The Heterogeneity of the Developing Brain Insulin Receptor View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1988-12

AUTHORS

S Devaskar, L Holtzclaw, F Sadiq

ABSTRACT

ABSTRACT: Comparison of the adult brain insulin receptor (IR) to other tissue IR demonstrates that the former migrates ∼10 kD faster on sodium dodecyl sulfate-polyacrylamide gel electrophoresis due to deficient sialic acid content of the asparagine N-linked carbohydrate moieties. We studied these receptors in the fetal rat (18-day) brain (∼125 kD) and liver (∼135 kD), and demonstrated that similar differences are present during fetal life. These differences are not modified by hyperglycemia associated with both mild hyperinsulinemia and normoinsulinemia/hypoinsulinemia. We further studied the specific brain cell types: neurons, glial cells, and purified microvessel preparation, and demonstrated a heterogeneity in the N-linked glycosylation of the IR within an organ (brain). The neuronal (∼125 kD) and microvascular (∼125 kD, ∼135 kD) IR are deficient in sialic acid, thus conferring neuraminidase-insensitivity to the whole brain, whereas the glial cell IR, similar to the liver IR, exhibits neuraminidase sensitivity and migrates intermediate (∼128 kD) to the liver and brain IR. The functional significance of this receptor heterogeneity between various tissues and cells within the same organ (brain) remains to be determined. More... »

PAGES

683-687

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-198812000-00006

DOI

http://dx.doi.org/10.1203/00006450-198812000-00006

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022734325

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3060828


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Mellitus, Experimental", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Electrophoresis, Polyacrylamide Gel", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fetus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Insulin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neurons", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rabbits", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Inbred Strains", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptor, Insulin", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Division of Neonatology, Department of Pediatrics, St. Louis University and The Pediatric Research Institute, Cardinal Glennon Children's Hospital, 63104, St. Louis, Missouri", 
          "id": "http://www.grid.ac/institutes/grid.413397.b", 
          "name": [
            "Division of Neonatology, Department of Pediatrics, St. Louis University and The Pediatric Research Institute, Cardinal Glennon Children's Hospital, 63104, St. Louis, Missouri"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Devaskar", 
        "givenName": "S", 
        "id": "sg:person.01030214547.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030214547.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Neonatology, Department of Pediatrics, St. Louis University and The Pediatric Research Institute, Cardinal Glennon Children's Hospital, 63104, St. Louis, Missouri", 
          "id": "http://www.grid.ac/institutes/grid.413397.b", 
          "name": [
            "Division of Neonatology, Department of Pediatrics, St. Louis University and The Pediatric Research Institute, Cardinal Glennon Children's Hospital, 63104, St. Louis, Missouri"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Holtzclaw", 
        "givenName": "L", 
        "id": "sg:person.01271574640.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271574640.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Neonatology, Department of Pediatrics, St. Louis University and The Pediatric Research Institute, Cardinal Glennon Children's Hospital, 63104, St. Louis, Missouri", 
          "id": "http://www.grid.ac/institutes/grid.413397.b", 
          "name": [
            "Division of Neonatology, Department of Pediatrics, St. Louis University and The Pediatric Research Institute, Cardinal Glennon Children's Hospital, 63104, St. Louis, Missouri"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sadiq", 
        "givenName": "F", 
        "id": "sg:person.0731463271.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731463271.06"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00281551", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082117451", 
          "https://doi.org/10.1007/bf00281551"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/00006450-198302000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004809798", 
          "https://doi.org/10.1203/00006450-198302000-00006"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/227680a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010419937", 
          "https://doi.org/10.1038/227680a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1988-12", 
    "datePublishedReg": "1988-12-01", 
    "description": "ABSTRACT: Comparison of the adult brain insulin receptor (IR) to other tissue IR demonstrates that the former migrates \u223c10 kD faster on sodium dodecyl sulfate-polyacrylamide gel electrophoresis due to deficient sialic acid content of the asparagine N-linked carbohydrate moieties. We studied these receptors in the fetal rat (18-day) brain (\u223c125 kD) and liver (\u223c135 kD), and demonstrated that similar differences are present during fetal life. These differences are not modified by hyperglycemia associated with both mild hyperinsulinemia and normoinsulinemia/hypoinsulinemia. We further studied the specific brain cell types: neurons, glial cells, and purified microvessel preparation, and demonstrated a heterogeneity in the N-linked glycosylation of the IR within an organ (brain). The neuronal (\u223c125 kD) and microvascular (\u223c125 kD, \u223c135 kD) IR are deficient in sialic acid, thus conferring neuraminidase-insensitivity to the whole brain, whereas the glial cell IR, similar to the liver IR, exhibits neuraminidase sensitivity and migrates intermediate (\u223c128 kD) to the liver and brain IR. The functional significance of this receptor heterogeneity between various tissues and cells within the same organ (brain) remains to be determined.", 
    "genre": "article", 
    "id": "sg:pub.10.1203/00006450-198812000-00006", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1007352", 
        "issn": [
          "0031-3998", 
          "1530-0447"
        ], 
        "name": "Pediatric Research", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "24"
      }
    ], 
    "keywords": [
      "brain insulin receptors", 
      "insulin receptor", 
      "tissue insulin receptors", 
      "cell insulin receptors", 
      "liver insulin receptors", 
      "fetal rat brain", 
      "specific brain cell types", 
      "brain cell types", 
      "mild hyperinsulinemia", 
      "glial cells", 
      "fetal life", 
      "rat brain", 
      "whole brain", 
      "microvessel preparations", 
      "neuraminidase sensitivity", 
      "receptor heterogeneity", 
      "sialic acid content", 
      "receptors", 
      "same organ", 
      "Similar differences", 
      "sialic acid", 
      "brain", 
      "liver", 
      "cell types", 
      "functional significance", 
      "organs", 
      "hyperinsulinemia", 
      "hypoinsulinemia", 
      "hyperglycemia", 
      "cells", 
      "carbohydrate moiety", 
      "neurons", 
      "sodium dodecyl sulfate-polyacrylamide gel electrophoresis", 
      "dodecyl sulfate-polyacrylamide gel electrophoresis", 
      "sulfate-polyacrylamide gel electrophoresis", 
      "differences", 
      "heterogeneity", 
      "tissue", 
      "gel electrophoresis", 
      "Kd", 
      "significance", 
      "life", 
      "asparagine N", 
      "acid content", 
      "sensitivity", 
      "acid", 
      "types", 
      "electrophoresis", 
      "preparation", 
      "comparison", 
      "former migrates", 
      "migrate", 
      "glycosylation", 
      "content", 
      "moiety", 
      "intermediates", 
      "adult brain insulin receptor", 
      "deficient sialic acid content", 
      "normoinsulinemia/hypoinsulinemia", 
      "microvascular (\u223c125 kD, \u223c135 kD) IR", 
      "glial cell IR", 
      "migrates intermediate"
    ], 
    "name": "The Heterogeneity of the Developing Brain Insulin Receptor", 
    "pagination": "683-687", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1022734325"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1203/00006450-198812000-00006"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "3060828"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1203/00006450-198812000-00006", 
      "https://app.dimensions.ai/details/publication/pub.1022734325"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:06", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_218.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1203/00006450-198812000-00006"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1203/00006450-198812000-00006'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1203/00006450-198812000-00006'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1203/00006450-198812000-00006'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1203/00006450-198812000-00006'


 

This table displays all metadata directly associated to this object as RDF triples.

202 TRIPLES      22 PREDICATES      105 URIs      94 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1203/00006450-198812000-00006 schema:about N16e8508912844884b2a5a53e7c590b76
2 N2759e1fa919543809a6e1bd0d352abdd
3 N311ee538ccc84c07ab90774520d49807
4 N75b83d380358452295d4f94748f562cb
5 N845e6daf5b6745d1b3e6f71c53eb7058
6 N8de013d368a847ec8300b86bad65c3cb
7 Na2aee89dc37f4ba2a4c2d7261a00ba6d
8 Nad254a80a19c48fea20d56288d10588d
9 Nb0599fa930604a499d6bd7adf936e638
10 Nc6bfc9b81c414194b0824e526110fb3e
11 Nc9783c941c86483784dadc0d33da712b
12 Nd43c91e8515b4ee48969b8586b43aa18
13 Ne6da7c145d174429ab433329baee62ee
14 anzsrc-for:11
15 anzsrc-for:1109
16 schema:author N2c3ddb4a7f7f4fd38843c0e152d189e6
17 schema:citation sg:pub.10.1007/bf00281551
18 sg:pub.10.1038/227680a0
19 sg:pub.10.1203/00006450-198302000-00006
20 schema:datePublished 1988-12
21 schema:datePublishedReg 1988-12-01
22 schema:description ABSTRACT: Comparison of the adult brain insulin receptor (IR) to other tissue IR demonstrates that the former migrates ∼10 kD faster on sodium dodecyl sulfate-polyacrylamide gel electrophoresis due to deficient sialic acid content of the asparagine N-linked carbohydrate moieties. We studied these receptors in the fetal rat (18-day) brain (∼125 kD) and liver (∼135 kD), and demonstrated that similar differences are present during fetal life. These differences are not modified by hyperglycemia associated with both mild hyperinsulinemia and normoinsulinemia/hypoinsulinemia. We further studied the specific brain cell types: neurons, glial cells, and purified microvessel preparation, and demonstrated a heterogeneity in the N-linked glycosylation of the IR within an organ (brain). The neuronal (∼125 kD) and microvascular (∼125 kD, ∼135 kD) IR are deficient in sialic acid, thus conferring neuraminidase-insensitivity to the whole brain, whereas the glial cell IR, similar to the liver IR, exhibits neuraminidase sensitivity and migrates intermediate (∼128 kD) to the liver and brain IR. The functional significance of this receptor heterogeneity between various tissues and cells within the same organ (brain) remains to be determined.
23 schema:genre article
24 schema:inLanguage en
25 schema:isAccessibleForFree true
26 schema:isPartOf N1c370b5ec076418b989cfe5e617d0600
27 N41a551c9f48d4a10969bfad92dcf239f
28 sg:journal.1007352
29 schema:keywords Kd
30 Similar differences
31 acid
32 acid content
33 adult brain insulin receptor
34 asparagine N
35 brain
36 brain cell types
37 brain insulin receptors
38 carbohydrate moiety
39 cell insulin receptors
40 cell types
41 cells
42 comparison
43 content
44 deficient sialic acid content
45 differences
46 dodecyl sulfate-polyacrylamide gel electrophoresis
47 electrophoresis
48 fetal life
49 fetal rat brain
50 former migrates
51 functional significance
52 gel electrophoresis
53 glial cell IR
54 glial cells
55 glycosylation
56 heterogeneity
57 hyperglycemia
58 hyperinsulinemia
59 hypoinsulinemia
60 insulin receptor
61 intermediates
62 life
63 liver
64 liver insulin receptors
65 microvascular (∼125 kD, ∼135 kD) IR
66 microvessel preparations
67 migrate
68 migrates intermediate
69 mild hyperinsulinemia
70 moiety
71 neuraminidase sensitivity
72 neurons
73 normoinsulinemia/hypoinsulinemia
74 organs
75 preparation
76 rat brain
77 receptor heterogeneity
78 receptors
79 same organ
80 sensitivity
81 sialic acid
82 sialic acid content
83 significance
84 sodium dodecyl sulfate-polyacrylamide gel electrophoresis
85 specific brain cell types
86 sulfate-polyacrylamide gel electrophoresis
87 tissue
88 tissue insulin receptors
89 types
90 whole brain
91 schema:name The Heterogeneity of the Developing Brain Insulin Receptor
92 schema:pagination 683-687
93 schema:productId N2543e57c638b4b119e92748b35bfa762
94 N3cb22d8d99834371811ca1d8bff98cee
95 N5b06d930469041e791e5afc822ca81da
96 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022734325
97 https://doi.org/10.1203/00006450-198812000-00006
98 schema:sdDatePublished 2021-12-01T19:06
99 schema:sdLicense https://scigraph.springernature.com/explorer/license/
100 schema:sdPublisher N4209040b921b4ff4a0b228cac8840a65
101 schema:url https://doi.org/10.1203/00006450-198812000-00006
102 sgo:license sg:explorer/license/
103 sgo:sdDataset articles
104 rdf:type schema:ScholarlyArticle
105 N07d35ca6e1ab4113b12a2d85d7ecc04d rdf:first sg:person.0731463271.06
106 rdf:rest rdf:nil
107 N16e8508912844884b2a5a53e7c590b76 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Neurons
109 rdf:type schema:DefinedTerm
110 N1c370b5ec076418b989cfe5e617d0600 schema:issueNumber 6
111 rdf:type schema:PublicationIssue
112 N2543e57c638b4b119e92748b35bfa762 schema:name doi
113 schema:value 10.1203/00006450-198812000-00006
114 rdf:type schema:PropertyValue
115 N2759e1fa919543809a6e1bd0d352abdd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Liver
117 rdf:type schema:DefinedTerm
118 N2c3ddb4a7f7f4fd38843c0e152d189e6 rdf:first sg:person.01030214547.07
119 rdf:rest Nb1187631f169487ca4770ef115598499
120 N311ee538ccc84c07ab90774520d49807 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Female
122 rdf:type schema:DefinedTerm
123 N3cb22d8d99834371811ca1d8bff98cee schema:name pubmed_id
124 schema:value 3060828
125 rdf:type schema:PropertyValue
126 N41a551c9f48d4a10969bfad92dcf239f schema:volumeNumber 24
127 rdf:type schema:PublicationVolume
128 N4209040b921b4ff4a0b228cac8840a65 schema:name Springer Nature - SN SciGraph project
129 rdf:type schema:Organization
130 N5b06d930469041e791e5afc822ca81da schema:name dimensions_id
131 schema:value pub.1022734325
132 rdf:type schema:PropertyValue
133 N75b83d380358452295d4f94748f562cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Rats
135 rdf:type schema:DefinedTerm
136 N845e6daf5b6745d1b3e6f71c53eb7058 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Fetus
138 rdf:type schema:DefinedTerm
139 N8de013d368a847ec8300b86bad65c3cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Rats, Inbred Strains
141 rdf:type schema:DefinedTerm
142 Na2aee89dc37f4ba2a4c2d7261a00ba6d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Diabetes Mellitus, Experimental
144 rdf:type schema:DefinedTerm
145 Nad254a80a19c48fea20d56288d10588d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Electrophoresis, Polyacrylamide Gel
147 rdf:type schema:DefinedTerm
148 Nb0599fa930604a499d6bd7adf936e638 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Receptor, Insulin
150 rdf:type schema:DefinedTerm
151 Nb1187631f169487ca4770ef115598499 rdf:first sg:person.01271574640.86
152 rdf:rest N07d35ca6e1ab4113b12a2d85d7ecc04d
153 Nc6bfc9b81c414194b0824e526110fb3e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Brain
155 rdf:type schema:DefinedTerm
156 Nc9783c941c86483784dadc0d33da712b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Rabbits
158 rdf:type schema:DefinedTerm
159 Nd43c91e8515b4ee48969b8586b43aa18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Animals
161 rdf:type schema:DefinedTerm
162 Ne6da7c145d174429ab433329baee62ee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Insulin
164 rdf:type schema:DefinedTerm
165 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
166 schema:name Medical and Health Sciences
167 rdf:type schema:DefinedTerm
168 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
169 schema:name Neurosciences
170 rdf:type schema:DefinedTerm
171 sg:journal.1007352 schema:issn 0031-3998
172 1530-0447
173 schema:name Pediatric Research
174 schema:publisher Springer Nature
175 rdf:type schema:Periodical
176 sg:person.01030214547.07 schema:affiliation grid-institutes:grid.413397.b
177 schema:familyName Devaskar
178 schema:givenName S
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030214547.07
180 rdf:type schema:Person
181 sg:person.01271574640.86 schema:affiliation grid-institutes:grid.413397.b
182 schema:familyName Holtzclaw
183 schema:givenName L
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271574640.86
185 rdf:type schema:Person
186 sg:person.0731463271.06 schema:affiliation grid-institutes:grid.413397.b
187 schema:familyName Sadiq
188 schema:givenName F
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731463271.06
190 rdf:type schema:Person
191 sg:pub.10.1007/bf00281551 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082117451
192 https://doi.org/10.1007/bf00281551
193 rdf:type schema:CreativeWork
194 sg:pub.10.1038/227680a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010419937
195 https://doi.org/10.1038/227680a0
196 rdf:type schema:CreativeWork
197 sg:pub.10.1203/00006450-198302000-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004809798
198 https://doi.org/10.1203/00006450-198302000-00006
199 rdf:type schema:CreativeWork
200 grid-institutes:grid.413397.b schema:alternateName Division of Neonatology, Department of Pediatrics, St. Louis University and The Pediatric Research Institute, Cardinal Glennon Children's Hospital, 63104, St. Louis, Missouri
201 schema:name Division of Neonatology, Department of Pediatrics, St. Louis University and The Pediatric Research Institute, Cardinal Glennon Children's Hospital, 63104, St. Louis, Missouri
202 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...