Bone Marrow Examinations In Septic Neutropenic Neonates View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1984-04

AUTHORS

J G Wheeler, J S Abramson, R J Boyle, A R Chauvenet, C A Johnson, S M Block, R J Dillard

ABSTRACT

Bone marrow neutrophil depletion (BMND) has been suggested as a criterion for white blood cell (WBC) transfusions in neonatal sepsis. To determine the incidence of BMND in neonates presenting with signs consistent with sepsis and the relationship of BMND to clinical outcome, bone marrow aspirates were done in 13 neonates (1010-3845 gms) with clinical sepsis and neutropenia. Neutropenia was defined as an absolute peripheral neutrophil count < 1500/mm2 on 2 occasions ≥ 3 hrs apart and BMND was defined as < 7% segs, bands and metamyelocytes per 100 nucleated cells. If BMND was present, patients were randomized to standard treatment (ST) or to ST plus transfusion of irradiated, fresh buffy coat concentrate. 13 of 14 aspirates were interpretable and no complications occurred. Results are as follows: More... »

PAGES

355a

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-198404001-01573

DOI

http://dx.doi.org/10.1203/00006450-198404001-01573

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003892722


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