Effect of 4-Pentenoate on Rat Liver Ornithine Transcarbamylase View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1977-04

AUTHORS

Allen M Glasgow

ABSTRACT

The effect of 4-pentenoate on rat liver ornithine transcarbamylase was studied. No effect was found. It is concluded that the effect of 4-pentenoic acid on ornithine transcarbamylase reported by others was probably due to technical errors. Available evidence indicates that 4-pentenoate inhibits ureagenesis by interfering with mitochondrial energy metabolism, which in turn impairs mitochondrial ornithine transport or depletes mitochondrial ATP, impairing carbamyl phosphate synthesis, or both. More... »

PAGES

303

Identifiers

URI

http://scigraph.springernature.com/pub.10.1203/00006450-197704000-00009

DOI

http://dx.doi.org/10.1203/00006450-197704000-00009

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1038274681

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/846784


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