a tracheostomy tube to a sialastic bag. A mini-osmotic pump delivered an intratracheal infusion of recombinant sheep IL-1alpha (10 microg) or saline (control) over 24 h. Preterm lambs were delivered 1d or 7d after the start of the infusion at 124d gestational age (Term = 150d). IL-1alpha recruited inflammatory cells and increased pro-inflammatory cytokine mRNA expression in the fetal lungs. Compared with controls, IL-1alpha did not alter lung antioxidant enzyme activity or alveolar numbers. IL-1alpha had minimal effects on the mRNA or protein expression of proteins essential for vascular development. IL-1alpha induced large increases in alveolar surfactant saturated phosphatidylcholine and increased lung gas volumes. Lung inflammation and maturation result from direct exposure of the fetal lung to a single cytokine - IL-1alpha. More... »

PAGES

294-298

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/01.pdr.0000233115.51309.d3

DOI

http://dx.doi.org/10.1203/01.pdr.0000233115.51309.d3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040751247

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16857758


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1114", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Paediatrics and Reproductive Medicine", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fetus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Inflammation Mediators", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infusion Pumps", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interleukin-1", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interleukin-1alpha", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lung", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pregnancy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Premature Birth", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombinant Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sheep", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "SOSENKO", 
        "givenName": "ILENE R.S.", 
        "id": "sg:person.01304006177.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304006177.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "KALLAPUR", 
        "givenName": "SUHAS G.", 
        "id": "sg:person.013401121337.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013401121337.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "NITSOS", 
        "givenName": "ILIAS", 
        "id": "sg:person.01222440305.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222440305.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "MOSS", 
        "givenName": "TIMOTHY J.M.", 
        "id": "sg:person.0663370127.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0663370127.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "NEWNHAM", 
        "givenName": "JOHN P.", 
        "id": "sg:person.01021220240.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021220240.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "IKEGAMI", 
        "givenName": "MACHIKO", 
        "id": "sg:person.0664202371.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664202371.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "JOBE", 
        "givenName": "ALAN H.", 
        "id": "sg:person.01012472572.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012472572.05"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0014-5793(70)80488-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000617113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.162.5.2003044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001063091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/s0002-9378(03)00758-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004907138"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/00006450-200012000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005259346", 
          "https://doi.org/10.1203/00006450-200012000-00014"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/00006450-200012000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005259346", 
          "https://doi.org/10.1203/00006450-200012000-00014"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/00006450-200209000-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007932735", 
          "https://doi.org/10.1203/00006450-200209000-00008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.200506-1007oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008228702"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.200506-1007oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008228702"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajplung.00389.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012618173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(87)80300-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015964737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm200005183422007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017548540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/00006450-198607000-00019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017719076", 
          "https://doi.org/10.1203/00006450-198607000-00019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajog.2004.11.063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018927930"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.200406-745oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021782960"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mob.2002.126296", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024095377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mob.2002.126296", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024095377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2567.2004.01976.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026482372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajog.2005.03.065", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027361743"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1074-7613(00)80596-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028440125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(00)90004-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030050153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mpd.2002.121381", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035387369"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mpd.2002.121381", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035387369"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/01.pdr.0000055769.19891.c4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036622056", 
          "https://doi.org/10.1203/01.pdr.0000055769.19891.c4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/01.pdr.0000055769.19891.c4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036622056", 
          "https://doi.org/10.1203/01.pdr.0000055769.19891.c4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.2203030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038541960"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.164.6.2103061", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039007696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-2697(74)90091-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040488478"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/ar1469", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042600368", 
          "https://doi.org/10.1186/ar1469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9378(97)70276-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050553740"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9378(97)70276-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050553740"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajplung.00049.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052110582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000047044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053654767"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajplung.00097.2001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063195127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajplung.00393.2002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063195695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajplung.2001.280.3.l527", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074751186"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075899331", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpregu.1987.253.4.r592", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079883400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081043150", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081149458", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081547057", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082869131", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083157420", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jappl.1998.85.1.273", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083287719"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2006-09", 
    "datePublishedReg": "2006-09-01", 
    "description": "Intra-amniotic endotoxin induces IL-1, causes chorioamnionitis, lung inflammation, lung injury and lung maturation in preterm lambs. Intra-amniotic IL-1alpha also causes chorioamnionitis, lung inflammation and lung maturation. We asked if IL-1alpha effects on the preterm lung are mediated by direct signaling to the lung rather than by indirect effects from the chorioamnionitis. To study IL-1 effects independently of chorioamnionitis, the lungs and the amniotic fluid were surgically separated in fetal sheep by diverting fetal lung fluid via a tracheostomy tube to a sialastic bag. A mini-osmotic pump delivered an intratracheal infusion of recombinant sheep IL-1alpha (10 microg) or saline (control) over 24 h. Preterm lambs were delivered 1d or 7d after the start of the infusion at 124d gestational age (Term = 150d). IL-1alpha recruited inflammatory cells and increased pro-inflammatory cytokine mRNA expression in the fetal lungs. Compared with controls, IL-1alpha did not alter lung antioxidant enzyme activity or alveolar numbers. IL-1alpha had minimal effects on the mRNA or protein expression of proteins essential for vascular development. IL-1alpha induced large increases in alveolar surfactant saturated phosphatidylcholine and increased lung gas volumes. Lung inflammation and maturation result from direct exposure of the fetal lung to a single cytokine - IL-1alpha.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1203/01.pdr.0000233115.51309.d3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2414015", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2537589", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1007352", 
        "issn": [
          "0031-3998", 
          "1530-0447"
        ], 
        "name": "Pediatric Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "60"
      }
    ], 
    "name": "IL-1\u03b1 Causes Lung Inflammation and Maturation by Direct Effects on Preterm Fetal Lamb Lungs", 
    "pagination": "294-298", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "c21f4948a2763642ff89ab5a84fc7ba2fa7781db981e7a5328d90d532672f046"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "16857758"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0100714"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1203/01.pdr.0000233115.51309.d3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1040751247"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1203/01.pdr.0000233115.51309.d3", 
      "https://app.dimensions.ai/details/publication/pub.1040751247"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T11:34", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000358_0000000358/records_127422_00000006.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=0006450-200609000-00010"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1203/01.pdr.0000233115.51309.d3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1203/01.pdr.0000233115.51309.d3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1203/01.pdr.0000233115.51309.d3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1203/01.pdr.0000233115.51309.d3'


 

This table displays all metadata directly associated to this object as RDF triples.

284 TRIPLES      21 PREDICATES      78 URIs      33 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1203/01.pdr.0000233115.51309.d3 schema:about N06d661b67f2349439c2e1b4ca34a3636
2 N1ad5bb2f72e54225b235ab92b971d03f
3 N2ad7763538bf4f89944fc1129da2d8f7
4 N52673181f27a40dc8f398362974a47f0
5 N54e9ba48bfb84288a7ddfa926ebfc61d
6 N5b9a258f11b74174913e84996593561c
7 N616e9f6547684852a7c432656e6cae41
8 N6d823dcb4c764333805433f8cf775ba5
9 N8358f693d65d427a95d40484037fa830
10 N8482466425324682ab48ab0c1045f0d4
11 N98de8c4021374ee28f08c1bd0c5320bc
12 Na5c752d379cf4b14a869bc5f0f28aede
13 anzsrc-for:11
14 anzsrc-for:1114
15 schema:author N38ab50bd791d4e0aadd422e57075871d
16 schema:citation sg:pub.10.1186/ar1469
17 sg:pub.10.1203/00006450-198607000-00019
18 sg:pub.10.1203/00006450-200012000-00014
19 sg:pub.10.1203/00006450-200209000-00008
20 sg:pub.10.1203/01.pdr.0000055769.19891.c4
21 https://app.dimensions.ai/details/publication/pub.1075899331
22 https://app.dimensions.ai/details/publication/pub.1081043150
23 https://app.dimensions.ai/details/publication/pub.1081149458
24 https://app.dimensions.ai/details/publication/pub.1081547057
25 https://app.dimensions.ai/details/publication/pub.1082869131
26 https://app.dimensions.ai/details/publication/pub.1083157420
27 https://doi.org/10.1016/0003-2697(74)90091-8
28 https://doi.org/10.1016/0014-5793(70)80488-4
29 https://doi.org/10.1016/j.ajog.2004.11.063
30 https://doi.org/10.1016/j.ajog.2005.03.065
31 https://doi.org/10.1016/s0002-9378(97)70276-x
32 https://doi.org/10.1016/s0022-3476(00)90004-0
33 https://doi.org/10.1016/s0022-3476(87)80300-1
34 https://doi.org/10.1016/s1074-7613(00)80596-8
35 https://doi.org/10.1056/nejm200005183422007
36 https://doi.org/10.1067/mob.2002.126296
37 https://doi.org/10.1067/mpd.2002.121381
38 https://doi.org/10.1067/s0002-9378(03)00758-0
39 https://doi.org/10.1111/j.1365-2567.2004.01976.x
40 https://doi.org/10.1152/ajplung.00049.2004
41 https://doi.org/10.1152/ajplung.00097.2001
42 https://doi.org/10.1152/ajplung.00389.2004
43 https://doi.org/10.1152/ajplung.00393.2002
44 https://doi.org/10.1152/ajplung.2001.280.3.l527
45 https://doi.org/10.1152/ajpregu.1987.253.4.r592
46 https://doi.org/10.1152/jappl.1998.85.1.273
47 https://doi.org/10.1159/000047044
48 https://doi.org/10.1164/ajrccm.162.5.2003044
49 https://doi.org/10.1164/ajrccm.164.6.2103061
50 https://doi.org/10.1164/rccm.200406-745oc
51 https://doi.org/10.1164/rccm.200506-1007oc
52 https://doi.org/10.1164/rccm.2203030
53 schema:datePublished 2006-09
54 schema:datePublishedReg 2006-09-01
55 schema:description Intra-amniotic endotoxin induces IL-1, causes chorioamnionitis, lung inflammation, lung injury and lung maturation in preterm lambs. Intra-amniotic IL-1alpha also causes chorioamnionitis, lung inflammation and lung maturation. We asked if IL-1alpha effects on the preterm lung are mediated by direct signaling to the lung rather than by indirect effects from the chorioamnionitis. To study IL-1 effects independently of chorioamnionitis, the lungs and the amniotic fluid were surgically separated in fetal sheep by diverting fetal lung fluid via a tracheostomy tube to a sialastic bag. A mini-osmotic pump delivered an intratracheal infusion of recombinant sheep IL-1alpha (10 microg) or saline (control) over 24 h. Preterm lambs were delivered 1d or 7d after the start of the infusion at 124d gestational age (Term = 150d). IL-1alpha recruited inflammatory cells and increased pro-inflammatory cytokine mRNA expression in the fetal lungs. Compared with controls, IL-1alpha did not alter lung antioxidant enzyme activity or alveolar numbers. IL-1alpha had minimal effects on the mRNA or protein expression of proteins essential for vascular development. IL-1alpha induced large increases in alveolar surfactant saturated phosphatidylcholine and increased lung gas volumes. Lung inflammation and maturation result from direct exposure of the fetal lung to a single cytokine - IL-1alpha.
56 schema:genre research_article
57 schema:inLanguage en
58 schema:isAccessibleForFree true
59 schema:isPartOf N705f548a8146435abd28801416d185e9
60 Nac369817d7ec49afb50c8776d75847fa
61 sg:journal.1007352
62 schema:name IL-1α Causes Lung Inflammation and Maturation by Direct Effects on Preterm Fetal Lamb Lungs
63 schema:pagination 294-298
64 schema:productId N556f2a746e3c4e7b9b491cf9b36af196
65 N75bc403fc0d14dcc959182f4c79c3091
66 N7e75134b035a4d0e95f808b93952332d
67 Na1cd008fde26409f90f1a9521a7b6a3c
68 Nc5a655eacfb548619f8e7bc372e1ccc2
69 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040751247
70 https://doi.org/10.1203/01.pdr.0000233115.51309.d3
71 schema:sdDatePublished 2019-04-11T11:34
72 schema:sdLicense https://scigraph.springernature.com/explorer/license/
73 schema:sdPublisher Na9b9958204af4303ab62fa1af1ada6be
74 schema:url http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=0006450-200609000-00010
75 sgo:license sg:explorer/license/
76 sgo:sdDataset articles
77 rdf:type schema:ScholarlyArticle
78 N06d661b67f2349439c2e1b4ca34a3636 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Pregnancy
80 rdf:type schema:DefinedTerm
81 N0970ed2aa36d4aa198814d1315886a38 schema:name Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia
82 rdf:type schema:Organization
83 N0d093a0951fb431ba27ba11a8fcfece9 rdf:first sg:person.01222440305.31
84 rdf:rest Nbc2f70df88da4c90a21e174f77479703
85 N15e1c4665f7a4d9db16eba4a1755477c rdf:first sg:person.01021220240.90
86 rdf:rest N6e55630d79fc42238c6d9d563a752bfa
87 N1ad5bb2f72e54225b235ab92b971d03f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Recombinant Proteins
89 rdf:type schema:DefinedTerm
90 N21241b8d81a544c0afe51af54da7b18a schema:name Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia
91 rdf:type schema:Organization
92 N2ad7763538bf4f89944fc1129da2d8f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Sheep
94 rdf:type schema:DefinedTerm
95 N38ab50bd791d4e0aadd422e57075871d rdf:first sg:person.01304006177.19
96 rdf:rest Nd256400a1d6240b4bc8805dd7a758a84
97 N52673181f27a40dc8f398362974a47f0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Interleukin-1alpha
99 rdf:type schema:DefinedTerm
100 N54e9ba48bfb84288a7ddfa926ebfc61d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Infusion Pumps
102 rdf:type schema:DefinedTerm
103 N556f2a746e3c4e7b9b491cf9b36af196 schema:name doi
104 schema:value 10.1203/01.pdr.0000233115.51309.d3
105 rdf:type schema:PropertyValue
106 N5b9a258f11b74174913e84996593561c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Inflammation Mediators
108 rdf:type schema:DefinedTerm
109 N616e9f6547684852a7c432656e6cae41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Premature Birth
111 rdf:type schema:DefinedTerm
112 N6ac5ad33e2024ae0aa34c465c161ac6b schema:name Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia
113 rdf:type schema:Organization
114 N6d823dcb4c764333805433f8cf775ba5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Female
116 rdf:type schema:DefinedTerm
117 N6e55630d79fc42238c6d9d563a752bfa rdf:first sg:person.0664202371.48
118 rdf:rest N75c65aff7f0e4364ad83f203c9403674
119 N705f548a8146435abd28801416d185e9 schema:issueNumber 3
120 rdf:type schema:PublicationIssue
121 N75bc403fc0d14dcc959182f4c79c3091 schema:name nlm_unique_id
122 schema:value 0100714
123 rdf:type schema:PropertyValue
124 N75c65aff7f0e4364ad83f203c9403674 rdf:first sg:person.01012472572.05
125 rdf:rest rdf:nil
126 N7e75134b035a4d0e95f808b93952332d schema:name pubmed_id
127 schema:value 16857758
128 rdf:type schema:PropertyValue
129 N8358f693d65d427a95d40484037fa830 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Animals
131 rdf:type schema:DefinedTerm
132 N8482466425324682ab48ab0c1045f0d4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Interleukin-1
134 rdf:type schema:DefinedTerm
135 N98de8c4021374ee28f08c1bd0c5320bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Fetus
137 rdf:type schema:DefinedTerm
138 Na14fdef40ae94ceb87b00b10f1c1d25c schema:name Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia
139 rdf:type schema:Organization
140 Na1cd008fde26409f90f1a9521a7b6a3c schema:name readcube_id
141 schema:value c21f4948a2763642ff89ab5a84fc7ba2fa7781db981e7a5328d90d532672f046
142 rdf:type schema:PropertyValue
143 Na5c752d379cf4b14a869bc5f0f28aede schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Lung
145 rdf:type schema:DefinedTerm
146 Na8fb622f48224902afc6e1d34f4753db schema:name Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia
147 rdf:type schema:Organization
148 Na9b9958204af4303ab62fa1af1ada6be schema:name Springer Nature - SN SciGraph project
149 rdf:type schema:Organization
150 Nac369817d7ec49afb50c8776d75847fa schema:volumeNumber 60
151 rdf:type schema:PublicationVolume
152 Nb7b6f8d1b321437faa7aa4fea5c5cd0f schema:name Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia
153 rdf:type schema:Organization
154 Nbaead177aae74c439e68afe30587d233 schema:name Department of Pediatrics [I.R.S.S.], University of Miami School of Medicine, Miami, FL 33106; Division of Pulmonary Biology [S.G.K., MI, A.H.J.], Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229; School of Women's and Infants' Health [I.N., T.J.M.M., J.P.N.], The University of Western Australia, Crawley 6009, Western Australia, Australia
155 rdf:type schema:Organization
156 Nbc2f70df88da4c90a21e174f77479703 rdf:first sg:person.0663370127.99
157 rdf:rest N15e1c4665f7a4d9db16eba4a1755477c
158 Nc5a655eacfb548619f8e7bc372e1ccc2 schema:name dimensions_id
159 schema:value pub.1040751247
160 rdf:type schema:PropertyValue
161 Nd256400a1d6240b4bc8805dd7a758a84 rdf:first sg:person.013401121337.73
162 rdf:rest N0d093a0951fb431ba27ba11a8fcfece9
163 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
164 schema:name Medical and Health Sciences
165 rdf:type schema:DefinedTerm
166 anzsrc-for:1114 schema:inDefinedTermSet anzsrc-for:
167 schema:name Paediatrics and Reproductive Medicine
168 rdf:type schema:DefinedTerm
169 sg:grant.2414015 http://pending.schema.org/fundedItem sg:pub.10.1203/01.pdr.0000233115.51309.d3
170 rdf:type schema:MonetaryGrant
171 sg:grant.2537589 http://pending.schema.org/fundedItem sg:pub.10.1203/01.pdr.0000233115.51309.d3
172 rdf:type schema:MonetaryGrant
173 sg:journal.1007352 schema:issn 0031-3998
174 1530-0447
175 schema:name Pediatric Research
176 rdf:type schema:Periodical
177 sg:person.01012472572.05 schema:affiliation N6ac5ad33e2024ae0aa34c465c161ac6b
178 schema:familyName JOBE
179 schema:givenName ALAN H.
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012472572.05
181 rdf:type schema:Person
182 sg:person.01021220240.90 schema:affiliation N0970ed2aa36d4aa198814d1315886a38
183 schema:familyName NEWNHAM
184 schema:givenName JOHN P.
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021220240.90
186 rdf:type schema:Person
187 sg:person.01222440305.31 schema:affiliation Nb7b6f8d1b321437faa7aa4fea5c5cd0f
188 schema:familyName NITSOS
189 schema:givenName ILIAS
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222440305.31
191 rdf:type schema:Person
192 sg:person.01304006177.19 schema:affiliation Na14fdef40ae94ceb87b00b10f1c1d25c
193 schema:familyName SOSENKO
194 schema:givenName ILENE R.S.
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304006177.19
196 rdf:type schema:Person
197 sg:person.013401121337.73 schema:affiliation N21241b8d81a544c0afe51af54da7b18a
198 schema:familyName KALLAPUR
199 schema:givenName SUHAS G.
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013401121337.73
201 rdf:type schema:Person
202 sg:person.0663370127.99 schema:affiliation Nbaead177aae74c439e68afe30587d233
203 schema:familyName MOSS
204 schema:givenName TIMOTHY J.M.
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0663370127.99
206 rdf:type schema:Person
207 sg:person.0664202371.48 schema:affiliation Na8fb622f48224902afc6e1d34f4753db
208 schema:familyName IKEGAMI
209 schema:givenName MACHIKO
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664202371.48
211 rdf:type schema:Person
212 sg:pub.10.1186/ar1469 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042600368
213 https://doi.org/10.1186/ar1469
214 rdf:type schema:CreativeWork
215 sg:pub.10.1203/00006450-198607000-00019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017719076
216 https://doi.org/10.1203/00006450-198607000-00019
217 rdf:type schema:CreativeWork
218 sg:pub.10.1203/00006450-200012000-00014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005259346
219 https://doi.org/10.1203/00006450-200012000-00014
220 rdf:type schema:CreativeWork
221 sg:pub.10.1203/00006450-200209000-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007932735
222 https://doi.org/10.1203/00006450-200209000-00008
223 rdf:type schema:CreativeWork
224 sg:pub.10.1203/01.pdr.0000055769.19891.c4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036622056
225 https://doi.org/10.1203/01.pdr.0000055769.19891.c4
226 rdf:type schema:CreativeWork
227 https://app.dimensions.ai/details/publication/pub.1075899331 schema:CreativeWork
228 https://app.dimensions.ai/details/publication/pub.1081043150 schema:CreativeWork
229 https://app.dimensions.ai/details/publication/pub.1081149458 schema:CreativeWork
230 https://app.dimensions.ai/details/publication/pub.1081547057 schema:CreativeWork
231 https://app.dimensions.ai/details/publication/pub.1082869131 schema:CreativeWork
232 https://app.dimensions.ai/details/publication/pub.1083157420 schema:CreativeWork
233 https://doi.org/10.1016/0003-2697(74)90091-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040488478
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1016/0014-5793(70)80488-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000617113
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1016/j.ajog.2004.11.063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018927930
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1016/j.ajog.2005.03.065 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027361743
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1016/s0002-9378(97)70276-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050553740
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1016/s0022-3476(00)90004-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030050153
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1016/s0022-3476(87)80300-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015964737
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1016/s1074-7613(00)80596-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028440125
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1056/nejm200005183422007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017548540
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1067/mob.2002.126296 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024095377
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1067/mpd.2002.121381 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035387369
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1067/s0002-9378(03)00758-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004907138
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1111/j.1365-2567.2004.01976.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026482372
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1152/ajplung.00049.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052110582
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1152/ajplung.00097.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063195127
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1152/ajplung.00389.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012618173
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1152/ajplung.00393.2002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063195695
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1152/ajplung.2001.280.3.l527 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074751186
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1152/ajpregu.1987.253.4.r592 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079883400
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1152/jappl.1998.85.1.273 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083287719
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1159/000047044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053654767
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1164/ajrccm.162.5.2003044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001063091
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1164/ajrccm.164.6.2103061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039007696
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1164/rccm.200406-745oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1021782960
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1164/rccm.200506-1007oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1008228702
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1164/rccm.2203030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038541960
284 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...