The Dynamics of Brain Concentrations of Phenylalanine and Its Clinical Significance in Patients with Phenylketonuria Determined by in Vivo H ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1995-11

AUTHORS

J Pietz, R Kreis, C Boesch, J Penzien, D Rating, N Herschkowitz

ABSTRACT

Cerebral concentrations of phenylalanine (PHE) were measured by means of quantitative in vivo 1H MR spectroscopy in 8 adult patients treated early for phenylketonuria type I. A 1.5-Tesla routine magnetic resonance scanner, localization sequence with short echo time (20 ms), and a fully automated data processing scheme were used. Baseline plasma PHE concentrations were 1.04 (0.70-1.39) mmol/L PHE with concurrent brain PHE concentrations of 0.27 (0.13-0.41) mmol/kg of wet weight resulting in a plasma/brain ratio of 4.12. Plasma and brain concentrations correlated significantly (Kendall tau b = 0.91, p < 0.01). During an oral load with a single dose of 100 mg L-PHE per kg of body weight in four patients, plasma levels steeply increased. Concurrent brain PHE increase was less steep, was significantly delayed, and still continued up to 20 h postload. Despite the proven rise in plasma and brain concentrations of PHE, neuropsychologic examinations revealed no impairment of attentional and fine motor abilities from preload up to 20 h postload. More... »

PAGES

pr1995266

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005

DOI

http://dx.doi.org/10.1203/00006450-199511000-00005

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036721547

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8552430


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Spectroscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuropsychological Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenylalanine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenylketonurias", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Pediatric Neurology, University of Heidelberg, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pietz", 
        "givenName": "J", 
        "id": "sg:person.0643257562.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643257562.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Spectroscopy and Methodology, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kreis", 
        "givenName": "R", 
        "id": "sg:person.0577112761.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577112761.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Spectroscopy and Methodology, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boesch", 
        "givenName": "C", 
        "id": "sg:person.011326075564.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011326075564.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Pediatrics, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Penzien", 
        "givenName": "J", 
        "id": "sg:person.01356670610.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356670610.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg University", 
          "id": "https://www.grid.ac/institutes/grid.7700.0", 
          "name": [
            "Department of Pediatric Neurology, University of Heidelberg, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rating", 
        "givenName": "D", 
        "id": "sg:person.01233310642.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233310642.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Bern", 
          "id": "https://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Departments of Magnetic Resonance Pediatrics, University of Berne, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Herschkowitz", 
        "givenName": "N", 
        "id": "sg:person.0732503263.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732503263.77"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/mrm.1910310108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001259307"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmrb.1993.1055", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008057503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0140-6736(90)93401-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012400542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0140-6736(90)93401-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012400542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmrb.1995.1084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016207967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(72)90653-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022806075"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(72)90653-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022806075"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1968.tb06202.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033074390"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2788.1983.tb00296.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034867173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1971.tb11979.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036498928"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst0040094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042392089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bst0040094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042392089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-8749.1993.tb11552.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042825810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-8749.1993.tb11552.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042825810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/00006450-199006000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045869460", 
          "https://doi.org/10.1203/00006450-199006000-00005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2364(92)90286-g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048105715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archpedi.1991.02160010037012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048150041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1971.tb11980.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048612384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmrb.1993.1056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048964652"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/brain/116.4.811", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059439199"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995-11", 
    "datePublishedReg": "1995-11-01", 
    "description": "Cerebral concentrations of phenylalanine (PHE) were measured by means of quantitative in vivo 1H MR spectroscopy in 8 adult patients treated early for phenylketonuria type I. A 1.5-Tesla routine magnetic resonance scanner, localization sequence with short echo time (20 ms), and a fully automated data processing scheme were used. Baseline plasma PHE concentrations were 1.04 (0.70-1.39) mmol/L PHE with concurrent brain PHE concentrations of 0.27 (0.13-0.41) mmol/kg of wet weight resulting in a plasma/brain ratio of 4.12. Plasma and brain concentrations correlated significantly (Kendall tau b = 0.91, p < 0.01). During an oral load with a single dose of 100 mg L-PHE per kg of body weight in four patients, plasma levels steeply increased. Concurrent brain PHE increase was less steep, was significantly delayed, and still continued up to 20 h postload. Despite the proven rise in plasma and brain concentrations of PHE, neuropsychologic examinations revealed no impairment of attentional and fine motor abilities from preload up to 20 h postload.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1203/00006450-199511000-00005", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1007352", 
        "issn": [
          "0031-3998", 
          "1530-0447"
        ], 
        "name": "Pediatric Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "38"
      }
    ], 
    "name": "The Dynamics of Brain Concentrations of Phenylalanine and Its Clinical Significance in Patients with Phenylketonuria Determined by in Vivo H Magnetic Resonance Spectroscopy", 
    "pagination": "pr1995266", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "aeed7e4427daff2bec7866007a4eb94a7ee8ca72cf30f8d6cbbe151063870f86"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8552430"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0100714"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1203/00006450-199511000-00005"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036721547"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1203/00006450-199511000-00005", 
      "https://app.dimensions.ai/details/publication/pub.1036721547"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000425.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/pr1995266"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1203/00006450-199511000-00005'


 

This table displays all metadata directly associated to this object as RDF triples.

197 TRIPLES      21 PREDICATES      55 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1203/00006450-199511000-00005 schema:about N05029d2e8a54460eaff345eca0e25652
2 N05a0aa59d1c240f2b2697a19d5e27d1a
3 N17ab196319884b6f9abc653ce9ef5060
4 N27be459acd97424cad49e9716a1eca83
5 N2a0b3cdcef144208a48bab6410e95415
6 N3c591a3ce83044dcaaba605cd6c2ced0
7 N44ca3736971b4e2aa63d0ad76a8fb3d3
8 N50142ca61da341a495e90921214aebb4
9 N8489e92149e648629bc44e8be5ebd0b7
10 Neaa92e34fd63429abebad3bec78ec314
11 anzsrc-for:11
12 anzsrc-for:1109
13 schema:author N10effd1ead194d87b62e50295ba013c3
14 schema:citation sg:pub.10.1203/00006450-199006000-00005
15 https://doi.org/10.1001/archpedi.1991.02160010037012
16 https://doi.org/10.1002/mrm.1910310108
17 https://doi.org/10.1006/jmrb.1993.1055
18 https://doi.org/10.1006/jmrb.1993.1056
19 https://doi.org/10.1006/jmrb.1995.1084
20 https://doi.org/10.1016/0006-8993(72)90653-1
21 https://doi.org/10.1016/0022-2364(92)90286-g
22 https://doi.org/10.1016/0140-6736(90)93401-a
23 https://doi.org/10.1042/bst0040094
24 https://doi.org/10.1093/brain/116.4.811
25 https://doi.org/10.1111/j.1365-2788.1983.tb00296.x
26 https://doi.org/10.1111/j.1469-8749.1993.tb11552.x
27 https://doi.org/10.1111/j.1471-4159.1968.tb06202.x
28 https://doi.org/10.1111/j.1471-4159.1971.tb11979.x
29 https://doi.org/10.1111/j.1471-4159.1971.tb11980.x
30 schema:datePublished 1995-11
31 schema:datePublishedReg 1995-11-01
32 schema:description Cerebral concentrations of phenylalanine (PHE) were measured by means of quantitative in vivo 1H MR spectroscopy in 8 adult patients treated early for phenylketonuria type I. A 1.5-Tesla routine magnetic resonance scanner, localization sequence with short echo time (20 ms), and a fully automated data processing scheme were used. Baseline plasma PHE concentrations were 1.04 (0.70-1.39) mmol/L PHE with concurrent brain PHE concentrations of 0.27 (0.13-0.41) mmol/kg of wet weight resulting in a plasma/brain ratio of 4.12. Plasma and brain concentrations correlated significantly (Kendall tau b = 0.91, p < 0.01). During an oral load with a single dose of 100 mg L-PHE per kg of body weight in four patients, plasma levels steeply increased. Concurrent brain PHE increase was less steep, was significantly delayed, and still continued up to 20 h postload. Despite the proven rise in plasma and brain concentrations of PHE, neuropsychologic examinations revealed no impairment of attentional and fine motor abilities from preload up to 20 h postload.
33 schema:genre research_article
34 schema:inLanguage en
35 schema:isAccessibleForFree true
36 schema:isPartOf N367e0cf85331479083d4be86a6479284
37 N61b021f02542470b930fd141b685baae
38 sg:journal.1007352
39 schema:name The Dynamics of Brain Concentrations of Phenylalanine and Its Clinical Significance in Patients with Phenylketonuria Determined by in Vivo H Magnetic Resonance Spectroscopy
40 schema:pagination pr1995266
41 schema:productId N36cf0d96e57f4a039d3defea62422fb1
42 N7d6238919976400faba7152b98a08824
43 Na21bf8884a9b453c956625ab473363aa
44 Nbac811087bc84cab8bd12fa193a06f92
45 Nd12d318dd95d48a4bc56933cc182c889
46 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036721547
47 https://doi.org/10.1203/00006450-199511000-00005
48 schema:sdDatePublished 2019-04-10T16:29
49 schema:sdLicense https://scigraph.springernature.com/explorer/license/
50 schema:sdPublisher Nff52a989770d40b79a08e1f9ccfc79cf
51 schema:url http://www.nature.com/articles/pr1995266
52 sgo:license sg:explorer/license/
53 sgo:sdDataset articles
54 rdf:type schema:ScholarlyArticle
55 N05029d2e8a54460eaff345eca0e25652 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
56 schema:name Phenylalanine
57 rdf:type schema:DefinedTerm
58 N05a0aa59d1c240f2b2697a19d5e27d1a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
59 schema:name Neuropsychological Tests
60 rdf:type schema:DefinedTerm
61 N10effd1ead194d87b62e50295ba013c3 rdf:first sg:person.0643257562.30
62 rdf:rest N2ab55308c90d446cbea03b254437201a
63 N17ab196319884b6f9abc653ce9ef5060 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
64 schema:name Female
65 rdf:type schema:DefinedTerm
66 N27be459acd97424cad49e9716a1eca83 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Humans
68 rdf:type schema:DefinedTerm
69 N2a0b3cdcef144208a48bab6410e95415 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Adult
71 rdf:type schema:DefinedTerm
72 N2ab55308c90d446cbea03b254437201a rdf:first sg:person.0577112761.94
73 rdf:rest Nc3d1b574defe4e52aeae40f80db8ebfa
74 N367e0cf85331479083d4be86a6479284 schema:issueNumber 5
75 rdf:type schema:PublicationIssue
76 N36cf0d96e57f4a039d3defea62422fb1 schema:name readcube_id
77 schema:value aeed7e4427daff2bec7866007a4eb94a7ee8ca72cf30f8d6cbbe151063870f86
78 rdf:type schema:PropertyValue
79 N3c591a3ce83044dcaaba605cd6c2ced0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Middle Aged
81 rdf:type schema:DefinedTerm
82 N44ca3736971b4e2aa63d0ad76a8fb3d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Magnetic Resonance Spectroscopy
84 rdf:type schema:DefinedTerm
85 N50142ca61da341a495e90921214aebb4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Brain
87 rdf:type schema:DefinedTerm
88 N61b021f02542470b930fd141b685baae schema:volumeNumber 38
89 rdf:type schema:PublicationVolume
90 N638106b075224720911c96d1ad4b8437 rdf:first sg:person.0732503263.77
91 rdf:rest rdf:nil
92 N7d6238919976400faba7152b98a08824 schema:name dimensions_id
93 schema:value pub.1036721547
94 rdf:type schema:PropertyValue
95 N8489e92149e648629bc44e8be5ebd0b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Male
97 rdf:type schema:DefinedTerm
98 Na21bf8884a9b453c956625ab473363aa schema:name doi
99 schema:value 10.1203/00006450-199511000-00005
100 rdf:type schema:PropertyValue
101 Nb41601ee749c46bf966efc14b90da010 rdf:first sg:person.01233310642.63
102 rdf:rest N638106b075224720911c96d1ad4b8437
103 Nbac811087bc84cab8bd12fa193a06f92 schema:name pubmed_id
104 schema:value 8552430
105 rdf:type schema:PropertyValue
106 Nc3d1b574defe4e52aeae40f80db8ebfa rdf:first sg:person.011326075564.24
107 rdf:rest Ne7fd1a03c5ac47c5ac6719bcff5dc960
108 Nd12d318dd95d48a4bc56933cc182c889 schema:name nlm_unique_id
109 schema:value 0100714
110 rdf:type schema:PropertyValue
111 Ne7fd1a03c5ac47c5ac6719bcff5dc960 rdf:first sg:person.01356670610.32
112 rdf:rest Nb41601ee749c46bf966efc14b90da010
113 Neaa92e34fd63429abebad3bec78ec314 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Phenylketonurias
115 rdf:type schema:DefinedTerm
116 Nff52a989770d40b79a08e1f9ccfc79cf schema:name Springer Nature - SN SciGraph project
117 rdf:type schema:Organization
118 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
119 schema:name Medical and Health Sciences
120 rdf:type schema:DefinedTerm
121 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
122 schema:name Neurosciences
123 rdf:type schema:DefinedTerm
124 sg:journal.1007352 schema:issn 0031-3998
125 1530-0447
126 schema:name Pediatric Research
127 rdf:type schema:Periodical
128 sg:person.011326075564.24 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
129 schema:familyName Boesch
130 schema:givenName C
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011326075564.24
132 rdf:type schema:Person
133 sg:person.01233310642.63 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
134 schema:familyName Rating
135 schema:givenName D
136 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233310642.63
137 rdf:type schema:Person
138 sg:person.01356670610.32 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
139 schema:familyName Penzien
140 schema:givenName J
141 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356670610.32
142 rdf:type schema:Person
143 sg:person.0577112761.94 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
144 schema:familyName Kreis
145 schema:givenName R
146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577112761.94
147 rdf:type schema:Person
148 sg:person.0643257562.30 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
149 schema:familyName Pietz
150 schema:givenName J
151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643257562.30
152 rdf:type schema:Person
153 sg:person.0732503263.77 schema:affiliation https://www.grid.ac/institutes/grid.5734.5
154 schema:familyName Herschkowitz
155 schema:givenName N
156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732503263.77
157 rdf:type schema:Person
158 sg:pub.10.1203/00006450-199006000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045869460
159 https://doi.org/10.1203/00006450-199006000-00005
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1001/archpedi.1991.02160010037012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048150041
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1002/mrm.1910310108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001259307
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1006/jmrb.1993.1055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008057503
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1006/jmrb.1993.1056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048964652
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1006/jmrb.1995.1084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016207967
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/0006-8993(72)90653-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022806075
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1016/0022-2364(92)90286-g schema:sameAs https://app.dimensions.ai/details/publication/pub.1048105715
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/0140-6736(90)93401-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1012400542
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1042/bst0040094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042392089
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1093/brain/116.4.811 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059439199
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1111/j.1365-2788.1983.tb00296.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034867173
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1111/j.1469-8749.1993.tb11552.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042825810
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1111/j.1471-4159.1968.tb06202.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033074390
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1111/j.1471-4159.1971.tb11979.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036498928
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1111/j.1471-4159.1971.tb11980.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048612384
190 rdf:type schema:CreativeWork
191 https://www.grid.ac/institutes/grid.5734.5 schema:alternateName University of Bern
192 schema:name Departments of Magnetic Resonance Pediatrics, University of Berne, Switzerland
193 Departments of Magnetic Resonance Spectroscopy and Methodology, University of Berne, Switzerland
194 rdf:type schema:Organization
195 https://www.grid.ac/institutes/grid.7700.0 schema:alternateName Heidelberg University
196 schema:name Department of Pediatric Neurology, University of Heidelberg, Federal Republic of Germany
197 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...