1242 Impact of Pandemic H1N1 Virus Infection in An Paediatric Intensive Care Unit View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-11

AUTHORS

S Stabouli, A Violaki, J Dotis, M Mitroudi, S Kalamitsou, V Kotsis, M Kotsiou

ABSTRACT

Objective: To describe characteristics and outcomes of paediatric patients in a paediatric intensive care unit (PICU) during H1N1 pandemic.Patients and Methods: We included in the study 34 consecutive patients, admitted to the PICU from 01-11-2009 to 28-02-2010. Demographic data, symptoms, comorbid conditions, illness progression, treatments, and clinical outcomes were collected from all patients.Results: 19 (55.9%) patients were male and 15 (44.1%) were female. 29.4% of the patients were positive for H1N1 by viral polymerase chain reaction (PCR) on endobronchial secretions. Subjects with H1N1 infection were older than children who were admitted to the paediatric intensive care unit for other causes (7.9±5.1 years vs. 3.9±3.7 years, P< 0.05). Duration of intensive care stay and mechanical ventilation was longer in children with H1N1 infection (34.7±28.7 vs. 11.8±17.5 days, P< 0.05 and 32.5±27.7 vs. 10.3±18.6 days, P< 0.05, respectively). 80% of the children with H1N1 infection had known comordid disorders compared to the 33.3% of the rest of the subjects (P< 0.05). Children with H1N1 infection presented an increased complications rate (70% vs. 16.7%, P< 0.005) and had 4.8 times increased likelihood to present complications compared with the children who were admitted to the paediatric intensive care unit for other causes. Mortality rate was higher in children with H1N1 infection, but the difference between the two groups was not statistically significant.Conclusions: Critical illness from H1N1 infection in children who require admission to paediatric intensive care unit, was associated with increased complications rate, and prolonged duration of mechanical ventilation and hospitalization. More... »

PAGES

615-615

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-201011001-01242

DOI

http://dx.doi.org/10.1203/00006450-201011001-01242

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037277234


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