Leukemic Pulmonary Infiltrates As A Cause Of Respiratory Distress In Children View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1984-04

AUTHORS

K A Starling, M V Gresik, D J Fernbach

ABSTRACT

The clinical and pathological findings in 284 children with acute leukemia who had autopsies over a 22-year period were examined to determine the incidence of pulmonary leukemic infiltrates at the time of death. Six children (2.1%) had acute monocytic leukemia (AMoL), 33 (11.6%) had acute myelogenous or acute monomyelogenous leukemia (AMML) and 245 (86.3%) had acute lymphoid leukemia (ALL). Forty-one of 284 children (14.4%) were found to have 3 distinctive patterns of pulmonary infiltrate. Eleven children (6 ALL, 4 AMML, 1 AMoL) had interstitial infiltrates with or without pleural infiltrates. Seven children (4 ALL, 3 AMML) had parenchymal nodules. Twenty-three children (20 ALL, 2 AMoL, 1 AMML) had perivascular infiltrates with or without peribronchial infiltrates. The presence or absence of infiltrates could not be correlated with leukemic cell type, immunologic phenotype, sex, or white blood cell count at the time of death. Ten of 41 children had respiratory distress (RD) prior to death; however, only 2 of 41 (4.9%) or 2 of 284 (0.7%) had RD which was not explained by active pulmonary infection. We conclude that despite reports of leukemic infiltrates presenting as interstitial pneumonia, pulmonary leukemic infiltrates are a rare cause of RD in the terminally ill child with leukemia. More... »

PAGES

249a

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-198404001-00936

DOI

http://dx.doi.org/10.1203/00006450-198404001-00936

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1002699074


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "familyName": "Starling", 
        "givenName": "K A", 
        "id": "sg:person.065570553.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.065570553.31"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Gresik", 
        "givenName": "M V", 
        "id": "sg:person.01100414254.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100414254.89"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Fernbach", 
        "givenName": "D J", 
        "id": "sg:person.0107756265.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0107756265.97"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1984-04", 
    "datePublishedReg": "1984-04-01", 
    "description": "The clinical and pathological findings in 284 children with acute leukemia who had autopsies over a 22-year period were examined to determine the incidence of pulmonary leukemic infiltrates at the time of death. Six children (2.1%) had acute monocytic leukemia (AMoL), 33 (11.6%) had acute myelogenous or acute monomyelogenous leukemia (AMML) and 245 (86.3%) had acute lymphoid leukemia (ALL). Forty-one of 284 children (14.4%) were found to have 3 distinctive patterns of pulmonary infiltrate. Eleven children (6 ALL, 4 AMML, 1 AMoL) had interstitial infiltrates with or without pleural infiltrates. Seven children (4 ALL, 3 AMML) had parenchymal nodules. Twenty-three children (20 ALL, 2 AMoL, 1 AMML) had perivascular infiltrates with or without peribronchial infiltrates. The presence or absence of infiltrates could not be correlated with leukemic cell type, immunologic phenotype, sex, or white blood cell count at the time of death. Ten of 41 children had respiratory distress (RD) prior to death; however, only 2 of 41 (4.9%) or 2 of 284 (0.7%) had RD which was not explained by active pulmonary infection. We conclude that despite reports of leukemic infiltrates presenting as interstitial pneumonia, pulmonary leukemic infiltrates are a rare cause of RD in the terminally ill child with leukemia.", 
    "genre": "non_research_article", 
    "id": "sg:pub.10.1203/00006450-198404001-00936", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1007352", 
        "issn": [
          "0031-3998", 
          "1530-0447"
        ], 
        "name": "Pediatric Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "S4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "18"
      }
    ], 
    "name": "LEUKEMIC PULMONARY INFILTRATES AS A CAUSE OF RESPIRATORY DISTRESS IN CHILDREN", 
    "pagination": "249a", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "0cd9dd715c708b45cf8bf7559daa397ed4564de2939e2c89b2202407edc78422"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1203/00006450-198404001-00936"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1002699074"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1203/00006450-198404001-00936", 
      "https://app.dimensions.ai/details/publication/pub.1002699074"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:28", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000421.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/pr19841015"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1203/00006450-198404001-00936'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1203/00006450-198404001-00936'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1203/00006450-198404001-00936'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1203/00006450-198404001-00936'


 

This table displays all metadata directly associated to this object as RDF triples.

69 TRIPLES      20 PREDICATES      27 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1203/00006450-198404001-00936 schema:about anzsrc-for:11
2 anzsrc-for:1102
3 schema:author N7d30120b75554331a0008cdc6a0f0614
4 schema:datePublished 1984-04
5 schema:datePublishedReg 1984-04-01
6 schema:description The clinical and pathological findings in 284 children with acute leukemia who had autopsies over a 22-year period were examined to determine the incidence of pulmonary leukemic infiltrates at the time of death. Six children (2.1%) had acute monocytic leukemia (AMoL), 33 (11.6%) had acute myelogenous or acute monomyelogenous leukemia (AMML) and 245 (86.3%) had acute lymphoid leukemia (ALL). Forty-one of 284 children (14.4%) were found to have 3 distinctive patterns of pulmonary infiltrate. Eleven children (6 ALL, 4 AMML, 1 AMoL) had interstitial infiltrates with or without pleural infiltrates. Seven children (4 ALL, 3 AMML) had parenchymal nodules. Twenty-three children (20 ALL, 2 AMoL, 1 AMML) had perivascular infiltrates with or without peribronchial infiltrates. The presence or absence of infiltrates could not be correlated with leukemic cell type, immunologic phenotype, sex, or white blood cell count at the time of death. Ten of 41 children had respiratory distress (RD) prior to death; however, only 2 of 41 (4.9%) or 2 of 284 (0.7%) had RD which was not explained by active pulmonary infection. We conclude that despite reports of leukemic infiltrates presenting as interstitial pneumonia, pulmonary leukemic infiltrates are a rare cause of RD in the terminally ill child with leukemia.
7 schema:genre non_research_article
8 schema:inLanguage en
9 schema:isAccessibleForFree true
10 schema:isPartOf N503d79533cf94fe6afa888d83987e73a
11 N8fd953bdb38f4ac4a9ed7d4d30955362
12 sg:journal.1007352
13 schema:name LEUKEMIC PULMONARY INFILTRATES AS A CAUSE OF RESPIRATORY DISTRESS IN CHILDREN
14 schema:pagination 249a
15 schema:productId N5dd26e2eb47e46ba9e48609196d2e5f6
16 N76061cc38c984f3caad662be66b6da2f
17 Nca39e84cdfb548debe9b6ba71c08f443
18 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002699074
19 https://doi.org/10.1203/00006450-198404001-00936
20 schema:sdDatePublished 2019-04-10T16:28
21 schema:sdLicense https://scigraph.springernature.com/explorer/license/
22 schema:sdPublisher N599feadc65bd48d8b46ad5a03592726b
23 schema:url https://www.nature.com/articles/pr19841015
24 sgo:license sg:explorer/license/
25 sgo:sdDataset articles
26 rdf:type schema:ScholarlyArticle
27 N503d79533cf94fe6afa888d83987e73a schema:issueNumber S4
28 rdf:type schema:PublicationIssue
29 N599feadc65bd48d8b46ad5a03592726b schema:name Springer Nature - SN SciGraph project
30 rdf:type schema:Organization
31 N5dd26e2eb47e46ba9e48609196d2e5f6 schema:name readcube_id
32 schema:value 0cd9dd715c708b45cf8bf7559daa397ed4564de2939e2c89b2202407edc78422
33 rdf:type schema:PropertyValue
34 N735add9b504c423786a2aed5e5176f77 rdf:first sg:person.01100414254.89
35 rdf:rest N8299ad9ddd5141ffb5a321caf2acf3c3
36 N76061cc38c984f3caad662be66b6da2f schema:name dimensions_id
37 schema:value pub.1002699074
38 rdf:type schema:PropertyValue
39 N7d30120b75554331a0008cdc6a0f0614 rdf:first sg:person.065570553.31
40 rdf:rest N735add9b504c423786a2aed5e5176f77
41 N8299ad9ddd5141ffb5a321caf2acf3c3 rdf:first sg:person.0107756265.97
42 rdf:rest rdf:nil
43 N8fd953bdb38f4ac4a9ed7d4d30955362 schema:volumeNumber 18
44 rdf:type schema:PublicationVolume
45 Nca39e84cdfb548debe9b6ba71c08f443 schema:name doi
46 schema:value 10.1203/00006450-198404001-00936
47 rdf:type schema:PropertyValue
48 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
49 schema:name Medical and Health Sciences
50 rdf:type schema:DefinedTerm
51 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
52 schema:name Cardiorespiratory Medicine and Haematology
53 rdf:type schema:DefinedTerm
54 sg:journal.1007352 schema:issn 0031-3998
55 1530-0447
56 schema:name Pediatric Research
57 rdf:type schema:Periodical
58 sg:person.0107756265.97 schema:familyName Fernbach
59 schema:givenName D J
60 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0107756265.97
61 rdf:type schema:Person
62 sg:person.01100414254.89 schema:familyName Gresik
63 schema:givenName M V
64 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100414254.89
65 rdf:type schema:Person
66 sg:person.065570553.31 schema:familyName Starling
67 schema:givenName K A
68 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.065570553.31
69 rdf:type schema:Person
 




Preview window. Press ESC to close (or click here)


...