What Constitutes Gh Deficiency? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1984-04

AUTHORS

Bessie E Spiliotis, Gilbert August, Wellington Hung, Barry B Bercu

ABSTRACT

Classic GH deficiency is defined on the basis of provocative tests in the appropriate clinical setting. Some authors have proposed that a suitable nocturnal GH level is a useful physiologic index in normal children. Using standard provocative as well as physiologic (q20 min × 24h) testing, we have studied 18 GH deficient and 11 short (ht <1%tile) control children. The GH deficient group was divided into 3 based on the highest peak GH after provocative tests: severe (< 5.0 ng/ml), moderate (5.0-6.9 ng/ml) and partial (7.0-9.9 ng/ml) GH deficiency. The data are summarized:Our data confirm that GH deficiency can be diagnosed with standard provocative tests, however, physiologic GH measurements such as nocturnal (and even daytime) sampling can sometimes be misleading. Twenty-four hour studies (and integrated GH cone.) are helpful in better understanding the neuroregulatory control of GH secretion as well as giving a more precise analysis of GH output. More... »

PAGES

177-177

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-198404001-00506

DOI

http://dx.doi.org/10.1203/00006450-198404001-00506

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011206703


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Children's Hosp. National Med. Ctr., GW University", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Pregnancy Research Branch, NICHD, NIH, 20205, Bethesda, MD", 
            "Children's Hosp. National Med. Ctr., GW University"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Spiliotis", 
        "givenName": "Bessie E", 
        "id": "sg:person.01016426537.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016426537.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children's Hosp. National Med. Ctr., GW University", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Pregnancy Research Branch, NICHD, NIH, 20205, Bethesda, MD", 
            "Children's Hosp. National Med. Ctr., GW University"
          ], 
          "type": "Organization"
        }, 
        "familyName": "August", 
        "givenName": "Gilbert", 
        "id": "sg:person.01355356357.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01355356357.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children's Hosp. National Med. Ctr., GW University", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Pregnancy Research Branch, NICHD, NIH, 20205, Bethesda, MD", 
            "Children's Hosp. National Med. Ctr., GW University"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hung", 
        "givenName": "Wellington", 
        "id": "sg:person.0721111567.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721111567.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children's Hosp. National Med. Ctr., GW University", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Pregnancy Research Branch, NICHD, NIH, 20205, Bethesda, MD", 
            "Children's Hosp. National Med. Ctr., GW University"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bercu", 
        "givenName": "Barry B", 
        "id": "sg:person.015266733535.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015266733535.42"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1984-04", 
    "datePublishedReg": "1984-04-01", 
    "description": "Classic GH deficiency is defined on the basis of provocative tests in the appropriate clinical setting. Some authors have proposed that a suitable nocturnal GH level is a useful physiologic index in normal children. Using standard provocative as well as physiologic (q20 min \u00d7 24h) testing, we have studied 18 GH deficient and 11 short (ht <1%tile) control children. The GH deficient group was divided into 3 based on the highest peak GH after provocative tests: severe (< 5.0 ng/ml), moderate (5.0-6.9 ng/ml) and partial (7.0-9.9 ng/ml) GH deficiency. The data are summarized:Our data confirm that GH deficiency can be diagnosed with standard provocative tests, however, physiologic GH measurements such as nocturnal (and even daytime) sampling can sometimes be misleading. Twenty-four hour studies (and integrated GH cone.) are helpful in better understanding the neuroregulatory control of GH secretion as well as giving a more precise analysis of GH output.", 
    "genre": "article", 
    "id": "sg:pub.10.1203/00006450-198404001-00506", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1007352", 
        "issn": [
          "0031-3998", 
          "1530-0447"
        ], 
        "name": "Pediatric Research", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "Suppl 4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "18"
      }
    ], 
    "keywords": [
      "GH deficiency", 
      "provocative tests", 
      "nocturnal GH levels", 
      "GH deficient group", 
      "higher peak GH", 
      "standard provocative tests", 
      "appropriate clinical setting", 
      "partial GH deficiency", 
      "classic GH deficiency", 
      "peak GH", 
      "GH secretion", 
      "GH output", 
      "GH levels", 
      "physiologic testing", 
      "deficient group", 
      "GH measurements", 
      "physiologic indices", 
      "neuroregulatory control", 
      "clinical setting", 
      "control children", 
      "normal children", 
      "hour study", 
      "GH", 
      "deficiency", 
      "children", 
      "secretion", 
      "test", 
      "nocturnal sampling", 
      "group", 
      "setting", 
      "index", 
      "levels", 
      "data", 
      "control", 
      "testing", 
      "study", 
      "authors", 
      "sampling", 
      "analysis", 
      "precise analysis", 
      "basis", 
      "measurements", 
      "output", 
      "suitable nocturnal GH level", 
      "useful physiologic index", 
      "short (ht <1%tile) control children", 
      "physiologic GH measurements"
    ], 
    "name": "WHAT CONSTITUTES GH DEFICIENCY?", 
    "pagination": "177-177", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1011206703"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1203/00006450-198404001-00506"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1203/00006450-198404001-00506", 
      "https://app.dimensions.ai/details/publication/pub.1011206703"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:02", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_163.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1203/00006450-198404001-00506"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1203/00006450-198404001-00506'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1203/00006450-198404001-00506'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1203/00006450-198404001-00506'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1203/00006450-198404001-00506'


 

This table displays all metadata directly associated to this object as RDF triples.

127 TRIPLES      21 PREDICATES      73 URIs      65 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1203/00006450-198404001-00506 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author Nd3642c14190e45068099c626e18d81e8
4 schema:datePublished 1984-04
5 schema:datePublishedReg 1984-04-01
6 schema:description Classic GH deficiency is defined on the basis of provocative tests in the appropriate clinical setting. Some authors have proposed that a suitable nocturnal GH level is a useful physiologic index in normal children. Using standard provocative as well as physiologic (q20 min × 24h) testing, we have studied 18 GH deficient and 11 short (ht <1%tile) control children. The GH deficient group was divided into 3 based on the highest peak GH after provocative tests: severe (< 5.0 ng/ml), moderate (5.0-6.9 ng/ml) and partial (7.0-9.9 ng/ml) GH deficiency. The data are summarized:Our data confirm that GH deficiency can be diagnosed with standard provocative tests, however, physiologic GH measurements such as nocturnal (and even daytime) sampling can sometimes be misleading. Twenty-four hour studies (and integrated GH cone.) are helpful in better understanding the neuroregulatory control of GH secretion as well as giving a more precise analysis of GH output.
7 schema:genre article
8 schema:inLanguage en
9 schema:isAccessibleForFree true
10 schema:isPartOf N2a37712713ab48c5aea496000b3732e7
11 Nf5540bbdafc4471d8329875872faf593
12 sg:journal.1007352
13 schema:keywords GH
14 GH deficiency
15 GH deficient group
16 GH levels
17 GH measurements
18 GH output
19 GH secretion
20 analysis
21 appropriate clinical setting
22 authors
23 basis
24 children
25 classic GH deficiency
26 clinical setting
27 control
28 control children
29 data
30 deficiency
31 deficient group
32 group
33 higher peak GH
34 hour study
35 index
36 levels
37 measurements
38 neuroregulatory control
39 nocturnal GH levels
40 nocturnal sampling
41 normal children
42 output
43 partial GH deficiency
44 peak GH
45 physiologic GH measurements
46 physiologic indices
47 physiologic testing
48 precise analysis
49 provocative tests
50 sampling
51 secretion
52 setting
53 short (ht <1%tile) control children
54 standard provocative tests
55 study
56 suitable nocturnal GH level
57 test
58 testing
59 useful physiologic index
60 schema:name WHAT CONSTITUTES GH DEFICIENCY?
61 schema:pagination 177-177
62 schema:productId N7835d37575d4496f81b736afc97b56d3
63 N9dbdf34536ce4ea8bbe60b462c9a09e6
64 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011206703
65 https://doi.org/10.1203/00006450-198404001-00506
66 schema:sdDatePublished 2022-01-01T18:02
67 schema:sdLicense https://scigraph.springernature.com/explorer/license/
68 schema:sdPublisher Nd29488038e394b9c8890520c6a1f9137
69 schema:url https://doi.org/10.1203/00006450-198404001-00506
70 sgo:license sg:explorer/license/
71 sgo:sdDataset articles
72 rdf:type schema:ScholarlyArticle
73 N0b180e8d6e164d688873a9937387dc58 rdf:first sg:person.01355356357.08
74 rdf:rest N6b7023cc4f2a4c318a2beee1c31622a7
75 N2a37712713ab48c5aea496000b3732e7 schema:issueNumber Suppl 4
76 rdf:type schema:PublicationIssue
77 N6b7023cc4f2a4c318a2beee1c31622a7 rdf:first sg:person.0721111567.21
78 rdf:rest N7a59f7b6ecbc422e90cf1ef8dd0143b5
79 N7835d37575d4496f81b736afc97b56d3 schema:name dimensions_id
80 schema:value pub.1011206703
81 rdf:type schema:PropertyValue
82 N7a59f7b6ecbc422e90cf1ef8dd0143b5 rdf:first sg:person.015266733535.42
83 rdf:rest rdf:nil
84 N9dbdf34536ce4ea8bbe60b462c9a09e6 schema:name doi
85 schema:value 10.1203/00006450-198404001-00506
86 rdf:type schema:PropertyValue
87 Nd29488038e394b9c8890520c6a1f9137 schema:name Springer Nature - SN SciGraph project
88 rdf:type schema:Organization
89 Nd3642c14190e45068099c626e18d81e8 rdf:first sg:person.01016426537.55
90 rdf:rest N0b180e8d6e164d688873a9937387dc58
91 Nf5540bbdafc4471d8329875872faf593 schema:volumeNumber 18
92 rdf:type schema:PublicationVolume
93 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
94 schema:name Medical and Health Sciences
95 rdf:type schema:DefinedTerm
96 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
97 schema:name Clinical Sciences
98 rdf:type schema:DefinedTerm
99 sg:journal.1007352 schema:issn 0031-3998
100 1530-0447
101 schema:name Pediatric Research
102 schema:publisher Springer Nature
103 rdf:type schema:Periodical
104 sg:person.01016426537.55 schema:affiliation grid-institutes:None
105 schema:familyName Spiliotis
106 schema:givenName Bessie E
107 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016426537.55
108 rdf:type schema:Person
109 sg:person.01355356357.08 schema:affiliation grid-institutes:None
110 schema:familyName August
111 schema:givenName Gilbert
112 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01355356357.08
113 rdf:type schema:Person
114 sg:person.015266733535.42 schema:affiliation grid-institutes:None
115 schema:familyName Bercu
116 schema:givenName Barry B
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015266733535.42
118 rdf:type schema:Person
119 sg:person.0721111567.21 schema:affiliation grid-institutes:None
120 schema:familyName Hung
121 schema:givenName Wellington
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721111567.21
123 rdf:type schema:Person
124 grid-institutes:None schema:alternateName Children's Hosp. National Med. Ctr., GW University
125 schema:name Children's Hosp. National Med. Ctr., GW University
126 Pregnancy Research Branch, NICHD, NIH, 20205, Bethesda, MD
127 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...