The Dynamics of Brain Concentrations of Phenylalanine and Its Clinical Significance in Patients with Phenylketonuria Determined by in Vivo H ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1995-11

AUTHORS

J Pietz, R Kreis, C Boesch, J Penzien, D Rating, N Herschkowitz

ABSTRACT

Cerebral concentrations of phenylalanine (PHE) were measured by means of quantitative in vivo 1H MR spectroscopy in 8 adult patients treated early for phenylketonuria type I. A 1.5-Tesla routine magnetic resonance scanner, localization sequence with short echo time (20 ms), and a fully automated data processing scheme were used. Baseline plasma PHE concentrations were 1.04 (0.70-1.39) mmol/L PHE with concurrent brain PHE concentrations of 0.27 (0.13-0.41) mmol/kg of wet weight resulting in a plasma/brain ratio of 4.12. Plasma and brain concentrations correlated significantly (Kendall tau b = 0.91, p < 0.01). During an oral load with a single dose of 100 mg L-PHE per kg of body weight in four patients, plasma levels steeply increased. Concurrent brain PHE increase was less steep, was significantly delayed, and still continued up to 20 h postload. Despite the proven rise in plasma and brain concentrations of PHE, neuropsychologic examinations revealed no impairment of attentional and fine motor abilities from preload up to 20 h postload. More... »

PAGES

pr1995266

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005

DOI

http://dx.doi.org/10.1203/00006450-199511000-00005

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036721547

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8552430


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Spectroscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuropsychological Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenylalanine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenylketonurias", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Pediatric Neurology, University of Heidelberg, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pietz", 
        "givenName": "J", 
        "id": "sg:person.0643257562.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643257562.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Spectroscopy and Methodology, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kreis", 
        "givenName": "R", 
        "id": "sg:person.0577112761.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577112761.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Spectroscopy and Methodology, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boesch", 
        "givenName": "C", 
        "id": "sg:person.011326075564.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011326075564.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Pediatrics, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Penzien", 
        "givenName": "J", 
        "id": "sg:person.01356670610.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356670610.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Pediatric Neurology, University of Heidelberg, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rating", 
        "givenName": "D", 
        "id": "sg:person.01233310642.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233310642.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Pediatrics, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Herschkowitz", 
        "givenName": "N", 
        "id": "sg:person.0732503263.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732503263.77"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/mrm.1910310108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001259307"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmrb.1993.1055", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008057503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0140-6736(90)93401-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012400542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0140-6736(90)93401-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012400542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmrb.1995.1084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016207967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(72)90653-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022806075"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(72)90653-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022806075"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1968.tb06202.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033074390"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2788.1983.tb00296.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034867173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1971.tb11979.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036498928"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst0040094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042392089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst0040094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042392089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-8749.1993.tb11552.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042825810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-8749.1993.tb11552.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042825810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/00006450-199006000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045869460", 
          "https://doi.org/10.1203/00006450-199006000-00005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2364(92)90286-g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048105715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archpedi.1991.02160010037012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048150041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1971.tb11980.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048612384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmrb.1993.1056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048964652"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/brain/116.4.811", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059439199"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995-11", 
    "datePublishedReg": "1995-11-01", 
    "description": "Cerebral concentrations of phenylalanine (PHE) were measured by means of quantitative in vivo 1H MR spectroscopy in 8 adult patients treated early for phenylketonuria type I. A 1.5-Tesla routine magnetic resonance scanner, localization sequence with short echo time (20 ms), and a fully automated data processing scheme were used. Baseline plasma PHE concentrations were 1.04 (0.70-1.39) mmol/L PHE with concurrent brain PHE concentrations of 0.27 (0.13-0.41) mmol/kg of wet weight resulting in a plasma/brain ratio of 4.12. Plasma and brain concentrations correlated significantly (Kendall tau b = 0.91, p < 0.01). During an oral load with a single dose of 100 mg L-PHE per kg of body weight in four patients, plasma levels steeply increased. Concurrent brain PHE increase was less steep, was significantly delayed, and still continued up to 20 h postload. Despite the proven rise in plasma and brain concentrations of PHE, neuropsychologic examinations revealed no impairment of attentional and fine motor abilities from preload up to 20 h postload.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1203/00006450-199511000-00005", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1007352", 
        "issn": [
          "0031-3998", 
          "1530-0447"
        ], 
        "name": "Pediatric Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "38"
      }
    ], 
    "name": "The Dynamics of Brain Concentrations of Phenylalanine and Its Clinical Significance in Patients with Phenylketonuria Determined by in Vivo H Magnetic Resonance Spectroscopy", 
    "pagination": "pr1995266", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "aeed7e4427daff2bec7866007a4eb94a7ee8ca72cf30f8d6cbbe151063870f86"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8552430"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0100714"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1203/00006450-199511000-00005"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036721547"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1203/00006450-199511000-00005", 
      "https://app.dimensions.ai/details/publication/pub.1036721547"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000425.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/pr1995266"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'


 

This table displays all metadata directly associated to this object as RDF triples.

197 TRIPLES      21 PREDICATES      55 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1203/00006450-199511000-00005 schema:about N0511efae0d594e8aa21e606a5e6cd7b6
2 N4bd0a478e7004224a52bc1518196248f
3 N88fab66116fd4ce697a25405cc052039
4 N8df973b547fa4f30bd16d6a3aeea5be5
5 N93ed236661fa4c7aa244a2822cce56d2
6 Na7811473567d476a93daf38ff2068e34
7 Nb78a57c7a27942449f8e930abd0f9572
8 Nc38c324807fb4a8589967c7ac746b72a
9 Ne1b7cfb1f49a4652a27f3b5b22744c39
10 Nfd4d4d713d294624b01113f9d1ba5512
11 anzsrc-for:11
12 anzsrc-for:1109
13 schema:author Nf27b935377f94d73b145bbfaa037ce90
14 schema:citation sg:pub.10.1203/00006450-199006000-00005
15 https://doi.org/10.1001/archpedi.1991.02160010037012
16 https://doi.org/10.1002/mrm.1910310108
17 https://doi.org/10.1006/jmrb.1993.1055
18 https://doi.org/10.1006/jmrb.1993.1056
19 https://doi.org/10.1006/jmrb.1995.1084
20 https://doi.org/10.1016/0006-8993(72)90653-1
21 https://doi.org/10.1016/0022-2364(92)90286-g
22 https://doi.org/10.1016/0140-6736(90)93401-a
23 https://doi.org/10.1042/bst0040094
24 https://doi.org/10.1093/brain/116.4.811
25 https://doi.org/10.1111/j.1365-2788.1983.tb00296.x
26 https://doi.org/10.1111/j.1469-8749.1993.tb11552.x
27 https://doi.org/10.1111/j.1471-4159.1968.tb06202.x
28 https://doi.org/10.1111/j.1471-4159.1971.tb11979.x
29 https://doi.org/10.1111/j.1471-4159.1971.tb11980.x
30 schema:datePublished 1995-11
31 schema:datePublishedReg 1995-11-01
32 schema:description Cerebral concentrations of phenylalanine (PHE) were measured by means of quantitative in vivo 1H MR spectroscopy in 8 adult patients treated early for phenylketonuria type I. A 1.5-Tesla routine magnetic resonance scanner, localization sequence with short echo time (20 ms), and a fully automated data processing scheme were used. Baseline plasma PHE concentrations were 1.04 (0.70-1.39) mmol/L PHE with concurrent brain PHE concentrations of 0.27 (0.13-0.41) mmol/kg of wet weight resulting in a plasma/brain ratio of 4.12. Plasma and brain concentrations correlated significantly (Kendall tau b = 0.91, p < 0.01). During an oral load with a single dose of 100 mg L-PHE per kg of body weight in four patients, plasma levels steeply increased. Concurrent brain PHE increase was less steep, was significantly delayed, and still continued up to 20 h postload. Despite the proven rise in plasma and brain concentrations of PHE, neuropsychologic examinations revealed no impairment of attentional and fine motor abilities from preload up to 20 h postload.
33 schema:genre research_article
34 schema:inLanguage en
35 schema:isAccessibleForFree true
36 schema:isPartOf N0a471bc03c2448d38660582e3f8444af
37 N984bf32c38ce4e188f90dd27632acda9
38 sg:journal.1007352
39 schema:name The Dynamics of Brain Concentrations of Phenylalanine and Its Clinical Significance in Patients with Phenylketonuria Determined by in Vivo H Magnetic Resonance Spectroscopy
40 schema:pagination pr1995266
41 schema:productId N5d929a7f807d43b0a0a9fb31daa9eab5
42 N6a7995e4b30e44c79b9455d42df608c9
43 N9c5d41cf01574a16a388b9818d2c20e5
44 Nc096c6029bd94a949cc63ea760066c42
45 Ncf0d55c069244762b4d6d4d62bdfb1b5
46 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036721547
47 https://doi.org/10.1203/00006450-199511000-00005
48 schema:sdDatePublished 2019-04-10T16:29
49 schema:sdLicense https://scigraph.springernature.com/explorer/license/
50 schema:sdPublisher N0a990cf273bb48c3865a3343cdee43b8
51 schema:url http://www.nature.com/articles/pr1995266
52 sgo:license sg:explorer/license/
53 sgo:sdDataset articles
54 rdf:type schema:ScholarlyArticle
55 N0511efae0d594e8aa21e606a5e6cd7b6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
56 schema:name Brain
57 rdf:type schema:DefinedTerm
58 N0a471bc03c2448d38660582e3f8444af schema:issueNumber 5
59 rdf:type schema:PublicationIssue
60 N0a990cf273bb48c3865a3343cdee43b8 schema:name Springer Nature - SN SciGraph project
61 rdf:type schema:Organization
62 N0f8ae7d222bb4f3f8edd32d771867a22 rdf:first sg:person.01356670610.32
63 rdf:rest Nc19ad4be0d434804afdbd7043d052021
64 N27d5ffa7b7bf421c87161496dd5f37db rdf:first sg:person.0732503263.77
65 rdf:rest rdf:nil
66 N4bd0a478e7004224a52bc1518196248f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Adult
68 rdf:type schema:DefinedTerm
69 N563ba83f3b024dedb1156cdfde7d08b3 rdf:first sg:person.011326075564.24
70 rdf:rest N0f8ae7d222bb4f3f8edd32d771867a22
71 N5702961b613d47cf93f5e582088f8509 rdf:first sg:person.0577112761.94
72 rdf:rest N563ba83f3b024dedb1156cdfde7d08b3
73 N5d929a7f807d43b0a0a9fb31daa9eab5 schema:name pubmed_id
74 schema:value 8552430
75 rdf:type schema:PropertyValue
76 N6a7995e4b30e44c79b9455d42df608c9 schema:name doi
77 schema:value 10.1203/00006450-199511000-00005
78 rdf:type schema:PropertyValue
79 N88fab66116fd4ce697a25405cc052039 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Female
81 rdf:type schema:DefinedTerm
82 N8df973b547fa4f30bd16d6a3aeea5be5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Neuropsychological Tests
84 rdf:type schema:DefinedTerm
85 N93ed236661fa4c7aa244a2822cce56d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Humans
87 rdf:type schema:DefinedTerm
88 N984bf32c38ce4e188f90dd27632acda9 schema:volumeNumber 38
89 rdf:type schema:PublicationVolume
90 N9c5d41cf01574a16a388b9818d2c20e5 schema:name dimensions_id
91 schema:value pub.1036721547
92 rdf:type schema:PropertyValue
93 Na7811473567d476a93daf38ff2068e34 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Middle Aged
95 rdf:type schema:DefinedTerm
96 Nb78a57c7a27942449f8e930abd0f9572 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Phenylketonurias
98 rdf:type schema:DefinedTerm
99 Nc096c6029bd94a949cc63ea760066c42 schema:name nlm_unique_id
100 schema:value 0100714
101 rdf:type schema:PropertyValue
102 Nc19ad4be0d434804afdbd7043d052021 rdf:first sg:person.01233310642.63
103 rdf:rest N27d5ffa7b7bf421c87161496dd5f37db
104 Nc38c324807fb4a8589967c7ac746b72a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Magnetic Resonance Spectroscopy
106 rdf:type schema:DefinedTerm
107 Ncf0d55c069244762b4d6d4d62bdfb1b5 schema:name readcube_id
108 schema:value aeed7e4427daff2bec7866007a4eb94a7ee8ca72cf30f8d6cbbe151063870f86
109 rdf:type schema:PropertyValue
110 Ne1b7cfb1f49a4652a27f3b5b22744c39 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Male
112 rdf:type schema:DefinedTerm
113 Nf27b935377f94d73b145bbfaa037ce90 rdf:first sg:person.0643257562.30
114 rdf:rest N5702961b613d47cf93f5e582088f8509
115 Nfd4d4d713d294624b01113f9d1ba5512 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Phenylalanine
117 rdf:type schema:DefinedTerm
118 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
119 schema:name Medical and Health Sciences
120 rdf:type schema:DefinedTerm
121 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
122 schema:name Neurosciences
123 rdf:type schema:DefinedTerm
124 sg:journal.1007352 schema:issn 0031-3998
125 1530-0447
126 schema:name Pediatric Research
127 rdf:type schema:Periodical
128 sg:person.011326075564.24 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
129 schema:familyName Boesch
130 schema:givenName C
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011326075564.24
132 rdf:type schema:Person
133 sg:person.01233310642.63 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
134 schema:familyName Rating
135 schema:givenName D
136 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233310642.63
137 rdf:type schema:Person
138 sg:person.01356670610.32 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
139 schema:familyName Penzien
140 schema:givenName J
141 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356670610.32
142 rdf:type schema:Person
143 sg:person.0577112761.94 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
144 schema:familyName Kreis
145 schema:givenName R
146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577112761.94
147 rdf:type schema:Person
148 sg:person.0643257562.30 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
149 schema:familyName Pietz
150 schema:givenName J
151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643257562.30
152 rdf:type schema:Person
153 sg:person.0732503263.77 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
154 schema:familyName Herschkowitz
155 schema:givenName N
156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732503263.77
157 rdf:type schema:Person
158 sg:pub.10.1203/00006450-199006000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045869460
159 https://doi.org/10.1203/00006450-199006000-00005
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1001/archpedi.1991.02160010037012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048150041
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1002/mrm.1910310108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001259307
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1006/jmrb.1993.1055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008057503
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1006/jmrb.1993.1056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048964652
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1006/jmrb.1995.1084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016207967
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/0006-8993(72)90653-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022806075
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1016/0022-2364(92)90286-g schema:sameAs https://app.dimensions.ai/details/publication/pub.1048105715
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/0140-6736(90)93401-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1012400542
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1042/bst0040094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042392089
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1093/brain/116.4.811 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059439199
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1111/j.1365-2788.1983.tb00296.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034867173
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1111/j.1469-8749.1993.tb11552.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042825810
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1111/j.1471-4159.1968.tb06202.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033074390
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1111/j.1471-4159.1971.tb11979.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036498928
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1111/j.1471-4159.1971.tb11980.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048612384
190 rdf:type schema:CreativeWork
191 https://www.grid.ac/institutes/grid.5734.5 schema:alternateName University of Bern
192 schema:name Departments of Magnetic Resonance Pediatrics, University of Berne, Switzerland
193 Departments of Magnetic Resonance Spectroscopy and Methodology, University of Berne, Switzerland
194 rdf:type schema:Organization
195 https://www.grid.ac/institutes/grid.7700.0 schema:alternateName Heidelberg University
196 schema:name Department of Pediatric Neurology, University of Heidelberg, Federal Republic of Germany
197 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...