The Dynamics of Brain Concentrations of Phenylalanine and Its Clinical Significance in Patients with Phenylketonuria Determined by in Vivo H ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1995-11

AUTHORS

J Pietz, R Kreis, C Boesch, J Penzien, D Rating, N Herschkowitz

ABSTRACT

Cerebral concentrations of phenylalanine (PHE) were measured by means of quantitative in vivo 1H MR spectroscopy in 8 adult patients treated early for phenylketonuria type I. A 1.5-Tesla routine magnetic resonance scanner, localization sequence with short echo time (20 ms), and a fully automated data processing scheme were used. Baseline plasma PHE concentrations were 1.04 (0.70-1.39) mmol/L PHE with concurrent brain PHE concentrations of 0.27 (0.13-0.41) mmol/kg of wet weight resulting in a plasma/brain ratio of 4.12. Plasma and brain concentrations correlated significantly (Kendall tau b = 0.91, p < 0.01). During an oral load with a single dose of 100 mg L-PHE per kg of body weight in four patients, plasma levels steeply increased. Concurrent brain PHE increase was less steep, was significantly delayed, and still continued up to 20 h postload. Despite the proven rise in plasma and brain concentrations of PHE, neuropsychologic examinations revealed no impairment of attentional and fine motor abilities from preload up to 20 h postload. More... »

PAGES

pr1995266

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005

DOI

http://dx.doi.org/10.1203/00006450-199511000-00005

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036721547

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8552430


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Spectroscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuropsychological Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenylalanine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenylketonurias", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Pediatric Neurology, University of Heidelberg, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pietz", 
        "givenName": "J", 
        "id": "sg:person.0643257562.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643257562.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Spectroscopy and Methodology, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kreis", 
        "givenName": "R", 
        "id": "sg:person.0577112761.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577112761.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Spectroscopy and Methodology, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boesch", 
        "givenName": "C", 
        "id": "sg:person.011326075564.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011326075564.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Pediatrics, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Penzien", 
        "givenName": "J", 
        "id": "sg:person.01356670610.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356670610.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Pediatric Neurology, University of Heidelberg, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rating", 
        "givenName": "D", 
        "id": "sg:person.01233310642.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233310642.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Pediatrics, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Herschkowitz", 
        "givenName": "N", 
        "id": "sg:person.0732503263.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732503263.77"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/mrm.1910310108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001259307"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmrb.1993.1055", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008057503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0140-6736(90)93401-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012400542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0140-6736(90)93401-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012400542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmrb.1995.1084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016207967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(72)90653-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022806075"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(72)90653-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022806075"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1968.tb06202.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033074390"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2788.1983.tb00296.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034867173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1971.tb11979.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036498928"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst0040094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042392089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst0040094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042392089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-8749.1993.tb11552.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042825810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-8749.1993.tb11552.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042825810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/00006450-199006000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045869460", 
          "https://doi.org/10.1203/00006450-199006000-00005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2364(92)90286-g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048105715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archpedi.1991.02160010037012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048150041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1971.tb11980.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048612384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmrb.1993.1056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048964652"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/brain/116.4.811", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059439199"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995-11", 
    "datePublishedReg": "1995-11-01", 
    "description": "Cerebral concentrations of phenylalanine (PHE) were measured by means of quantitative in vivo 1H MR spectroscopy in 8 adult patients treated early for phenylketonuria type I. A 1.5-Tesla routine magnetic resonance scanner, localization sequence with short echo time (20 ms), and a fully automated data processing scheme were used. Baseline plasma PHE concentrations were 1.04 (0.70-1.39) mmol/L PHE with concurrent brain PHE concentrations of 0.27 (0.13-0.41) mmol/kg of wet weight resulting in a plasma/brain ratio of 4.12. Plasma and brain concentrations correlated significantly (Kendall tau b = 0.91, p < 0.01). During an oral load with a single dose of 100 mg L-PHE per kg of body weight in four patients, plasma levels steeply increased. Concurrent brain PHE increase was less steep, was significantly delayed, and still continued up to 20 h postload. Despite the proven rise in plasma and brain concentrations of PHE, neuropsychologic examinations revealed no impairment of attentional and fine motor abilities from preload up to 20 h postload.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1203/00006450-199511000-00005", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1007352", 
        "issn": [
          "0031-3998", 
          "1530-0447"
        ], 
        "name": "Pediatric Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "38"
      }
    ], 
    "name": "The Dynamics of Brain Concentrations of Phenylalanine and Its Clinical Significance in Patients with Phenylketonuria Determined by in Vivo H Magnetic Resonance Spectroscopy", 
    "pagination": "pr1995266", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "aeed7e4427daff2bec7866007a4eb94a7ee8ca72cf30f8d6cbbe151063870f86"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8552430"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0100714"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1203/00006450-199511000-00005"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036721547"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1203/00006450-199511000-00005", 
      "https://app.dimensions.ai/details/publication/pub.1036721547"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000425.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/pr1995266"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'


 

This table displays all metadata directly associated to this object as RDF triples.

197 TRIPLES      21 PREDICATES      55 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1203/00006450-199511000-00005 schema:about N0ece9bba7fb342cc89dcc9c1d83dcf95
2 N3f58272fec9b4bd39a3d2ca6b8194976
3 N74c495768da84b4d84a0242feb7369d8
4 N8054f6faeb824f4bb488c9d43d8a4556
5 N8766ca0ef26c4314b95c577fe378cbf2
6 Na1cb006e2aa04b8f8f281094871e1566
7 Na7207e2f1acf42db86f8f7e586a03e9e
8 Naa2e1bfd95d94d428bec6c9cd5da3ad4
9 Ne6ae3e2579544e6e893dd038c5ddd495
10 Nf50b5035b66c4936975ef64ca252f4f3
11 anzsrc-for:11
12 anzsrc-for:1109
13 schema:author N0b95d8c56a8545e68c8542a59bec7b66
14 schema:citation sg:pub.10.1203/00006450-199006000-00005
15 https://doi.org/10.1001/archpedi.1991.02160010037012
16 https://doi.org/10.1002/mrm.1910310108
17 https://doi.org/10.1006/jmrb.1993.1055
18 https://doi.org/10.1006/jmrb.1993.1056
19 https://doi.org/10.1006/jmrb.1995.1084
20 https://doi.org/10.1016/0006-8993(72)90653-1
21 https://doi.org/10.1016/0022-2364(92)90286-g
22 https://doi.org/10.1016/0140-6736(90)93401-a
23 https://doi.org/10.1042/bst0040094
24 https://doi.org/10.1093/brain/116.4.811
25 https://doi.org/10.1111/j.1365-2788.1983.tb00296.x
26 https://doi.org/10.1111/j.1469-8749.1993.tb11552.x
27 https://doi.org/10.1111/j.1471-4159.1968.tb06202.x
28 https://doi.org/10.1111/j.1471-4159.1971.tb11979.x
29 https://doi.org/10.1111/j.1471-4159.1971.tb11980.x
30 schema:datePublished 1995-11
31 schema:datePublishedReg 1995-11-01
32 schema:description Cerebral concentrations of phenylalanine (PHE) were measured by means of quantitative in vivo 1H MR spectroscopy in 8 adult patients treated early for phenylketonuria type I. A 1.5-Tesla routine magnetic resonance scanner, localization sequence with short echo time (20 ms), and a fully automated data processing scheme were used. Baseline plasma PHE concentrations were 1.04 (0.70-1.39) mmol/L PHE with concurrent brain PHE concentrations of 0.27 (0.13-0.41) mmol/kg of wet weight resulting in a plasma/brain ratio of 4.12. Plasma and brain concentrations correlated significantly (Kendall tau b = 0.91, p < 0.01). During an oral load with a single dose of 100 mg L-PHE per kg of body weight in four patients, plasma levels steeply increased. Concurrent brain PHE increase was less steep, was significantly delayed, and still continued up to 20 h postload. Despite the proven rise in plasma and brain concentrations of PHE, neuropsychologic examinations revealed no impairment of attentional and fine motor abilities from preload up to 20 h postload.
33 schema:genre research_article
34 schema:inLanguage en
35 schema:isAccessibleForFree true
36 schema:isPartOf N75312cc376d24d4896ae4c99e8d05341
37 N99f60a087cf2478bac37ae9360dbef9e
38 sg:journal.1007352
39 schema:name The Dynamics of Brain Concentrations of Phenylalanine and Its Clinical Significance in Patients with Phenylketonuria Determined by in Vivo H Magnetic Resonance Spectroscopy
40 schema:pagination pr1995266
41 schema:productId N29fb593106944b38a3cb17d2feef6ab6
42 N2dd094d7edf44843aa5b4c3338227322
43 N7ec6ba809b474bcbab93fc8347576b41
44 Nb48388911cdd4a758237b930603d003e
45 Nfa274b0d2fd8410687fce20e40780b75
46 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036721547
47 https://doi.org/10.1203/00006450-199511000-00005
48 schema:sdDatePublished 2019-04-10T16:29
49 schema:sdLicense https://scigraph.springernature.com/explorer/license/
50 schema:sdPublisher N47263654373b4ea6af0fdc6e2618e7de
51 schema:url http://www.nature.com/articles/pr1995266
52 sgo:license sg:explorer/license/
53 sgo:sdDataset articles
54 rdf:type schema:ScholarlyArticle
55 N0b95d8c56a8545e68c8542a59bec7b66 rdf:first sg:person.0643257562.30
56 rdf:rest Nc658eb3f3bc0427e8f2b834c256a9fdd
57 N0ece9bba7fb342cc89dcc9c1d83dcf95 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
58 schema:name Brain
59 rdf:type schema:DefinedTerm
60 N29fb593106944b38a3cb17d2feef6ab6 schema:name dimensions_id
61 schema:value pub.1036721547
62 rdf:type schema:PropertyValue
63 N2dd094d7edf44843aa5b4c3338227322 schema:name pubmed_id
64 schema:value 8552430
65 rdf:type schema:PropertyValue
66 N3f58272fec9b4bd39a3d2ca6b8194976 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Neuropsychological Tests
68 rdf:type schema:DefinedTerm
69 N47263654373b4ea6af0fdc6e2618e7de schema:name Springer Nature - SN SciGraph project
70 rdf:type schema:Organization
71 N5eac097914bd4201bed4fa654f1866eb rdf:first sg:person.011326075564.24
72 rdf:rest Nd8608e36f2b14adcab7ba3b94d903674
73 N74c495768da84b4d84a0242feb7369d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Phenylketonurias
75 rdf:type schema:DefinedTerm
76 N75312cc376d24d4896ae4c99e8d05341 schema:volumeNumber 38
77 rdf:type schema:PublicationVolume
78 N7ec6ba809b474bcbab93fc8347576b41 schema:name doi
79 schema:value 10.1203/00006450-199511000-00005
80 rdf:type schema:PropertyValue
81 N8054f6faeb824f4bb488c9d43d8a4556 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Phenylalanine
83 rdf:type schema:DefinedTerm
84 N8766ca0ef26c4314b95c577fe378cbf2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Female
86 rdf:type schema:DefinedTerm
87 N8f584ceb1a664ac39c916980c8ecedf7 rdf:first sg:person.0732503263.77
88 rdf:rest rdf:nil
89 N99f60a087cf2478bac37ae9360dbef9e schema:issueNumber 5
90 rdf:type schema:PublicationIssue
91 Na1cb006e2aa04b8f8f281094871e1566 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Humans
93 rdf:type schema:DefinedTerm
94 Na7207e2f1acf42db86f8f7e586a03e9e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Middle Aged
96 rdf:type schema:DefinedTerm
97 Naa2e1bfd95d94d428bec6c9cd5da3ad4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Magnetic Resonance Spectroscopy
99 rdf:type schema:DefinedTerm
100 Nb48388911cdd4a758237b930603d003e schema:name readcube_id
101 schema:value aeed7e4427daff2bec7866007a4eb94a7ee8ca72cf30f8d6cbbe151063870f86
102 rdf:type schema:PropertyValue
103 Nc658eb3f3bc0427e8f2b834c256a9fdd rdf:first sg:person.0577112761.94
104 rdf:rest N5eac097914bd4201bed4fa654f1866eb
105 Nc925d1a852d44dd18621ac98c208e7ac rdf:first sg:person.01233310642.63
106 rdf:rest N8f584ceb1a664ac39c916980c8ecedf7
107 Nd8608e36f2b14adcab7ba3b94d903674 rdf:first sg:person.01356670610.32
108 rdf:rest Nc925d1a852d44dd18621ac98c208e7ac
109 Ne6ae3e2579544e6e893dd038c5ddd495 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Male
111 rdf:type schema:DefinedTerm
112 Nf50b5035b66c4936975ef64ca252f4f3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Adult
114 rdf:type schema:DefinedTerm
115 Nfa274b0d2fd8410687fce20e40780b75 schema:name nlm_unique_id
116 schema:value 0100714
117 rdf:type schema:PropertyValue
118 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
119 schema:name Medical and Health Sciences
120 rdf:type schema:DefinedTerm
121 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
122 schema:name Neurosciences
123 rdf:type schema:DefinedTerm
124 sg:journal.1007352 schema:issn 0031-3998
125 1530-0447
126 schema:name Pediatric Research
127 rdf:type schema:Periodical
128 sg:person.011326075564.24 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
129 schema:familyName Boesch
130 schema:givenName C
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011326075564.24
132 rdf:type schema:Person
133 sg:person.01233310642.63 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
134 schema:familyName Rating
135 schema:givenName D
136 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233310642.63
137 rdf:type schema:Person
138 sg:person.01356670610.32 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
139 schema:familyName Penzien
140 schema:givenName J
141 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356670610.32
142 rdf:type schema:Person
143 sg:person.0577112761.94 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
144 schema:familyName Kreis
145 schema:givenName R
146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577112761.94
147 rdf:type schema:Person
148 sg:person.0643257562.30 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
149 schema:familyName Pietz
150 schema:givenName J
151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643257562.30
152 rdf:type schema:Person
153 sg:person.0732503263.77 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
154 schema:familyName Herschkowitz
155 schema:givenName N
156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732503263.77
157 rdf:type schema:Person
158 sg:pub.10.1203/00006450-199006000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045869460
159 https://doi.org/10.1203/00006450-199006000-00005
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1001/archpedi.1991.02160010037012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048150041
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1002/mrm.1910310108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001259307
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1006/jmrb.1993.1055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008057503
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1006/jmrb.1993.1056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048964652
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1006/jmrb.1995.1084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016207967
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/0006-8993(72)90653-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022806075
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1016/0022-2364(92)90286-g schema:sameAs https://app.dimensions.ai/details/publication/pub.1048105715
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/0140-6736(90)93401-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1012400542
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1042/bst0040094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042392089
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1093/brain/116.4.811 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059439199
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1111/j.1365-2788.1983.tb00296.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034867173
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1111/j.1469-8749.1993.tb11552.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042825810
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1111/j.1471-4159.1968.tb06202.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033074390
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1111/j.1471-4159.1971.tb11979.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036498928
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1111/j.1471-4159.1971.tb11980.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048612384
190 rdf:type schema:CreativeWork
191 https://www.grid.ac/institutes/grid.5734.5 schema:alternateName University of Bern
192 schema:name Departments of Magnetic Resonance Pediatrics, University of Berne, Switzerland
193 Departments of Magnetic Resonance Spectroscopy and Methodology, University of Berne, Switzerland
194 rdf:type schema:Organization
195 https://www.grid.ac/institutes/grid.7700.0 schema:alternateName Heidelberg University
196 schema:name Department of Pediatric Neurology, University of Heidelberg, Federal Republic of Germany
197 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...