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    "description": "DPA and determination of an aortic diastolic time constant, \u03c4, has been utilized to evaluate two groups of neonates: the first with left to right ductal shunting; and the second with no ductal shunting. In earlier studies performed manually, \u03c4, which is the reciprocal of the slope of the log of the diastolic pressure plotted against time, was 400 \u00b1 57 msec (1 S.D.) in group I and 657 \u00b1 62 msec in group II. A microcomputer system suitable for continuous \u03c4 determinations is described.Arterial pressure pulses are obtained from umbilical aortic catheters which are connected to a standard amplification system. The analog signal is then transmitted to an analog-to-digital convertor of a microcomputer which samples at the rate of 100 times/sec. These data are then used to determine the instantaneous slopes between successive samples on each pressure cycle to enable the automated recognition of the dicrotic notch and the onset of systole. Once the diastolic portion of each beat is identified and meets certain quality criteria, eight equally spaced points are selected in diastole and a least squares fit is made to an exponential curve and the \u03c4 is determined. Current on-line \u03c4 determinations are performed over 25 second intervals every ten minutes and the mean \u03c4 and standard deviation are recorded. Subsequent trend analysis as a means to determine the predictive value of \u03c4 is anticipated.", 
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        "issn": [
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        "name": "Pediatric Research", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
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      {
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    "name": "140 CONTINUOUS COMPUTERIZED DIASTOLIC PRESSURE ANALYSIS (DPA) IN NEONATES", 
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