Frequent Low Level Expression in Ewing Sarcoma Family Tumors and Widespread Absence of the Metastasis Suppressor KAI1/CD82 in Neuroblastoma View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2002-08

AUTHORS

Dave N T Aryee, Inge Ambros, Peter F Ambros, Karin Muehlbacher, Andrea Luegmayr, Osamu Yoshie, Heinrich Kovar

ABSTRACT

The transmembrane 4 superfamily member KAI1/CD82, a metastasis suppressor, is correlated inversely with the progression and invasion of several tumors. It is capable of inhibiting metastasis without affecting tumorigenicity per se. KAI1/CD82 expression is down-regulated in the progression of common solid epithelial tumors of adulthood. Mutation of p53 is suggested to be involved in the modulation of KAI1. As little is known about its expression and possible prognostic impact in pediatric tumors, we investigated KAI1/CD82 expression in cell lines and primary tumor samples from pediatric tumors of neuroectodermal origin, neuroblastoma and Ewing's sarcoma family tumor. Twenty-four of 29 Ewing's sarcoma family tumor cell lines, independent of p53 status, showed KAI1 mRNA positivity by reverse transcription-PCR analysis in contrast to zero of eight neuroblastoma cell lines. Among 13 primary Ewing's sarcoma family tumor samples from patients with different disease extension, KAI1 mRNA expression was low as detected by reverse transcription-PCR. Twenty of 30 primary neuroblastoma specimens were KAI1-negative by immunofluorescence analysis whereas the remaining 10 gave weak to moderate staining patterns. There was no apparent correlation of KAI1 expression with any clinical or genetic features of the patients whose tumor samples were studied. Consequently, KAI1 may not be of prognostic relevance in this group of tumors although there may be some role for KAI1 modulation in the biology of these neuroectodermal tumors. More... »

PAGES

279-285

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-200208000-00022

DOI

http://dx.doi.org/10.1203/00006450-200208000-00022

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010230010

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12149507


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens, CD", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child, Preschool", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation, Neoplastic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Markers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kangai-1 Protein", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Membrane Glycoproteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuroblastoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogene Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sarcoma, Ewing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Cells, Cultured", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.416346.2", 
          "name": [
            "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aryee", 
        "givenName": "Dave N T", 
        "id": "sg:person.015406057707.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015406057707.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.416346.2", 
          "name": [
            "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ambros", 
        "givenName": "Inge", 
        "id": "sg:person.01112427340.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112427340.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.416346.2", 
          "name": [
            "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ambros", 
        "givenName": "Peter F", 
        "id": "sg:person.0674613533.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674613533.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.416346.2", 
          "name": [
            "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Muehlbacher", 
        "givenName": "Karin", 
        "id": "sg:person.01351015475.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351015475.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.416346.2", 
          "name": [
            "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Luegmayr", 
        "givenName": "Andrea", 
        "id": "sg:person.01161157702.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161157702.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Bacteriology, Kinki University School of Medicine, Osaka, Sayama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.258622.9", 
          "name": [
            "Department of Bacteriology, Kinki University School of Medicine, Osaka, Sayama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yoshie", 
        "givenName": "Osamu", 
        "id": "sg:person.01362270415.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362270415.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.416346.2", 
          "name": [
            "Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kovar", 
        "givenName": "Heinrich", 
        "id": "sg:person.0741362200.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741362200.35"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/labinvest.3780194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038836006", 
          "https://doi.org/10.1038/labinvest.3780194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1201852", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043222365", 
          "https://doi.org/10.1038/sj.onc.1201852"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1201397", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004676244", 
          "https://doi.org/10.1038/sj.onc.1201397"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2002-08", 
    "datePublishedReg": "2002-08-01", 
    "description": "The transmembrane 4 superfamily member KAI1/CD82, a metastasis suppressor, is correlated inversely with the progression and invasion of several tumors. It is capable of inhibiting metastasis without affecting tumorigenicity per se. KAI1/CD82 expression is down-regulated in the progression of common solid epithelial tumors of adulthood. Mutation of p53 is suggested to be involved in the modulation of KAI1. As little is known about its expression and possible prognostic impact in pediatric tumors, we investigated KAI1/CD82 expression in cell lines and primary tumor samples from pediatric tumors of neuroectodermal origin, neuroblastoma and Ewing's sarcoma family tumor. Twenty-four of 29 Ewing's sarcoma family tumor cell lines, independent of p53 status, showed KAI1 mRNA positivity by reverse transcription-PCR analysis in contrast to zero of eight neuroblastoma cell lines. Among 13 primary Ewing's sarcoma family tumor samples from patients with different disease extension, KAI1 mRNA expression was low as detected by reverse transcription-PCR. Twenty of 30 primary neuroblastoma specimens were KAI1-negative by immunofluorescence analysis whereas the remaining 10 gave weak to moderate staining patterns. There was no apparent correlation of KAI1 expression with any clinical or genetic features of the patients whose tumor samples were studied. Consequently, KAI1 may not be of prognostic relevance in this group of tumors although there may be some role for KAI1 modulation in the biology of these neuroectodermal tumors.", 
    "genre": "article", 
    "id": "sg:pub.10.1203/00006450-200208000-00022", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1007352", 
        "issn": [
          "0031-3998", 
          "1530-0447"
        ], 
        "name": "Pediatric Research", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "52"
      }
    ], 
    "keywords": [
      "sarcoma family tumors", 
      "KAI1/CD82 expression", 
      "KAI1/CD82", 
      "tumor samples", 
      "pediatric tumors", 
      "family tumors", 
      "cell lines", 
      "Ewing's sarcoma family tumors", 
      "possible prognostic impact", 
      "CD82 expression", 
      "group of tumors", 
      "common solid epithelial tumors", 
      "KAI1 mRNA expression", 
      "solid epithelial tumors", 
      "primary tumor samples", 
      "mutation of p53", 
      "primary neuroblastoma specimens", 
      "neuroblastoma cell lines", 
      "prognostic impact", 
      "mRNA positivity", 
      "prognostic relevance", 
      "disease extension", 
      "reverse transcription-PCR", 
      "neuroectodermal tumor", 
      "epithelial tumors", 
      "low-level expression", 
      "neuroblastoma specimens", 
      "neuroectodermal origin", 
      "KAI1 expression", 
      "tumors", 
      "tumor cell lines", 
      "mRNA expression", 
      "p53 status", 
      "staining pattern", 
      "reverse transcription-PCR analysis", 
      "transcription-PCR", 
      "genetic features", 
      "KAI1", 
      "immunofluorescence analysis", 
      "metastasis suppressor KAI1/CD82", 
      "metastasis suppressor", 
      "patients", 
      "transcription-PCR analysis", 
      "neuroblastoma", 
      "progression", 
      "transmembrane 4", 
      "expression", 
      "CD82", 
      "level expression", 
      "metastasis", 
      "apparent correlation", 
      "widespread absence", 
      "positivity", 
      "tumorigenicity", 
      "modulation", 
      "adulthood", 
      "p53", 
      "invasion", 
      "status", 
      "group", 
      "suppressor", 
      "samples", 
      "mutations", 
      "lines", 
      "absence", 
      "role", 
      "specimens", 
      "contrast", 
      "correlation", 
      "relevance", 
      "analysis", 
      "patterns", 
      "biology", 
      "impact", 
      "origin", 
      "features", 
      "extension"
    ], 
    "name": "Frequent Low Level Expression in Ewing Sarcoma Family Tumors and Widespread Absence of the Metastasis Suppressor KAI1/CD82 in Neuroblastoma", 
    "pagination": "279-285", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1010230010"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1203/00006450-200208000-00022"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "12149507"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1203/00006450-200208000-00022", 
      "https://app.dimensions.ai/details/publication/pub.1010230010"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-08-04T16:55", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_361.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1203/00006450-200208000-00022"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1203/00006450-200208000-00022'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1203/00006450-200208000-00022'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1203/00006450-200208000-00022'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1203/00006450-200208000-00022'


 

This table displays all metadata directly associated to this object as RDF triples.

267 TRIPLES      21 PREDICATES      124 URIs      113 LITERALS      25 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1203/00006450-200208000-00022 schema:about N002f876ec2524114985fbeeb84f10f66
2 N0e47faff3c9b432e87fd8800cfe2855e
3 N1c2a392ca22844ee912ebdf7b5e28594
4 N2d33eaf1435844b79ad1b8921dbc6b0f
5 N372a2fc05286464bb2bd361237c8fbcc
6 N3b7372e8c85a481f9eb5ab045090ef8f
7 N49db1fdc105d41739b5b858cb9f90447
8 N559f60c68dfa409fb2e7b81fe8a85c01
9 N6e7bfdbc595b4c9691305e5cf8051859
10 N87db27121701401e9b5087e9eac01dd0
11 N8ce6ec02f556400e80c149f2fbe19e8e
12 Nb43cb52ab5a346ca9b271af638f4d5ff
13 Nde0863af43b44a68ae9ebb9d1aeea724
14 Nde375c50705e48bdb977f05565ea76f2
15 Nec482e5639f548ca9ab7f47a57a05951
16 Nf30927c3cacb461f9dd0c935d0732434
17 Nfb540f436bcb4ee88896a33d973d0e68
18 Nfbb21528e373434ca1b6e1328ce12046
19 anzsrc-for:11
20 anzsrc-for:1112
21 schema:author N95a57a6068e84fcbbad9e550be5a9af6
22 schema:citation sg:pub.10.1038/labinvest.3780194
23 sg:pub.10.1038/sj.onc.1201397
24 sg:pub.10.1038/sj.onc.1201852
25 schema:datePublished 2002-08
26 schema:datePublishedReg 2002-08-01
27 schema:description The transmembrane 4 superfamily member KAI1/CD82, a metastasis suppressor, is correlated inversely with the progression and invasion of several tumors. It is capable of inhibiting metastasis without affecting tumorigenicity per se. KAI1/CD82 expression is down-regulated in the progression of common solid epithelial tumors of adulthood. Mutation of p53 is suggested to be involved in the modulation of KAI1. As little is known about its expression and possible prognostic impact in pediatric tumors, we investigated KAI1/CD82 expression in cell lines and primary tumor samples from pediatric tumors of neuroectodermal origin, neuroblastoma and Ewing's sarcoma family tumor. Twenty-four of 29 Ewing's sarcoma family tumor cell lines, independent of p53 status, showed KAI1 mRNA positivity by reverse transcription-PCR analysis in contrast to zero of eight neuroblastoma cell lines. Among 13 primary Ewing's sarcoma family tumor samples from patients with different disease extension, KAI1 mRNA expression was low as detected by reverse transcription-PCR. Twenty of 30 primary neuroblastoma specimens were KAI1-negative by immunofluorescence analysis whereas the remaining 10 gave weak to moderate staining patterns. There was no apparent correlation of KAI1 expression with any clinical or genetic features of the patients whose tumor samples were studied. Consequently, KAI1 may not be of prognostic relevance in this group of tumors although there may be some role for KAI1 modulation in the biology of these neuroectodermal tumors.
28 schema:genre article
29 schema:isAccessibleForFree true
30 schema:isPartOf N16a5eb398a6941ff916d243962e49003
31 Ne5d3d048762a42678e95b39e073afad2
32 sg:journal.1007352
33 schema:keywords CD82
34 CD82 expression
35 Ewing's sarcoma family tumors
36 KAI1
37 KAI1 expression
38 KAI1 mRNA expression
39 KAI1/CD82
40 KAI1/CD82 expression
41 absence
42 adulthood
43 analysis
44 apparent correlation
45 biology
46 cell lines
47 common solid epithelial tumors
48 contrast
49 correlation
50 disease extension
51 epithelial tumors
52 expression
53 extension
54 family tumors
55 features
56 genetic features
57 group
58 group of tumors
59 immunofluorescence analysis
60 impact
61 invasion
62 level expression
63 lines
64 low-level expression
65 mRNA expression
66 mRNA positivity
67 metastasis
68 metastasis suppressor
69 metastasis suppressor KAI1/CD82
70 modulation
71 mutation of p53
72 mutations
73 neuroblastoma
74 neuroblastoma cell lines
75 neuroblastoma specimens
76 neuroectodermal origin
77 neuroectodermal tumor
78 origin
79 p53
80 p53 status
81 patients
82 patterns
83 pediatric tumors
84 positivity
85 possible prognostic impact
86 primary neuroblastoma specimens
87 primary tumor samples
88 prognostic impact
89 prognostic relevance
90 progression
91 relevance
92 reverse transcription-PCR
93 reverse transcription-PCR analysis
94 role
95 samples
96 sarcoma family tumors
97 solid epithelial tumors
98 specimens
99 staining pattern
100 status
101 suppressor
102 transcription-PCR
103 transcription-PCR analysis
104 transmembrane 4
105 tumor cell lines
106 tumor samples
107 tumorigenicity
108 tumors
109 widespread absence
110 schema:name Frequent Low Level Expression in Ewing Sarcoma Family Tumors and Widespread Absence of the Metastasis Suppressor KAI1/CD82 in Neuroblastoma
111 schema:pagination 279-285
112 schema:productId N1e3ca3a02b0046c8bcae117e4c026e61
113 N5badaff8cbea4f708850042c1df29d7f
114 Nd4268fa2ef424012a71eab822970518e
115 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010230010
116 https://doi.org/10.1203/00006450-200208000-00022
117 schema:sdDatePublished 2022-08-04T16:55
118 schema:sdLicense https://scigraph.springernature.com/explorer/license/
119 schema:sdPublisher Nd3a90b339b4d4aadbc486d8766423a04
120 schema:url https://doi.org/10.1203/00006450-200208000-00022
121 sgo:license sg:explorer/license/
122 sgo:sdDataset articles
123 rdf:type schema:ScholarlyArticle
124 N002f876ec2524114985fbeeb84f10f66 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Sarcoma, Ewing
126 rdf:type schema:DefinedTerm
127 N09e73b001e06471286b4bd5b43cc61bf rdf:first sg:person.01112427340.14
128 rdf:rest Nf066e671329749b790e7db8a1ad0c6cd
129 N0e47faff3c9b432e87fd8800cfe2855e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Membrane Glycoproteins
131 rdf:type schema:DefinedTerm
132 N0f776715f0b54117b8d162235f0ae5ec rdf:first sg:person.01161157702.37
133 rdf:rest Nbfa4b10691bc48b5bebf031cb0420ffa
134 N13cca7e2198342c28c07eb531b4d412a rdf:first sg:person.0741362200.35
135 rdf:rest rdf:nil
136 N16a5eb398a6941ff916d243962e49003 schema:issueNumber 2
137 rdf:type schema:PublicationIssue
138 N1c2a392ca22844ee912ebdf7b5e28594 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Bone Neoplasms
140 rdf:type schema:DefinedTerm
141 N1e3ca3a02b0046c8bcae117e4c026e61 schema:name doi
142 schema:value 10.1203/00006450-200208000-00022
143 rdf:type schema:PropertyValue
144 N2d33eaf1435844b79ad1b8921dbc6b0f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Kangai-1 Protein
146 rdf:type schema:DefinedTerm
147 N372a2fc05286464bb2bd361237c8fbcc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Biomarkers, Tumor
149 rdf:type schema:DefinedTerm
150 N3b7372e8c85a481f9eb5ab045090ef8f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Male
152 rdf:type schema:DefinedTerm
153 N3cee1e36a7984b0fb01c10ae94f58a8a rdf:first sg:person.01351015475.40
154 rdf:rest N0f776715f0b54117b8d162235f0ae5ec
155 N49db1fdc105d41739b5b858cb9f90447 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Female
157 rdf:type schema:DefinedTerm
158 N559f60c68dfa409fb2e7b81fe8a85c01 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Proto-Oncogene Proteins
160 rdf:type schema:DefinedTerm
161 N5badaff8cbea4f708850042c1df29d7f schema:name dimensions_id
162 schema:value pub.1010230010
163 rdf:type schema:PropertyValue
164 N6e7bfdbc595b4c9691305e5cf8051859 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Infant
166 rdf:type schema:DefinedTerm
167 N87db27121701401e9b5087e9eac01dd0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Child, Preschool
169 rdf:type schema:DefinedTerm
170 N8ce6ec02f556400e80c149f2fbe19e8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Prognosis
172 rdf:type schema:DefinedTerm
173 N95a57a6068e84fcbbad9e550be5a9af6 rdf:first sg:person.015406057707.62
174 rdf:rest N09e73b001e06471286b4bd5b43cc61bf
175 Nb43cb52ab5a346ca9b271af638f4d5ff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Gene Expression Regulation, Neoplastic
177 rdf:type schema:DefinedTerm
178 Nbfa4b10691bc48b5bebf031cb0420ffa rdf:first sg:person.01362270415.42
179 rdf:rest N13cca7e2198342c28c07eb531b4d412a
180 Nd3a90b339b4d4aadbc486d8766423a04 schema:name Springer Nature - SN SciGraph project
181 rdf:type schema:Organization
182 Nd4268fa2ef424012a71eab822970518e schema:name pubmed_id
183 schema:value 12149507
184 rdf:type schema:PropertyValue
185 Nde0863af43b44a68ae9ebb9d1aeea724 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Genetic Markers
187 rdf:type schema:DefinedTerm
188 Nde375c50705e48bdb977f05565ea76f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Tumor Cells, Cultured
190 rdf:type schema:DefinedTerm
191 Ne5d3d048762a42678e95b39e073afad2 schema:volumeNumber 52
192 rdf:type schema:PublicationVolume
193 Nec482e5639f548ca9ab7f47a57a05951 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
194 schema:name Neuroblastoma
195 rdf:type schema:DefinedTerm
196 Nf066e671329749b790e7db8a1ad0c6cd rdf:first sg:person.0674613533.18
197 rdf:rest N3cee1e36a7984b0fb01c10ae94f58a8a
198 Nf30927c3cacb461f9dd0c935d0732434 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Antigens, CD
200 rdf:type schema:DefinedTerm
201 Nfb540f436bcb4ee88896a33d973d0e68 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
202 schema:name Humans
203 rdf:type schema:DefinedTerm
204 Nfbb21528e373434ca1b6e1328ce12046 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
205 schema:name RNA, Messenger
206 rdf:type schema:DefinedTerm
207 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
208 schema:name Medical and Health Sciences
209 rdf:type schema:DefinedTerm
210 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
211 schema:name Oncology and Carcinogenesis
212 rdf:type schema:DefinedTerm
213 sg:journal.1007352 schema:issn 0031-3998
214 1530-0447
215 schema:name Pediatric Research
216 schema:publisher Springer Nature
217 rdf:type schema:Periodical
218 sg:person.01112427340.14 schema:affiliation grid-institutes:grid.416346.2
219 schema:familyName Ambros
220 schema:givenName Inge
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112427340.14
222 rdf:type schema:Person
223 sg:person.01161157702.37 schema:affiliation grid-institutes:grid.416346.2
224 schema:familyName Luegmayr
225 schema:givenName Andrea
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161157702.37
227 rdf:type schema:Person
228 sg:person.01351015475.40 schema:affiliation grid-institutes:grid.416346.2
229 schema:familyName Muehlbacher
230 schema:givenName Karin
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351015475.40
232 rdf:type schema:Person
233 sg:person.01362270415.42 schema:affiliation grid-institutes:grid.258622.9
234 schema:familyName Yoshie
235 schema:givenName Osamu
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362270415.42
237 rdf:type schema:Person
238 sg:person.015406057707.62 schema:affiliation grid-institutes:grid.416346.2
239 schema:familyName Aryee
240 schema:givenName Dave N T
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015406057707.62
242 rdf:type schema:Person
243 sg:person.0674613533.18 schema:affiliation grid-institutes:grid.416346.2
244 schema:familyName Ambros
245 schema:givenName Peter F
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674613533.18
247 rdf:type schema:Person
248 sg:person.0741362200.35 schema:affiliation grid-institutes:grid.416346.2
249 schema:familyName Kovar
250 schema:givenName Heinrich
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741362200.35
252 rdf:type schema:Person
253 sg:pub.10.1038/labinvest.3780194 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038836006
254 https://doi.org/10.1038/labinvest.3780194
255 rdf:type schema:CreativeWork
256 sg:pub.10.1038/sj.onc.1201397 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004676244
257 https://doi.org/10.1038/sj.onc.1201397
258 rdf:type schema:CreativeWork
259 sg:pub.10.1038/sj.onc.1201852 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043222365
260 https://doi.org/10.1038/sj.onc.1201852
261 rdf:type schema:CreativeWork
262 grid-institutes:grid.258622.9 schema:alternateName Department of Bacteriology, Kinki University School of Medicine, Osaka, Sayama, Japan
263 schema:name Department of Bacteriology, Kinki University School of Medicine, Osaka, Sayama, Japan
264 rdf:type schema:Organization
265 grid-institutes:grid.416346.2 schema:alternateName Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria
266 schema:name Children's Cancer Research Institute (CCRI), St. Anna Kinderspital, A-1090, Vienna, Austria
267 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...